Oxygen (Basel, Switzerland)最新文献_第2页

Study of the Total Phenolic Content, Total Antioxidant Activity and In Vitro Digestibility of Novel Wheat Crackers Enriched with Cereal, Legume and Agricultural By-Product Flours 富含谷类、豆类和农副产品面粉的新型小麦脆片的总酚含量、总抗氧化活性和体外消化性研究

Oxygen (Basel, Switzerland) Pub Date : 2023-06-16 DOI: 10.3390/oxygen3020017

D. Chatziharalambous, Chrysoula Kaloteraki, Panagiota Potsaki, Olga Papagianni, Konstantinos Giannoutsos, D. I. Koukoumaki, D. Sarris, K. Gkatzionis, A. Koutelidakis

{"title":"Study of the Total Phenolic Content, Total Antioxidant Activity and In Vitro Digestibility of Novel Wheat Crackers Enriched with Cereal, Legume and Agricultural By-Product Flours","authors":"D. Chatziharalambous, Chrysoula Kaloteraki, Panagiota Potsaki, Olga Papagianni, Konstantinos Giannoutsos, D. I. Koukoumaki, D. Sarris, K. Gkatzionis, A. Koutelidakis","doi":"10.3390/oxygen3020017","DOIUrl":"https://doi.org/10.3390/oxygen3020017","url":null,"abstract":"Wheat-flour crackers represent a staple snack option, although they lack nutritional value. Agricultural by-products such as olive and grape seeds, cereals such as barley and legumes such as lupine and chickpea are rich in bioactive compounds; therefore, flours obtained from those could represent a better option for bakery products fortification. The purpose of the present study was the investigation of total phenolic content and antioxidant activity before and after the baking of wheat crackers enriched with 10–30% olive seed, 10–30% grape seed, 10–40% lupine, 10–30% barley and 20–60% and 80% chickpea flours and the evaluation of the predicted bioavailability after in vitro digestion of crackers demonstrating the highest values. Crackers and doughs were processed and analyzed using Folin–Ciocâlteu and ferric reducing antioxidant power (FRAP) assays, respectively. Crackers with the highest properties were subjected to in vitro gastrointestinal digestion. Baking resulted in an increase in total phenolics and antioxidant activity in the majority of crackers. Olive and grape seed flour crackers demonstrated the highest antioxidant properties. Following in vitro digestion, 30% olive seed flour crackers retained the majority of polyphenols and antioxidant activity. Crackers enriched with 30% olive seed flour could represent a healthy functional bakery snack regarding their increased antioxidant properties.","PeriodicalId":74387,"journal":{"name":"Oxygen (Basel, Switzerland)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48465489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Flow Cytometry of Oxygen and Oxygen-Related Cellular Stress 氧和氧相关细胞应激的流式细胞术

Oxygen (Basel, Switzerland) Pub Date : 2023-06-05 DOI: 10.3390/oxygen3020016

B. Jávega, Guadalupe Herrera, A. Martínez-Romero, J. O'connor

{"title":"Flow Cytometry of Oxygen and Oxygen-Related Cellular Stress","authors":"B. Jávega, Guadalupe Herrera, A. Martínez-Romero, J. O'connor","doi":"10.3390/oxygen3020016","DOIUrl":"https://doi.org/10.3390/oxygen3020016","url":null,"abstract":"Reactive oxygen species (ROS) are unstable and highly reactive molecular forms that play physiological roles in cell signaling and immune defense. However, when ROS generation is not properly balanced by antioxidant defenses, a pathological condition known as oxidative stress arises, in association with the onset and progression of many diseases and conditions, including degeneration and aging. Biomarkers of oxidative stress in biomedicine are actively investigated using different approaches, among which flow cytometry (FCM) and other single-cell, fluorescence-based techniques are most frequent. FCM is an analytical method that measures light scattering and emission of multiple fluorescences by single cells or microscopic particles at a very fast rate. To assess the specific role of ROS in oxidative stress, it is essential to detect and characterize these species accurately. However, the detection and quantitation of individual intracellular ROS and parameters of oxidative stress using fluorogenic substrates and fluorescent probes are still a challenge, because of biological and methodological issues. In this review, we present and discuss a series of complementary strategies to detect ROS or to focus on other endpoints of oxidative stress. Based on our results, we propose some recommendations for proper design of cytometric studies of oxidative stress in order to prevent or minimize the limitations and experimental errors of such approaches.","PeriodicalId":74387,"journal":{"name":"Oxygen (Basel, Switzerland)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48988288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Mechanisms of Mitochondrial Oxidative Stress in Brain Injury: From Pathophysiology to Therapeutics. 脑损伤中线粒体氧化应激的机制：从病理生理学到治疗学。

Oxygen (Basel, Switzerland) Pub Date : 2023-06-01 Epub Date: 2023-04-07 DOI: 10.3390/oxygen3020012

Andrew Nguyen, Anjali B Patel, Ivelina P Kioutchoukova, Michael J Diaz, Brandon Lucke-Wold

引用次数: 0

Comprehensive Assessment of the Antioxidant and Anticancer Potential of Selected Ethnobotanical Plants 少数民族植物抗氧化和抗癌潜力的综合评价

Oxygen (Basel, Switzerland) Pub Date : 2023-05-22 DOI: 10.3390/oxygen3020015

M. Das, Neelu Singh, Paulraj Rajamani

{"title":"Comprehensive Assessment of the Antioxidant and Anticancer Potential of Selected Ethnobotanical Plants","authors":"M. Das, Neelu Singh, Paulraj Rajamani","doi":"10.3390/oxygen3020015","DOIUrl":"https://doi.org/10.3390/oxygen3020015","url":null,"abstract":"Globally, among different types of cancers, breast cancer is identified as the chief cause of mortality among females, and it is a challenge to find new effective treatment strategies with minimal side effects and increased efficacy. Plants are an integral part of the traditional indigenous healthcare system and are becoming the concrete source of new drug discovery. Thus, there is a need to obtain a scientific basis for applying traditionally used plants in cancer treatments that may harbour novel phytochemicals. Therefore, this study aims to investigate the antioxidant and anticancer potential of selected plants of ethnobotanical importance. Five plants of ethnobotanical importance were selected and screened to determine their antioxidant potential through various in vitro free radical scavenging assays (such as DPPH, ABTS, hydroxyl, and superoxide radical scavenging), ferric chelation, and total antioxidant potential, and the total phenolic and flavonoid content was estimated for the selected plants. In contrast, the anticancer potential of crude plant extracts was assessed using MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) against different breast cancer (MCF-7, MDA-MB-231, and MDA-MB-435S) and hepatic cancer cell lines (HepG2), and human PBMCs (peripheral blood mononuclear cells) were used for toxicity studies. The MTT results showed that among all of the crude plant extracts (CAN = Etlingera linguiformis, SES = Sesbania grandiflora, LEX = Smilax ovalifolia, DES = Desmodium triflorum, and CA = Chenopodium album), it was CAN and LEX that showed the best cytotoxic potential on exposed breast cancer cell lines in contrast to SES, DES, and CA. In addition, at the selected dosages that were exposed to breast cancer cells, none of the extracts from any of the five plants showed any cytotoxicity against human PBMCs. Thus, the crude extracts can be explored further for chemopreventive and anticancer activity on murine models to understand their underlying mechanism for effective cancer management.","PeriodicalId":74387,"journal":{"name":"Oxygen (Basel, Switzerland)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43240094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impacts of Varying Blood Flow Restriction Cuff Size and Material on Arterial, Venous and Calf Muscle Pump-Mediated Blood Flow 不同血流限制袖带尺寸和材料对动脉、静脉和小腿肌肉泵介导的血流的影响

Oxygen (Basel, Switzerland) Pub Date : 2023-05-20 DOI: 10.3390/oxygen3020014

Steven B. Machek, Dillon R. Harris, J. Heileson, Dylan T. Wilburn, Jeffrey S. Forsse, D. Willoughby

{"title":"Impacts of Varying Blood Flow Restriction Cuff Size and Material on Arterial, Venous and Calf Muscle Pump-Mediated Blood Flow","authors":"Steven B. Machek, Dillon R. Harris, J. Heileson, Dylan T. Wilburn, Jeffrey S. Forsse, D. Willoughby","doi":"10.3390/oxygen3020014","DOIUrl":"https://doi.org/10.3390/oxygen3020014","url":null,"abstract":"Blood flow restriction (BFR) may become ineffective or potentially dangerous without sufficient standardization. The purpose of this investigation was therefore to (1) assess the viability of multiple sizes of a novel BFR cuff to determine arterial occlusion pressure (AOP) and (2) compare resting arterial, venous and calf muscle pump (cMP)-mediated blood flow between the aforementioned conditions and a commonly employed wide-rigid, tourniquet-style cuff. In randomized, counter-balanced, and crossover fashion, 20 apparently healthy males (18–40 years) donned a widely employed wide-rigid (WR) cuff, along with the largest (NE) and manufacturer-recommended sizes (NER) of a novel narrow-elastic cuff. Participants subsequently assessed AOP, as well as (at 80%AOP) arterial, venous, and venous cMP flow relative to baseline values via ultrasound. All analyses were performed at a significance level of p < 0.05. Analyses revealed a significant condition effect for AOP (p < 0.001; ηp2 = 0.907) whereby WR was significantly lower than both NE and NER; in addition, the latter two did not differ. Compared with baseline, there were no statistically significant differences between cuffs for either arterial or cMP-mediated blood flow. Unsurprisingly, no participants demonstrated venous blood flow at 80% AOP. These findings support the viability of a novel narrow-elastic BFR product, evidenced by consistent AOP acquisition and equivocal blood flow parameters.","PeriodicalId":74387,"journal":{"name":"Oxygen (Basel, Switzerland)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47233085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mitochondria-Stimulating and Antioxidant Effects of Slovak Propolis Varieties on Bovine Spermatozoa 斯洛伐克蜂胶品种对牛精子线粒体的刺激和抗氧化作用

Oxygen (Basel, Switzerland) Pub Date : 2023-04-26 DOI: 10.3390/oxygen3020013

E. Tvrdá, J. Árvay, M. Ďuračka, M. Kačániová

{"title":"Mitochondria-Stimulating and Antioxidant Effects of Slovak Propolis Varieties on Bovine Spermatozoa","authors":"E. Tvrdá, J. Árvay, M. Ďuračka, M. Kačániová","doi":"10.3390/oxygen3020013","DOIUrl":"https://doi.org/10.3390/oxygen3020013","url":null,"abstract":"Propolis is a natural honeybee product, which is known for its beneficial pharmacological effects and use in traditional medicine. This study aspired to investigate the chemical and antioxidant properties of five propolis specimens, followed by the analysis of their in vitro impact on bovine spermatozoa vitality and oxidative profile. Semen samples from 10 breeding bulls were incubated in the absence or presence of 50 µg/mL propolis extracts, and selected sperm quality parameters including motility, mitochondrial activity, cAMP concentration, NAD+/NADH ratio, reactive oxygen species (ROS) and superoxide production were assessed at 2 h and 24 h. Sperm motion behavior and mitochondrial function were stabilized particularly in the presence of propolis collected from Hrabské and Litpovský Hrádok, Slovakia. At the same time, all propolis specimens acted as significant ROS quenchers and stabilized the oxidative milieu of the sperm cultures. Our data suggest that propolis may stabilize the mitochondrial function of spermatozoa while preventing excessive oxidative insults, thereby showing the potential to sustain the sperm motility of extended semen.","PeriodicalId":74387,"journal":{"name":"Oxygen (Basel, Switzerland)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43086141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The On/Off History of Hydrogen in Medicine: Will the Interest Persist This Time Around? 氢在医学上的断断续续的历史：这一次人们的兴趣会持续吗？

Oxygen (Basel, Switzerland) Pub Date : 2023-03-14 DOI: 10.3390/oxygen3010011

Tyler W. LeBaron, K. Ohno, J. Hancock

{"title":"The On/Off History of Hydrogen in Medicine: Will the Interest Persist This Time Around?","authors":"Tyler W. LeBaron, K. Ohno, J. Hancock","doi":"10.3390/oxygen3010011","DOIUrl":"https://doi.org/10.3390/oxygen3010011","url":null,"abstract":"Over 2000 publications including more than 100 human studies seem to indicate that humans have only recently benefited from or known about the medical effects of H2 within the past 15 years. However, we have unknowingly benefited from H2 since the dawn of time, from H2-producing bacteria to the use of naturally occurring hydrogen-rich waters. Moreover, the first writings on the therapeutic effects of H2 date to around 1793. Since then, papers appeared sporadically in the literature every few decades but never exploded until Ohsawa et al. again demonstrated hydrogen’s therapeutic effects in 2007. This landmark paper appears to have been the spark that ignited the medical interest in hydrogen. Although H2 was used in the 1880s to locate intestinal perforations, in the 1940s in deep sea diving, and in the 1960s to measure blood flow, H2 was largely viewed as biologically inert. This review highlights the history of hydrogen in the genesis/evolution of life and its medicinal and non-medicinal use in humans. Although hydrogen medicine has a long and erratic history, perhaps future history will show that, this time around, these 15 years of ignited interest resulted in a self-sustaining explosion of its unique medical effects.","PeriodicalId":74387,"journal":{"name":"Oxygen (Basel, Switzerland)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42238764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Effects of Acute Red Spinach Extract Ingestion on Repeated Sprint Performance in Division I NCAA Female Soccer Athletes 急性摄入红菠菜提取物对NCAA一级女子足球运动员重复冲刺成绩的影响

Oxygen (Basel, Switzerland) Pub Date : 2023-03-09 DOI: 10.3390/oxygen3010010

Mary V. Raymond, Taylor M. Yount, R. Rogers, C. Ballmann

{"title":"Effects of Acute Red Spinach Extract Ingestion on Repeated Sprint Performance in Division I NCAA Female Soccer Athletes","authors":"Mary V. Raymond, Taylor M. Yount, R. Rogers, C. Ballmann","doi":"10.3390/oxygen3010010","DOIUrl":"https://doi.org/10.3390/oxygen3010010","url":null,"abstract":"Red spinach extract is high in inorganic nitrate/nitrite (NO3/NO2) which has been shown to enhance vascular function, cognition, and physical performance. To date, there have been no investigations as to whether red spinach extract serves as an effective strategy to improve repeated exercise performance, which is applicable to many sports and activities. The purpose of this study was to investigate the effect of acute red spinach extract ingestion on repeated sprint ability in female athletes. Eleven Division I NCAA female athletes (ages 18–24) were recruited. In a double-blinded, randomized, counterbalanced design, participants completed two separate visits each with a different treatment: placebo (placebo; tomato juice) or red spinach extract (~400 mg nitrate). For each trial, participants consumed their respective treatment two hours before exercise. Following a warm-up, participants completed 3 × 15 s Wingate Anaerobic Tests (WAnTs) separated by 2 min of recovery. A capillary blood sample was obtained pre-exercise to measure NO2 concentrations. Performance outcomes, heart rate (heart rate), and rate of perceived exertion were measured following each WAnT. Blood lactate (La-) was obtained prior to exercise (PRE) and after the completion of the repeated sprints (POST). Each visit was separated by a minimal recovery period of 72 h. Mean power (p = 0.204), peak power (p = 0.067), heart rate (p = 0.151), and rate of perceived exertion (p = 0.379) were not significantly different between treatments. POST La- concentration was significantly higher with red spinach extract when compared to the placebo (p = 0.030). Furthermore, the fatigue index (p = 0.018) was significantly lower with red spinach extract. The results do not support the use of red spinach extract for the enhancement of power output during repeated anaerobic exercise. However, it may result in improved La-/H+ removal from the muscle, thereby combating physical fatigue.","PeriodicalId":74387,"journal":{"name":"Oxygen (Basel, Switzerland)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49525219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Biochemical and Enzymatic Analyses to Understand the Accumulation of γ-Aminobutyric Acid in Wheat Grown under Flooding Stress 洪水胁迫下小麦γ-氨基丁酸积累的生化和酶学分析

Oxygen (Basel, Switzerland) Pub Date : 2023-03-01 DOI: 10.3390/oxygen3010009

S. Komatsu, Natsuru Nishiyama, Azzahrah Diniyah

{"title":"Biochemical and Enzymatic Analyses to Understand the Accumulation of γ-Aminobutyric Acid in Wheat Grown under Flooding Stress","authors":"S. Komatsu, Natsuru Nishiyama, Azzahrah Diniyah","doi":"10.3390/oxygen3010009","DOIUrl":"https://doi.org/10.3390/oxygen3010009","url":null,"abstract":"Flooding induces low-oxygen stress, which reduces plant growth. The activity of the γ-aminobutyric acid (GABA) shunt is crucial for plant stress adaptation, in which it acts by changing cytosolic pH, limiting reactive oxygen species production, regulating nitrogen metabolism, and bypassing steps in the tricarboxylic acid cycle. GABA accumulates under osmotic stress as well as flooding stress. To clarify the dynamic roles of GABA accumulation in wheat under flooding stress, biochemical and enzymatic analyses were performed using a plant-derived smoke solution (PDSS), which rescued wheat growth from flooding stress. Alcohol dehydrogenase abundance increased under flooding stress; however, under the same conditions, pyruvic acid content increased only following PDSS application. Glutamic acid content increased under flooding stress, but decreased following the application of PDSS after 2 days of flooding. Glutamate decarboxylase abundance and GABA content increased under flooding stress, and further increased after 1 day of application of PDSS. Succinyl semialdehyde dehydrogenase accumulated after 2 days of flooding. These results suggest that flooding stress increases GABA content along with the increase and decrease of glutamate decarboxylase and succinyl semialdehyde dehydrogenase, respectively. Additionally, PDSS increased GABA content along with the increase of glutamate decarboxylase abundance at the initial stage of application.","PeriodicalId":74387,"journal":{"name":"Oxygen (Basel, Switzerland)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46460786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The Underexplored Landscape of Hypoxia-Inducible Factor 2 Alpha and Potential Roles in Tumor Macrophages: A Review. 低氧诱导因子 2 Alpha 的未充分探索景观及在肿瘤巨噬细胞中的潜在作用：综述。

Oxygen (Basel, Switzerland) Pub Date : 2023-03-01 Epub Date: 2023-01-31 DOI: 10.3390/oxygen3010005

Kayla J Steinberger, Timothy D Eubank

{"title":"The Underexplored Landscape of Hypoxia-Inducible Factor 2 Alpha and Potential Roles in Tumor Macrophages: A Review.","authors":"Kayla J Steinberger, Timothy D Eubank","doi":"10.3390/oxygen3010005","DOIUrl":"10.3390/oxygen3010005","url":null,"abstract":"Low tissue oxygenation, termed hypoxia, is a characteristic of solid tumors with negative consequences. Tumor-associated macrophages (TAMs) accumulate in hypoxic tumor regions and correlate with worse outcomes in cancer patients across several tumor types. Thus, the molecular mechanism in which macrophages respond to low oxygen tension has been increasingly investigated in the last decade. Hypoxia stabilizes a group of hypoxia-inducible transcription factors (HIFs) reported to drive transcriptional programs involved in cell survival, metabolism, and angiogenesis. Though both tumor macrophage HIF-1α and HIF-2α correlate with unfavorable tumor microenvironments, most research focuses on HIF-1α as the master regulator of hypoxia signaling, because HIF-1α expression was originally identified in several cancer types and correlates with worse outcome in cancer patients. The relative contribution of each HIFα subunit to cell phenotypes is poorly understood especially in TAMs. Once thought to have overlapping roles, recent investigation of macrophage HIF-2α has demonstrated a diverse function from HIF-1α. Little work has been published on the differential role of hypoxia-dependent macrophage HIF-2α when compared to HIF-1α in the context of tumor biology. This review highlights cellular HIF-2α functions and emphasizes the gap in research investigating oxygen-dependent functions of tumor macrophage HIF-2α.","PeriodicalId":74387,"journal":{"name":"Oxygen (Basel, Switzerland)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10137047/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9399331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0