Nature synthesis最新文献_第9页

Interfacially coupled Cu-cluster/GaN photocathode for efficient CO2 to ethylene conversion 用于将二氧化碳高效转化为乙烯的簇间耦合铜/氮化镓光电阴极

Nature synthesis Pub Date : 2024-09-12 DOI: 10.1038/s44160-024-00648-9

Bingxing Zhang, Peng Zhou, Zhengwei Ye, Ishtiaque Ahmed Navid, Yuyang Pan, Yixin Xiao, Kai Sun, Zetian Mi

{"title":"Interfacially coupled Cu-cluster/GaN photocathode for efficient CO2 to ethylene conversion","authors":"Bingxing Zhang, Peng Zhou, Zhengwei Ye, Ishtiaque Ahmed Navid, Yuyang Pan, Yixin Xiao, Kai Sun, Zetian Mi","doi":"10.1038/s44160-024-00648-9","DOIUrl":"10.1038/s44160-024-00648-9","url":null,"abstract":"The photoelectrochemical synthesis of valuable multicarbon products from carbon dioxide, sunlight and water is a promising pathway for clean energy generation and carbon neutrality. However, it is challenging to create and stabilize efficient C–C coupling sites to achieve multicarbon products with high selectivity, yield and stability. Here we designed a low-coordinated copper-cluster catalyst interfacially coupled in situ with a GaN nanowire photocathode, achieving a high ethylene Faradaic efficiency of ∼61% and a partial current density of 14.2 mA cm−2, with a robust stability of ∼116 h. The in situ self-optimized Ga–N–O interface was confirmed to facilitate and stabilize the interfacially oxidized copper species of copper clusters, which function as efficient C–C coupling sites for ethylene production. Furthermore, the hydrogen-feeding effect of GaN for promoting CO hydrogenation also guides the facile CHO-involved C–C coupling pathway. This work sheds light on the interface design and understanding of efficient and stable (photo)electrosynthesis of highly valuable fuels from CO2. An interfacially coupled Cu-cluster/GaN photocathode is designed to overcome the efficiency and stability bottlenecks in photoelectrochemical CO2 reduction to multicarbon products. The self-optimized Ga–N–O interface facilitates and stabilizes interfacially oxidized copper species of copper clusters, which function as efficient C–C coupling sites for ethylene production.","PeriodicalId":74251,"journal":{"name":"Nature synthesis","volume":"3 12","pages":"1567-1576"},"PeriodicalIF":0.0,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142195611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Computational analysis of modular diazotransfer reactions for the development of predictive reactivity models and diazotransfer reagents 对模块重氮转移反应进行计算分析，以开发预测性反应模型和重氮转移试剂

Nature synthesis Pub Date : 2024-09-10 DOI: 10.1038/s44160-024-00633-2

Meng-Meng Zheng, Liu Cai, Tiancheng Ma, Hao-Dong Tan, Xiaoyu Lai, Jiajia Dong, Xiao-Song Xue

{"title":"Computational analysis of modular diazotransfer reactions for the development of predictive reactivity models and diazotransfer reagents","authors":"Meng-Meng Zheng, Liu Cai, Tiancheng Ma, Hao-Dong Tan, Xiaoyu Lai, Jiajia Dong, Xiao-Song Xue","doi":"10.1038/s44160-024-00633-2","DOIUrl":"10.1038/s44160-024-00633-2","url":null,"abstract":"The development of the sulfur(VI)–fluoride exchange (SuFEx) and modular diazotransfer (MoDAT) reactions represent important milestones in the evolution of click chemistry. However, their reactivity profiles, chemoselectivity origins and underlying mechanisms remain unclear. Here we report a computational study of the MoDAT and SuFEx pathways, focusing on the reaction between the diazotransfer reagent fluorosulfuryl azide and primary amines. Our calculations reveal that the MoDAT reaction possesses a small kinetic barrier and a strong driving force, making it kinetically and thermodynamically more favourable than the SuFEx reaction. Through mechanistic scrutiny and structure–activity relationship studies, we have formulated predictive models for the reactivity and selectivity of the MoDAT reaction. Leveraging these insights, an easy-to-prepare and easily handled diazotransfer reagent with excellent reactivity has been developed, which holds broad promise for applications in chemistry and biology. Computational analysis of competing sulfur(VI)–fluoride exchange and modular diazotransfer pathways in the reaction between primary amines and fluorosulfuryl azide reveals that diazotransfer is more kinetically and thermodynamically favoured. Predictive models are formulated by combining mechanistic analysis and structure–activity relationship studies, enabling the development of an easy-to-prepare and highly reactive diazotransfer reagent.","PeriodicalId":74251,"journal":{"name":"Nature synthesis","volume":"3 12","pages":"1507-1517"},"PeriodicalIF":0.0,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142195626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Computationally guided design of a diazotransfer reagent with high reactivity 高反应性重氮转移试剂的计算引导设计

Nature synthesis Pub Date : 2024-09-10 DOI: 10.1038/s44160-024-00634-1

引用次数: 0

Selective cross-hydrodimerization of alkenes 烯烃的选择性交叉二聚化

Nature synthesis Pub Date : 2024-09-09 DOI: 10.1038/s44160-024-00635-0

Sudip Maiti, Debabrata Maiti

引用次数: 0

Forging out-of-equilibrium supramolecular gels 锻造失衡超分子凝胶

Nature synthesis Pub Date : 2024-09-06 DOI: 10.1038/s44160-024-00623-4

Simona Bianco, Fin Hallam Stewart, Santanu Panja, Asra Zyar, Emma Bowley, Marko Bek, Roland Kádár, Ann Terry, Roberto Appio, Tomás S. Plivelic, Mahon Maguire, Harish Poptani, Marco Marcello, Ravi R. Sonani, Edward H. Egelman, Dave J. Adams

{"title":"Forging out-of-equilibrium supramolecular gels","authors":"Simona Bianco, Fin Hallam Stewart, Santanu Panja, Asra Zyar, Emma Bowley, Marko Bek, Roland Kádár, Ann Terry, Roberto Appio, Tomás S. Plivelic, Mahon Maguire, Harish Poptani, Marco Marcello, Ravi R. Sonani, Edward H. Egelman, Dave J. Adams","doi":"10.1038/s44160-024-00623-4","DOIUrl":"10.1038/s44160-024-00623-4","url":null,"abstract":"The design of supramolecular hydrogels comprising aligned domains is important for the fabrication of biomimetic materials and applications in optoelectronics. One way to access such materials is by the self-assembly of small molecules into long fibres, which can be aligned using an external stimulus. Out-of-equilibrium supramolecular gels can also be designed, where pre-programmed changes of state can be induced by the addition of chemical fuels. Here we exploit these dynamic properties to form materials with aligned domains through a ‘forging’ approach: an external force is used to rearrange the underlying network from random to aligned fibres as the system undergoes a pre-programmed gel-to-sol-to-gel transition. We show that we can predictably organize the supramolecular fibres, leading to controllable formation of materials with aligned domains through a high degree of temporal control. Dynamic supramolecular systems can be designed to adapt phases in a pre-programmable way. Here the transient nature of a gel system is exploited, in combination with the application of mechanical stimuli, to obtain soft materials with aligned fibres in a controllable way.","PeriodicalId":74251,"journal":{"name":"Nature synthesis","volume":"3 12","pages":"1481-1489"},"PeriodicalIF":0.0,"publicationDate":"2024-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s44160-024-00623-4.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142195614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis pathways to thin films of stable layered nitrides 稳定层状氮化物薄膜的合成途径

Nature synthesis Pub Date : 2024-09-06 DOI: 10.1038/s44160-024-00643-0

Andriy Zakutayev, Matthew Jankousky, Laszlo Wolf, Yi Feng, Christopher L. Rom, Sage R. Bauers, Olaf Borkiewicz, David A. LaVan, Rebecca W. Smaha, Vladan Stevanovic

{"title":"Synthesis pathways to thin films of stable layered nitrides","authors":"Andriy Zakutayev, Matthew Jankousky, Laszlo Wolf, Yi Feng, Christopher L. Rom, Sage R. Bauers, Olaf Borkiewicz, David A. LaVan, Rebecca W. Smaha, Vladan Stevanovic","doi":"10.1038/s44160-024-00643-0","DOIUrl":"10.1038/s44160-024-00643-0","url":null,"abstract":"Controlled synthesis of metastable materials away from equilibrium is of interest in materials chemistry. Thin-film deposition methods with rapid condensation of vapour precursors can readily synthesize metastable phases but often struggle to yield the thermodynamic ground state. Growing thermodynamically stable structures using kinetically limited synthesis methods is important for practical applications in electronics and energy conversion. Here we reveal a synthesis pathway to thermodynamically stable, ordered layered ternary nitride materials, and discuss why disordered metastable intermediate phases tend to form. We show that starting from elemental vapour precursors leads to a 3D long-range-disordered MgMoN2 thin-film metastable intermediate structure, with a layered short-range order that has a low-energy transformation barrier to the layered 2D-like stable structure. This synthesis approach is extended to ScTaN2, MgWN2 and MgTa2N3, and may lead to the synthesis of other layered nitride thin films with unique semiconducting and quantum properties. Synthesis of metastable materials away from thermodynamic equilibrium has been a challenge in materials chemistry, but thin-film methods often struggle to yield ground-state structures. Now, a synthesis pathway to thin films of stable layered ternary nitrides is revealed, and the tendency for metastable intermediate formation is discussed.","PeriodicalId":74251,"journal":{"name":"Nature synthesis","volume":"3 12","pages":"1471-1480"},"PeriodicalIF":0.0,"publicationDate":"2024-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142195616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Stereospecific C–O sulfation via persulfate-induced 1,4-metallate migration 通过过硫酸盐诱导的 1,4-金属铝迁移进行立体特异性 C-O 硫化反应

Nature synthesis Pub Date : 2024-09-05 DOI: 10.1038/s44160-024-00636-z

Zetao Zhao, Qian Yu, Zhen Xia, Zhongyao Ye, Xuejin Huang, Chunlan Song, Jiakun Li

{"title":"Stereospecific C–O sulfation via persulfate-induced 1,4-metallate migration","authors":"Zetao Zhao, Qian Yu, Zhen Xia, Zhongyao Ye, Xuejin Huang, Chunlan Song, Jiakun Li","doi":"10.1038/s44160-024-00636-z","DOIUrl":"10.1038/s44160-024-00636-z","url":null,"abstract":"Sulfation, a ubiquitous post-translational modification in biomolecules, primarily targets substrates containing OH groups through O-sulfonation (O–SO3). A method for sulfation via the formation of C–O bonds has the potential to access organic sulfates from a broad substrate scope and in a stereoselective manner but remains elusive. Stereospecific C–O bond formation via 1,2-metallate migration in peroxide oxidation has not been deployed to create any other valuable C–O bonds apart from C–OH. Here we describe a fundamentally unique reactivity of persulfate salts for stereospecific C–O sulfation via 1,4-metallate migration. With the aid of readily accessible, stereodefined organic boron compounds derived from native functionalities and a tandem borylation–sulfation approach, our study thus expands to include hydrosulfation of alkenes, C–H sulfation, decarboxylative sulfation, dehalogenative sulfation and deaminative sulfation, which are not otherwise readily accessible. O-sulfonation is a common method for producing organosulfates but is limited to hydroxyl compounds. Here the unique reactivity of persulfates enables stereospecific C–O sulfation via 1,4-metallate migration. This approach provides an unprecedented platform to readily access structurally diverse organosulfates from a wide substrate scope.","PeriodicalId":74251,"journal":{"name":"Nature synthesis","volume":"3 12","pages":"1529-1537"},"PeriodicalIF":0.0,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142195622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mechanically rigid metallopeptide nanostructures achieved by highly efficient folding 通过高效折叠实现机械刚性金属肽纳米结构

Nature synthesis Pub Date : 2024-09-05 DOI: 10.1038/s44160-024-00640-3

Xing Kang, Li Wang, Bingyu Liu, Shuyi Zhou, Yingguo Li, Shuai-Liang Yang, Rui Yao, Liang Qiao, Xiao Wang, Wei Gong, Yan Liu, Leilei Shi, Jinqiao Dong, Yong Cui, Anthony P. Davis

{"title":"Mechanically rigid metallopeptide nanostructures achieved by highly efficient folding","authors":"Xing Kang, Li Wang, Bingyu Liu, Shuyi Zhou, Yingguo Li, Shuai-Liang Yang, Rui Yao, Liang Qiao, Xiao Wang, Wei Gong, Yan Liu, Leilei Shi, Jinqiao Dong, Yong Cui, Anthony P. Davis","doi":"10.1038/s44160-024-00640-3","DOIUrl":"10.1038/s44160-024-00640-3","url":null,"abstract":"Natural proteins must fold into complex three-dimensional structures to achieve excellent mechanical properties vital for biological functions, but this has proven to be exceptionally difficult to control in synthetic systems. As such, the long-standing issue of low mechanical rigidity and stability induced by misfolding constrains the physical and chemical properties of self-assembling peptide materials. Here we introduce a mixed-chirality strategy that enhances folding efficiency in topologically interlocked metallopeptide nanostructures. The orderly entanglement of heterochiral peptide-derived linkers can fold into a compact three-dimensional catenane. These folding-mediated secondary structural changes not only generate biomimetic binding pockets derived from individual peptide strands but also result in strong chiral amplification by the tight interlocking manner. Notably, this strategic ‘chirality mutation’ alters their arrangement into tertiary structures and is pivotal in achieving exceptional mechanical rigidity observed in the metallopeptide crystals, which exhibit a Young’s modulus of 157.6 GPa, approximately tenfold higher than the most rigid proteinaceous materials in nature. This unusual nature is reflected in enhanced peptide-binding properties and heightened antimicrobial activities relative to its unfolded counterpart. A strategy is introduced for promoting the folding in metallopeptide nanostructures, resulting in high mechanical rigidity. The mechanical properties are reflected in enhanced peptide-binding properties and heightened antimicrobial activities relative to their unfolded counterparts.","PeriodicalId":74251,"journal":{"name":"Nature synthesis","volume":"4 1","pages":"43-52"},"PeriodicalIF":0.0,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s44160-024-00640-3.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142195624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Light-enabled scalable synthesis of bicyclo[1.1.1]pentane halides and their functionalizations 双环[1.1.1]戊烷卤化物及其功能化的光致可扩展合成

Nature synthesis Pub Date : 2024-09-05 DOI: 10.1038/s44160-024-00637-y

Vasyl Ripenko, Vadym Sham, Vitalina Levchenko, Serhii Holovchuk, Daniil Vysochyn, Ivan Klymov, Dmytro Kyslyi, Stanislav Veselovych, Serhii Zhersh, Yurii Dmytriv, Andrey Tolmachev, Iryna Sadkova, Irina Pishel, Kateryna Horbatok, Viktoria Kosach, Yelyzaveta Nikandrova, Pavel K. Mykhailiuk

{"title":"Light-enabled scalable synthesis of bicyclo[1.1.1]pentane halides and their functionalizations","authors":"Vasyl Ripenko, Vadym Sham, Vitalina Levchenko, Serhii Holovchuk, Daniil Vysochyn, Ivan Klymov, Dmytro Kyslyi, Stanislav Veselovych, Serhii Zhersh, Yurii Dmytriv, Andrey Tolmachev, Iryna Sadkova, Irina Pishel, Kateryna Horbatok, Viktoria Kosach, Yelyzaveta Nikandrova, Pavel K. Mykhailiuk","doi":"10.1038/s44160-024-00637-y","DOIUrl":"10.1038/s44160-024-00637-y","url":null,"abstract":"In 2012, bicyclo[1.1.1]pentanes were demonstrated to be bioisosteres of the benzene ring. Here, we report a general scalable reaction between alkyl iodides and propellane that provides bicyclo[1.1.1]pentane iodides in milligram, gram and even kilogram quantities. The reaction is performed in flow and requires just light; no catalysts, initiators or additives are needed. The reaction is clean enough that, in many cases, evaporation of the reaction mixture provides products in around 90% purity that can be directly used in further transformations without any purification. Combined with the subsequent functionalization, >300 bicyclo[1.1.1]pentanes for medicinal chemistry have been prepared. So far, this is the most general and scalable approach towards functionalized bicyclo[1.1.1]pentanes. A general and scalable approach to prepare functionalized bicyclo[1.1.1]pentanes is reported. The key reaction between alkyl iodides and propellane is performed in flow and requires just light; no catalysts, initiators or additives are needed. Combined with the subsequent functionalization, >300 bicyclo[1.1.1]pentanes for medicinal chemistry have been prepared.","PeriodicalId":74251,"journal":{"name":"Nature synthesis","volume":"3 12","pages":"1538-1549"},"PeriodicalIF":0.0,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s44160-024-00637-y.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142195631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A hetero-supermolecular-building-block strategy for the assembly of porous (3,12,24)-connected uru metal–organic frameworks 组装多孔 (3,12,24) 连接乌鲁金属有机框架的异种超分子构建块策略

Nature synthesis Pub Date : 2024-09-05 DOI: 10.1038/s44160-024-00622-5

Le Shi, Yuanlong Zhong, Honghao Cao, Hao Wang, Zhangyi Xiong, Kun Wang, Hanyang Shen, Zhijie Chen

{"title":"A hetero-supermolecular-building-block strategy for the assembly of porous (3,12,24)-connected uru metal–organic frameworks","authors":"Le Shi, Yuanlong Zhong, Honghao Cao, Hao Wang, Zhangyi Xiong, Kun Wang, Hanyang Shen, Zhijie Chen","doi":"10.1038/s44160-024-00622-5","DOIUrl":"10.1038/s44160-024-00622-5","url":null,"abstract":"Supermolecular building block (SBB) approaches have been widely used for synthesizing highly connected metal–organic frameworks (MOFs). However, it remains a challenge to synthesize trinodal MOFs via SBB approaches. Here we report the assembly of (3,12,24)-connected uru-MOFs via a hetero-supermolecular-building-block (hetero-SBB) strategy, that is, using different types of highly connected metal–organic polyhedra (MOPs) as building units. This hetero-SBB strategy allows the facile synthesis of previously inaccessible uru-MOFs via 12-connected cuboctahedral and 24-connected rhombicuboctahedral MOPs. The uru-MOF-1, consisting of hierarchical microporous and mesoporous cages, exhibits a Brunauer–Emmett–Teller area of 3,170 m2 g−1. This MOF shows a high methane uptake of 339.6 cm3 (standard temperature and pressure) cm−3 at 159 K and 10 bar and is a promising candidate for low-temperature methane storage. The hetero-SBB strategy paves a way for the designed synthesis of highly connected MOFs, which are difficult to synthesize via traditional strategies, by taking advantage of the arsenal of synthetic MOPs. The synthesis of isoreticular (3,12,24)-connected uru metal–organic frameworks (MOFs) is reported by the assembly of 12-connected cuboctahedral and 24-connected rhombicuboctahedral supermolecular building blocks. The resulting uru-MOF-1 is a promising candidate for low-temperature methane storage.","PeriodicalId":74251,"journal":{"name":"Nature synthesis","volume":"3 12","pages":"1560-1566"},"PeriodicalIF":0.0,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142195623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0