American Journal of Men's Health最新文献

{"title":"Prognostic Value of Centrosome Replication-Related Genes in Prostate Cancer Based on Transcriptomic and Mendelian Randomization.","authors":"Qizhong Lu, Yufan Wu, Qiwei Yu, Jun Ouyang","doi":"10.1177/15579883251319125","DOIUrl":"10.1177/15579883251319125","url":null,"abstract":"<p><p>Prostate cancer (PCa) is a significant global health concern, with its incidence and mortality rates projected to rise due to population aging. In this study, we utilized PCa transcriptome data from public databases and applied bioinformatics methods to identify three prognostic genes (<i>CDC20</i>, <i>RAD51</i>, and <i>TTK</i>) related to centrosome duplication in PCa. <i>CDC20</i> is involved in cell cycle regulation, <i>RAD51</i> in deoxyribonucleic acid double-strand break repair, and <i>TTK</i> in spindle assembly checkpoint function and cell proliferation. We constructed a risk model and a nomogram model, both demonstrating moderate to good predictive performance with area under the curve values ranging from 0.611 to 0.765 at different time points. Gene set enrichment analysis revealed that these genes were enriched in 64 pathways, including the cell cycle pathway, which is dysregulated in cancer. Furthermore, we analyzed the immune microenvironment and identified 13 differential immune cells and 13 differential immune checkpoints between high- and low-risk groups, providing insights into potential immunotherapy targets for PCa. In conclusion, this study contributes to a deeper understanding of PCa pathogenesis and lays important theoretical and experimental foundations for developing new diagnostic markers and treatment strategies. Future research requires more clinical samples and continued monitoring of the mechanism of these genes in PCa.</p>","PeriodicalId":7429,"journal":{"name":"American Journal of Men's Health","volume":"19 2","pages":"15579883251319125"},"PeriodicalIF":2.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11920994/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143655847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"First-Time Father's Risk Factors of Paternal Perinatal Psychological Distress: A Scoping Review.","authors":"Sadaf Zindani, Julie Chartrand, Jean Hannan, J Craig Phillips","doi":"10.1177/15579883251320035","DOIUrl":"10.1177/15579883251320035","url":null,"abstract":"<p><p>Fathers can experience psychological distress during the paternal perinatal period. The effects of paternal perinatal psychological distress (PPPD) are multileveled. Little research is available about PPPD in first-time fathers. The purpose of this review is to explore the literature on risk factors contributing to PPPD in first-time fathers. The Arksey & O'Malley framework was used to guide this scoping review. The Population, Concept, and Context (PCC) framework was used for answering the review question \"What evidence is available about factors contributing to PPPD in first-time fathers?\" Five databases (CINAHL, EMBASE, MEDLINE, PsycINFO, and PubMed) were used to retrieve relevant, full-text, English references from January 01, 2020, to January 04, 2023. A data extraction tool was developed to identify risk factors assessed in the included studies. The Socio-Ecological Model (SEM) was used for analyzing the extracted data according to the four socio-ecological levels, i.e., individual, relationship, community, and societal. A total of 18 references reporting on 16 studies were included in the review. Fifty-six tools were used for assessing the risk factors contributing to PPPD in first-time fathers. Limited understanding was established about risk factors because tools lacked gender sensitivity. Risk factors aligned with 12 domains (e.g., psychological, relationship, social, and physical). Most domains corresponded with the individual level of SEM. Only two domains corresponded with the societal level of SEM. The literature indicates there are few studies about PPPD experienced by first-time fathers. This scoping review adds to the literature on the mental health care gaps for this population. Further research on measuring PPPD may improve individual and family functioning during the perinatal period.</p>","PeriodicalId":7429,"journal":{"name":"American Journal of Men's Health","volume":"19 2","pages":"15579883251320035"},"PeriodicalIF":2.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11905032/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143613010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Critical Roles of VEGFR1, VEGFR2, VEGFR3, BAX, and BCL-2 in the Pathogenesis of Varicose Veins: Unveiling Molecular Mechanisms.","authors":"Mehdi Abedinzadeh, Alireza Nazari, Seraj-Aldin Vahidi, Soheila Pourmasumi, Hossein Khorramdelazad","doi":"10.1177/15579883251321588","DOIUrl":"10.1177/15579883251321588","url":null,"abstract":"<p><p>Varicocele is characterized by the abnormal dilation of veins within the testicular pampiniform plexus, contributing to inflammation, pain, and infertility in males. The precise roles of vascular endothelial growth factor receptors (VEGFRs), B-cell lymphoma 2 (BCL-2), and BCL-2-associated X-protein (BAX) in the pathology of varicocele still need to be clarified. This study sought to investigate the protein expression levels of VEGFR1, VEGFR2, VEGFR3, BCL-2, and BAX in varicose and healthy vessels from patients diagnosed with varicocele. Tissue samples were collected from 20 varicose veins and 20 healthy vessels from patients diagnosed with varicocele. Western blotting was utilized to quantify VEGFR1, VEGFR2, VEGFR3, BCL-2, and BAX protein levels. Analysis revealed a statistically significant increase in VEGFR3 protein expression within varicose veins compared to healthy vessels (<i>p</i> = .0473), while no significant differences were observed in the levels of VEGFR1 and VEGFR2 between the two groups. Concerning apoptotic signaling proteins, no significant differences were noted in the individual expression levels of BAX and BCL-2; however, the BAX/BCL-2 ratio was approximately 1.29 in varicose vessels. This ratio, exceeding 1.0, may suggest a pro-apoptotic shift in varicose veins and indicates a potential involvement of apoptosis in the pathology of varicocele. These findings suggest that VEGFR3 may play a pivotal role in the pathogenesis of varicocele and could contribute to vascular alterations associated with this condition. Furthermore, the elevated BAX/BCL-2 ratio implies a pro-apoptotic environment within varicose veins, thereby implicating apoptosis as a possible mechanism in the development of varicocele. Further exploration of VEGFR3-related signaling pathways and apoptotic markers may yield valuable insights for identifying therapeutic targets in managing varicocele.</p>","PeriodicalId":7429,"journal":{"name":"American Journal of Men's Health","volume":"19 2","pages":"15579883251321588"},"PeriodicalIF":2.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11907509/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143623197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Domestic Violence Against Men and Its Effect on Marital Satisfaction During the Covid-19 Pandemic in Iran.","authors":"Zahra Kazemi Asl, Fateme Rahmanian, Zahra Rastegari, Seyede Zahra Ghaemi","doi":"10.1177/15579883251322956","DOIUrl":"10.1177/15579883251322956","url":null,"abstract":"<p><p>This study was aimed to investigate the prevalence of domestic violence against men and its effect on marital satisfaction during the Covid-19 pandemic. This cross-sectional study was conducted in the period 2019 to 2020 on 233 men of Estahban city, Iran, who were selected using the convenient sampling method. Data collection instruments were the Demographic Characteristics Checklist, the Domestic Violence Against Men Questionnaire, and the Enrich Marital Satisfaction Questionnaire. Pearson's correlation analysis and multiple linear regression analysis were used for data analysis. The mean scores of the violence and marital satisfaction were 321.08 ± 25.9 and 235 ± 0.13, respectively, and these two variables were significantly correlated (<i>r</i> = .215; <i>p</i> < .001). In addition, the regression analysis showed that the mean score of violence significantly predicted marital satisfaction (<i>p</i> < .05). The study finding showed that the Iranian men faced with a moderate level of domestic violence during the Covid-19 pandemic; therefore, the study concludes that various institutions should design and implement effective strategies to prevent the occurrence of domestic violence and reduce its negative effects on the family.</p>","PeriodicalId":7429,"journal":{"name":"American Journal of Men's Health","volume":"19 2","pages":"15579883251322956"},"PeriodicalIF":2.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11915310/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143655844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Two-Spirit, gay, bisexual, transgender and queer (2SGBTQ) men's suicidality in Canada: A Scoping Review.","authors":"Calvin C Fernandez, Trevor Goodyear, Mark Gilbert, John L Oliffe","doi":"10.1177/15579883251321582","DOIUrl":"10.1177/15579883251321582","url":null,"abstract":"<p><p>Suicide is a leading cause of death in Canada, with men being three times more likely to die from suicide compared with the rest of the population. Among Canadian men, those who are Two-Spirit, gay, bisexual, transgender, and queer (2SGBTQ) are disproportionately impacted by suicidality. Drawing on this growing public health crisis, this current scoping review focuses on Canadian-based 2SGBTQ men to address the research question: <i>What is known about Canadian-based Two-Spirit, gay, bisexual, transgender, and queer (2SGBTQ) men's experiences with suicidality?</i> Keywords related to \"2SGBTQ men\" and \"suicidality\" were searched across five bibliographic databases to derive 25 articles for analysis. Three thematic findings were generated: (a) Methodological Approaches, (b) Social Identities and Stigma, and (c) Psychosocial Health Issues. First, we trace how the study designs, data sources, and sampling methods used in research influence how we know about 2SGBTQ men's suicidality. Second, we report on anti-gay, anti-trans, and HIV stigma as characterizing the diverse associations between 2SGBTQ men's multiple social identities and their suicidality risk. Third, we detail how psychosocial health issues, including mental illness, financial precarity, and substance use, exacerbate social stresses and related risks of suicidality for 2SGBTQ men. These findings map understandings about how suicide risk diversely manifests among subgroups of Canadian-based 2SGBTQ men and interconnections between 2SGBTQ men's social identities, stigma, and their psychosocial health issues. We draw on these learnings to recommend future research priorities regarding 2SGBTQ men's suicidality, alongside opportunities to advance knowledge to inform targeted suicide prevention interventions.</p>","PeriodicalId":7429,"journal":{"name":"American Journal of Men's Health","volume":"19 2","pages":"15579883251321582"},"PeriodicalIF":2.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11877526/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143539761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effects of Xialiqi Capsules in Regulating the Pyroptosis of Prostate Epithelial Cells Via NLRP3/Caspase-1 Pathway for the Treatment of Chronic Prostatitis.","authors":"Zhiming Hong, Zilong Chen, Wenshuo Chen, Junfeng Qiu, Shengjie Wang, Yi Wei, Jun Guo","doi":"10.1177/15579883251322958","DOIUrl":"10.1177/15579883251322958","url":null,"abstract":"<p><p>Chronic prostatitis (CNP) is a prevalent inflammatory disorder among men. The Xialiqi capsule has been reported to alleviate the clinical symptoms of CNP patients, which may be related to its anti-inflammatory effect; yet, its exact mechanism of action remains unclear. In this study, human normal prostate epithelial cells (RWPE-2 cells) were categorized into a control group, a model group, an inhibitor group, along with high, medium, and low drug-containing serum groups (5%, 10%, and 15%, respectively). With the exception of the control group, cell pyroptosis models were created by stimulating with lipopolysaccharide (100 ng/mL) and adenosine triphosphate (5 mM). Subsequently, drug-containing serum and the NOD-like receptor 3 (<i>NLRP3</i>) inhibitor (MCC950) were utilized to intervene with the model cells according to their respective groups. Post-administration of MCC950 and drug-containing serum, an improvement in cell viability was noted in the inhibitor group and medium-high dosage groups (by 20.5%, 38.2%, and 73.2%). Transmission electron microscopy indicated a reduction in the features characteristic of cell pyroptosis. Levels of nitric oxide, interleukin-18 (IL-18), and tumor necrosis factor-α in the cellular supernatant decreased significantly (60.7%, 21.6%, 33.7%, 41.8%; 49.2%, 54.8%, 53.5%, 69.3%; 31.3%, 44.4%, 38.1%, 51.2%). Immunofluorescence showed reduced fluorescence intensity of NLRP3 and Cysteine aspartate protease-1 (Caspase-1) proteins, and Western Blot analysis revealed a significant decline in the expression of NLRP3, pro-Caspase-1, and gasdermin D (20.5%, 45.9%, 58.1%, 74.8%; 23.2%, 36.7%, 51.6%, 51.9%; 15.4%, 28.6%, 33.1%, 39.2%). In vitro experiments suggest that the Xialiqi capsule may treat CNP by regulating prostate epithelial cell pyroptosis and reducing inflammatory factor release via inhibiting the NLRP3/Caspase-1 signaling pathway. This study offers a novel approach for future CNP treatment with traditional Chinese medicine preparations, deserving further promotion.</p>","PeriodicalId":7429,"journal":{"name":"American Journal of Men's Health","volume":"19 2","pages":"15579883251322958"},"PeriodicalIF":2.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11938881/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143690881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Why Men Have Abortions: Quantitative and Qualitative Perspectives From Urban Family Planning Clinics in Chicago, Illinois, USA.","authors":"Jenna M Heath, Brian T Nguyen","doi":"10.1177/15579883241307795","DOIUrl":"10.1177/15579883241307795","url":null,"abstract":"<p><p>Support for abortion is comparable between men and women in the United States; one in five reproductive age men reports abortion involvement. Yet, societal focus on abortion as a uniquely women's issue minimizes men's involvement in abortion. We conducted a secondary analysis of survey (<i>n</i> = 203) and interview data (<i>n</i> = 30) on male partner's experiences accompanying abortion recipients at two family planning clinics in Chicago, Illinois. Respondents identified reasons for abortion from a prepopulated 14-item list. We correlated reasons with respondent's abortion preference and decision satisfaction, characterizing this relationship via thematic analyses of interview transcripts. Nearly all men (97.5%) identified multiple reasons for abortion (median: 6/14), including: mistimed pregnancy (80%), impact on his/his partner's education/career (75%-80%), and finances (71%). Neither individual reasons nor number of reasons was significantly associated with abortion decision preference or decision satisfaction. While 41% would not have chosen abortion, only 10% reported dissatisfaction. Men's perception of decision concordance with their partner was significantly linked to their satisfaction (<i>p</i> < .01). Thematic analysis highlighted complex partner involvement, including shared and deferred decision-making and tension amid demonstrated support. Many abortion-accompanying men preferred to continue the pregnancy, yet very few reported dissatisfaction with the ultimate decision, which may be related to perceived decision concordance with their female partner. Men's decisions for abortion are complex and include varying degrees of male partner involvement and/or decision deferral to female partners.</p>","PeriodicalId":7429,"journal":{"name":"American Journal of Men's Health","volume":"19 1","pages":"15579883241307795"},"PeriodicalIF":2.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11811970/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143389859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Soft Tissue Inflammation of the Arm and Hand Caused by Human Bites.","authors":"Nguyen Dang Duc, Nguyen Phuong Sinh, Lam Nguyen Hong Anh","doi":"10.1177/15579883241309766","DOIUrl":"10.1177/15579883241309766","url":null,"abstract":"<p><p>Wounds caused by human bites have a high infection rate. A 59-year-old male patient came to our poison control center because of soft tissue injuries in the left arm and left hand, pain, swelling, and necrosis. Before entering the hospital, he had a high fever. Physical examination found that the patient's lips were dry, his tongue was dirty, his skin and mucous membranes were less pink, his pulse was 80 beats/min, and his temperature was 36.5°C. Information on May 9, 2024, the patient was bitten on the left arm by a child. The patient had a negative blood culture, a negative burn fluid culture, high-sensitivity C-reactive protein of blood chemistry is 458.1 mg/L, total blood cell analysis with white blood cell is 19.9 G/L, percent of neutrophil is 92.4, soft magnetic resonance imaging of the arm and hand areas with images is cellulitis under the skin of the left arm.The patient was injected with antitetanus toxin serum, antibiotics (Dalacin C, Linezonide, meropenem), and was infused paracetamol. After 1 day of treatment, the patient's condition did not improve and worsened, so the patient was transferred to the National Burn Hospital for further treatment. This article aims to talk about soft tissue injuries due to soft tissue inflammation or necrosis that can occur in patients who are bitten by human. This is the first patient with soft tissue damage with cellulitis under the skin of the left arm known at our poison center.</p>","PeriodicalId":7429,"journal":{"name":"American Journal of Men's Health","volume":"19 1","pages":"15579883241309766"},"PeriodicalIF":2.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11822833/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143405396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mental Health Literacy, Stigma, and Help-Seeking Behavior Among Black Male College Students in Historically Black Universities.","authors":"Bryan Gere, Nahal Salimi","doi":"10.1177/15579883251318214","DOIUrl":"10.1177/15579883251318214","url":null,"abstract":"<p><p>Studies indicate that mental health literacy (MHL) is low among college students. Previous studies report that male college students score lower on MHL than female college students. MHL is connected to mental health help-seeking behavior. Black male college students are shown to be at higher risk for mental health problems such as depression, anxiety, and post-traumatic stress disorder, yet are less likely to seek help for these problems compared with other racial groups. Challenges with mental health can lead to significant negative consequences, such as poor academic performance, social isolation, and even suicide attempts. Stigma has been identified as an important factor that can influence the help-seeking behavior of male college students. Previous research has indicated that Black male college students in predominantly White institutions (PWIs) often struggle with seeking mental health compared with those in Historically Black Universities and Colleges (HBCUs). The purpose of the descriptive cross-sectional study was to investigate the relationships among MHL, stigma, and help-seeking behavior among Black males at HBCUs. The results indicate that having better mental health knowledge is linked to seeking help more often, stressing the need to enhance mental health understanding for better support-seeking. Seeking help was positively associated with reduced stigma. The implications for practitioners, policymakers, and administrators were explored, emphasizing the need for targeted, culturally sensitive interventions for young Black men in higher education. This study underscores the importance of addressing their specific challenges to enhance mental health and academic outcomes.</p>","PeriodicalId":7429,"journal":{"name":"American Journal of Men's Health","volume":"19 1","pages":"15579883251318214"},"PeriodicalIF":2.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11848867/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143482066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Abnormal Ultrasound Characteristics of Seminal Vesicles in Patient With Anejaculation: A Case Report.","authors":"Dawei Gao, Qi Gao, Han Yin, Baofang Jin, Dalin Sun","doi":"10.1177/15579883251316257","DOIUrl":"10.1177/15579883251316257","url":null,"abstract":"<p><p>Anejaculation (AE) has long been a challenging issue in andrology due to its low clinical reporting rate, leading to an insufficient understanding within the academic community. This case report discusses a 52-year-old AE patient with a long-term history of diabetes mellitus. His seminal vesicles ultrasound images revealed a notable absence of anechoic polycyclic areas, a characteristic not previously reported in AE patients. We hypothesize that this finding is attributable to diabetes-induced seminal vesicles secretory dysfunction, leading to AE in this patient. This case underscores the importance of anechoic polycyclic areas in the physiology of ejaculation and highlights the necessity for further research into the correlation between these areas and various types of ejaculatory disorders, aiming to provide valuable insights for the medical community.</p>","PeriodicalId":7429,"journal":{"name":"American Journal of Men's Health","volume":"19 1","pages":"15579883251316257"},"PeriodicalIF":2.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11863220/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143481965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}