Medicine international最新文献_第4页

Rehabilitation management of patients with spinal tuberculosis (Review) 脊柱结核患者的康复管理（回顾）

Medicine international Pub Date : 2024-04-04 DOI: 10.3892/mi.2024.152

Jaouher Dhouibi, A. Kalai, A. Chaabeni, Ahlem Aissa, Z. Ben Salah Frih, A. Jellad

{"title":"Rehabilitation management of patients with spinal tuberculosis (Review)","authors":"Jaouher Dhouibi, A. Kalai, A. Chaabeni, Ahlem Aissa, Z. Ben Salah Frih, A. Jellad","doi":"10.3892/mi.2024.152","DOIUrl":"https://doi.org/10.3892/mi.2024.152","url":null,"abstract":"Spinal tuberculosis (ST) is a serious condition and a global health concern, accounting for a significant portion of musculoskeletal tuberculosis cases. It can lead to sever spinal and neurological complications. The management of ST involves a multidisciplinary approach, including medical treatment, surgery and rehabilitation. Rehabilitation is crucial through the course of the disease's and is tailored for each stage according to the patients' complaints, and clinical and functional complications. In the case of neurological issues due to spinal compression, rehabilitation aims at overcoming bed confinement complications, involving mobilization techniques, strengthening exercises and related vesico-sphincter disorders (urodynamics, catheterizing). The role of rehabilitation for the management of pain in patients with ST is based on bracing (restricting movements and relieving the pressure on harmed structures), and analgesic physical means (electrical stimulation and massage techniques). Several rehabilitation options may be used to address musculoskeletal complications. Range of motion exercises, muscle strengthening, and posture and balance correction using sensory perception and proprioception techniques, are commonly involved. Cardiorespiratory reconditioning is required to improve respiratory function, walking ability and cardiovascular endurance. Ultimately, rehabilitation allows for the minimization of disability and the prevention of the loss of autonomy, particularly in elderly patients. The advantage of the rehabilitation approach is its multi-optional characteristics including physical therapy, occupational therapy, ergonomic advices and assistive equipment. Despite its crucial role, rehabilitation remains understudied in the management of ST. Thus, the present mini-review aimed to address the rehabilitation options for the clinical features and complications of ST, according to the course of the disease.","PeriodicalId":74161,"journal":{"name":"Medicine international","volume":"16 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140741154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Thyroid abscess, an uncommon diagnosis: A case report and mini‑review of the literature 甲状腺脓肿，一种不常见的诊断：病例报告和文献综述

Medicine international Pub Date : 2024-04-04 DOI: 10.3892/mi.2024.153

Patricia Urbón-Sánchez, F. Mendoza-Moreno, Sofía Sánchez De Toca‑Gómez, Félix Mañes-Jiménez, Rubén Jiménez-Martín, Marta Bru-Aparicio, P. Laguna-Hernández, Yousef Allaoua-Moussaoui, Sonia Soto-Schutte, Ana Quiroga-Valcárcel, M. Díez-Alonso, I. Lasa Unzué, A. Gutiérrez-Calvo

{"title":"Thyroid abscess, an uncommon diagnosis: A case report and mini‑review of the literature","authors":"Patricia Urbón-Sánchez, F. Mendoza-Moreno, Sofía Sánchez De Toca‑Gómez, Félix Mañes-Jiménez, Rubén Jiménez-Martín, Marta Bru-Aparicio, P. Laguna-Hernández, Yousef Allaoua-Moussaoui, Sonia Soto-Schutte, Ana Quiroga-Valcárcel, M. Díez-Alonso, I. Lasa Unzué, A. Gutiérrez-Calvo","doi":"10.3892/mi.2024.153","DOIUrl":"https://doi.org/10.3892/mi.2024.153","url":null,"abstract":"Thyroid abscess is a rare entity, commonly experienced by immunocompromised patients, or those who have anatomical abnormalities or a pre-existing thyroid disease. An early diagnosis continued by treatment with antibiotics and drainage of the abscess is the recommended therapeutic strategy for such cases. The present study describes a clinical case of this rare event, and also provides a brief literature review. The present study describes the case of a 48-year-old healthy male with no medical antecedents, apart from acute prostatitis treated with antibiotics for 6 days prior, who visited the Emergency Department of the authors' hospital with neck pain and progressive swelling of the mass. Diagnostic imaging confirmed the authors' suspicion of an abscess and revealed the lesion displacing the airway to the contralateral side. This restricted the mobility of the neck of the patient. As an emergency measure, the patient was then taken to the operating room for a neck examination. A hemithyroidectomy was finally performed. Following a prolonged hospital duration, he was discharged from the hospital and his recovery was uneventful without any voice alterations, hypocalcemia or recurrence.","PeriodicalId":74161,"journal":{"name":"Medicine international","volume":"38 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140743481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Labor management and neonatal outcomes in cardiotocography categories II and III (Review) 第二和第三类心动图的分娩管理和新生儿预后（综述）

Medicine international Pub Date : 2024-04-01 DOI: 10.3892/mi.2024.151

Panagiotis Tsikouras, Efthimios Oikonomou, A. Bothou, Dimimitrios Kyriakou, Theopi Nalbanti, Sotirios Andreou, Angelos Daniilidis, Panagiotis Peitsidis, K. Nikolettos, Georgios Iatrakis, N. Nikolettos

{"title":"Labor management and neonatal outcomes in cardiotocography categories II and III (Review)","authors":"Panagiotis Tsikouras, Efthimios Oikonomou, A. Bothou, Dimimitrios Kyriakou, Theopi Nalbanti, Sotirios Andreou, Angelos Daniilidis, Panagiotis Peitsidis, K. Nikolettos, Georgios Iatrakis, N. Nikolettos","doi":"10.3892/mi.2024.151","DOIUrl":"https://doi.org/10.3892/mi.2024.151","url":null,"abstract":"The safe care of both mothers and fetuses during labor is a primary goal of all health professionals. The assessment of fetal oxygenation and well-being is a key aspect of perinatal care provided. Fetal heart rate (FHR) auscultation became part of daily obstetric practice in a number of countries during the 20th century and remains a key method of fetal monitoring, particularly in low-risk pregnancies. Cardiotocography (CTG) is the continuous monitoring and recording of the FHR and uterine myometrial activity, making it possible to assess the fetal condition. It therefore plays a critical role in the detection of fetal hypoxia during labor, a condition directly related to short- and long-term complications in the newborn. Herein, particular reference is made to the management of CTG category II and III standards, as well as to the handling of childbirth. In addition, specific FHR patterns are associated with immediate neonatal outcomes based on updated studies conducted worldwide. Finally, the prognostic significance of CTG and its potential as a prospective avenue for further investigation are also highlighted herein. Given that the misinterpretation of CTG findings is the most common cause of medical-legal responsibility, this knowledge field requires more emphasis and attention. The aim of the present review was to further deepen the knowledge on issues that mainly concern the safety and monitoring of pregnant women and fetuses during childbirth.","PeriodicalId":74161,"journal":{"name":"Medicine international","volume":"50 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140790752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bilateral obstructive uropathy and severe renal dysfunction associated with large prolapsed pedunculated submucosal leiomyoma of the uterus misdiagnosed as an intracervical fibroid: Report of a very rare case and a mini‑review of the literature 被误诊为宫颈内肌瘤的巨大脱垂有蒂子宫粘膜下子宫肌瘤引发双侧梗阻性尿路病变和严重肾功能障碍：一例罕见病例的报告和文献综述

Medicine international Pub Date : 2024-03-27 DOI: 10.3892/mi.2024.150

Efthymia Thanasa, Anna Thanasa, Vasiliki Grapsidi, E. Xydias, Evangelos Kamaretsos, A. Ziogas, Ioannis Paraoulakis, E. Simopoulou, Maria Mousia, I. Thanasas

引用次数: 0

Chemoprophylaxis of precancerous lesions in patients who are at a high risk of developing colorectal cancer (Review) 对大肠癌高危患者的癌前病变进行化学预防（综述）

Medicine international Pub Date : 2024-03-27 DOI: 10.3892/mi.2024.149

Nonna Ogurchenok, Konstantin Khalin, Igor Bryukhovetskiy

引用次数: 0

Efficacy of foam sclerotherapy with polidocanol for the management of oral venous malformations 用多聚甲醛泡沫硬化剂治疗口腔静脉畸形的疗效

Medicine international Pub Date : 2024-03-26 DOI: 10.3892/mi.2024.148

Tomoki Kato, Yasuhiro Katayama, S. Fukuhara, Takuma Watanabe, S. Yamanaka, K. Nakao, Naoki Morimoto

引用次数: 0

Elderly patient with unresectable advanced‑stage hepatocellular carcinoma who received atezolizumab plus bevacizumab and achieved a complete response: A case report 无法切除的晚期肝细胞癌老年患者接受阿特珠单抗加贝伐单抗治疗后获得完全缓解：病例报告

Medicine international Pub Date : 2024-03-20 DOI: 10.3892/mi.2024.147

Shuhei Arima, Tatsuo Kanda, Mai Totsuka, Masayuki Honda, Shini Kanezawa, Reina Sasaki-Tanaka, Naoki Matsumoto, Ryota Masuzaki, Hiroaki Yamagami, Masahiro Ogawa, Hirofumi Kogure

引用次数: 0

Severe hepatitis E virus genotype 3b in a patient with alcohol‑associated liver disease: A case report 一名酒精相关性肝病患者的重症戊型肝炎病毒基因 3b 型：病例报告

Medicine international Pub Date : 2024-03-07 DOI: 10.3892/mi.2024.146

Tatsuo Kanda, Shuhei Arima, Reina Sasaki-Tanaka, Mai Totsuka, Masayuki Honda, Ryota Masuzaki, Naoki Matsumoto, Masahiro Ogawa, Masaharu Takahashi, Hiroaki Okamoto, Hirofumi Kogure

{"title":"Severe hepatitis E virus genotype 3b in a patient with alcohol‑associated liver disease: A case report","authors":"Tatsuo Kanda, Shuhei Arima, Reina Sasaki-Tanaka, Mai Totsuka, Masayuki Honda, Ryota Masuzaki, Naoki Matsumoto, Masahiro Ogawa, Masaharu Takahashi, Hiroaki Okamoto, Hirofumi Kogure","doi":"10.3892/mi.2024.146","DOIUrl":"https://doi.org/10.3892/mi.2024.146","url":null,"abstract":". Hepatitis E virus (HEV) infection occasion‑ ally causes acute‑on‑chronic liver failure in patients with alcohol‑associated cirrhosis. These reports have been published mainly from highly HEV genotype 1‑endemic countries. The present study describes the case of a patient with severe HEV genotype 3b infection and alcohol‑associated liver disease. A male patient in his 70s who consumed alcohol, and who had begun consuming alcohol at the age of 12, had high levels of alanine aminotransferase (ALT) and total bilirubin. The peak levels of ALT and total bilirubin were 1,067 IU/l and 26.3 mg/dl, respectively. A computed tomography scan revealed an atrophic liver. Upon admission, both anti‑HEV immunoglobulin A and HEV RNA were positive, and his HEV was genotype 3b. He also had chronic kidney disease, as his estimated glomerular filtration rate was <45 ml/min/1.73 m 2 , and ribavirin could not be used. The abnormal levels of the liver function parameters of the patient gradually improved due to conservative treatment, and he was discharged on day 43. On the whole, the present study demonstrates that careful attention should be paid to patients with viral hepatitis, including hepatitis E, when alcohol‑associated liver disease is present. Novel anti‑HEV drugs need to be developed for severe HEV infections with chronic kidney disease.","PeriodicalId":74161,"journal":{"name":"Medicine international","volume":"10 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140260293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Aging and cancer: Clinical role of tumor markers in the geriatric population (Review) 衰老与癌症：肿瘤标志物在老年人群中的临床作用（综述）

Medicine international Pub Date : 2024-03-06 DOI: 10.3892/mi.2024.145

S. Sundaresan, Palanirasu Rajapriya, SelvarajKaveri Lavanya

{"title":"Aging and cancer: Clinical role of tumor markers in the geriatric population (Review)","authors":"S. Sundaresan, Palanirasu Rajapriya, SelvarajKaveri Lavanya","doi":"10.3892/mi.2024.145","DOIUrl":"https://doi.org/10.3892/mi.2024.145","url":null,"abstract":". Aging, with the progressive deterioration and functional decline of several organ systems, is highly hetero‑ geneous for both between and within individuals. Tumor markers are widely used in clinical practice as a screening test for individuals >50 years of age. More specifically, caring for elderly patients is a public health concern, given the incidence of cancer and its related mortality and morbidity. A multidisci‑ plinary diagnostic procedure known as a geriatric assessment is capable of identifying functional, psychological and physi‑ ological issues that are missed by standard evaluation. The present review focuses on cancers affecting the geriatric population, highlights current opportunities and challenges, and highlights the unmet need for clinically relevant tumor markers in elderly patients with cancer. A comprehensive geriatric examination, including a biological assessment, still requires conveniently available tumor markers and their levels in older populations in order to forecast deterioration or loss of functional balance. These tumor indicators ought to make it possible to track patients using other outcomes, such overall survival and functional impairment. Despite the notable progress made in the understanding of human biology, the mechanisms and networks underlying aging remain largely unknown. In addition, as elderly patients are a highly heterogeneous population, age‑related changes cannot be distinguished solely by chronological age. Strong clinical studies, well‑established protocols and meta‑analyses may contribute to the better utilization of tumor biomarkers in the elderly population. Hence, the present review addresses the effects of aging on tumor markers and the usefulness of tumor marker values for the geriatric population.","PeriodicalId":74161,"journal":{"name":"Medicine international","volume":"67 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140261285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adrenergic receptor system as a pharmacological target in the treatment of epilepsy (Review). 肾上腺素能受体系统作为治疗癫痫的药理靶点（综述）。

Medicine international Pub Date : 2024-02-27 eCollection Date: 2024-03-01 DOI: 10.3892/mi.2024.144

Ercan Ozdemir

{"title":"Adrenergic receptor system as a pharmacological target in the treatment of epilepsy (Review).","authors":"Ercan Ozdemir","doi":"10.3892/mi.2024.144","DOIUrl":"10.3892/mi.2024.144","url":null,"abstract":"Epilepsy is a complex and common neurological disorder characterized by spontaneous and recurrent seizures, affecting ~75 million individuals worldwide. Numerous studies have been conducted to develop new pharmacological drugs for the effective treatment of epilepsy. In recent years, numerous experimental and clinical studies have focused on the role of the adrenergic receptor (AR) system in the regulation of epileptogenesis, seizure susceptibility and convulsions. α1-ARs (α1A, α1B and α1D), α2-ARs (α2A, α2B and α2C) and β-ARs (β1, β2 and β3), known to have convulsant or anticonvulsant effects, have been isolated. Norepinephrine (NE), the key endogenous agonist of ARs, is considered to play a crucial role in the pathophysiology of epileptic seizures. However, the effects of NE on different ARs have not been fully elucidated. Although the activation of some AR subtypes produces conflicting results, the activation of α1, α2 and β receptor subtypes, in particular, produces anticonvulsant effects. The present review focuses on NE and ARs involved in epileptic seizure formation and discusses therapeutic approaches.","PeriodicalId":74161,"journal":{"name":"Medicine international","volume":"4 2","pages":"20"},"PeriodicalIF":0.0,"publicationDate":"2024-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10928664/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140112350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0