Nature synthesis最新文献_第6页

Anomalous in-plane electrical anisotropy in elemental metal nanosheets 单质金属纳米片的面内异常电各向异性

Nature synthesis Pub Date : 2024-10-31 DOI: 10.1038/s44160-024-00669-4

Taehoon Kim, Dongchul Seo, Sungsoon Kim, Gyu Won Kim, Seung-Jae Shin, Se Young Kim, Minwoo Lee, Jihong Bae, Hansol Ra, Minjun Kim, Taeyoung Kim, Soyeon Lee, Seung-Rok Kim, Hyunmin Cho, Han Joo Lee, Jaehyeok Choi, Seongil Im, Jin-Woo Park, Jinwoo Cheon, Joon Sang Lee, Aron Walsh, Wooyoung Shim

{"title":"Anomalous in-plane electrical anisotropy in elemental metal nanosheets","authors":"Taehoon Kim, Dongchul Seo, Sungsoon Kim, Gyu Won Kim, Seung-Jae Shin, Se Young Kim, Minwoo Lee, Jihong Bae, Hansol Ra, Minjun Kim, Taeyoung Kim, Soyeon Lee, Seung-Rok Kim, Hyunmin Cho, Han Joo Lee, Jaehyeok Choi, Seongil Im, Jin-Woo Park, Jinwoo Cheon, Joon Sang Lee, Aron Walsh, Wooyoung Shim","doi":"10.1038/s44160-024-00669-4","DOIUrl":"10.1038/s44160-024-00669-4","url":null,"abstract":"Two-dimensional (2D) elemental metals, often overlooked owing to their lack of switching or dielectric properties, have the potential to exhibit unique properties unachievable by their bulk counterparts if their microstructure can be controlled. Here we propose an electrodeposition method that utilizes a confined 2D template to prepare elemental metal nanosheets with an aligned grain orientation, resulting in an exceptionally high in-plane electrical anisotropy of >103. Heterogeneous nucleation is initiated and the directed growth of the metal at the cathode is controlled within a channel whose size is smaller than the critical size of the nuclei. This leads to the formation of anisotropic microstructures, and consequently, the nanosheets exhibit anisotropic electrical properties. Unlike conventional field-effect transistors, devices employing a channel with two orthogonally separated conduction paths yield an exceptional on–off switching ratio exceeding 104. Our approach offers a promising route to produce various 2D elemental metals with properties different from those observed in their bulk counterparts and highlights the potential of anisotropic metallic nanosheets as switching elements. An electrodeposition method is proposed for the growth of elemental metal nanosheets with aligned grain orientation using a confined 2D template. Nucleation and growth are controlled within a confined 2D channel, resulting in nanosheets with high in-plane electrical anisotropy (>103), highlighting their potential as switching elements.","PeriodicalId":74251,"journal":{"name":"Nature synthesis","volume":"4 1","pages":"31-42"},"PeriodicalIF":0.0,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142995874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Extended-release capsule-inspired electrocatalyst design 缓释胶囊式电催化剂设计

Nature synthesis Pub Date : 2024-10-31 DOI: 10.1038/s44160-024-00674-7

Yuanjun Chen, Edward H. Sargent

引用次数: 0

From furans to pyrroles 从呋喃到吡咯

Nature synthesis Pub Date : 2024-10-28 DOI: 10.1038/s44160-024-00682-7

Thomas West

引用次数: 0

Electrochemical etherification and amination 电化学醚化和胺化

Nature synthesis Pub Date : 2024-10-25 DOI: 10.1038/s44160-024-00684-5

Peter W. Seavill

引用次数: 0

Multisite modifications of arenes using ketones as removable handles enabled by Pd and norbornene cooperative catalysis Pd和降冰片烯协同催化下，以酮为可移动把手的芳烃多位点修饰

Nature synthesis Pub Date : 2024-10-25 DOI: 10.1038/s44160-024-00673-8

Kai-Liang Tao, Xing Wang, Huan Liu, Wen-Qing Chen, Yi Sun, Yun-Qian Zhang, Yu-Xi Li, Zhen-Yu Wang, Yang Ye, Hui Xu, Lefu Lan, Hui-Xiong Dai

{"title":"Multisite modifications of arenes using ketones as removable handles enabled by Pd and norbornene cooperative catalysis","authors":"Kai-Liang Tao, Xing Wang, Huan Liu, Wen-Qing Chen, Yi Sun, Yun-Qian Zhang, Yu-Xi Li, Zhen-Yu Wang, Yang Ye, Hui Xu, Lefu Lan, Hui-Xiong Dai","doi":"10.1038/s44160-024-00673-8","DOIUrl":"10.1038/s44160-024-00673-8","url":null,"abstract":"Natural products serve as crucial sources for new drugs and play an indispensable role in drug discovery. Late-stage functionalization of natural products is an efficient method for diversifying their structures, fine-tuning their biological properties and rapidly constructing molecular libraries. Polysubstituted arenes serve as structural cores in pharmaceuticals derived from natural products. However, programmable multisite arene modification remains a largely unmet challenge. Here, using commercially available and easy-to-synthesize aryl ketones as substrates, we present the programmable multifunctionalization of natural products via a palladium- and norbornene-catalysed Catellani-type reaction. Given the ease of installing an acyl group and using it as a relay, this protocol enables the incorporation of a variety of bioactive molecules into natural products via successive acylation and deacylation processes. Furthermore, this strategy was applied to the construction of a molecular library based on dehydroabietic acid. Multiple molecules with substantially increased activity were obtained through antimicrobial activity screening. Polysubstituted arenes are ubiquitous structural cores in natural products and drugs but their synthesis through programmable arene modification remains a challenge. Now, a palladium- and norbornene-catalysed Catellani-type reaction of aryl ketones, through successive acylation and deacylation, allows the synthesis of polysubstituted arenes.","PeriodicalId":74251,"journal":{"name":"Nature synthesis","volume":"4 2","pages":"209-218"},"PeriodicalIF":0.0,"publicationDate":"2024-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143397416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Predicting enantioselectivity for diverse substrates 预测不同底物的对映选择性

Nature synthesis Pub Date : 2024-10-25 DOI: 10.1038/s44160-024-00683-6

Alison Stoddart

引用次数: 0

Reshaping amino acids 重塑氨基酸

Nature synthesis Pub Date : 2024-10-23 DOI: 10.1038/s44160-024-00676-5

Jingyang Qin, Christopher J. Teskey

引用次数: 0

Polyhedral expansion of closo-hexaboranes 闭己硼烷的多面体扩展

Nature synthesis Pub Date : 2024-10-21 DOI: 10.1038/s44160-024-00680-9

Alexandra R. Groves

引用次数: 0

Designing highly delocalized solitons by harnessing the structural parity of π-conjugated polymers 利用π共轭聚合物的结构宇称设计高度离域孤子

Nature synthesis Pub Date : 2024-10-16 DOI: 10.1038/s44160-024-00665-8

Kalyan Biswas, Jesús Janeiro, Aurelio Gallardo, Marco Lozano, Ana Barragán, Berta Álvarez, Diego Soler-Polo, Oleksandr Stetsovych, Andrés Pinar Solé, Koen Lauwaet, José M. Gallego, Dolores Pérez, Rodolfo Miranda, José I. Urgel, Pavel Jelínek, Diego Peña, David Écija

{"title":"Designing highly delocalized solitons by harnessing the structural parity of π-conjugated polymers","authors":"Kalyan Biswas, Jesús Janeiro, Aurelio Gallardo, Marco Lozano, Ana Barragán, Berta Álvarez, Diego Soler-Polo, Oleksandr Stetsovych, Andrés Pinar Solé, Koen Lauwaet, José M. Gallego, Dolores Pérez, Rodolfo Miranda, José I. Urgel, Pavel Jelínek, Diego Peña, David Écija","doi":"10.1038/s44160-024-00665-8","DOIUrl":"10.1038/s44160-024-00665-8","url":null,"abstract":"π-Conjugated polymers are a class of materials featuring an alternation of single and double bonds along their backbone, a configuration that can result in delocalized π-electrons. The unique electronic structure of these polymers makes them vital in applications such as organic electronics, solar cells and light-emitting diodes. A key feature in such materials is the emergence of topological quasiparticles, termed solitons, which are crucial for their observed high electrical conductivity. By using on-surface synthesis, we present a chemical reaction based on the regio- and stereoselective coupling of indenyl moieties for fabricating π-conjugated acenoindenylidene polymers, which feature a longitudinal polyacetylene backbone, on a Au(111) surface. The relationship between structural parity and electronic properties is investigated. We discover that odd-membered polymers exhibit an in-gap soliton state, which, due to their low bandgaps, spatially extends several nanometres along the longitudinal polyacetylene backbone. Our findings pave the way for the design of π-conjugated polymers that are able to host intrinsic solitons through chemical design by exploiting structural parity, without the need for external doping. An on-surface synthetic route for the regio- and stereoselective coupling of indenyl moieties, affording the design of π-conjugated acenoindenylidene polymers on Au(111), is reported. The relationship between the structural parity of the polymers and their electronic properties reveals the emergence of highly delocalized soliton quasiparticles in odd-membered polymers.","PeriodicalId":74251,"journal":{"name":"Nature synthesis","volume":"4 2","pages":"233-242"},"PeriodicalIF":0.0,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143397419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reproducibility in automated chemistry laboratories using computer science abstractions 利用计算机科学抽象技术实现自动化化学实验室的可重复性

Nature synthesis Pub Date : 2024-10-10 DOI: 10.1038/s44160-024-00649-8

Richard B. Canty, Milad Abolhasani

{"title":"Reproducibility in automated chemistry laboratories using computer science abstractions","authors":"Richard B. Canty, Milad Abolhasani","doi":"10.1038/s44160-024-00649-8","DOIUrl":"10.1038/s44160-024-00649-8","url":null,"abstract":"While abstraction is critical for the transferability of automated laboratory science in (bio)chemical and materials sciences, its improper implementation is a technical debt taken against the reproducibility of experimental results. Over the decades, computer science has developed guidelines and strategies for how abstractions are captured in programming languages—particularly concerning the substitutability of implementations of abstracted ideas and the clear definition of the contexts in which abstractions are used. However, few programming languages developed for automated experiments fully leverage the wisdom learned in computer science. To achieve collaborative sharing of scientific knowledge via automated laboratories, the way that experimental protocols are codified and interpreted by machine agents must use abstractions responsibly and with reproducibility, rather than solely transferability, at its core. This Review discusses how computer science principles of abstraction can be translated to create more reproducible automation as an enabler for the acceleration of collaborative research with self-driving laboratories. Digital workflow representations in automated and autonomous chemistry laboratories can achieve transferability by using abstract concepts. However, such abstractions must abide by certain rules to ensure reproducibility. Lessons learned from computer science for responsible abstraction are translated into an automated chemistry laboratory context to guide digital workflow development towards reproducibility.","PeriodicalId":74251,"journal":{"name":"Nature synthesis","volume":"3 11","pages":"1327-1339"},"PeriodicalIF":0.0,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142596131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0