Medicine international最新文献_第7页

Syncope in the setting of trifascicular block and retrograde concealed conduction: A case report. 三筋膜阻滞和逆行隐蔽传导时的晕厥：病例报告。

Medicine international Pub Date : 2023-11-23 eCollection Date: 2023-11-01 DOI: 10.3892/mi.2023.124

Dimitrios Sfairopoulos, Christos S Konstantinou, Panagiotis Korantzopoulos

引用次数: 0

Ameloblastic fibro‑odontoma in the posterior mandible: A case report. 下颌后部的釉质纤维牙瘤：病例报告

Medicine international Pub Date : 2023-11-20 eCollection Date: 2023-11-01 DOI: 10.3892/mi.2023.123

Mahima Goel, Ali Qamar, Mimansa Daftary, Sujata Rajesh Chhabile, Shruti Pundkar, Manish Sharma

{"title":"Ameloblastic fibro‑odontoma in the posterior mandible: A case report.","authors":"Mahima Goel, Ali Qamar, Mimansa Daftary, Sujata Rajesh Chhabile, Shruti Pundkar, Manish Sharma","doi":"10.3892/mi.2023.123","DOIUrl":"https://doi.org/10.3892/mi.2023.123","url":null,"abstract":"Ameloblastic fibro-odontoma (AFO) is a rare, slow-growing neoplastic lesion classified as a benign, epithelial odontogenic mesenchymal tumor. This tumor exhibits histological features characteristic of both ameloblastic fibromas and complex odontomas. The clinical manifestation of AFO is typically characterized by the asymptomatic enlargement of the jawbones. Radiographically, it presents as a distinct radiolucent region, indicating the presence of radiopaque substances with varying degrees of irregularities in size and morphology. Standard therapeutic intervention involves enucleation. Despite its benign nature, AFO can cause significant morbidity if left untreated. Therefore, prompt diagnosis and appropriate management are essential to ensure optimal patient outcomes. The present study describes the case (clinical presentation and management) of an 18-year-old male patient with an AFO lesion located in the posterior mandible. This particular case was treated with conservative measures involving surgical enucleation along with the extraction of the impacted tooth and the curettage of residual bone.","PeriodicalId":74161,"journal":{"name":"Medicine international","volume":"3 6","pages":"63"},"PeriodicalIF":0.0,"publicationDate":"2023-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10704407/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138811760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Corrigendum] Stormorken syndrome caused by STIM1 mutation: A case report and literature review [更正] STIM1 基因突变导致的斯托莫肯综合征：病例报告和文献综述

Medicine international Pub Date : 2023-11-20 DOI: 10.3892/mi.2023.122

Wenqiang Sun, Jinhui Hu, Mengzhao Li, Xueping Zhu

引用次数: 0

Carotid artery stenting and endarterectomy surgery techniques: A 30‑year time‑lapse 颈动脉支架和内膜切除手术技术：30年的时间回顾

Medicine international Pub Date : 2023-11-16 DOI: 10.3892/mi.2023.121

P. Nana, Konstantinos Spanos, G. Kouvelos, V. Georgakopoulou, Ioannis G. Lempesis, N. Trakas, P. Sklapani, Konstantinos Paterakis, George Fotakopoulos, Alexandros Brotis

引用次数: 0

Pleomorphic giant cell carcinoma of the prostate: A case report and mini‑review of the literature 前列腺多形性巨细胞癌1例报告及文献复习

Medicine international Pub Date : 2023-11-10 DOI: 10.3892/mi.2023.120

Saman Fakhralddin, Rawa Ali, Ari Abdullah, Farman Faraj, Dlsoz Hussein, Shvan Mohammed, Berun Abdalla, Fahmi Kakamad, Hawbash Rahim

{"title":"Pleomorphic giant cell carcinoma of the prostate: A case report and mini‑review of the literature","authors":"Saman Fakhralddin, Rawa Ali, Ari Abdullah, Farman Faraj, Dlsoz Hussein, Shvan Mohammed, Berun Abdalla, Fahmi Kakamad, Hawbash Rahim","doi":"10.3892/mi.2023.120","DOIUrl":"https://doi.org/10.3892/mi.2023.120","url":null,"abstract":"Pleomorphic giant cell carcinoma (PGCC) is an exceptionally uncommon form of prostate adenocarcinoma. It consists of unusually large and irregular cells with varied nuclei. The present study describes a rare case of prostatic PGCC. A 65‑year‑old male patient presented to the urology clinic with severe dysuria, nocturia, and frequent, urgent, and difficult urination for a period of 3 months. Pelvic magnetic resonance imaging revealed a large pelvic mass. A prostate biopsy was performed, and immunohistochemical analysis revealed positivity for the pan‑epithelial markers, AE1/AE3, alpha‑methyl acyl‑CoA racemase, and focally for sphingolipid activator protein‑2. While waiting for his pathology report, the patient's condition deteriorated, and he was diagnosed with intestinal obstruction. The patient underwent laparotomy and end colostomy. Later, he developed severe sepsis and wound dehiscence. After 2 weeks, the patient succumbed due to multiorgan failure. Prostatic PGCC cases are frequently associated with previous chemo‑, hormone, or radiation therapy. Prior to the diagnosis of PGCC, it is critical to rule out urothelial carcinoma. Early recognition of this rare condition can lead to more effective therapy. Prostatic PGCC is extremely rare. Immunohistochemistry for prostatic markers, such as prostate‑specific membrane antigen, prostate‑specific antigen, NK3 homeobox 1 and androgen receptor, can be used to confirm its origin.","PeriodicalId":74161,"journal":{"name":"Medicine international","volume":"90 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135091746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinicopathological significance and prognostic implications of Ube2v1 expression in colorectal cancer. 结直肠癌中Ube2v1表达的临床病理意义及预后意义

Medicine international Pub Date : 2023-10-31 eCollection Date: 2023-11-01 DOI: 10.3892/mi.2023.119

Qiang Ma, Jin Bao, Naiying Sun, Xingjie Yang, Li Liu, Ying Chen, Wenjun Guo, Lixiang Gao

{"title":"Clinicopathological significance and prognostic implications of Ube2v1 expression in colorectal cancer.","authors":"Qiang Ma, Jin Bao, Naiying Sun, Xingjie Yang, Li Liu, Ying Chen, Wenjun Guo, Lixiang Gao","doi":"10.3892/mi.2023.119","DOIUrl":"10.3892/mi.2023.119","url":null,"abstract":"The present study aimed to investigate the expression of ubiquitin-conjugating enzyme E2 variant 1 (Ube2v1) in colorectal cancer (CRC) and its clinical significance. The differential expression of Ube2v1 in CRC tissues and normal intestinal tissues, as well as the association between Ube2v1 expression and the prognosis of patients with CRC were analyzed using bioinformatics analyses. TIMER database analysis revealed higher Ube2v1 expression in CRC tissues than in normal intestinal tissues. Cancerous and normal tissues collected retrospectively from 37 cases of CRC between July, 2022 and June, 2023 were analyzed for Ube2v1 expression using immunohistochemistry, and the associations between Ube2v1 expression and the clinical pathological features of patients with CRC were analyzed. Ube2v1 expression was associated with lymph node metastasis in patients with CRC (P<0.05). However, bioinformatics analysis using the GEPIA2 and HPA database revealed that Ube2v1 was not associated with the overall survival of patients with CRC. On the whole, the present study demonstrates that due to its high expression and association with lymph node metastasis, Ube2v1 may serve as a potential target for the treatment of CRC.","PeriodicalId":74161,"journal":{"name":"Medicine international","volume":"3 6","pages":"59"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10636623/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89720997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Weekly phototherapy is an effective therapy for patients with vitiligo. 每周光疗是白癜风患者的有效治疗方法。

Medicine international Pub Date : 2023-10-30 eCollection Date: 2023-11-01 DOI: 10.3892/mi.2023.118

Jing-Yu Wang, Shu-Lan Yao, Xin-Yi Hou, Hai-Lu Xiao, Bin Lu

引用次数: 0

Issues with the targeted therapy of non‑small cell lung cancer with thyroid metastases: A case report. 甲状腺转移的非小细胞肺癌癌症靶向治疗的问题：一例病例报告。

Medicine international Pub Date : 2023-10-17 eCollection Date: 2023-11-01 DOI: 10.3892/mi.2023.117

Ertugrul Bayram, Tugba Toyran, Burak Güney, Aysun Hatice Uguz, Derya Gümürdülü, Semra Paydas

引用次数: 0

Castleman disease: Experience from a single institution. Castleman病：单一机构的经验。

Medicine international Pub Date : 2023-10-06 eCollection Date: 2023-11-01 DOI: 10.3892/mi.2023.116

Sherry S Abraham, Geetha Narayanan, Sugeeth Mangalapilly Thambi, Jayasudha Arundhathi Vasudevan, Deepa Susan Joy Philip, Prakash N Purushothaman, Sreejith G Nair, Rekha Nair

{"title":"Castleman disease: Experience from a single institution.","authors":"Sherry S Abraham, Geetha Narayanan, Sugeeth Mangalapilly Thambi, Jayasudha Arundhathi Vasudevan, Deepa Susan Joy Philip, Prakash N Purushothaman, Sreejith G Nair, Rekha Nair","doi":"10.3892/mi.2023.116","DOIUrl":"https://doi.org/10.3892/mi.2023.116","url":null,"abstract":"Castleman disease (CD) describes a group of rare heterogeneous lymphoproliferative disorders characterized by enlarged hyperplastic lymph nodes. It is classified into unicentric CD (UCD) and multicentric CD (MCD). The present retrospective study examined the data of 11 patients with CD diagnosed and treated at a tertiary cancer center from 2017 to 2022. The median age of the study group was 41 years (range, 24 to 68 years). There were 8 males and 3 females. In total, 7 patients were diagnosed with UCD and 4 patients with MCD. The hyaline-vascular variant was the most common histology in both UCD and MCD. Among the 7 patients with UCD, 5 patients underwent excision, 1 patient underwent debulking followed by radiotherapy and 1 patient received single agent rituximab. Of the patients with UCD, 6 had a complete response (CR) and 1 patient had a partial response (PR). All 4 patients with MCD received systemic treatment, which included single agent rituximab (2 patients), rituximab, cyclophosphamide, doxorubicin, vincristine and prednisolone (RCHOP) (1 patient) and CHOP (1 patient). Among the patients with MCD, 1 patient attained a CR, 2 patients had a PR and 1 patient succumbed. The 3-year survival rate for the study population was 91%. In summary, CD is a rare disease occurring in immunodeficient patients. UCD is more common and is associated with better outcomes. Surgery is the mainstay of management in UCD whereas MCD requires combination chemotherapy.","PeriodicalId":74161,"journal":{"name":"Medicine international","volume":"3 6","pages":"56"},"PeriodicalIF":0.0,"publicationDate":"2023-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620848/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71489736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy of increasing levels of exposure therapy in the treatment of maladaptive behaviors and anxiety. 提高暴露治疗水平对适应不良行为和焦虑的疗效。

Medicine international Pub Date : 2023-10-03 eCollection Date: 2023-09-01 DOI: 10.3892/mi.2023.115

Fatih Bal

{"title":"Efficacy of increasing levels of exposure therapy in the treatment of maladaptive behaviors and anxiety.","authors":"Fatih Bal","doi":"10.3892/mi.2023.115","DOIUrl":"https://doi.org/10.3892/mi.2023.115","url":null,"abstract":"The present study examined the effectiveness of increasing levels of exposure therapy, which is applied for the treatment of maladaptive behaviors and anxiety. A total of 16 sessions were applied to the study group in the experimental group three times a week for 10 weeks. Patients aged ≥18 years whom the referring clinician evaluated as meeting the criteria for the Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-V-TR) Generalized Anxiety Disorder were included in the study. For the control group, demographic characteristics and Spielberger's State-Trait Anxiety Inventory were applied in the first session, followed by Spielberger's State-Trait Anxiety Inventory as a post-test and follow-up. Electroencephalography (EEG) recordings of the study group were obtained at the cortical level. Electrodes for EEG measurements were recorded using the International 10/20 Electrode Placement System. EEG data were obtained using the EEG Analysis Program software. Following the data collection phase, all data were entered into cells based on items using SPSS 25 software. When the findings obtained in the study were examined, it was determined that the increasing levels of exposure and behavioral therapy applied for maladaptive anxiety decreased the anxiety levels compared to those before therapy. This finding can be interpreted as that the cortical function-oriented application method for anxiety effectively reduced the anxiety levels of the study group. However, EEG asymmetry revealed a change in the data before and after the application. These findings demonstrate that the application affects the EEG asymmetry changes at the cortical level.","PeriodicalId":74161,"journal":{"name":"Medicine international","volume":"3 5","pages":"55"},"PeriodicalIF":0.0,"publicationDate":"2023-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580115/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49685852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0