Medicine internationalPub Date : 2024-10-10eCollection Date: 2024-11-01DOI: 10.3892/mi.2024.199
Alexandros G Brotis, George Fotakopoulos, Vasiliki Epameinondas Georgakopoulou, Adamantios Kalogeras, Theodosis Spiliotopoulos, Ioannis Ioannidis, Kostas N Fountas
{"title":"Determination of a 'point of no return' in refractory chronic subdural hematomas: A case report and review of the literature.","authors":"Alexandros G Brotis, George Fotakopoulos, Vasiliki Epameinondas Georgakopoulou, Adamantios Kalogeras, Theodosis Spiliotopoulos, Ioannis Ioannidis, Kostas N Fountas","doi":"10.3892/mi.2024.199","DOIUrl":"10.3892/mi.2024.199","url":null,"abstract":"<p><p>Recurrence following the surgical evacuation of a chronic subdural hematoma (CSDH) occurs in up to 33% of cases. Several clinical and radiologic factors have been identified that are associated with the recurrence of hematoma. However, the optimal treatment for recurrent CSDH has not yet been determined. The present study, based on a case report, reviews the predictors and treatment options for refractory CSDHs. An 85-year-old male patient presented with a symptomatic bilateral CSDH. The hematoma was initially removed through a burr hole and closed drainage system, resulting in clinical improvement and in the radiographic resolution of the hematoma. At the first recurrence, steroids were administered and the hematoma was re-evacuated. After 1 month, the patient returned comatose due to a massive right subdural hematoma and was treated with an ipsilateral craniotomy and a membranectomy. After 2 days, the patient succumbed due to massive intraparenchymal bleeding. The treatment of refractory CSDHs is challenging. The failure of brain re-expansion and senile atrophy appear to be the key predictors of recurrence. Patients who are at high-risk need to be identified promptly and treated with a multidisciplinary approach that considers adjuvant medications, middle meningeal artery embolization and repeat hematoma evacuation, probably with a membranectomy and an endoscope.</p>","PeriodicalId":74161,"journal":{"name":"Medicine international","volume":"4 6","pages":"75"},"PeriodicalIF":0.0,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11526243/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142559647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medicine internationalPub Date : 2024-10-09eCollection Date: 2024-11-01DOI: 10.3892/mi.2024.197
Carlos Abraham Orpinel-González, Marcos Iglesias-González, Joel Herrera-Loya, Carlos Arturo Martínez-Méndez, Aaron Alberto Ramírez-Torres, Raúl Gerardo Ramírez-Medina
{"title":"Successful treatment of osteosarcoma in a pregnant woman with survival of the gestational product: A case report and literature review.","authors":"Carlos Abraham Orpinel-González, Marcos Iglesias-González, Joel Herrera-Loya, Carlos Arturo Martínez-Méndez, Aaron Alberto Ramírez-Torres, Raúl Gerardo Ramírez-Medina","doi":"10.3892/mi.2024.197","DOIUrl":"10.3892/mi.2024.197","url":null,"abstract":"<p><p>Osteosarcoma (OS) is the most prevalent bone neoplasm of mesenchymal origin, accounting for 20% of all bone tumors worldwide. It mainly affects the marrow of long bones, and its diagnosis is more common among adolescents and the geriatric population. Histologically, it is characterized by high cellular variability, abundant osteoid and fibrotic material. In the early stages, it presents with only local symptoms such as pain, edema and limited joint mobility. This neoplasm, when detected promptly, is associated with a favorable prognosis and can be effectively treated through surgical removal and adjuvant therapy. The development of tumors in pregnant women is rare, and the occurrence of osteosarcoma is even more exceptional, with only 10 cases documented in the literature. Given its rarity, the present study describes the case of a female patient with OS diagnosed in the first trimester of pregnancy, where the patient responded well to treatment, resulting in no adverse effects on the pregnancy outcome.</p>","PeriodicalId":74161,"journal":{"name":"Medicine international","volume":"4 6","pages":"73"},"PeriodicalIF":0.0,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11526288/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142560344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medicine internationalPub Date : 2024-10-09eCollection Date: 2024-11-01DOI: 10.3892/mi.2024.198
Anita Katić, Nermina Rizvanović
{"title":"Predictive significance of hypertension in the incidence of complications in critically ill patients with COVID‑19: A retrospective cohort study.","authors":"Anita Katić, Nermina Rizvanović","doi":"10.3892/mi.2024.198","DOIUrl":"10.3892/mi.2024.198","url":null,"abstract":"<p><p>The association between hypertension as a pre-existing comorbidity and the severe form of coronavirus disease 2019 (COVID-19) remains unclear due to the contradictory results of previously published studies. The present study evaluated the predictive significance of hypertension in the incidence of complications among critically ill patients with COVID-19. The present study included 372 critically ill adults with COVID-19 pneumonia, hospitalized between January 1 and December 31, 2021. The study cohort was divided into the hypertension group (HTA group), which included 245 patients with a history of hypertension, or a non-HTA group (control group), which included 127 patients without hypertension. The incidence of complications was retrospectively extracted from medical records and compared between groups. Multivariate regression analysis (adjusted for potential confounders) and receiver operating characteristic (ROC) curve analysis determined the predictive significance of hypertension on the incidence of complications. The patients in the HTA group were more likely to receive invasive mechanical ventilation [odds ratio (OR), 1.696; P<0.02], develop sepsis (OR, 1.807; P<0.01) and develop complications (OR, 3.101; P<0.001). Hypertension was an independent positive predictor for invasive mechanical ventilation [area under the curve (AUC), 0.67; positive predictive value (PPV), 71.7%; P<0.05], sepsis (AUC, 0.69; PPV, 77.5%; P<0.026) and total complications per patient (AUC, 0.71; PPV, 81.4%; P<0.001). On the whole, the data of the present study indicate that a history of hypertension should be considered as an independent clinical predictor of a higher incidence of complications in critically ill patients with COVID-19. Patients with pre-existing hypertension and a diagnosis of COVID-19 require timely identification, additional attention and treatment to avoid a critical course and help improve outcomes.</p>","PeriodicalId":74161,"journal":{"name":"Medicine international","volume":"4 6","pages":"74"},"PeriodicalIF":0.0,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11526207/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142559648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohamed Montasr, George Fotakopoulos, V. Georgakopoulou, Ourania Fotakopoulou, N. Trakas, P. Sklapani, Kostas N. Fountas
{"title":"Association between polymorphisms of DNA repair genes and intracranial aneurysms: A systematic review and meta‑analysis","authors":"Mohamed Montasr, George Fotakopoulos, V. Georgakopoulou, Ourania Fotakopoulou, N. Trakas, P. Sklapani, Kostas N. Fountas","doi":"10.3892/mi.2024.183","DOIUrl":"https://doi.org/10.3892/mi.2024.183","url":null,"abstract":"","PeriodicalId":74161,"journal":{"name":"Medicine international","volume":"61 22","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141807215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Moosa Allawati, Yahya Al-Kindi, Said Al Jaadi, Tariq Al-Saadi
{"title":"Pediatric TBI: Direct admissions vs. secondary referrals to a hospital: A single‑center, retrospective study","authors":"Moosa Allawati, Yahya Al-Kindi, Said Al Jaadi, Tariq Al-Saadi","doi":"10.3892/mi.2024.182","DOIUrl":"https://doi.org/10.3892/mi.2024.182","url":null,"abstract":"","PeriodicalId":74161,"journal":{"name":"Medicine international","volume":"47 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141810475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hao Qian, Guohuan Ying, Haifeng Xu, Shangyu Wang, Bing Wu, Xin Wang, Hongdan Qi, Mingying He, M. J. Ud Din, Tingting Huang, Yimei Wu, Gang Zhang
{"title":"Clinical and genetic analysis of children with glucose transporter type 1 deficiency syndrome","authors":"Hao Qian, Guohuan Ying, Haifeng Xu, Shangyu Wang, Bing Wu, Xin Wang, Hongdan Qi, Mingying He, M. J. Ud Din, Tingting Huang, Yimei Wu, Gang Zhang","doi":"10.3892/mi.2024.181","DOIUrl":"https://doi.org/10.3892/mi.2024.181","url":null,"abstract":"","PeriodicalId":74161,"journal":{"name":"Medicine international","volume":"120 51","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141821048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Song Giang Tran, Thi Kieu My Tran, Tan Sang Nguyen, Minh Phuong Vu
{"title":"Early detection of resistance to dual antiplatelet therapy in patients who have undergone percutaneous coronary intervention using the VerifyNow test and associated factors","authors":"Song Giang Tran, Thi Kieu My Tran, Tan Sang Nguyen, Minh Phuong Vu","doi":"10.3892/mi.2024.180","DOIUrl":"https://doi.org/10.3892/mi.2024.180","url":null,"abstract":"","PeriodicalId":74161,"journal":{"name":"Medicine international","volume":" 87","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141824814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
George Fotakopoulos, Alexandros G. Brotis, Ourania Fotakopoulou, C. Gatos, Konstantinos Mantzarlis, V. Georgakopoulou, P. Sklapani, N. Trakas, Kostas N. Fountas
{"title":"Prevalence of ACA variations: A systematic review and meta‑analysis","authors":"George Fotakopoulos, Alexandros G. Brotis, Ourania Fotakopoulou, C. Gatos, Konstantinos Mantzarlis, V. Georgakopoulou, P. Sklapani, N. Trakas, Kostas N. Fountas","doi":"10.3892/mi.2024.178","DOIUrl":"https://doi.org/10.3892/mi.2024.178","url":null,"abstract":"","PeriodicalId":74161,"journal":{"name":"Medicine international","volume":"26 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141647829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Saman Fakhralddin, Rawa Ali, Sami Omar, Rebaz Ali, Bryar Mohammed, Rawa Karim, Hiwa Abdullah, Karukh Mohammed, Shvan H. Mohammed, Sasan Ahmed, Fahmi H. Kakamad
{"title":"Intratesticular prepubertal‑type mature teratoma in an infant: A case report and mini‑review of the literature","authors":"Saman Fakhralddin, Rawa Ali, Sami Omar, Rebaz Ali, Bryar Mohammed, Rawa Karim, Hiwa Abdullah, Karukh Mohammed, Shvan H. Mohammed, Sasan Ahmed, Fahmi H. Kakamad","doi":"10.3892/mi.2024.177","DOIUrl":"https://doi.org/10.3892/mi.2024.177","url":null,"abstract":"","PeriodicalId":74161,"journal":{"name":"Medicine international","volume":"10 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141648158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}