Nature synthesis最新文献

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Autonomous laboratories and digital chemistry in industry 工业中的自主实验室和数字化学
IF 22.6
Nature synthesis Pub Date : 2026-07-20 DOI: 10.1038/s44160-026-01114-4
Peter Seavill
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引用次数: 0
Enantioselective single-atom skeletal editing of bicyclo[1.1.0]butanes by carbene insertion 碳插入法对双环[1.1.0]丁烷的单原子骨架编辑
Nature synthesis Pub Date : 2026-07-17 DOI: 10.1038/s44160-026-01118-0
Yongquan Ning, Shaopeng Liu, Yixuan Wang, Chenxu Wang, Paramasivam Sivaguru, Wei Song, Jun Yang, Weitao Zhang, Xihe Bi
{"title":"Enantioselective single-atom skeletal editing of bicyclo[1.1.0]butanes by carbene insertion","authors":"Yongquan Ning, Shaopeng Liu, Yixuan Wang, Chenxu Wang, Paramasivam Sivaguru, Wei Song, Jun Yang, Weitao Zhang, Xihe Bi","doi":"10.1038/s44160-026-01118-0","DOIUrl":"https://doi.org/10.1038/s44160-026-01118-0","url":null,"abstract":"","PeriodicalId":74251,"journal":{"name":"Nature synthesis","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148459360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synthesis of a 524-atom bifurcated molecular knot 524个原子分叉分子结的合成
Nature synthesis Pub Date : 2026-07-16 DOI: 10.1038/s44160-026-01117-1
{"title":"Synthesis of a 524-atom bifurcated molecular knot","authors":"","doi":"10.1038/s44160-026-01117-1","DOIUrl":"https://doi.org/10.1038/s44160-026-01117-1","url":null,"abstract":"","PeriodicalId":74251,"journal":{"name":"Nature synthesis","volume":"73 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148459856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assembly of a bifurcated knot via sequence selective imine condensation 通过序列选择性亚胺缩合组装分叉结
Nature synthesis Pub Date : 2026-07-16 DOI: 10.1038/s44160-026-01115-3
James T. F. Dobson, Jack A. Davies, Tanya K. Ronson, Andrew Tarzia, Xiang Sun, Kim E. Jelfs, Jonathan R. Nitschke
{"title":"Assembly of a bifurcated knot via sequence selective imine condensation","authors":"James T. F. Dobson, Jack A. Davies, Tanya K. Ronson, Andrew Tarzia, Xiang Sun, Kim E. Jelfs, Jonathan R. Nitschke","doi":"10.1038/s44160-026-01115-3","DOIUrl":"https://doi.org/10.1038/s44160-026-01115-3","url":null,"abstract":"Knotting and weaving, at both macroscopic and molecular scales, play an essential role in determining the physical properties of materials. While classical crossing points in molecular knots have been extensively studied, synthetic bifurcated knots, containing characteristic junctions where a strand divides into two branches, represent an underexplored class of topologically complex molecular knots. Although reports of such structures are rare due to synthetic challenges, natural bifurcated knots have been identified in proteins and linked to potentially enhancing protein robustness. Here we report the synthesis of a 524-atom bifurcated knot featuring 3 classical crossings and 20 bifurcated junctions via 2 sequential, selective, imine condensations. First, Zn <jats:sup>II</jats:sup> ions are used to template the subcomponent self-assembly of a Zn <jats:sup>II</jats:sup> <jats:sub>8</jats:sub> L <jats:sub>6</jats:sub> architecture, with three unreacted aldehyde groups protruding from each of its eight vertices. Second, a geometry-matching tris-aniline condenses with these terminal aldehydes, yielding a covalently linked bifurcated knot with enhanced robustness, as quantified using collision-induced dissociation mass spectrometry. We anticipate that this approach will facilitate the design of new mechanically interlocked molecules and highly entangled molecular materials with increased robustness.","PeriodicalId":74251,"journal":{"name":"Nature synthesis","volume":"54 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148459362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rotaxane synthesis inside out 由内而外合成轮烷
IF 22.6
Nature synthesis Pub Date : 2026-07-15 DOI: 10.1038/s44160-026-01129-x
Jet-Sing M. Lee
{"title":"Rotaxane synthesis inside out","authors":"Jet-Sing M. Lee","doi":"10.1038/s44160-026-01129-x","DOIUrl":"10.1038/s44160-026-01129-x","url":null,"abstract":"","PeriodicalId":74251,"journal":{"name":"Nature synthesis","volume":"5 8","pages":"1135-1135"},"PeriodicalIF":22.6,"publicationDate":"2026-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148459858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enantioconvergent alkylation of boron-stabilized organomagnesiums with unactivated alkyl halides using nickel catalysis 镍催化下硼稳定有机镁与未活化卤化烷基的对映收敛烷基化反应
Nature synthesis Pub Date : 2026-07-14 DOI: 10.1038/s44160-026-01107-3
Semin Lee, Seungcheol Han, Joeun Choi, Seung Hwan Cho
{"title":"Enantioconvergent alkylation of boron-stabilized organomagnesiums with unactivated alkyl halides using nickel catalysis","authors":"Semin Lee, Seungcheol Han, Joeun Choi, Seung Hwan Cho","doi":"10.1038/s44160-026-01107-3","DOIUrl":"https://doi.org/10.1038/s44160-026-01107-3","url":null,"abstract":"","PeriodicalId":74251,"journal":{"name":"Nature synthesis","volume":"221 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148432507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hydrogenation of viologens mediated by formic acid 甲酸介导致病菌的氢化反应
IF 22.6
Nature synthesis Pub Date : 2026-07-14 DOI: 10.1038/s44160-026-01109-1
{"title":"Hydrogenation of viologens mediated by formic acid","authors":"","doi":"10.1038/s44160-026-01109-1","DOIUrl":"10.1038/s44160-026-01109-1","url":null,"abstract":"A mild, metal-free hydrogenation strategy converts rigid viologens into flexible piperidine and piperidine derivatives using formic acid as a sustainable reductant. This transformation enables structural characterization by single-crystal X-ray diffraction and gives products with enhanced antibacterial activity compared with their viologen counterparts, expanding the functional scope of viologen-based materials.","PeriodicalId":74251,"journal":{"name":"Nature synthesis","volume":"5 10","pages":"1490-1491"},"PeriodicalIF":22.6,"publicationDate":"2026-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148432512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
β-Selective C(sp3)–H functionalization of alkyl boronates using photoredox catalysis 利用光氧化还原催化β-选择性C(sp3) -H功能化硼酸烷基酯
Nature synthesis Pub Date : 2026-07-10 DOI: 10.1038/s44160-026-01106-4
Partha Sarathi Hazra, Makaya Robinson, M. Kevin Brown
{"title":"β-Selective C(sp3)–H functionalization of alkyl boronates using photoredox catalysis","authors":"Partha Sarathi Hazra, Makaya Robinson, M. Kevin Brown","doi":"10.1038/s44160-026-01106-4","DOIUrl":"https://doi.org/10.1038/s44160-026-01106-4","url":null,"abstract":"","PeriodicalId":74251,"journal":{"name":"Nature synthesis","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148432508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synthesis of Z‑allylamines via masked alkenyl anions from alkynyl tetracoordinate boron compounds 炔基四配位硼化合物用掩膜烯基阴离子合成Z -烯丙胺
Nature synthesis Pub Date : 2026-07-09 DOI: 10.1038/s44160-026-01116-2
Yuanbiao An, Yifei Zhu, Xingxing Ma, Peiyu Zhang, Qiuling Song
{"title":"Synthesis of Z‑allylamines via masked alkenyl anions from alkynyl tetracoordinate boron compounds","authors":"Yuanbiao An, Yifei Zhu, Xingxing Ma, Peiyu Zhang, Qiuling Song","doi":"10.1038/s44160-026-01116-2","DOIUrl":"https://doi.org/10.1038/s44160-026-01116-2","url":null,"abstract":"","PeriodicalId":74251,"journal":{"name":"Nature synthesis","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148432191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multi-walled carbon nanotube network-toughened diamond composite via atomic interface continuity 基于原子界面连续性的多壁碳纳米管网络增韧金刚石复合材料
Nature synthesis Pub Date : 2026-07-09 DOI: 10.1038/s44160-026-01113-5
Jiawei Zhang, Keliang Qiu, Tengfei Xu, Xi Shen, Junkai Li, Fengjiao Li, Richeng Yu, Huiyang Gou, Duanwei He, Liping Wang, Zhongzhou Wang, Guodong Li, Yusheng Zhao, Ke Chen, Fang Hong, Ruifeng Zhang, Xiaohui Yu
{"title":"Multi-walled carbon nanotube network-toughened diamond composite via atomic interface continuity","authors":"Jiawei Zhang, Keliang Qiu, Tengfei Xu, Xi Shen, Junkai Li, Fengjiao Li, Richeng Yu, Huiyang Gou, Duanwei He, Liping Wang, Zhongzhou Wang, Guodong Li, Yusheng Zhao, Ke Chen, Fang Hong, Ruifeng Zhang, Xiaohui Yu","doi":"10.1038/s44160-026-01113-5","DOIUrl":"https://doi.org/10.1038/s44160-026-01113-5","url":null,"abstract":"","PeriodicalId":74251,"journal":{"name":"Nature synthesis","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148432192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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