Longhua Chinese medicine最新文献

{"title":"Pharmacological activity of saffron and crocin on dementia: a narrative review","authors":"Yui Sasaki, K. Kanazawa, Koichi Shimizu, Y. Shoyama","doi":"10.21037/lcm-22-7","DOIUrl":"https://doi.org/10.21037/lcm-22-7","url":null,"abstract":"","PeriodicalId":74086,"journal":{"name":"Longhua Chinese medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49632512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Decoding cancer and herbal renaissance.","authors":"Lan Ko","doi":"10.21037/lcm-22-12","DOIUrl":"https://doi.org/10.21037/lcm-22-12","url":null,"abstract":"<p><p>The original notion in quest of cancer targets to end cancer still stands, yet the secret of common human cancer was concealed by a chicken-egg paradox. Solid tumors initiate in the tumor microenvironment from rare stem cells, which express a mutant target protein as their specific marker. For decades, the stem cell and target protein cannot paradoxically be found one without first finding the other. With combined evidence from genetics, pathology, stem cell biology, clinical oncology, and herbal medicine in particular, this paradox is resolved. Historical successful anticancer herbs, together with clinical oncology drugs, paved the way to decode cancer. In solid tumors, the liable stem cells are pericyte stem cells on blood vessels in the tumor microenvironment inducing angiogenesis. One identified target protein in pericytes is a DNA repair factor and transcriptional regulator named GT198 (gene symbol <i>PSMC3IP</i>, alias name Hop2). Since GT198 is found as a direct drug target of many chemotherapy drugs and clinically successful anticancer herbs, more herbal medicines worldwide can now be screened against this target. In the near future, safer and more effective natural herbal medicines could systematically treat common solid tumors. This review discusses a unified theory of cancer and diseases in which pericyte stem cells are fundamental to both. It also reveals a new approach to identifying multi-functional herbs. Unlocking herbal targets in stem cells enables effective herbal identification and, in turn, awakens the herbal renaissance.</p>","PeriodicalId":74086,"journal":{"name":"Longhua Chinese medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c7/32/nihms-1829179.PMC9555574.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33510074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comparative study of high-pressure processing and microwave pasteurisation on the formation of hydroxymethylfurfural in stingless bee (Heterotrigona itama) honey","authors":"Syahrul Anis Hazwani Mohd Baroyi, Y. Yusof, N. Chin, S. H. Othman, Nashratul Shera Mohamad Ghazali","doi":"10.21037/lcm-22-13","DOIUrl":"https://doi.org/10.21037/lcm-22-13","url":null,"abstract":"","PeriodicalId":74086,"journal":{"name":"Longhua Chinese medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49038171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Glucose Ketone Index predicts overall survival and metastasis of mouse tumor cells to visceral organs and brain","authors":"Zeynep Akgoc, P. Mukherjee, T. Seyfried","doi":"10.21037/lcm-21-43","DOIUrl":"https://doi.org/10.21037/lcm-21-43","url":null,"abstract":"","PeriodicalId":74086,"journal":{"name":"Longhua Chinese medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43543511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of crocin on neuroprotective activity in vitro: a narrative review","authors":"S. Soeda, Tomoe Ohta, T. Uto, Y. Shoyama","doi":"10.21037/lcm-22-4","DOIUrl":"https://doi.org/10.21037/lcm-22-4","url":null,"abstract":"","PeriodicalId":74086,"journal":{"name":"Longhua Chinese medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43490506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cognitive functions of saffron and its major constituent crocin, a narrative review","authors":"M. Sugiura, K. Abe, H. Saito, Tomoe Ohta, T. Uto, Y. Shoyama","doi":"10.21037/lcm-22-5","DOIUrl":"https://doi.org/10.21037/lcm-22-5","url":null,"abstract":"","PeriodicalId":74086,"journal":{"name":"Longhua Chinese medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42923842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ear acupuncture and neuromodulation: narrative review","authors":"Marcos Lisboa Neves, Bernardo Diniz Coutinho, Emiliana Domingues Cunha da Silva, L. Gentil, A. R. S. dos Santos, M. D. da Silva","doi":"10.21037/lcm-21-42","DOIUrl":"https://doi.org/10.21037/lcm-21-42","url":null,"abstract":"","PeriodicalId":74086,"journal":{"name":"Longhua Chinese medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46591135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acupuncture for neck pain: current evidence and challenges","authors":"Sileyda Costa, A. S. Ferreira","doi":"10.21037/lcm-22-8","DOIUrl":"https://doi.org/10.21037/lcm-22-8","url":null,"abstract":"","PeriodicalId":74086,"journal":{"name":"Longhua Chinese medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46004038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A narrative review on the main chemical constituents and bioactivity of Camellia nitidissima Chi","authors":"Hanyu Zheng, Q. Du, J. Yin, Ying Gao","doi":"10.21037/lcm-22-9","DOIUrl":"https://doi.org/10.21037/lcm-22-9","url":null,"abstract":"Camellia nitidissima Chi have boomed. Various components in Camellia nitidissima Chi have been identified and some of its health-beneficial functions have been demonstrated. The review aims to supply an overview of the main chemical components and health-beneficial functions of Camellia nitidissima Chi. Methods: The references in this review are mainly collected from published books and the scientific literature databases including Web of science, PubMed, and China National Knowledge Infrastructure, with a timeframe from January 1986 to March 2022, containing English and Chinese references. Key Content and Findings: Chemical analysis reveals that Camellia nitidissima Chi contains a variety of chemical constituents, including phenolic compounds, saponins, polysaccharides, and other substances. Phenolic compounds, particularly flavonoids, are the most well-studied components in Camellia nitidissima Chi. Many of them are bioactive and contribute to the health-beneficial functions of Camellia nitidissima Chi. Plenty of studies confirm that Camellia nitidissima Chi have effects on antioxidant, anti-cancer, anti-hyperglycemia, anti-hyperlipidemia, anti-allergy, and anti-depression. Part of the underlying mechanisms are unveiled. Conclusions: Based on current research progress, Camellia nitidissima Chi has the potential to be applied in dietary supplements and even medications. More studies are needed to further figure out its working mechanisms and assess its effectiveness in humans. leaves. The content and composition of free amino acids in C . nitidissima flowers are not quite the same as that in C . nitidissima leaves. Huang et al. (46) revealed that 17 types of amino acids were observed in C . nitidissima flowers. The content of free amino acids in C . nitidissima flowers ranged from was 4.32% to 5.46%, reaching the top at the fish-mouth stage. Essential amino acids accounted for 38% of total free amino acids in C . nitidissima flowers.","PeriodicalId":74086,"journal":{"name":"Longhua Chinese medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42150876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of saffron and its active constituent crocin on cancer management: A narrative review.","authors":"Chong-Zhi Wang,&nbsp;Qinge Ma,&nbsp;Sharon Kim,&nbsp;Daniel H Wang,&nbsp;Yukihiro Shoyama,&nbsp;Chun-Su Yuan","doi":"10.21037/lcm-21-72","DOIUrl":"https://doi.org/10.21037/lcm-21-72","url":null,"abstract":"<p><strong>Background and objective: </strong>Cancer is a major public health problem in the world, and it dramatically affects the life expectancy of patients and their quality of life. Natural products from botanicals could be beneficial in the prevention or treatment of a variety of cancers. Saffron (the extract of <i>Crocus sativus</i>) includes its major constituent, crocin, have been used as a folk medicine for a long time, and they have shown obvious cancer chemoprevention potential. The objectives of this review are to present the progress of research on the effects of saffron and crocin in cancer management and the underlying mechanisms of action.</p><p><strong>Methods: </strong>We searched publications in the English language, published between January 1, 1980 and September 30, 2022, of saffron and crocin on cancer through several search engines, i.e., PubMed, SciFinder and Web of Science.</p><p><strong>Key content and findings: </strong>In this article, we first summarize the phytochemical studies of this botanical. Then, we present the anticancer effects of saffron and crocin on different human cancer cells. Saffron and crocin showed obvious antiproliferative effects on human cancer cell lines, including colorectal cancer, breast cancer, lung cancer, prostate cancer, cervical cancer, leukemia, glioblastoma and rhabdomyosarcoma. Finally, the anticancer-related mechanisms of action are summarized, including cell cycle arrest at G0/G1 or G2/M phases, induction of caspase-dependent apoptosis, signaling pathway-linked tumor metabolism regulation, and adaptive immunity regulated inflammation of host immune responses.</p><p><strong>Conclusions: </strong>Previous studies related to saffron and crocin in cancer management have been reviewed and reported results have been analyzed. Clinical data suggest that saffron and crocin have beneficial effects to improve quality of life in cancer patients. Thus, saffron and crocin can be considered promising candidates for future clinical cancer studies.</p>","PeriodicalId":74086,"journal":{"name":"Longhua Chinese medicine","volume":"5 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10309162/pdf/nihms-1856047.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9799788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}