JTCVS open最新文献

{"title":"Commentary: Carpe diem! Moderate tricuspid regurgitation can no longer be ignored","authors":"Matthew Kazaleh DO, MSc, Ricky Patil MD, Gorav Ailawadi MD, MBA","doi":"10.1016/j.xjon.2025.04.015","DOIUrl":"10.1016/j.xjon.2025.04.015","url":null,"abstract":"","PeriodicalId":74032,"journal":{"name":"JTCVS open","volume":"25 ","pages":"Pages 85-86"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144321426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Segmentectomy versus lobectomy for centrally located small-sized and radiologically pure-solid non–small cell lung cancer","authors":"Norifumi Tsubokawa MD, PhD ,&nbsp;Takahiro Mimae MD, PhD ,&nbsp;Yoshihiro Miyata MD, PhD ,&nbsp;Chiaki Kanno MD ,&nbsp;Yujin Kudo MD, PhD ,&nbsp;Takuya Nagashima MD, PhD ,&nbsp;Hiroyuki Ito MD, PhD ,&nbsp;Norihiko Ikeda MD, PhD ,&nbsp;Morihito Okada MD, PhD","doi":"10.1016/j.xjon.2025.03.028","DOIUrl":"10.1016/j.xjon.2025.03.028","url":null,"abstract":"<div><h3>Objectives</h3><div>This study aimed to compare segmentectomy and lobectomy in centrally located, small-sized (≤2 cm), radiologically pure-solid cN0 non–small cell lung cancer, particularly focusing on hypermetabolic tumors, because the feasibility of segmentectomy for centrally located, more aggressive non–small cell lung cancer remains uncertain.</div></div><div><h3>Methods</h3><div>We retrospectively evaluated 214 patients with centrally located small-sized (≤2 cm) and radiologically pure-solid cN0 non–small cell lung cancer who underwent segmentectomy (n = 82) or lobectomy (n = 132) at 3 institutions. Tumors located in the inner two-thirds of the pulmonary parenchyma were defined as centrally located. Propensity score matching was used to balance the baseline characteristics. Hypermetabolic tumors were identified based on the maximum standard uptake value, with high-grade malignancy indicated by the presence of pleural or lymphovascular invasion, or lymph node metastasis, as predicted by receiver operating characteristic curve.</div></div><div><h3>Results</h3><div>High-grade malignancy was confirmed in 115 patients (53.7%). After propensity score matching, no significant differences in clinical baseline characteristics were found among the 66 matched patients. Overall survival and recurrence-free survival did not significantly differ between segmentectomy and lobectomy groups (<em>P</em> = .253 and <em>P</em> = .463, respectively). Propensity score–adjusted multivariable Cox analysis revealed that segmentectomy was not an independent prognostic factor for overall survival or recurrence-free survival (<em>P</em> = .630 and <em>P</em> = .966, respectively). Regarding hypermetabolic tumors (maximum standard uptake value ≥2.65), overall survival and recurrence-free survival did not differ significantly between segmentectomy (n = 35) and lobectomy (n = 95) (<em>P</em> = .874 and <em>P</em> = .476, respectively).</div></div><div><h3>Conclusions</h3><div>Segmentectomy may be a feasible alternative to lobectomy in patients with centrally located, small-sized, and radiologically pure-solid non–small cell lung cancer, even in those with high-grade malignancy.</div></div>","PeriodicalId":74032,"journal":{"name":"JTCVS open","volume":"25 ","pages":"Pages 415-423"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144320931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does grade matter? Evaluation of histologic grade in patients with stage 1 non–small cell lung cancer using the National Cancer Database","authors":"Toyokazu Endo MD,&nbsp;Joshua Crane MD,&nbsp;Jaimin Trivedi MD, MPH,&nbsp;Matthew Black MD,&nbsp;Matthew Fox MD,&nbsp;Victor van Berkel MD, PhD","doi":"10.1016/j.xjon.2025.02.017","DOIUrl":"10.1016/j.xjon.2025.02.017","url":null,"abstract":"<div><h3>Background</h3><div>In the United States, histologic grade in non–small cell lung cancer (NSCLC) is not part of the TNM stage classification. We hypothesize that histologic grade may impact prognosis.</div></div><div><h3>Methods</h3><div>The National Cancer Database (NCDB) for NSCLC was used to identify all pathological stage 1 cancer patients who underwent definitive surgery between 2013 and 2020. Three groups were created using histologic grade for both adenocarcinoma and squamous cell carcinoma: well-differentiated (G1), moderately differentiated (G2), and poorly/undifferentiated (G3).</div></div><div><h3>Results</h3><div>The study cohort comprised 37,727 adenocarcinoma patients (10,784 G1, 18,647 G2, 8476 G3) and 17,697 squamous cell carcinoma patients (601 G1, 10,002 G2, 7904 G3) patients who underwent definitive surgical resection for stage 1 cancer. More patients in the G3 adenocarcinoma group had a larger tumor size (18 mm vs 20 mm vs 21 mm; <em>P</em> &lt; .001). Overall survival was significantly better for the G1 group (log-rank <em>P</em> &lt; .001) (G2 vs G1: HR, 1.51, <em>P</em> &lt; .001; G3 vs G1: HR, 1.9, <em>P</em> &lt; .001; G3 vs G2: HR, 1.26; <em>P</em> &lt; .001). In the squamous cell carcinoma patients, characteristics were comparable across the 3 groups. Similar to the adenocarcinoma patients, tumor size was larger in the squamous cell carcinoma G3 group (20 mm vs 22 mm vs 24 mm; <em>P</em> &lt; .001). Overall survival was not significantly different across the 3 squamous cell carcinoma groups (<em>P</em> &lt; .001).</div></div><div><h3>Conclusions</h3><div>Histologic grade for adenocarcinoma has gained international attention with the new classification scheme according to the International Association for Study of Lung Cancer. Histologic grade, at least in adenocarcinoma, may provide an important prognostic indicator, and further work is needed to tailor treatment for those with high-grade tumors.</div></div>","PeriodicalId":74032,"journal":{"name":"JTCVS open","volume":"25 ","pages":"Pages 393-405"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144320937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute kidney injury after heart valve surgery: Incidence and impact on mortality based on serum creatinine and urine output criteria","authors":"Ho Jin Kim MD, PhD ,&nbsp;Jin Kyoung Kim MD ,&nbsp;Seon-Ok Kim MSc ,&nbsp;Yeji Han MD ,&nbsp;Pilje Kang MD ,&nbsp;Joon Bum Kim MD, PhD","doi":"10.1016/j.xjon.2025.03.027","DOIUrl":"10.1016/j.xjon.2025.03.027","url":null,"abstract":"<div><h3>Background</h3><div>The reported incidence of postoperative acute kidney injury (AKI) after cardiac surgery varies depending on the definition used. This study assessed the incidence and predictors of AKI and examined its association with clinical outcomes in patients undergoing heart valve surgery with the use of cardiopulmonary bypass (CPB).</div></div><div><h3>Methods</h3><div>We analyzed 4044 consecutive patients (mean age 60.1 ± 13.3 years; 1862 females) who underwent heart valve surgery between 2013 and 2021. Patients on hemodialysis or mechanical circulatory support and patients undergoing circulatory arrest were excluded. AKI was defined according to the Kidney Disease: Improving Global Outcomes (KDIGO) criteria. Logistic regression analysis was performed to identify predictors of AKI and estimate its probability.</div></div><div><h3>Results</h3><div>AKI occurred in 1261 patients (31.2%), with KDIGO stage 1 the most prevalent (n = 791; 19.6%). Operative mortality was proportionately higher in patients with more severe stages of AKI (2.6% in stage 2% and 17.7% in stage 3). A total of 502 patients died during a median follow-up of 5.7 years. AKI stage 2 (hazard ratio, 2.01; <em>P</em> &lt; .001) and stage 3 (hazard ratio, 4.31; <em>P</em> &lt; .001) were significantly associated with an increased risk of mortality. Decreased renal function and prolonged CPB time were independent predictors of severe AKI (stage 2 or 3). The estimated risk of severe AKI due to CPB use showed distinct patterns stratified by preoperative renal function.</div></div><div><h3>Conclusions</h3><div>AKI occurs in 31.2% of patients after heart valve surgery, as defined by the KDIGO criteria. Severe AKI is associated with increased overall mortality. Prolonged CPB time is related to severe AKI, particularly in patients with preoperative renal dysfunction.</div></div>","PeriodicalId":74032,"journal":{"name":"JTCVS open","volume":"25 ","pages":"Pages 294-307"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144321428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sex differences persist across surgical treatments in early-stage non–small cell lung cancer","authors":"Jessica Copeland MD, MPH ,&nbsp;Tayyiaba Farooq MS ,&nbsp;Sophia Phillips MS ,&nbsp;Taelyr Blehm BA ,&nbsp;Grace Drew BSA ,&nbsp;Endel Orav PhD","doi":"10.1016/j.xjon.2025.03.022","DOIUrl":"10.1016/j.xjon.2025.03.022","url":null,"abstract":"<div><h3>Objective</h3><div>Sex-based overall survival in patients with early-stage non–small cell lung cancer who undergo surgery is not well characterized. Existing data are limited by small sample sizes and underrepresentation of female patients or do not address overall survival according to surgical approach. The objective of this study was to compare overall survival among female and male patients with early-stage non–small cell lung cancer who underwent surgery.</div></div><div><h3>Methods</h3><div>Data were extracted from the National Cancer Database for all patients diagnosed with clinical stage I-IIB non–small cell lung cancer who underwent surgical resection from 2009 to 2018, had R₀ margins, and had at least 10 lymph nodes sampled for metastasis. Overall survival of the study sample was evaluated based on sex using multivariable Cox proportional hazards modeling and propensity score–matched analysis.</div></div><div><h3>Results</h3><div>Of the 79,209 patients included in the study sample, 43,218 (54.6%) were female. A propensity score–matched analysis of 23,988 female and 23,988 male patients with early-stage non–small cell lung cancer who underwent surgery showed that the female group had significantly improved 5-year overall survival at 71.2% (95% CI, 70.5-71.8) compared with the male group at 61.7% (95% CI, 61.0-62.4) (log-rank, <em>P</em> &lt; .0001).</div></div><div><h3>Conclusions</h3><div>Female patients with early-stage non–small cell lung cancer who underwent surgery had significantly better overall survival at 5 years when compared with their male counterparts.</div></div>","PeriodicalId":74032,"journal":{"name":"JTCVS open","volume":"25 ","pages":"Pages 406-414"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144321343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The prevalence and predictors of post–intensive care syndrome following cardiac surgery","authors":"Amanda Rea DNP, CRNP ,&nbsp;Sarah Holler MSN, RN ,&nbsp;Rakesh Arora MD ,&nbsp;Rebecca Hottle DNP, CRNP ,&nbsp;Clifford Fonner BA ,&nbsp;Olivia Marx ,&nbsp;Rawn Salenger MD","doi":"10.1016/j.xjon.2025.03.017","DOIUrl":"10.1016/j.xjon.2025.03.017","url":null,"abstract":"<div><h3>Objective</h3><div>Post–intensive care syndrome has been well documented in the general critical care population, but the prevalence of post–intensive care syndrome in the cardiac surgery population remains uncertain. We sought to define the prevalence of post–intensive care syndrome and associated risk factors after adult cardiac surgery.</div></div><div><h3>Methods</h3><div>Data were collected on 397 consecutive adult patients undergoing cardiac surgery. The patients were surveyed 4 weeks after surgery using the Healthy Aging Brain Care Monitor Self-Report version between June 2022 and June 2023.</div></div><div><h3>Results</h3><div>Seventy percent of patients reported symptoms consistent with mild (50%) or severe (20%) post–intensive care syndrome. Patients with severe post–intensive care syndrome score were more likely to be female (<em>P =</em> .04), to be White (<em>P =</em> .03), and to have new dialysis (<em>P =</em> .01). Hypoglycemia (<em>P &lt;</em> .001) and high Richmond Agitation Sedation Scale score (<em>P =</em> .001) were also associated with severe post–intensive care syndrome. Further, a history of diabetes (<em>P =</em> .05), depression (<em>P =</em> .01), and anxiety (<em>P =</em> .01) were more commonly observed in patients with post–intensive care syndrome.</div></div><div><h3>Conclusions</h3><div>Our study demonstrated a significant prevalence of post–intensive care syndrome after cardiac surgery. We identified female gender, White race, hemodialysis, hypoglycemia, and higher Richmond Agitation Sedation Scale scores as factors associated with increased risk of post–intensive care syndrome.</div></div>","PeriodicalId":74032,"journal":{"name":"JTCVS open","volume":"25 ","pages":"Pages 275-279"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144321485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of socioeconomic status on postoperative outcomes in acute type A aortic dissection repair","authors":"Benjamin Hambright BS ,&nbsp;Lamario Williams MD, PhD ,&nbsp;Rongbing Xie DrPH, MPH ,&nbsp;Sasha A. Still MD","doi":"10.1016/j.xjon.2025.01.013","DOIUrl":"10.1016/j.xjon.2025.01.013","url":null,"abstract":"<div><h3>Objective</h3><div>Type A aortic dissection repair is an emergency operation associated with both higher perioperative and postoperative risk. This study investigates the influence of socioeconomic status, as measured by the Distressed Communities Index (DCI), on patients who underwent acute aortic dissection repair and their postoperative outcomes.</div></div><div><h3>Methods</h3><div>We conducted a retrospective analysis of 240 adult patients who underwent repair for acute Stanford Type A aortic dissection from 2009 to 2021. Patients were categorized into an at-risk group (DCI score ≥75) and a not-at-risk group (DCI score &lt;75) based on their zip code. We collected demographic, clinical, operative, and postoperative outcomes, analyzing data using descriptive statistics and multivariable logistic regression. Kaplan-Meier survival analysis assessed 5-year survival outcomes.</div></div><div><h3>Results</h3><div>At-risk patients were significantly younger (52 vs 59 years; <em>P</em> = .03) and more commonly African American (59.02% vs 26.5%; <em>P</em> &lt; .0001). Although chronic health condition rates were similar, at-risk patients showed trends toward higher rates of postoperative respiratory failure (27.1% vs 18.0%; <em>P</em> = .0926) and longer hospital stays (27.05% vs 15.25% for length of stay of 8-13 days; <em>P</em> = .065). However, rates of postoperative complications, including 30-day mortality and 5-year survival, were not significantly different between groups, and at-risk status did not significantly predict mortality (hazard ratio, 1.35; 95% CI, 0.65-2.79; <em>P</em> = .43).</div></div><div><h3>Conclusions</h3><div>Patients undergoing urgent surgery for acute Type A aortic dissection have similar postoperative outcomes, although at-risk patients may experience longer hospital stays and higher respiratory failure rates. Further study is necessary to understand the effect of DCI score on intermediate and long-term outcomes to mitigate social disparities and diminish modifiable risk factors.</div></div>","PeriodicalId":74032,"journal":{"name":"JTCVS open","volume":"24 ","pages":"Pages 332-340"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143854587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Presentation, management, and clinical outcomes of acute type A dissection: Does sex matter?","authors":"Frederike Meccanici BSc ,&nbsp;Carlijn G.E. Thijssen MD, PhD ,&nbsp;Arjen L. Gökalp MD ,&nbsp;Marie H.E.J. van Wijngaarden MD ,&nbsp;Mark F.A. Bierhuizen MD ,&nbsp;Guy F. Custers MD ,&nbsp;Jort Evers BSc ,&nbsp;Jolien A. de Veld MD ,&nbsp;Maximiliaan L. Notenboom BSc ,&nbsp;Guillaume S.C. Geuzebroek MD, PhD ,&nbsp;Joost F.J. ter Woorst MD, PhD ,&nbsp;Jelena Sjatskig MD ,&nbsp;Robin H. Heijmen MD, PhD ,&nbsp;Mostafa M. Mokhles MD, PhD ,&nbsp;Roland R.J. van Kimmenade MD, PhD ,&nbsp;Jos A. Bekkers MD, PhD ,&nbsp;Johanna J.M. Takkenberg MD, PhD ,&nbsp;Jolien W. Roos-Hesselink MD, PhD","doi":"10.1016/j.xjon.2024.12.006","DOIUrl":"10.1016/j.xjon.2024.12.006","url":null,"abstract":"<div><h3>Background</h3><div>Male–female differences in clinical presentation, management, and outcomes of acute type A aortic dissection (AD-A) have been reported; however, robust data are scarce. This study examined those differences.</div></div><div><h3>Methods</h3><div>Consecutive adults diagnosed with AD-A between 2007 and 2017 in 4 referral centers were included retrospectively. Baseline data, operative characteristics, and mortality and morbidity during follow-up were collected using patient files, questionnaires, and referral information.</div></div><div><h3>Results</h3><div>The study included 889 patients (37.5% female). Females were significantly older at presentation (median, 67.0 [interquartile range [IQR], 59.0-75.0] years vs 61.0 [IQR, 53.0-69.0] years; <em>P</em> &lt; .001) and more often had cardiovascular comorbidities. Severe hypotension, tamponade, and nausea were more frequently observed in females. Short-term mortality was 18.5% in females and 21.2% in males (<em>P</em> = .362). No significant differences in treatment between males and females were observed. After surgery, the median follow-up was 6.2 years (IQR, 3.5-9.2 years). Overall 10-year survival was 50.1% (95% confidence interval [CI], 43.6%-57.6%) in females and 62.8% (95% CI, 58.1%-67.9%) in males (<em>P</em> = .009), although this difference was not significant after multivariable correction. Compared to the matched general population, survival was lower than expected in females and comparable to expected in males. The long-term reintervention rate in surgically treated survivors was comparable between males and females (2.1%/patient-year). Male- and female-specific risk factors for long term mortality were identified.</div></div><div><h3>Conclusions</h3><div>These findings highlight a distinct clinical profile at presentation with AD-A between males and females, while treatment approach and short-term mortality were comparable. The relatively poor long-term survival in females and male-/female-specific risk stratification warrant further investigation.</div></div>","PeriodicalId":74032,"journal":{"name":"JTCVS open","volume":"24 ","pages":"Pages 47-57"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143854866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Commentator Discussion: Impact of left ventricular rehabilitation on surgical outcomes in patients with borderline left heart hypoplasia","authors":"","doi":"10.1016/j.xjon.2024.10.020","DOIUrl":"10.1016/j.xjon.2024.10.020","url":null,"abstract":"","PeriodicalId":74032,"journal":{"name":"JTCVS open","volume":"24 ","pages":"Pages 374-375"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143854476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hospital readmission after heart valve surgery in the United Kingdom","authors":"Jeremy Chan MD,&nbsp;Pradeep Narayan MD,&nbsp;Tim Dong BSc,&nbsp;Daniel P. Fudulu MD, PhD,&nbsp;Gianni D. Angelini MD,&nbsp;CVD-COVID-UK/COVID-IMPACT Consortium","doi":"10.1016/j.xjon.2025.02.001","DOIUrl":"10.1016/j.xjon.2025.02.001","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate hospital readmission rates in the United Kingdom within the first 12 months following heart valve surgery.</div></div><div><h3>Methods</h3><div>All patients who underwent heart valve surgery between January 2013 and April 2023 were included in the study. Readmission to any National Health Service hospital within 12 months after discharge was captured. Trends in readmission, primary and secondary diagnoses, and related procedures were evaluated.</div></div><div><h3>Results</h3><div>A total of 44,467 patients (median age, 69.3 years; 61% male) were included, of whom 44.6%, 23.15%, and 11.95% experienced 1, 2, and 3 readmissions, respectively, within 12 months of discharge following the index procedure. The overall 30-day and 12-month readmission rates were 12.9% and 44.6%, respectively, with a total of 42,151 readmissions. The median time from discharge to readmission was 61 days (interquartile range, 14-168 days). The overall 12-month readmission rate remained consistently above 40% throughout the study period, with a slight drop in 2020 during the COVID-19 pandemic. Cardiovascular-related readmissions accounted for 10,318 (24.5%) of the total readmissions. Arrhythmia was the most common primary diagnosis (37.6%; atrial fibrillation/flutter in 82.4% of the cases), followed by heart failure (16.1%) and valve-related dysfunction (15.2%). Surgical valve procedure-related readmissions accounted for 24.9% of the total, with chest pain of noncardiac origin (41.0%), respiratory tract infections (16.0%), and pleural effusions (10.0%).</div></div><div><h3>Conclusions</h3><div>Nearly one-half of the patients required at least 1 readmission within 12 months of heart valve surgery, placing significant strain on the healthcare system. Cardiovascular- and procedure-related causes accounted for one-half of all readmissions.</div></div>","PeriodicalId":74032,"journal":{"name":"JTCVS open","volume":"24 ","pages":"Pages 239-255"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143854578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}