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[Primary malignant bone tumours-part II]. [原发性恶性骨肿瘤ⅱ]。
IF 0.6
Radiologie (Heidelberg, Germany) Pub Date : 2026-06-01 Epub Date: 2026-05-11 DOI: 10.1007/s00117-026-01618-2
Thomas Grieser
{"title":"[Primary malignant bone tumours-part II].","authors":"Thomas Grieser","doi":"10.1007/s00117-026-01618-2","DOIUrl":"10.1007/s00117-026-01618-2","url":null,"abstract":"<p><p>Chondrosarcomas are tumours that typically occur in older adults. Although a few arise de novo, they often develop from pre-existing enchondromas, much more frequently from osteochondromas. In these secondary chondrosarcomas, the primary site of pre-existing chondrogenic lesion plays an important role (close to the trunk, centrally; appendicular skeleton, peripherally). Thus, low-grade chondrosarcomas in the periphery are referred to as atypical chondrogenic tumours (ACT), whereas tumours of the same histopathological type located close to the axial skeleton are called chondrosarcoma grade 1. Syndromal occurrence (Ollier's and Maffucci's diseases) carries a significantly higher risk of malignant transformation. Other malignant primary bone tumours being much less frequent exhibit an unspecific osteolytic morphology but sometimes at a typical location (chordoma: sacrococcygeal region; adamantinoma: tibial shaft; malignant giant-cell tumor [GCT]: epi-metaphyseal expansion). Subsequent histological evaluation frequently reveals the (unexpected) diagnosis. For this reason, one section will focus on tumour mimics and differentiation from benign bone lesions. In this respect, some associated aspects of the well-known Lodwick (Madewell) classifications are discussed in order to highlight three very peculiar bone tumour-associated imaging phenomena (periosteal reactions, aneurysmatic bone cyst-like changes, peritumoral reactive zones).</p>","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":" ","pages":"432-445"},"PeriodicalIF":0.6,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147870744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Multiple soft tissue swellings : Computed tomography as the basis for complex tumour detection]. [多发性软组织肿胀:计算机断层扫描作为复杂肿瘤检测的基础]。
IF 0.6
Radiologie (Heidelberg, Germany) Pub Date : 2026-06-01 Epub Date: 2026-04-07 DOI: 10.1007/s00117-026-01590-x
Melisa Özgüneyli, Daaje Reents, Suzan Abu Zanat, Sophia Engel
{"title":"[Multiple soft tissue swellings : Computed tomography as the basis for complex tumour detection].","authors":"Melisa Özgüneyli, Daaje Reents, Suzan Abu Zanat, Sophia Engel","doi":"10.1007/s00117-026-01590-x","DOIUrl":"10.1007/s00117-026-01590-x","url":null,"abstract":"","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":" ","pages":"467-470"},"PeriodicalIF":0.6,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13226367/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147629436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Positron emission tomography in sarcomas]. [肉瘤的正电子发射断层扫描]。
IF 0.6
Radiologie (Heidelberg, Germany) Pub Date : 2026-06-01 Epub Date: 2026-02-17 DOI: 10.1007/s00117-026-01573-y
Wolfgang P Fendler, Lukas Kessler, Stephan Himmen, Rainer Hamacher
{"title":"[Positron emission tomography in sarcomas].","authors":"Wolfgang P Fendler, Lukas Kessler, Stephan Himmen, Rainer Hamacher","doi":"10.1007/s00117-026-01573-y","DOIUrl":"10.1007/s00117-026-01573-y","url":null,"abstract":"<p><strong>Background: </strong>Sarcomas are rare, heterogeneous tumors of mesenchymal origin. Molecular imaging is crucial for diagnosis, staging, and therapy monitoring. <sup>18</sup>F‑Fluorodeoxyglucose (<sup>18</sup>F‑FDG) positron-emission tomography/computed tomography (PET/CT) is a powerful technique for imaging high-grade soft tissue and bone sarcomas and supports staging, grading, biopsy targeting, and risk assessment using standardized criteria, e.g., European Organization for Treatment of Cancer (EORTC) criteria and PET Response Criteria in Solid Tumors (PERCIST).</p><p><strong>New imaging methods and therapy: </strong>Fibroblast activation protein (FAP) is expressed at high concentrations in many sarcomas, often directly on the tumor cells themselves as well as on cancer-associated fibroblasts. FAP is therefore an attractive target for molecular imaging and therapy. <sup>68</sup>Ga-labeled FAP inhibitors (FAPIs) have shown higher uptake compared to <sup>18</sup>F‑FDG across all sarcoma subtypes, including those with low <sup>18</sup>F‑FDG avidity. FAPI-PET shows favorable tumor-background contrast and strong correlation with histopathological FAP expression. Prospective studies suggest that FAPI-PET may be superior to <sup>18</sup>F‑FDG-PET in certain histological subtypes and may identify candidates for FAP-targeted radioligand therapy (RLT). Early clinical experience with radioligands such as <sup>90</sup>Y‑FAPI-46 demonstrates safety, feasibility, and disease control under FAP-RLT in more than half of evaluable patients with advanced metastatic sarcoma.</p><p><strong>Outlook: </strong>Further prospective studies are needed to evaluate and establish the role of <sup>18</sup>F‑FDG and FAPI-PET in personalized treatment strategies and sarcoma management.</p>","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":" ","pages":"452-460"},"PeriodicalIF":0.6,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146215302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mitteilungen des Berufsverbandes der Deutschen Radiologie. 德国放射学专业协会。
IF 0.6
Radiologie (Heidelberg, Germany) Pub Date : 2026-06-01 DOI: 10.1007/s00117-026-01626-2
{"title":"Mitteilungen des Berufsverbandes der Deutschen Radiologie.","authors":"","doi":"10.1007/s00117-026-01626-2","DOIUrl":"https://doi.org/10.1007/s00117-026-01626-2","url":null,"abstract":"","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":"66 6","pages":"495-510"},"PeriodicalIF":0.6,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148145737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Possibilities for integrating artificial intelligence into the diagnostic process]. [将人工智能集成到诊断过程中的可能性]。
IF 0.6
Radiologie (Heidelberg, Germany) Pub Date : 2026-06-01 Epub Date: 2026-03-18 DOI: 10.1007/s00117-026-01588-5
Marc Kämmerer
{"title":"[Possibilities for integrating artificial intelligence into the diagnostic process].","authors":"Marc Kämmerer","doi":"10.1007/s00117-026-01588-5","DOIUrl":"10.1007/s00117-026-01588-5","url":null,"abstract":"<p><strong>Background: </strong>The changing working conditions in routine radiological reporting require the use of new methods, such as the implementation of artificial intelligence (AI) applications.</p><p><strong>Research question: </strong>What practical possibilities currently exist to integrate AI applications into existing imaging reporting processes?</p><p><strong>Material and methods: </strong>Assuming that the systems involved in the current reporting process, such as image management systems and various information systems, are to collaborate with AI applications, internationally recognized integration interfaces are required. The data exchanged also require standardized definitions to ensure interoperability across systems. Integration profiles as provided by Integrating the Healthcare Enterprise (IHE) offer a viable approach.</p><p><strong>Results: </strong>The IHE profiles, such as Scheduled Workflow.b (SWF.b) and AI Workflow for Imaging (AIW-I) enable the combination of traditional imaging processes from patient admission up to AI-supported image reporting. The AI Result Assessment (AIRA) profile ensures legally compliant usage of AI Results. The AIR profile defines interoperable AI result formats that can be distributed within a defined reporting context via the integrated reporting applications (IRA) profile. The Interactive Multimedia Report (IMR) profile supports the persistence of final reports. Additionally, various data format specifications are currently evolving toward the Fast Healthcare Interoperability Resources (FHIR) implementation guides for the Image Diagnostic Report and the EU Imaging Study Report.</p><p><strong>Discussion: </strong>The incorporation and use of AI in imaging processes are practically achievable using IHE profiles; however, integration based on structured data remains challenging and is currently reserved for larger institutions with the necessary IT resources.</p>","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":" ","pages":"471-480"},"PeriodicalIF":0.6,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147482746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Imaging of visceral, retroperitoneal, and pelvic soft-tissue sarcomas : Review]. 【内脏、腹膜后和盆腔软组织肉瘤的影像学:综述】。
IF 0.6
Radiologie (Heidelberg, Germany) Pub Date : 2026-06-01 Epub Date: 2026-04-21 DOI: 10.1007/s00117-026-01612-8
Aleksandar Milosevic, Michal-Kamil Chodyla, Rainer Hamacher, Johann Moritz Kaths, Johannes Haubold, Lale Umutlu
{"title":"[Imaging of visceral, retroperitoneal, and pelvic soft-tissue sarcomas : Review].","authors":"Aleksandar Milosevic, Michal-Kamil Chodyla, Rainer Hamacher, Johann Moritz Kaths, Johannes Haubold, Lale Umutlu","doi":"10.1007/s00117-026-01612-8","DOIUrl":"10.1007/s00117-026-01612-8","url":null,"abstract":"<p><strong>Background: </strong>Abdominal and retroperitoneal sarcomas are rare but prognostically relevant tumors that pose significant diagnostic challenges due to their size and proximity to critical anatomical structures. Cross-sectional imaging is crucial for detection, characterization, staging, and treatment planning.</p><p><strong>Objective: </strong>To present the current standards of cross-sectional imaging and to convey relevant aspects for radiological assessment based on established guidelines.</p><p><strong>Methods: </strong>Summary of the morphological characteristics, recommendations for imaging and resectability criteria based on current guidelines and published literature.</p><p><strong>Results: </strong>Magnetic resonance imaging (MRI) and computed tomography (CT) are indispensable for the assessment of abdominal and retroperitoneal sarcomas, especially with regard to organ and vessel relationships. MRI offers significant advantages over CT in the pelvis and for functional analysis. Typical patterns such as fat content, dedifferentiated areas, or infiltration support entity assessment and therapy planning.</p><p><strong>Conclusion: </strong>Standardized, guideline-based imaging is essential for diagnosis, treatment planning, and follow-up care and should be performed in interdisciplinary sarcoma centers.</p>","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":" ","pages":"446-451"},"PeriodicalIF":0.6,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147791586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Defining the danger zone for peroneal nerve safety in all-inside lateral meniscus repair: an MRI-based study. 确定全内外侧半月板修复中腓神经安全的危险区域:一项基于mri的研究。
IF 0.6
Radiologie (Heidelberg, Germany) Pub Date : 2026-05-05 DOI: 10.1007/s00117-026-01614-6
Berin Tuğtağ Demir, Simge Eşme, Ümmühan Yağmurkaya, Ali Köksal, Murat Demirel, Burak Bilecenoğlu
{"title":"Defining the danger zone for peroneal nerve safety in all-inside lateral meniscus repair: an MRI-based study.","authors":"Berin Tuğtağ Demir, Simge Eşme, Ümmühan Yağmurkaya, Ali Köksal, Murat Demirel, Burak Bilecenoğlu","doi":"10.1007/s00117-026-01614-6","DOIUrl":"https://doi.org/10.1007/s00117-026-01614-6","url":null,"abstract":"<p><strong>Background: </strong>The peroneal (fibular) nerve (PN) traverses the posterolateral aspect of the knee joint, placing it at risk during lateral meniscus (LM) repair, given its proximity to the popliteus tendon (PoT).</p><p><strong>Objective: </strong>This study aimed to evaluate the risk of PN injury and define a safe anchor penetration angle during all-inside LM repair.</p><p><strong>Materials and methods: </strong>A retrospective analysis was conducted using magnetic resonance imaging (MRI) scans of 327 individuals aged 18-60 years. The patellar tendon (PaT) and PoT widths were measured. The PN location relative to the PoT was determined. Distances from the PN to predefined medial and lateral reference lines across the PoT were calculated. The angular relationship between these lines and the transverse axis of the PaT was also analyzed for both anteromedial (AM) and anterolateral (AL) arthroscopic portals.</p><p><strong>Results: </strong>The PN-to-PoT distance was found to be comparable for both portals. However, the PN was significantly farther from the lateral reference line in the AM portal and from the medial reference line in the AL portal. The safe upper limit for anchor insertion was approximately 65° from the AM portal and 88° from the AL portal.</p><p><strong>Conclusion: </strong>Appropriate portal selection and anchor angle during all-inside LM repair can significantly reduce the risk of PN injury. The AL portal offers a broader safe insertion range and may therefore improve nerve protection.</p>","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147847331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Neuroradiology, pediatric radiology, or interventional radiology: Which path is right for me?] [神经放射学,儿科放射学,还是介入放射学:哪条路适合我?]]
IF 0.6
Radiologie (Heidelberg, Germany) Pub Date : 2026-05-01 Epub Date: 2026-03-16 DOI: 10.1007/s00117-026-01593-8
Andrea Jarre, Johanna Pape, Charlotte Wintergerst
{"title":"[Neuroradiology, pediatric radiology, or interventional radiology: Which path is right for me?]","authors":"Andrea Jarre, Johanna Pape, Charlotte Wintergerst","doi":"10.1007/s00117-026-01593-8","DOIUrl":"10.1007/s00117-026-01593-8","url":null,"abstract":"","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":" ","pages":"394-396"},"PeriodicalIF":0.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13095924/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147470506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Soft tissue sarcoma of the extremities-imaging, biopsy planning, and pitfalls in radiology]. 四肢软组织肉瘤——影像学、活检计划和放射学陷阱。
IF 0.6
Radiologie (Heidelberg, Germany) Pub Date : 2026-05-01 Epub Date: 2026-03-25 DOI: 10.1007/s00117-026-01605-7
Timo Leichenich, Oliver Sedlaczek, Jonas Fehlinger, Sam Sedaghat, Burkhard Lehner, Andreas Geisbüsch, Christoph Rehnitz
{"title":"[Soft tissue sarcoma of the extremities-imaging, biopsy planning, and pitfalls in radiology].","authors":"Timo Leichenich, Oliver Sedlaczek, Jonas Fehlinger, Sam Sedaghat, Burkhard Lehner, Andreas Geisbüsch, Christoph Rehnitz","doi":"10.1007/s00117-026-01605-7","DOIUrl":"10.1007/s00117-026-01605-7","url":null,"abstract":"<p><strong>Background: </strong>Radiology is integral to the multimodal diagnostic and treatment pathway of extremity soft tissue sarcomas in DGK-certified sarcoma centers (DGK: Deutsche Krebsgesellschaft, German Cancer Society), working in close interdisciplinary collaboration with sarcoma surgery, pathology, radiation oncology, and medical oncology.</p><p><strong>Guideline-based imaging and triage: </strong>Treatment decisions rely on guideline- and recommendation-based imaging and histological confirmation by biopsy. When clinical warning signs (red flags) are present, radiological imaging is essential for triage and early referral to a sarcoma center. For local staging, magnetic resonance imaging (MRI) is the modality of choice. It provides crucial information for diagnosis, prognosis, and treatment within the sarcoma board and serves as the basis for adequate biopsy planning.</p><p><strong>Morphological and technical pitfalls: </strong>Diagnostic pitfalls arise from overlapping MRI appearances, particularly within the lipomatous spectrum and in lesions with myxoid and cystic patterns. A further focus is on avoidable procedural biopsy errors, inadequate targeting, and an inadequate biopsy tract that is not amenable to en bloc resection or that contaminates additional compartments/joints or neurovascular structures.</p><p><strong>Conclusion: </strong>The article outlines a risk-adapted diagnostic approach and provides practice-oriented principles for biopsy planning. It highlights typical problem MRI constellations to avoid misdiagnosis and underestimation of malignancy (grading), ultimately establishing optimal prerequisites for therapy.</p>","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":" ","pages":"363-379"},"PeriodicalIF":0.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147517339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Rare cause of bacterial peritonitis]. 【细菌性腹膜炎的罕见病因】。
IF 0.6
Radiologie (Heidelberg, Germany) Pub Date : 2026-05-01 Epub Date: 2026-01-08 DOI: 10.1007/s00117-025-01551-w
Christopher Kloth, Thomas Breining, Annika Beck, Axel John, Meinrad Beer, Daniel Vogele
{"title":"[Rare cause of bacterial peritonitis].","authors":"Christopher Kloth, Thomas Breining, Annika Beck, Axel John, Meinrad Beer, Daniel Vogele","doi":"10.1007/s00117-025-01551-w","DOIUrl":"10.1007/s00117-025-01551-w","url":null,"abstract":"","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":" ","pages":"390-393"},"PeriodicalIF":0.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13095960/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145936752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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