Progress in rehabilitation medicine最新文献

{"title":"Characteristics of Systematic Errors in the Two-step Test for Assessing Locomotive Syndrome among Young and Older Adults.","authors":"Yohei Sawaya, Tamaki Hirose, Takahiro Shiba, Lu Yin, Ryo Sato, Shuntaro Tsuji, Tomohiko Urano","doi":"10.2490/prm.20250029","DOIUrl":"10.2490/prm.20250029","url":null,"abstract":"<p><strong>Objectives: </strong>The two-step test is a key component of the locomotive syndrome risk test, but few studies have examined its systematic errors, particularly in young adults. We investigated errors in young and older adults and identified the threshold for measurement errors.</p><p><strong>Methods: </strong>This cross-sectional study included 95 university students and 40 older adults and was conducted between April 2023 and March 2025. Participants performed the two-step test twice within a 7-day interval. Bland-Altman analysis assessed fixed and proportional bias for the two-step test length (length) and value (length normalized to height), and minimal detectable change (MDC) and limit of agreement (LOA) were calculated.</p><p><strong>Results: </strong>In young adults, the two-step test length was 279.2 ± 24.4 cm (difference: 8.4 ± 12.3 cm) and the two-step test value was 1.70 ± 0.11 cm/height (difference: 0.05 ± 0.07 cm/height); in older adults, these respective results were 140.7 ± 34.3 cm (0.0 ± 13.7 cm) and 0.89 ± 0.21 cm/height (0.00 ± 0.09 cm/height). In young adults, fixed bias was identified for length and value, whereas no systematic errors were detected in older adults. LOA ranged from -11.5 to 28.2 cm for length and from -0.07 to 0.17 cm/height for value in young adults. The MDC in older adults was 26.9 cm for length and 0.17 cm/height for value.</p><p><strong>Conclusions: </strong>In young adults, the result for the two-step test tended to increase during retesting, requiring caution in interpreting intervention effects. An increase at retesting of more than 0.17 cm/height for the test value or 25-30 cm for test length may be a clinically useful indicator, exceeding the smallest detectable change for both young and older adults based on LOA and MDC.</p>","PeriodicalId":74584,"journal":{"name":"Progress in rehabilitation medicine","volume":"10 ","pages":"20250029"},"PeriodicalIF":1.5,"publicationDate":"2025-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12547279/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145380150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inferential Statistics for Electrophysiological Analysis of Paretic Upper Limb-sensory Deficits and Muscle Imbalance in Patients with Acute Stroke.","authors":"Kakeru Mizumura, Kohei Koizumi, Tsuyoshi Kouda, Tetsuya Okihara, Hajime Maruyama, Hidetoshi Takahashi, Toyohiro Hamaguchi","doi":"10.2490/prm.20250028","DOIUrl":"10.2490/prm.20250028","url":null,"abstract":"<p><strong>Objectives: </strong>The prevalence of somatosensory dysfunction after stroke exceeds 50%, and its severity is negatively correlated with upper limb function and the ability to perform self-care tasks. This study objectively assessed somatosensory deficits in the acute post-stroke phase and characterized muscle-output imbalance across severity levels.</p><p><strong>Methods: </strong>This prospective observational pilot study was conducted at Saitama Medical University International Medical Center between June 2021 and July 2023. Forty-one patients (age 66 ± 10 years) with acute stroke were assessed for somatosensory deficits and muscle-output imbalance. The severity of somatosensory disturbance was grouped according to short-latency sensory evoked potentials (SSEP), and the change in the muscle co-contraction index (CCI) from surface electromyography (sEMG) was compared at two points within 1 week. The sEMG data for each SSEP group were replicated 1000 times using the bootstrap method.</p><p><strong>Results: </strong>An interaction was observed across all movement directions. In the comparison analysis, significant changes were observed in the normal group except for elbow flexion on the non-paretic side. In the delayed group, only wrist flexion on the non-paretic side changed more than one standard deviation. The changes observed in the severe SSEP group were inferred as fluctuations in CCI, even in the early stages of stroke onset.</p><p><strong>Conclusions: </strong>This study showed that changes in CCI of the upper extremity vary with the severity of somatosensory disturbance in patients with acute stroke and that muscle-output imbalance can change within 1 week of onset of acute stroke.</p>","PeriodicalId":74584,"journal":{"name":"Progress in rehabilitation medicine","volume":"10 ","pages":"20250028"},"PeriodicalIF":1.5,"publicationDate":"2025-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12546994/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145380100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantitative Gait Assessment before and after Limb Lengthening in a Patient with Achondroplasia: A Case Report.","authors":"Yusuke Yasutani, Hiroki Fujita, Takahito Inoue, Atsushi Teramoto","doi":"10.2490/prm.20250027","DOIUrl":"10.2490/prm.20250027","url":null,"abstract":"<p><strong>Background: </strong>Achondroplasia, a common skeletal dysplasia, results from a gain-of-function mutation in the fibroblast growth factor receptor 3 gene. It is characterized by short-limbed dwarfism and is frequently associated with skeletal deformities, including genu varum and tibial bowing, which often impair gait and limit daily function. Although limb lengthening with an external fixator is a widely utilized intervention, quantitative evaluations of its effectiveness remain limited.</p><p><strong>Case: </strong>A 10-year-old boy with achondroplasia presented with progressive lower limb deformity and gait disturbance. Preoperative assessments revealed pronounced genu varum, tibial bowing, and mechanical axis deviation. Bilateral tibiofibular lengthening using the Taylor Spatial Frame was performed, achieving a 6-cm increase in limb length. The external fixator was removed 1 year postoperatively. Gait rehabilitation commenced 4 months postoperatively, with full independent ambulation achieved by 6 months. Quantitative assessments using the 6-minute walk test (6MWT) and three-dimensional gait analysis (3DGA) demonstrated improvements in walking distance, cadence, and a reduction in the Physiological Cost Index (0.29 to 0.1). Preoperative 3DGA revealed significant gait deviations, which improved postoperatively, including a 9.5° reduction in the Gait Profile Score.</p><p><strong>Discussion: </strong>Moment analysis indicated reductions in knee flexion and varus moments, suggesting improved gait efficiency. These findings suggest that limb lengthening enhances both limb alignment and functional gait performance. The integration of 3DGA and 6MWT with conventional radiographic evaluation offers a comprehensive assessment of treatment outcomes, reinforcing the effectiveness of surgical intervention and rehabilitation in patients with achondroplasia.</p>","PeriodicalId":74584,"journal":{"name":"Progress in rehabilitation medicine","volume":"10 ","pages":"20250027"},"PeriodicalIF":1.5,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12520822/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145304791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Metaverse Paradox: Insights from Secondary Analysis of Metaverse Health Survey and Future Strategies.","authors":"Ryo Momosaki, Kazuma Tora, Yuka Shirai, Yoko Hasegawa, Kenta Ushida, Ryota Sakamoto, Hiroki Funao","doi":"10.2490/prm.20250026","DOIUrl":"10.2490/prm.20250026","url":null,"abstract":"","PeriodicalId":74584,"journal":{"name":"Progress in rehabilitation medicine","volume":"10 ","pages":"20250026"},"PeriodicalIF":1.5,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12504454/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145260001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Longitudinal Study of Quality of Life in Individuals with Lower Limb Amputation.","authors":"Takashi Nakamura, Yoshiko Tobimatsu","doi":"10.2490/prm.20250025","DOIUrl":"10.2490/prm.20250025","url":null,"abstract":"<p><strong>Objectives: </strong>Assessment of quality of life (QOL) is essential in evaluating rehabilitation outcomes for individuals with lower limb amputation (LLA). However, there are few longitudinal studies of QOL over extended periods. This study reports the findings of a third QOL survey conducted in 2021 using the Japanese version of the Prosthetic Evaluation Questionnaire (PEQ-J), following previous surveys in 2003 and 2011.</p><p><strong>Methods: </strong>The survey targeted 254 individuals with LLA who had received prosthetic limbs from our center. Questionnaires were mailed, and responses were analyzed using the PEQ-J. Results were compared with those from previous surveys. The Mann-Whitney U test was used to assess statistical significance.</p><p><strong>Results: </strong>Responses were received from 129 participants (response rate: 51%): 101 males and 28 females, with a mean age of 62.8 ± 14.8 years. Causes of amputation were trauma (n=83), disease (n=44), and others (n=2). The present survey had more older participants than the previous surveys. Fifty-seven individuals responded to both the 2011 and 2021 surveys. The most notable changes were observed in psychological domains. Sex-based differences in \"Perceived Response\" observed in 2011 were not present in 2021. Moreover, differences in \"Frustration\" and \"Social Burden\" related to time since amputation were no longer observed.</p><p><strong>Conclusions: </strong>Our findings suggest that psychological adaptation may evolve over time, reducing disparities previously associated with sex and amputation duration. Advanced prosthetics and the Tokyo 2020 Paralympic Games may have effected improvements in QOL in individuals with LLA.</p>","PeriodicalId":74584,"journal":{"name":"Progress in rehabilitation medicine","volume":"10 ","pages":"20250025"},"PeriodicalIF":1.5,"publicationDate":"2025-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12484563/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145214757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trends in the Use of a Financial Incentive for Device-assisted Rehabilitation in Japan: A Descriptive Analysis Using National Health Insurance Data.","authors":"Daisuke Kubo, Takuya Hirose, Yushi Asaoka","doi":"10.2490/prm.20250024","DOIUrl":"10.2490/prm.20250024","url":null,"abstract":"","PeriodicalId":74584,"journal":{"name":"Progress in rehabilitation medicine","volume":"10 ","pages":"20250024"},"PeriodicalIF":1.5,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12460032/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145187560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between Frailty Assessed Using the Kihon Checklist and Rheumatoid Arthritis.","authors":"Takeshi Mochizuki, Koichiro Yano, Katsunori Ikari, Ken Okazaki","doi":"10.2490/prm.20250023","DOIUrl":"10.2490/prm.20250023","url":null,"abstract":"<p><strong>Objectives: </strong>This study investigated the relationship between frailty as assessed using the Kihon checklist (KCL) and rheumatoid arthritis (RA) status.</p><p><strong>Methods: </strong>In total, 626 consecutive patients with RA were enrolled in this cross-sectional study. We examined the patients' KCL scores, characteristics, and clinical data. The patients were grouped according to their KCL scores as follows: robust (scores of 0-3), pre-frailty (scores of 4-7), and frailty (scores ≥8).</p><p><strong>Results: </strong>Frailty, pre-frailty, and robust groups accounted for 36.9%, 30.5%, and 32.6% of the patients, respectively. Significant factors comparing frailty and robust groups were age (P < 0.001), Health Assessment Questionnaire Disability Index (HAQ-DI) (P < 0.001), and habitual exercise (P = 0.004). Significant factors comparing the pre-frailty and robust groups were age (P < 0.001) and HAQ-DI (P = 0.041).</p><p><strong>Conclusions: </strong>In patients with RA, HAQ-DI and exercise should be managed to prevent frailty and avoid the need for long-term care. Our results will help identify those patients who can most benefit from aggressive management of RA.</p>","PeriodicalId":74584,"journal":{"name":"Progress in rehabilitation medicine","volume":"10 ","pages":"20250023"},"PeriodicalIF":1.5,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12442108/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145088533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pharmacotherapy in Geriatric Rehabilitation: A Paradigm Shift from Disease Management to Functional Enhancement.","authors":"Yoshihiro Yoshimura, Ayaka Matsumoto","doi":"10.2490/prm.20250022","DOIUrl":"10.2490/prm.20250022","url":null,"abstract":"","PeriodicalId":74584,"journal":{"name":"Progress in rehabilitation medicine","volume":"10 ","pages":"20250022"},"PeriodicalIF":1.5,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12442107/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145088426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effects of Short-term Intensive Inpatient Rehabilitation on Motor, Non-motor, and Neuropsychological Functions in Parkinson's Disease.","authors":"Kana Sakuma, Keiji Hashimoto, Masahiro Konishi, Ryuta Kinno, Nobuyuki Kawate, Hiroo Ichikawa","doi":"10.2490/prm.20250021","DOIUrl":"10.2490/prm.20250021","url":null,"abstract":"<p><strong>Objectives: </strong>In previous studies, intensive rehabilitation for patients with Parkinson's disease (PD) has been implemented in both outpatient and inpatient settings, with varying durations across studies. Among these, most inpatient intensive rehabilitation programs are conducted for 1 month, with few reports evaluating detailed changes in neuropsychological functions. In this study, we investigated the effect of a short-term intensive inpatient rehabilitation program lasting 2 or 3 weeks on motor and non-motor symptoms, motor ability, and neuropsychological functions in hospitalized patients with PD.</p><p><strong>Methods: </strong>We enrolled 15 patients with PD (7 men, 8 women; mean age, 75.1±6.5 years; Hoehn and Yahr stages III/IV, 12/3). The rehabilitation program included physical, occupational, and speech-language therapies and was implemented daily for 2 or 3 weeks. Motor and non-motor symptoms as well as motor abilities were assessed using the Movement Disorders Society Unified Parkinson's Disease Rating Scale, Functional Independence Measure, Parkinson's Disease Questionnaire-39, and other assessments. Neuropsychological functions were evaluated using Japanese versions of the Mini-Mental State Examination and Frontal Assessment Battery and using the CogEvo (computerized cognitive function evaluation) tool. Scores were compared before and after intervention.</p><p><strong>Results: </strong>This short-term inpatient rehabilitation therapy significantly improved motor and non-motor symptoms, motor abilities, reality orientation as assessed by CogEvo, and the overall quality of life.</p><p><strong>Conclusions: </strong>The results of this study suggest that short-term intensive rehabilitation in patients with PD may achieve favorable outcomes even within a limited timeframe. Further discussion of the appropriate duration of inpatient rehabilitation for patients with PD is warranted.</p>","PeriodicalId":74584,"journal":{"name":"Progress in rehabilitation medicine","volume":"10 ","pages":"20250021"},"PeriodicalIF":1.5,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12417591/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145042561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Cartilage Degeneration Using MRI T1ρ Mapping after Locomotion Training in Patients with Early Knee Osteoarthritis.","authors":"Yuji Arai, Kazuteru Ryu, Shuji Nakagawa, Koichi Idei, Atsuo Inoue, Kenji Takahashi","doi":"10.2490/prm.20250020","DOIUrl":"10.2490/prm.20250020","url":null,"abstract":"<p><strong>Objectives: </strong>: This study aimed to assess the qualitative effects of locomotion training (LT) on articular cartilage using magnetic resonance imaging T1ρ mapping.</p><p><strong>Methods: </strong>: Fifteen patients with early knee osteoarthritis participated in the study. They performed a series of exercises, including one-leg stands, squats, heel raises, and front lunges, on a daily basis for 12 weeks. Knee joint function and physical performance were evaluated before and 3 months after completing the LT program. Additionally, a questionnaire was administered to assess patient-reported outcomes. The quality of articular cartilage was evaluated through magnetic resonance imaging using T1ρ mapping. T1ρ values were quantified on sagittal planes with ten regions of interest.</p><p><strong>Results: </strong>: Regarding physical function, the time required for one-leg stands was significantly increased following LT, and the right functional reach test and the 30-s chair stand test showed improvement. T1ρ values were significantly reduced at 0° relative to the anatomical axis of the femur, whereas other regions of interest showed no significant change after LT.</p><p><strong>Conclusions: </strong>: LT significantly improved muscle strength and balance in patients with early knee osteoarthritis. LT also improved the T1ρ values of articular cartilage at 0° relative to the anatomical axis of the femur. This change may reflect that LT mitigates cartilage degeneration following the application of moderate mechanical stress to the loading region. We propose that LT represents a safe and effective exercise therapy for early knee osteoarthritis, with the potential to improve both motor function and articular cartilage quality.</p>","PeriodicalId":74584,"journal":{"name":"Progress in rehabilitation medicine","volume":"10 ","pages":"20250020"},"PeriodicalIF":1.5,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12408120/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145016907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}