Korean journal of clinical oncology最新文献_第6页

Short-course radiotherapy and chemotherapy for conversion surgery in patients with unresectable metastatic rectal cancer: a preliminary case series study. 不可切除的转移性直肠癌转换手术患者的短期放疗和化疗:初步病例系列研究。

Korean journal of clinical oncology Pub Date : 2021-12-01 DOI: 10.14216/kjco.21017

Youngbae Jeon, Kyoung-Won Han, Seok Ho Lee, Sun Jin Sym, Seung Joon Choi, Seung Yeon Ha, Jeong-Heum Baek

{"title":"Short-course radiotherapy and chemotherapy for conversion surgery in patients with unresectable metastatic rectal cancer: a preliminary case series study.","authors":"Youngbae Jeon, Kyoung-Won Han, Seok Ho Lee, Sun Jin Sym, Seung Joon Choi, Seung Yeon Ha, Jeong-Heum Baek","doi":"10.14216/kjco.21017","DOIUrl":"https://doi.org/10.14216/kjco.21017","url":null,"abstract":"Purpose: Curative treatment is challenging in patients with locally advanced rectal cancer and unresectable metastases. The aim of this study was to evaluate the clinical outcomes of short-course radiotherapy (RT) followed by systemic chemotherapy for patients with rectal cancer with mesorectal fascia (MRF) involvement and unresectable distant metastases.Methods: The study included consecutive patients diagnosed as having metastatic mid-to-low rectal cancer treated with short-course RT followed by systemic chemotherapy for conversion radical or palliative surgery between 2014 and 2019 at Gil Medical Center. The patients had primary rectal tumors involving the MRF and unresectable distant metastases. The treatment strategies were determined in a multidisciplinary team discussion.Results: Seven patients (five men and two women) underwent short-course RT (5×5 Gy) and preoperative systemic chemotherapy. The median age was 68 years (range, 46-84 years), and the median distance from the anal verge to the primary tumor was 6.0 cm (range, 2.0-9.0 cm). During the median follow-up period of 29.4 months, three patients underwent conversion radical surgery with R0 resection, two underwent palliative surgery, and two could not undergo surgery. No postoperative major morbidity or mortality occurred. The patients who underwent conversion complete radical surgery showed good long-term survival outcomes, with an overall survival time of 29.4-48.8 months and progression-free survival time of 14.7-41.1 months.Conclusion: Short-course RT followed by systemic chemotherapy could provide patients with unresectable stage IV rectal cancer a chance to undergo to conversion radical surgery with good long-term survival outcomes.","PeriodicalId":74045,"journal":{"name":"Korean journal of clinical oncology","volume":"17 2","pages":"111-116"},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9b/9c/kjco-17-2-111.PMC9942748.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9529540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prognostic significance of splenectomy during completion total gastrectomy in patients with remnant gastric cancer: propensity score matching analysis. 残余胃癌完全全胃切除术中脾切除术的预后意义:倾向评分匹配分析。

Korean journal of clinical oncology Pub Date : 2021-12-01 DOI: 10.14216/kjco.21015

Seung Hyun Back, Sung Eun Oh, Ji Yeong An, Min-Gew Choi, Tae Sung Sohn, Jae Moon Bae, Jun Ho Lee

{"title":"Prognostic significance of splenectomy during completion total gastrectomy in patients with remnant gastric cancer: propensity score matching analysis.","authors":"Seung Hyun Back, Sung Eun Oh, Ji Yeong An, Min-Gew Choi, Tae Sung Sohn, Jae Moon Bae, Jun Ho Lee","doi":"10.14216/kjco.21015","DOIUrl":"https://doi.org/10.14216/kjco.21015","url":null,"abstract":"Purpose: Splenectomy for patients with remnant gastric cancer has been controversial. The purpose of this study is to identify the impact of splenectomy in the treatment of remnant gastric cancer.Methods: We retrospectively analyzed 285 patients with remnant gastric cancer who underwent completion total gastrectomy with or without splenectomy in Samsung Medical Center, between September 1996 and December 2017. We used a 1:1 propensity score matching method for the analysis. The matching factors were age, sex, and pathologic stage. After the matching process, we compared the 5-year overall survival (OS) and the disease-free survival (DFS) between patients with and without splenectomy during completion total gastrectomy.Results: The median duration of follow-up was 58.0 months (range, 0-132 months). After propensity score matching, there were no statistically significant differences between the splenectomy group (n=77) and no splenectomy group (n=77) in terms of clinicopathological features. The 5-year OS rate between the no splenectomy and splenectomy group were not significantly different. There was no significant difference between 5-year DFS of the matched groups. Multivariate analysis revealed that splenectomy is not a significant prognostic factor in terms of 5-year OS (no splenectomy vs. splenectomy; 61.5% vs. 60.2%, P=0.884) or DFS (74.9% vs. 69.8%, P=0.880).Conclusion: Splenectomy has no impact on the OS and DFS in patients with remnant gastric cancer. Splenectomy during completion total gastrectomy may not be necessary.","PeriodicalId":74045,"journal":{"name":"Korean journal of clinical oncology","volume":"17 2","pages":"96-103"},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/83/18/kjco-17-2-96.PMC9942751.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9529541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rare case of postoperative mediastinitis following thyroidectomy. 甲状腺切除术后纵隔炎罕见病例。

Korean journal of clinical oncology Pub Date : 2021-06-01 DOI: 10.14216/kjco.21009

In Soo Cho, Moo Hyun Lee, Jihyoung Cho

{"title":"Rare case of postoperative mediastinitis following thyroidectomy.","authors":"In Soo Cho, Moo Hyun Lee, Jihyoung Cho","doi":"10.14216/kjco.21009","DOIUrl":"https://doi.org/10.14216/kjco.21009","url":null,"abstract":"Descending necrotizing mediastinitis (DNM) is a life-threatening complication secondary to oropharyngeal abscesses, cervical esophageal perforation, or neck infections spreading along the fascial planes into the mediastinum. Post-thyroidectomy surgical site infection is a highly unusual complication that is typically localized around the incision, but may be propagated into the mediastinum, causing DNM. We encountered a case of this rare complication after thyroidectomy. The patient was a 33-year-old woman who was admitted to our center for left hemithyroidectomy. The surgery was performed without any intraoperative events. However, she later developed fever, hypotension, and tachycardia. Imaging revealed deep neck emphysema and focal pneumomediastinum with infiltration in the anterior neck and mediastinum with abscess formation. Additional imaging at 7 days postoperatively revealed reduced fluid collection deep in the neck with minimal changes in fluid collection in the mediastinum. Esophageal perforation was excluded via an esophagogram, which lead to the conclusion that the infection may have been caused by open thyroidectomy. The patient was treated with prompt medical and surgical intervention. After treatment, she was discharged from the hospital with no further complications. We present our case report as well as a literature review of the diagnosis and treatment of this disease.","PeriodicalId":74045,"journal":{"name":"Korean journal of clinical oncology","volume":"17 1","pages":"52-55"},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/64/62/kjco-17-1-52.PMC9942740.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9215081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A comparative study of the clinical characteristics and outcomes of HR-positive HER2-negative breast cancer patients over and under 65 years old. 65岁以上和65岁以下hr2阳性乳腺癌患者临床特征及转归的比较研究

Korean journal of clinical oncology Pub Date : 2021-06-01 DOI: 10.14216/kjco.21001

Chang Shin Jung, Youn Joo Jung, Dong Il Kim, Seungju Lee, Seok Kyung Kang, Su Bong Nam, Hyun Yul Kim

{"title":"A comparative study of the clinical characteristics and outcomes of HR-positive HER2-negative breast cancer patients over and under 65 years old.","authors":"Chang Shin Jung, Youn Joo Jung, Dong Il Kim, Seungju Lee, Seok Kyung Kang, Su Bong Nam, Hyun Yul Kim","doi":"10.14216/kjco.21001","DOIUrl":"https://doi.org/10.14216/kjco.21001","url":null,"abstract":"Purpose: The purpose of this study was to compare the clinical characteristics and outcomes of hormone receptor-positive (HR+) human epidermal growth factor 2-negative (HER2-) breast cancer among elderly patients (over 65 years old) and younger patients.Methods: This was a retrospective cohort study of 328 patients who were treated for breast cancer at Pusan National University Yangsan Hospital between January 2009 and December 2014. Tumor characteristics, surgical methods, and survival outcomes were compared between the two age groups (<65 and ≥65 years old). Kaplan-Meier curves for disease-free survival (DFS) and overall survival (OS) were also constructed according to the age groups.Results: Among the 328 patients with HR+ HER2- breast cancer, 184 (56.1%) were <65 years old and 144 (43.9%) were ≥65 years old. Breast cancer stages were similar between the two age groups, but the older patients were treated less often with chemotherapy (81% vs. 66%, P=0.002). During the follow-up period, 17 deaths and 36 cases of recurrence or metastasis were reported. There was no difference in DFS between the two groups (P=0.840); however, the OS of the older age group was significantly lower than that of the younger age group (P=0.015).Conclusion: This study suggested that HR+ HER2- breast cancer patients belonging to the two age groups had no significant difference in DFS. However, older age is an independent factor affecting OS rate. Therefore, even if patients are old, but their physical condition is satisfactory, standard and active treatment may be necessary, similar to that given to younger patients.","PeriodicalId":74045,"journal":{"name":"Korean journal of clinical oncology","volume":"17 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2e/90/kjco-17-1-1.PMC9942741.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9513448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adjuvant chemotherapy for patients with stage II high-risk and III colon cancer: Hindering factors to adherence and impact on long-term survival. II期和III期高危结肠癌患者的辅助化疗:阻碍依从性的因素及对长期生存的影响

Korean journal of clinical oncology Pub Date : 2021-06-01 DOI: 10.14216/kjco.21002

Jieun Kim, Ri Na Yoo, Hyeon-Min Cho, Bong-Hyeon Kye, Hyung Jin Kim

{"title":"Adjuvant chemotherapy for patients with stage II high-risk and III colon cancer: Hindering factors to adherence and impact on long-term survival.","authors":"Jieun Kim, Ri Na Yoo, Hyeon-Min Cho, Bong-Hyeon Kye, Hyung Jin Kim","doi":"10.14216/kjco.21002","DOIUrl":"https://doi.org/10.14216/kjco.21002","url":null,"abstract":"Purpose: Adjuvant chemotherapy is recommended after curative surgery in patients with colon cancer of high-risk stage II and stage III. However, a considerable number of patients cannot complete the scheduled adjuvant treatment for various reasons. This study investigates the hindering factors to the adherence to adjuvant chemotherapy and their impact on long-term survival.Methods: A retrospective study was conducted for patients with colon cancer and had curative resection from 2009 to 2014. Among patients with pathologic stage II and III, stage II with low-risk features, double primary cancers, R2 resection cases were excluded. Patients were grouped into three groups: no-adjuvant therapy, adjuvant therapy for less than 3 months, and more than 3 months. Factors for withdrawal and the oncologic outcome were analyzed.Results: Of 571 patients, adjuvant chemotherapy was recommended in 403. One hundred and sixteen patients (28.8%) did not receive adjuvant chemotherapy, 78 (19.4%) withdrew within 3 months, and 209 (51.9%) maintained for more than 3 months. Factors for not receiving adjuvant chemotherapy or withdrawing within 3 months were older than 70 and American Society of Anesthesiologists class 3 or higher. Main reasons for discontinuation before 3 months were chemotoxicity and patient's refusal. The long-term oncologic outcome of the patients who received adjuvant chemotherapy for more than 3 months was significantly better than others.Conclusion: No-adjuvant therapy or receiving them for lesser than 3 months is significantly affected by the patient's performance status and social support, which coincides with a poor oncologic outcome. Social support and rehabilitation system may help to improve the survival outcome.","PeriodicalId":74045,"journal":{"name":"Korean journal of clinical oncology","volume":"17 1","pages":"8-14"},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a9/89/kjco-17-1-8.PMC9942742.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9513449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Erratum to: The current status of cancer survivorship care and a consideration of appropriate care model in Korea. 韩国癌症生存护理的现状和适当护理模式的考虑。

Korean journal of clinical oncology Pub Date : 2021-06-01 DOI: 10.14216/kjco.20024.e1

Hye Mi Ko, Je-Ryong Kim, Jin Sun Lee

引用次数: 0

Tumor grade 2 as the independent predictor for lymph node metastasis in 10-20 mm sized rectal neuroendocrine tumor. 肿瘤分级2作为10- 20mm大小的直肠神经内分泌肿瘤淋巴结转移的独立预测因子。

Korean journal of clinical oncology Pub Date : 2021-06-01 DOI: 10.14216/kjco.21006

Byung-Soo Park, Sung Hwan Cho, Gyung Mo Son, Hyun Sung Kim, Su Jin Kim, Su Bum Park, Cheol Woong Choi, Hyung Wook Kim, Dong Hoon Shin

{"title":"Tumor grade 2 as the independent predictor for lymph node metastasis in 10-20 mm sized rectal neuroendocrine tumor.","authors":"Byung-Soo Park, Sung Hwan Cho, Gyung Mo Son, Hyun Sung Kim, Su Jin Kim, Su Bum Park, Cheol Woong Choi, Hyung Wook Kim, Dong Hoon Shin","doi":"10.14216/kjco.21006","DOIUrl":"https://doi.org/10.14216/kjco.21006","url":null,"abstract":"Purpose: Rectal neuroendocrine tumors (NETs) <10 mm are endoscopically resected, while those ≥20 mm are treated with radical surgical resection. The choice of treatment for 10-20 mm sized rectal NETs remains controversial. This study aimed to verify factors predicting lymph node metastasis (LNM) of 10-20 mm sized rectal NET and utilize them to decide upon the treatment strategy.Methods: Twenty-eight patients with 10-20 mm sized rectal NETs treated at Pusan National University Yangsan Hospital from January 2009 to September 2020 were divided into LNM (+) and LNM (-) groups, and their respective data were analyzed.Results: Seven patients (25%) had LNM while 21 patients (75%) did not. Endorectal ultrasound findings showed tumor size was significantly larger in the LNM (+) than in the LNM (-) group (15 mm vs. 10 mm, P=0.018); however, pathologically, there was no significant difference in tumor size (13 mm vs. 11 mm, P=0.109). The mitotic count (P=0.011), Ki-67 index (P=0.008), and proportion of tumor grade 2 patients (5 cases, 71% vs. 1 case, 5%; P=0.001) were significantly higher in the LNM (+) group. In multivariate analysis, tumor grade 2 was the independent factor predicting LNM (odds ratio, 61.32; 95% confidence interval, 3.17-1,188.64; P=0.010).Conclusion: Tumor grade 2 was the independent factor predicting LNM in 10-20 mm sized rectal NETs. Therefore, it could be considered as the meaningful factor in determining whether radical resection is necessary.","PeriodicalId":74045,"journal":{"name":"Korean journal of clinical oncology","volume":"17 1","pages":"37-43"},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d9/d9/kjco-17-1-37.PMC9942737.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9215082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Erratum to: Radiologic intervention due to delayed gastric emptying after pylorus preserving gastrectomy for gastric cancer does not affect pyloric function. 更正:胃癌保幽门胃切除术后胃排空延迟的放射学干预不影响幽门功能。

Korean journal of clinical oncology Pub Date : 2021-06-01 DOI: 10.14216/kjco.20014.e1

Hyun Tae Lim, Shin-Hoo Park, Jong-Ho Choi, Jae Seok Bae, Seong-Ho Kong, Do Joong Park, Hyuk-Joon Lee, Se Hyung Kim, Han-Kwang Yang

引用次数: 0

Korean journal of clinical oncology Pub Date : 2021-06-01 DOI: 10.14216/kjco.21005

Geon Yi Jin, Ki Bum Park, Kyo Young Song

{"title":"Factors related to compliance with adjuvant chemotherapy in patients with gastric cancer: A retrospective single-center study.","authors":"Geon Yi Jin, Ki Bum Park, Kyo Young Song","doi":"10.14216/kjco.21005","DOIUrl":"https://doi.org/10.14216/kjco.21005","url":null,"abstract":"Purpose: Adjuvant chemotherapy (AC) improves survival outcomes in patients with advanced gastric cancer (GC) after curative surgery; however, some patients do not receive or complete chemotherapy. This study aimed to identify factors related to patient compliance with chemotherapy after curative surgery for advanced GC.Methods: The data of patients who underwent curative gastrectomy for pathologic stage II-III GC between 2012 and 2016 were reviewed. Patients were divided into an AC completion group (group C), AC incompletion group (group I), and surgery-only group (group S). The AC regimen was either tegafur/gimeracil/oteracil (S-1) or capecitabine plus oxaliplatin (XELOX).Results: The study enrolled 417 patients; group C had 222 patients, group I had 110, and group S had 85. The most common reason for not initiating AC was poor general condition (36.5%), while chemotherapy-related complications was the common reason for AC incompletion (43.6%). In multivariate analysis, age over 65 years, Eastern Cooperative Oncology Group performance status ≥1, Charlson comorbidity index ≥1, and the presence of postoperative complications were independent risk factors for not initiating AC (odds ratio: 4.32, 2.62, 1.84, and 2.17, respectively). Age over 65 years, longer postoperative stay, and XELOX regimen were significant risk factors for incompletion of AC (odds ratio: 2.68, 1.72, and 2.23, respectively).Conclusion: Old age, poor performance status, comorbidities, and postoperative complications, longer postoperative hospital stay, and XELOX regimen were associated with poor compliance with AC in GC patients. Clinicians can improve compliance with AC by managing postoperative complications and selecting the most appropriate treatment regimen.","PeriodicalId":74045,"journal":{"name":"Korean journal of clinical oncology","volume":"17 1","pages":"31-36"},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/5c/4f/kjco-17-1-31.PMC9942746.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9215083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Cecal malakoplakia: A case report. 盲肠斑疹1例。

Korean journal of clinical oncology Pub Date : 2021-06-01 DOI: 10.14216/kjco.21007

Jin Woon Jeong, Ji Hyun Noh, Jeong Hyun Kang, Ji Hyun Park, Joo Hyung Lee

{"title":"Cecal malakoplakia: A case report.","authors":"Jin Woon Jeong, Ji Hyun Noh, Jeong Hyun Kang, Ji Hyun Park, Joo Hyung Lee","doi":"10.14216/kjco.21007","DOIUrl":"https://doi.org/10.14216/kjco.21007","url":null,"abstract":"Malakoplakia is a rare chronic granulomatous disease found in the genitourinary tract, mainly. It is considered to be related to immunosuppression and/or infectious processes. We would like to present an operative case of cecal malakoplakia in a patient with a history of surgical resection and chemotherapy for cervical cancer. A 74-year-old female patient visited our hospital for 1-year follow-up after operation and chemo-radiotherapy for cervical cancer. An infiltrative mass of 6 cm, between the cecal base and the right psoas muscle, was observed on computed tomography. An ileocectomy was performed for diagnosis. Histopathologic examination revealed cecal malakoplakia. After surgery, based on previous reports, antibiotics therapy was added. Then the patient was discharged and treated in the outpatient clinic. To our knowledge, a rare case has been described of cecal malakoplakia during observation after surgery and chemo-radiotherapy for cervical cancer. Malakoplakia is known to be related to immunosuppressive condition. Therefore, our case suggests that close observation should be made in patients on immunosuppressive condition, such as chemotherapy.","PeriodicalId":74045,"journal":{"name":"Korean journal of clinical oncology","volume":"17 1","pages":"44-47"},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/18/d1/kjco-17-1-44.PMC9942739.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9513450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0