Physical therapy research最新文献

{"title":"The Assessment and Response of Rehabilitation Professionals to Sudden Deterioration in Symptoms: An Analysis of the National Database in Japan.","authors":"Naoki Sasanuma, Keiko Takahashi, Akiyo Eguchi, Shinya Yamauchi, Yuki Uchiyama, Kazuhisa Domen","doi":"10.1298/ptr.E10272","DOIUrl":"https://doi.org/10.1298/ptr.E10272","url":null,"abstract":"<p><strong>Objective: </strong>There are few analyses of the current status of and responses to acute deteriorations encountered by physiotherapists, occupational therapists, and speech-language pathologists (rehabilitation professions [RPs]). The purpose of this study was to analyze the responses of RPs to acute deterioration in patients using the functional resonance analysis method (FRAM) based on the descriptions in \"the Medical Accident Database\".</p><p><strong>Methods: </strong>Subjects were 413 cases with medical incidents reported by RPs to the database from 2012 to 2021. Life-threatening cases with changes in consciousness, circulation, and respiration were selected. Descriptions regarding findings assessed by RPs and support team, and requests for assistance were extracted. We also attempted to construct appropriate respond in RPs by using the FRAM.</p><p><strong>Results: </strong>Thirty-nine cases of acute deterioration were included in the analysis, and descriptions by RPs of consciousness (35 cases), circulation (18 cases), and respiration (36 cases) were identified. Blood pressure and percutaneous oxygen saturation measurement were frequently presented in the assessment by RPs, whereas the support team assessed cardiac arrest and respiratory arrest in high frequency. The FRAM analysis indicated that appropriate and rapid post-response by RPs requires patient information in prior, appropriate assessment and integration/interpretation.</p><p><strong>Conclusion: </strong>We attempted to identify problems analyzing the response by RPs to acute deterioration using the database and construct an appropriate response model. It resulted that RPs need to obtain patient information in advance and integrate/interpret it appropriately based on accurate assessment of conscious, circulation and respiration for rapid response. A model including integration/interpretation for appropriate post-response by RPs was constructed using the FRAM.</p>","PeriodicalId":74445,"journal":{"name":"Physical therapy research","volume":"27 1","pages":"21-34"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11057387/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140869182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Isometric Quadriceps Muscle Exercise with Visual and Auditory Feedback at 1 Year after Total Knee Arthroplasty.","authors":"Yasutaka Kondo, Yoshihiro Yoshida, Takashi Iioka, Hideki Kataoka, Junya Sakamoto, Yuichiro Honda, Atsushi Nawata, Minoru Okita","doi":"10.1298/ptr.E10260","DOIUrl":"https://doi.org/10.1298/ptr.E10260","url":null,"abstract":"<p><strong>Objective: </strong>To examine the effect of isometric quadriceps exercises with visual and auditory feedback after total knee arthroplasty (TKA).</p><p><strong>Methods: </strong>The sample included 41 patients from our previous study who could be followed up for 1 year after TKA. Patients in the intervention group performed isometric quadriceps exercises with visual and auditory feedback using the quadriceps training machine from the 2nd to the 14th day after TKA, whereas those in the control group underwent standard postoperative rehabilitation (without visual or auditory feedback during isometric quadriceps exercises) in the hospital. Patients were evaluated for pain intensity, timed up and go test (TUG) score, 10-m gait speed, 6-minute walking distance (6MWD), and the Western Ontario and McMaster University Osteoarthritis Index (WOMAC) score 1 year after TKA. Additionally, exercise habits and responses to the International Physical Activity Questionnaire (IPAQ) were investigated.</p><p><strong>Results: </strong>Pain intensity was significantly lower in the intervention group than in the control group. Greater improvements in the TUG test scores, 10-m gait speed, 6MWD, and WOMAC scores were observed in the intervention group. Walking activity, as recorded by the IPAQ, and the proportion of patients with exercise habits were significantly higher in the intervention group than in the control group.</p><p><strong>Conclusions: </strong>These results suggest that performing isometric quadriceps exercise with visual and auditory feedback using the quadriceps training machine has good effects, such as pain reduction, physical function improvement, exercise tolerance, and increased physical activity at 1 year after TKA.</p>","PeriodicalId":74445,"journal":{"name":"Physical therapy research","volume":"27 1","pages":"6-13"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11057392/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140856861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Clinical Prediction Rule for Predicting the Health-related Quality of Life after 5 Months in Patients with Knee Osteoarthritis Undergoing Conservative Treatment.","authors":"Shunsuke Yamashina, Tetsuya Amano, Shigeharu Tanaka, Yu Inoue, Ryo Tanaka","doi":"10.1298/ptr.E10296","DOIUrl":"10.1298/ptr.E10296","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to derive a clinical prediction rule (CPR) that can predict changes in health-related quality of life at 5 months for patients with knee osteoarthritis (KOA) undergoing conservative treatment.</p><p><strong>Methods: </strong>Patients with KOA receiving physical therapy and exercise therapy at an outpatient clinic were included in this study. The basic characteristics, medical information, and motor function test results were recorded at baseline. The primary outcome measure was the change in the Japan Knee Osteoarthritis Measure (JKOM) 5 months after the baseline measurement. A decision tree analysis was performed with the basic characteristics, medical information, and the motor function test results as the independent variables and the changes in the JKOM after 5 months (≥8 in the improved groups) as the dependent variable.</p><p><strong>Results: </strong>Analyzed data from 87 patients. The variables included the visual analog scale score, bilateral KOA, 5-m walk test, JKOM, and body mass index. Six CPRs were obtained from the terminal nodes. Accuracy validation of the model for the entire decision tree revealed an area under the receiver operating characteristic curve of 0.87 (validation data: 0.83), a positive likelihood ratio of 2.6, and a negative likelihood ratio of 0.1.</p><p><strong>Conclusion: </strong>This CPR is an inspection characteristic that can exclude the possibility of the occurrence of an event based on a negative result. However, since the results of this study represent the first process of utilizing the CPR in actual clinical practice, its application should be kept in mind.</p>","PeriodicalId":74445,"journal":{"name":"Physical therapy research","volume":"27 3","pages":"158-165"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11756558/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143048963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current Status of the Cognitive Impairment in Chronic Kidney Disease.","authors":"Yuhei Otobe","doi":"10.1298/ptr.R0033","DOIUrl":"10.1298/ptr.R0033","url":null,"abstract":"<p><p>Chronic kidney disease (CKD) is a recognized risk factor for cognitive impairment and dementia. Unfortunately, the number of patients with both CKD and dementia has been steadily increasing with the aging patient population. Therapeutic management and clinical decision-making become more challenging in patients with dementia who often experience worsening prognoses, highlighting the urgency of developing effective countermeasures. This review explores available research on the epidemiology, contributing factors, mechanisms, and outcomes of cognitive impairment and dementia in patients with CKD while outlining the impact of exercise therapy on cognitive function.</p>","PeriodicalId":74445,"journal":{"name":"Physical therapy research","volume":"27 3","pages":"115-120"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11756563/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143048966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perioperative Rehabilitation in Collaboration with the Department of Occupational Medicine for Patients with Cholangiocarcinoma: A Case Report.","authors":"Hiroaki Teramatsu, Akiko Hachisuka, Masako Nagata, Shiro Kohi, Manabu Hamada, Satoshi Kuhara, Akio Takemoto, Hideaki Itoh, Satoru Saeki","doi":"10.1298/ptr.E10275","DOIUrl":"https://doi.org/10.1298/ptr.E10275","url":null,"abstract":"<p><strong>Introduction: </strong>Although the number of cancer survivors has increased, the role of physical therapy in return to work (RTW) for employed patients with cancer remains unclear.</p><p><strong>Case presentation: </strong>The patient is a 50-year-old man diagnosed with cholangiocarcinoma who worked as a liquefied petroleum gas station filler. He started perioperative rehabilitation and underwent pancreaticoduodenectomy for cholangiocarcinoma. He developed a postoperative pancreatic fistula, which improved with conservative treatment over 40 days. Although he achieved independence regarding day-to-day activities, his physical condition and workability worsened, as his skeletal muscle index decreased from 8.7 to 7.7, 6-min walk distance from 518 to 460 m, and work ability index (WAI) from 37 to 20 points. His physical therapist was concerned about his RTW and recommended that he receive RTW support from the Department of Occupational Medicine (DOM). The DOM employed a team approach for the RTW strategy, and the primary physician, occupational physician, and company collaborated to support the patient. After the outpatient treatment protocol and RTW support plans were formulated, the patient was discharged. The physical therapist reported declining physical performance and WAI at the DOM's multidisciplinary conference. After consulting with multiple professionals, the team recommended work resumption in stages: part-time for three months and full-time for four months after surgery while undergoing oral adjuvant chemotherapy. The WAI improved to 35 points after RTW.</p><p><strong>Conclusion: </strong>This case report suggests that physical therapists are vital in providing continuous patient support, from perioperative rehabilitation to DOM intervention, to build physical strength for return to work.</p>","PeriodicalId":74445,"journal":{"name":"Physical therapy research","volume":"27 2","pages":"108-114"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11382788/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142302839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Review of the Design of Multimedia Patient Educational Materials in Low Back Pain Research.","authors":"Garett VAN Oirschot, Cailbhe Doherty","doi":"10.1298/ptr.R0032","DOIUrl":"https://doi.org/10.1298/ptr.R0032","url":null,"abstract":"<p><p>Low back pain guidelines recommend patient education as a component of management. Multimedia education materials to provide patient education are increasingly being used not only due to the convenience of digital services but also because this is an efficient way to deliver educational information to under-resourced or rural/remote regions without optimal healthcare services. To maximize the knowledge transfer of research findings and low back pain guidelines, scientifically backed information must evolve beyond journal prints, bland government websites, and the basic web design of budget-constrained advocacy groups. Materials must instead be engaging for the public and compete with the various sources of low back pain misinformation, which can appear attractive and eye-catching while being conveniently accessed. We discuss a data subset from a larger musculoskeletal healthcare review to highlight the educational materials used in low back pain randomized controlled trials found in the literature. While there is no standard way to appraise the effectiveness of such educational materials, potential options are discussed. Future research is needed to determine whether knowledge is being transferred and whether this is the avenue to improving patient outcomes.</p>","PeriodicalId":74445,"journal":{"name":"Physical therapy research","volume":"27 2","pages":"58-66"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11382792/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142302894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the Impact of Sports Participation on Social Capital and Health-related Factors in Individuals with Spinal Cord Injury: A Cross-sectional Study.","authors":"Kazuki Kaneda, Noriaki Maeda, Takumi Nagao, Ayano Ishida, Tsubasa Tashiro, Makoto Komiya, Yukio Urabe","doi":"10.1298/ptr.E10295","DOIUrl":"10.1298/ptr.E10295","url":null,"abstract":"<p><strong>Objective: </strong>This study examined the impact of sports participation on the health status of individuals with spinal cord injuries (SCI), with emphasis on the role of health-related social capital (HRSC).</p><p><strong>Methods: </strong>This study included 65 individuals with SCI (42 who participated in sports and 23 who did not). The following information was obtained from the participants through an online questionnaire: their basic information, information regarding activities of daily life independence, physical activity, mental health, lifestyle, insomnia, and social capital. We compared the outcomes between participants with and without sports participation and examined their correlations. Multiple regression analysis with forced entry was performed to determine the association between HRSC and health outcomes.</p><p><strong>Results: </strong>Physical activity, mental health, and HRSC were significantly higher in individuals with SCI who participated in sports (p <0.01 or p <0.05) than in individuals with SCI who did not participate in sports. The HRSC of individuals with SCI with sports participation showed a significant positive correlation with lifestyle and a significant negative correlation with insomnia score (p <0.05). Multiple regression analysis revealed that higher HRSC was associated with lifestyle in individuals with SCI who participated in sports (p <0.05) compared with individuals with SCI who did not participate in sports.</p><p><strong>Conclusion: </strong>The study findings underscore the potential benefits of sports participation in individuals with SCI, including increased physical activity and development of HRSC. However, it is essential to consider the implications of sports involvement on the psychological well-being of individuals with disabilities and provide appropriate support.</p>","PeriodicalId":74445,"journal":{"name":"Physical therapy research","volume":"27 3","pages":"128-135"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11756564/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143048937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Smile Training on Gait Disturbance in Parkinson's Disease Patient with Neuropsychiatric Symptoms: A Single Case Design.","authors":"Yumeka Harada, Tatsuya Iwabe, Keisuke Ota, Shinsuke Hamada, Fumio Moriwaka","doi":"10.1298/ptr.E10290","DOIUrl":"10.1298/ptr.E10290","url":null,"abstract":"<p><strong>Objective: </strong>To verify the efficacy of smile training in improving gait disturbances in patients with Parkinson's disease (PD) exhibiting neuropsychiatric symptoms.</p><p><strong>Methods: </strong>A single-case BAB design with three intervention periods (B1, A1, and B2) was used. During periods B1 and B2, 10 min of smile training (facial muscles training and positive thinking training) was performed before the usual exercise therapy. During the A1 period, the participant received only the usual exercise therapy. During the intervention period, the Timed Up and Go test (TUG) was performed daily in both directions. Tau-U was calculated to determine the effect size of the TUG test time and the number of steps taken during each period. Movement Disorder Society-Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Part III, Hospital Anxiety and Depression Scale (HADS), 10-meter walk at maximum speed, Berg Balance Scale, and Characterizing Freezing of Gait Questionnaire (C-FOGQ) were administered on the day before the start of the intervention and the last day of each period.</p><p><strong>Results: </strong>Comparisons of A1 to B2, TUG time, and the number of steps taken on both turns revealed large reductions (Tau-U ≥0.74, p <0.01). The 10-meter walk speed and MDS-UPDRS Part III bradykinesia scores improved, whereas the frequency of gait freezing on the C-FOGQ remained unchanged. The HADS scores did not show significant changes; however, the participant made more positive statements in his reflections.</p><p><strong>Conclusion: </strong>Smile training may be an effective intervention for improving gait and other motor symptoms in patients with PD.</p>","PeriodicalId":74445,"journal":{"name":"Physical therapy research","volume":"27 3","pages":"173-179"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11756565/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143048969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and Validation of a Decision Tree Analysis Model for Predicting Home Discharge in a Convalescent Ward: A Single Institution Study.","authors":"Dai Nakaizumi, Shingo Miyata, Keita Uchiyama, Ikki Takahashi","doi":"10.1298/ptr.E10267","DOIUrl":"https://doi.org/10.1298/ptr.E10267","url":null,"abstract":"<p><strong>Objectives: </strong>Accurately predicting the likelihood of inpatients' home discharge in a convalescent ward is crucial for assisting patients and families in decision-making. While logistic regression analysis has been commonly used, its complexity limits practicality in clinical settings. We focused on decision tree analysis, which is visually straightforward. This study aimed to develop and validate the accuracy of a prediction model for home discharge for inpatients in a convalescent ward using a decision tree analysis.</p><p><strong>Methods: </strong>The cohort consisted of 651 patients admitted to our convalescent ward from 2018 to 2020. We collected data from medical records, including disease classification, sex, age, duration of acute hospitalization, discharge destination (home or nonhome), and Functional Independence Measure (FIM) subitems at admission. We divided the cohort data into training and validation sets and developed a prediction model using decision tree analysis with discharge destination as the target and other variables as predictors. The model's accuracy was validated using the validation data set.</p><p><strong>Results: </strong>The decision tree model identified FIM grooming as the first single discriminator of home discharge, diverging at four points and identifying subsequent branching for the duration of acute hospitalization. The model's accuracy was 86.7%, with a sensitivity of 0.96, specificity of 0.52, positive predictive accuracy of 0.88, and negative predictive accuracy of 0.80. The area under the receiver operating characteristic curve was 0.75.</p><p><strong>Conclusion: </strong>The predictive model demonstrated more than moderate predictive accuracy, suggesting its utility in clinical practice. Grooming emerged as a variable with the highest explanatory power for determining home discharge.</p>","PeriodicalId":74445,"journal":{"name":"Physical therapy research","volume":"27 1","pages":"14-20"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11057389/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140853796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association Between Early Mobilization and Postoperative Pneumonia Following Robot-assisted Minimally Invasive Esophagectomy in Patients with Thoracic Esophageal Squamous Cell Carcinoma.","authors":"Yasuaki Nozawa, Kazuhiro Harada, Kazuhiro Noma, Yoshimi Katayama, Masanori Hamada, Toshifumi Ozaki","doi":"10.1298/ptr.E10293","DOIUrl":"10.1298/ptr.E10293","url":null,"abstract":"<p><strong>Objective: </strong>The objective of this study was to confirm that early mobilization (EM) could reduce pneumonia in patients undergoing robot-assisted minimally invasive esophagectomy (RAMIE) for thoracic esophageal squamous cell carcinoma (TESCC).</p><p><strong>Methods: </strong>Postoperative pneumonia was defined as physician-diagnosed pneumonia using the Esophagectomy Complications Consensus Group definition of pneumonia with a Clavien-Dindo classification grade II-V on postoperative day (POD) 3-5. EM was defined as achieving an ICU Mobility Scale (IMS) ≥7 by POD 2. Patients were divided into EM (n = 36) and non-EM (n = 35) groups. Barriers to EM included pain, orthostatic intolerance (OI), and orthostatic hypotension.</p><p><strong>Results: </strong>The overall incidence of postoperative pneumonia was 12.7%, with a significant difference between the EM (2.8%) and non-EM (22.9%) groups (P = 0.014). The odds ratio was 0.098 in the EM group compared to the non-EM group. A significant difference was found between the two groups in terms of the barriers to EM at POD 2 only for OI, with a higher incidence in the non-EM group. Multivariate logistic regression analysis showed that patients with OI were more likely to be unable to achieve EM than those without OI (odds ratio, 7.030; P = 0.006).</p><p><strong>Conclusion: </strong>EM within POD 2 may reduce the incidence of postoperative pneumonia in patients undergoing RAMIE for TESCC. Furthermore, it was suggested that OI can have a negative impact on the EM after RAMIE.</p>","PeriodicalId":74445,"journal":{"name":"Physical therapy research","volume":"27 3","pages":"121-127"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11756562/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143048964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}