{"title":"Application of comprehensive evaluation methods in the clinical efficacy evaluation of traditional Chinese medicine: a narrative review","authors":"Jing Hu, Huina Zhang, Shuo Feng, Bo Li","doi":"10.21037/lcm-21-63","DOIUrl":"https://doi.org/10.21037/lcm-21-63","url":null,"abstract":"","PeriodicalId":74086,"journal":{"name":"Longhua Chinese medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44137820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fu xie theory: a theoretical basis for the future of medicine","authors":"Darong Wu","doi":"10.21037/lcm-2022-01","DOIUrl":"https://doi.org/10.21037/lcm-2022-01","url":null,"abstract":"","PeriodicalId":74086,"journal":{"name":"Longhua Chinese medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45781357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Tung, Nguyen Ngoc Hieu, Vu Van Tuan, Y. Shoyama
{"title":"A narrative review of phytochemical profile of Saffron and principal crocetin glycosides","authors":"N. Tung, Nguyen Ngoc Hieu, Vu Van Tuan, Y. Shoyama","doi":"10.21037/lcm-21-70","DOIUrl":"https://doi.org/10.21037/lcm-21-70","url":null,"abstract":"","PeriodicalId":74086,"journal":{"name":"Longhua Chinese medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47377193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tianyuan Wang, Xuejiao Wang, Shuangshuang He, Ruochong Wang, Qingyun He, Lei Xu, Min Fang, Botan Li
{"title":"Efficacy and safety of auriculotherapy based on syndrome differentiation for constipation vs. western medicine: a systematic review of randomized controlled trials","authors":"Tianyuan Wang, Xuejiao Wang, Shuangshuang He, Ruochong Wang, Qingyun He, Lei Xu, Min Fang, Botan Li","doi":"10.21037/lcm-20-41","DOIUrl":"https://doi.org/10.21037/lcm-20-41","url":null,"abstract":"Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, China; Beijing Institute of Traditional Chinese Medicine, Beijing, China; Beijing Evidence-Based Chinese Medicine Center, Beijing, China; Graduate School, Beijing University of Traditional Chinese Medicine, Beijing, China; Graduate School, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China Contributions: (I) Conception and design: T Wang, B Li; (II) Administrative support: None; (III) Provision of study materials or patients: T Wang; (IV) Collection and assembly of data: T Wang, X Wang, B Li, L Xu, R Wang; (V) Data analysis and interpretation: S He, Q He, M Fang; (VI) Manuscript writing: All authors; (VII) Final approval of manuscript: All authors. Correspondence to: Bo Li. Beijing Hospital of Traditonal Chinese Medicine, Capital Medical University, No. 23 Art Gallery Back Street, Dongcheng District, Beijing 100010, China. Email: libo@bjzhongyi.com.","PeriodicalId":74086,"journal":{"name":"Longhua Chinese medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42255681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Chinese medicine: a gift from the Chinese people to the rest of humanity","authors":"Ramon Ma Calduch Farnòs","doi":"10.21037/lcm-21-24","DOIUrl":"https://doi.org/10.21037/lcm-21-24","url":null,"abstract":"","PeriodicalId":74086,"journal":{"name":"Longhua Chinese medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41733044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mostafa A Elfawal, Olivia Gray, Claire Dickson-Burke, Pamela J Weathers, Stephen M Rich
{"title":"<i>Artemisia</i> annua and artemisinins are ineffective against human <i>Babesia microti</i> and six <i>Candida</i> sp.","authors":"Mostafa A Elfawal, Olivia Gray, Claire Dickson-Burke, Pamela J Weathers, Stephen M Rich","doi":"10.21037/lcm-21-2","DOIUrl":"10.21037/lcm-21-2","url":null,"abstract":"<p><strong>Background: </strong><i>Artemisia annua</i> L.is a well-established medicinal herb used for millennia to treat parasites and fever-related ailments caused by various microbes. Although effective against many infectious agents, the plant is not a miracle cure and there are infections where it has proved ineffective or limited. It is important to report those failures.</p><p><strong>Methods: </strong>Here artemisinin, artesunate and dried leaf slurries of <i>A. annua</i> were used daily for 6 days <i>in vivo</i> against <i>Babesia microti</i> in mice 2 days post infection at 100 µg artemisinin/kg body weight. Parasitemia was measure before and 15 days days post treatment. Artemisinin and extracts of <i>A. annua</i> also were tested <i>in vitro</i> against six <i>Candida</i> sp. at artemisinin concentrations up to 180 µM and growth measured after cultures were fed drugs once at different stages of growth and also after repeated dosing.</p><p><strong>Results: </strong><i>A. annua</i>, artesunate, and artemisinin were ineffective in reducing or eliminating parasitemia in <i>B. microti</i>-infected mice treated at 100 µg artemisinin/kg body weight. Although the growth of exponential cultures of many of the tested <i>Candida</i> sp. was inhibited, the response was not sustained and both artemisinin and <i>Artemisia</i> were essentially ineffective at concentrations of artemisinin at up to 180 µM of artemisinin.</p><p><strong>Conclusions: </strong>Together these results show that artemisinin, its derivatives, and <i>A. annua</i> are ineffective against <i>B. microti</i> and at least six species of <i>Candida</i>.</p>","PeriodicalId":74086,"journal":{"name":"Longhua Chinese medicine","volume":"4 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/09/ff/nihms-1720579.PMC8312716.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39227616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Regulation of Chinese medicine in Poland","authors":"Marek Kalmus","doi":"10.21037/lcm-20-38","DOIUrl":"https://doi.org/10.21037/lcm-20-38","url":null,"abstract":": The Polish Jesuit missionary Michl Piotr Boym was the first European in the middle of 17th century, who studied Chinese medicine and brought that knowledge from China to Europe. Two first doctoral theses on Chinese medicine were defended in Poland in the 1930s. Medical acupuncture was introduced in 1978 and taught by Prof. Zbigniew Garnuszewski in Warsaw and officially recognized. The real traditional Chinese medicine (TCM) education started in 1986 in Krakow and after some years of private education the first TCM school was established. In Poland, education in TCM is not regulated until now and different TCM schools have their own curriculum, level and duration of education. There are six associations for acupunture and TCM in Poland. Two of them are really active. TCM and acupuncture are not regulated by Polish law, but they are not prohibited. Acupuncturists as well as herbalist-phytotherapists are officially recognized by the Ministry of Labour and Social Policy. TCM can be practiced clinically by anyone and is not controlled by any professional TCM authorities. The number of TCM clinics is growing all over Poland due to the weakness of the public health system. Many patients are seeking holistic and safe treatment free of negative side effects.","PeriodicalId":74086,"journal":{"name":"Longhua Chinese medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45953957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The traditional Chinese medicine WuJiaPi (Acanthopanacis cortex) and its main anti-inflammatory terpenoids","authors":"C. Bailly","doi":"10.21037/LCM-21-1","DOIUrl":"https://doi.org/10.21037/LCM-21-1","url":null,"abstract":": The root bark of the plant Acanthopanax gracilistylus is commonly used in traditional Chinese medicine for the treatment of rheumatism, arthritis and other inflammatory pathologies and conditions. The medication, referred to as Acanthopanacis cortex or WuJiaPi, is also used for a long time to strengthen bones (to reduce osteoporosis) and to protect the liver and kidneys. The antioxidant, anti-inflammatory and anti-proliferative properties of WuJiaPi extracts have been well-characterized and associated with the presence of various bioactive terpenoids (such as gracilistones, wujiapiosides) and phenylpropanoid glycosides (such as eleutherosides). Among them, the lupane triterpene acankoreagenin (also known as HLEDA) stands as a potent inhibitor of the NF- κ B signaling pathway, capable of blocking the secretion of the alarmin HMGB1 and reducing the expression of pro-inflammatory cytokines by activated or infected macrophages. Acankoreagenin displays marked anti-inflammatory and anti-oedema actions in vitro and in vivo , comparable to the activity of the analogue impressic acid. This brief review shed light on the biological properties of this pentacyclic sapogenin and its various glycoside derivatives. Among the 16 acankoreosides isolated from various Acanthopanax species, acankoreoside A emerges as one of the most potent regulators of NF- κ B and an efficient blocker of inflammatory cytokines production. Acankoreosides B and D also exhibit significant anti-inflammatory effects. Acankoreagenin, acankoreosides and a few other terpenoids contribute importantly to the efficacy of the WuJiaPi TCM.","PeriodicalId":74086,"journal":{"name":"Longhua Chinese medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46861724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}