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Delays in phases of care from identification to treatment of suspicious lung nodules 从发现到治疗可疑肺结节的护理阶段的延误
JTCVS open Pub Date : 2025-04-01 DOI: 10.1016/j.xjon.2025.01.006
Nihar Rama BS , Rachel Nordgren PhD , Aliya N. Husain MD , Aditya Juloori MD , Christine M. Bestvina MD , Rajat Thawani MD , Marina Garassino MD , Septimiu Murgu MD , Ajay Wagh MD, MS , D. Kyle Hogarth MD , Carrie Barth MS , Darren Bryan MD , Mark K. Ferguson MD , Jessica Donington MD , Maria Lucia Madariaga MD
{"title":"Delays in phases of care from identification to treatment of suspicious lung nodules","authors":"Nihar Rama BS ,&nbsp;Rachel Nordgren PhD ,&nbsp;Aliya N. Husain MD ,&nbsp;Aditya Juloori MD ,&nbsp;Christine M. Bestvina MD ,&nbsp;Rajat Thawani MD ,&nbsp;Marina Garassino MD ,&nbsp;Septimiu Murgu MD ,&nbsp;Ajay Wagh MD, MS ,&nbsp;D. Kyle Hogarth MD ,&nbsp;Carrie Barth MS ,&nbsp;Darren Bryan MD ,&nbsp;Mark K. Ferguson MD ,&nbsp;Jessica Donington MD ,&nbsp;Maria Lucia Madariaga MD","doi":"10.1016/j.xjon.2025.01.006","DOIUrl":"10.1016/j.xjon.2025.01.006","url":null,"abstract":"<div><h3>Objectives</h3><div>Shorter time to lung cancer diagnosis and treatment is associated with improved outcomes. We analyzed the time spent from nodule identification to treatment to identify targets for improving the timeliness of suspicious lung nodule care in a diverse patient population.</div></div><div><h3>Methods</h3><div>This was a retrospective cohort study of patients with suspicious lung nodules (suspected clinical stage I/II primary lung cancer) at a single academic medical center (2020-2022). Patients with suspected stage III/IV or nonprimary lung cancers were excluded. Multivariable Cox regressions were performed to assess factors associated with timeliness of care.</div></div><div><h3>Results</h3><div>Of 157 patients, 59% were female, 53% were Black, and mean age was 70 ± 8.6 years. Nodules were identified incidentally (52%) or via screening (48%). Treatment was surgery in 52% and stereotactic body radiotherapy in 44%, and 10.2% were benign. Median (interquartile range) times from referral to diagnosis and from referral to treatment were 34 (22-56) days and 65 (44-84) days, respectively. Consultation to biopsy (20 [12-34] days) and diagnosis to treatment (28 [8-43] days) were the longest phases of care. Longer time from referral to diagnosis was associated with Black race and widowed status, whereas longer time from referral to treatment was associated with female gender, widowed status, frailty, body mass index greater than 18.5, Eastern Cooperative Oncology Group performance status less than 2, bronchoscopic biopsy, and treatment with stereotactic body radiotherapy.</div></div><div><h3>Conclusions</h3><div>Increased time spent in suspicious lung nodule care is associated with demographic, social, and clinical factors. The longest phases are time from consultation to biopsy and from diagnosis to treatment. Improving multidisciplinary care coordination for vulnerable patient populations could improve the timeliness of suspicious lung nodule care.</div></div>","PeriodicalId":74032,"journal":{"name":"JTCVS open","volume":"24 ","pages":"Pages 451-471"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143854868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Is timing as critical for repair of dextro-transposition of the great arteries with ventricular septal defect without outflow tract obstruction? 修复伴有室间隔缺损、无流出道梗阻的大动脉外翻时,时机是否同样重要?
JTCVS open Pub Date : 2025-04-01 DOI: 10.1016/j.xjon.2024.10.015
Muhammad Faateh MBBS , Spencer Hogue BS , Amir Mehdizadeh-Shrifi MD , Kevin Kulshrestha MD, MBE , Md Monir Hossain PhD , David G. Lehenbauer MD , David L.S. Morales MD , Awais Ashfaq MD
{"title":"Is timing as critical for repair of dextro-transposition of the great arteries with ventricular septal defect without outflow tract obstruction?","authors":"Muhammad Faateh MBBS ,&nbsp;Spencer Hogue BS ,&nbsp;Amir Mehdizadeh-Shrifi MD ,&nbsp;Kevin Kulshrestha MD, MBE ,&nbsp;Md Monir Hossain PhD ,&nbsp;David G. Lehenbauer MD ,&nbsp;David L.S. Morales MD ,&nbsp;Awais Ashfaq MD","doi":"10.1016/j.xjon.2024.10.015","DOIUrl":"10.1016/j.xjon.2024.10.015","url":null,"abstract":"<div><h3>Objective</h3><div>We sought to explore the role of timing on outcomes of the arterial switch operation + ventricular septal defect closure.</div></div><div><h3>Methods</h3><div>Neonates undergoing the arterial switch operation + ventricular septal defect closure from the Pediatric Health Information System database (2004-2022) were identified. Patients with outflow tract obstruction were excluded. Baseline features and outcomes were compared by dividing the cohort by age at the arterial switch operation + ventricular septal defect closure: very early (0-7 days), early (8-14 days), late (15-21 days), and very late (&gt;21 days). A cut-point analysis was performed to identify if an age-cutoff predicted the composite outcome (in-hospital mortality/nonhome discharge/postoperative extracorporeal membrane oxygenation/delayed sternum closure/reoperation due to bleeding).</div></div><div><h3>Results</h3><div>A total of 1005 patients were identified. The median age at repair was 6 days (interquartile range, 4-9). Repair was performed in the majority of study centers within the patient's first week of life. The distribution was very early in 652 patients (64.9%), early in 247 patients (24.6%), late in 72 patients (7.2%), and very late in 34 patients (3.4%). Late and very late groups had a greater proportion of preterm (6.3% vs 13.8% vs 23.2% vs 26.5%) and low-birthweight (5.8% vs 9% vs 21.9% vs 20%) patients (both <em>P</em> &lt; .05). In-hospital mortality was 3.1% and similar among groups (<em>P</em> &gt; .05). The identified cutoff was 8 days. In-hospital mortality was similar when comparing 0 to 8 days with more than 8 days groups (20 [2.8%] vs 11 [3.9%], <em>P</em> = .38). The more than 8 days group was more likely to develop the composite outcome (69 [24%] vs 125 [17.4%], <em>P</em> = .02), which remained significant in the multivariable analysis (adjusted odds ratio, 1.49; 95% CI, 1.02-2.15; <em>P</em> = .04). Hospitalization costs were significantly higher in the more than 8 days group ($240,742 vs $183,728, <em>P</em> &lt; .001).</div></div><div><h3>Conclusions</h3><div>This analysis of more than 1000 neonates born with dextro-transposition of the great arteries + ventricular septal defect without outflow tract obstruction revealed that most patients undergo the arterial switch operation + ventricular septal defect closure within the first week of life and had acceptable major outcomes regardless of timing. Earlier arterial switch operation + ventricular septal defect closure may confer an advantage with regard to secondary outcomes and hospitalization costs.</div></div>","PeriodicalId":74032,"journal":{"name":"JTCVS open","volume":"24 ","pages":"Pages 350-358"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143854474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Young lung cancer patients undergoing surgery: Comparison of clinicopathological characteristics and outcomes in patients aged ≤50 years versus >50 years 接受手术的年轻肺癌患者:年龄小于 50 岁与大于 50 岁患者的临床病理特征和预后比较
JTCVS open Pub Date : 2025-04-01 DOI: 10.1016/j.xjon.2024.12.008
Rachel T. Leo BA, Evert A. Sugarbaker BS, Miles McAllister BA, Anupama Singh MD, Rafael R. Barcelos MD, Ali Basil Ali MD, Raphael Bueno MD, Michael T. Jaklitsch MD, Paula Ugalde Figueroa MD, Scott J. Swanson MD
{"title":"Young lung cancer patients undergoing surgery: Comparison of clinicopathological characteristics and outcomes in patients aged ≤50 years versus >50 years","authors":"Rachel T. Leo BA,&nbsp;Evert A. Sugarbaker BS,&nbsp;Miles McAllister BA,&nbsp;Anupama Singh MD,&nbsp;Rafael R. Barcelos MD,&nbsp;Ali Basil Ali MD,&nbsp;Raphael Bueno MD,&nbsp;Michael T. Jaklitsch MD,&nbsp;Paula Ugalde Figueroa MD,&nbsp;Scott J. Swanson MD","doi":"10.1016/j.xjon.2024.12.008","DOIUrl":"10.1016/j.xjon.2024.12.008","url":null,"abstract":"<div><h3>Objective</h3><div>We investigated clinicopathologic characteristics, overall survival (OS), and locoregional recurrence-free survival of young surgical patients with non–small cell lung cancer.</div></div><div><h3>Methods</h3><div>Retrospective review of an institutional database of patients aged 50 years or younger undergoing resection for non–small cell lung cancer between January 1995 and March 2022. A control group of patients older than age 50 years was selected by stratified random sampling. Relevant characteristics were compared with Wilcoxon rank sum,χ,<sup>2</sup> and Fisher exact tests. Propensity-score weighting was used to control for confounders. OS and locoregional recurrence-free survival were analyzed with Kaplan-Meier and Cox proportional hazards regression.</div></div><div><h3>Results</h3><div>We identified 196 patients aged 50 years or younger and 232 patients older than age 50 years. Median age was 46 years (interquartile range, 43-49 years) in the younger group and 69 years (interquartile range, 63-74 years) in the older group. Younger patients were more often women, non-White, and with fewer comorbidities. They more often presented with symptoms, stage III or IV disease, and more often received neoadjuvant therapy. In unweighted analysis, younger patients showed superior OS (log-rank <em>P</em> &lt; .0001). After propensity score weighting for procedure type, histologic type, Charlson Comorbidity Index, and smoking status, there was no significant difference in OS at 5 years between younger and older groups (70.62% vs 72.99%; weighted log-rank <em>P</em> = .084). Younger patients showed superior OS (weighted log-rank <em>P</em> = .0006) and locoregional recurrence-free survival (weighted log-rank <em>P</em> = .017) for clinical stage I, but not any other stage. lymphovascular invasion was an independent risk factor for worsened OS and locoregional recurrence-free survival across ages.</div></div><div><h3>Conclusions</h3><div>Recognizing lung cancer as a differential diagnosis for patients aged 50 years or younger is crucial because this group shows superior outcomes for stage I disease. Lymphovascular invasion is an independent prognostic risk factor across age groups.</div></div>","PeriodicalId":74032,"journal":{"name":"JTCVS open","volume":"24 ","pages":"Pages 409-422"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143854480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optimal treatment for nonsevere coronary artery disease in valve surgeries: Concurrent coronary artery bypass grafting or postoperative medical therapy? 瓣膜手术中非严重冠状动脉疾病的最佳治疗:并发冠状动脉旁路移植术还是术后药物治疗?
JTCVS open Pub Date : 2025-04-01 DOI: 10.1016/j.xjon.2025.01.011
Li Ding MD, PhD
{"title":"Optimal treatment for nonsevere coronary artery disease in valve surgeries: Concurrent coronary artery bypass grafting or postoperative medical therapy?","authors":"Li Ding MD, PhD","doi":"10.1016/j.xjon.2025.01.011","DOIUrl":"10.1016/j.xjon.2025.01.011","url":null,"abstract":"","PeriodicalId":74032,"journal":{"name":"JTCVS open","volume":"24 ","pages":"Pages 256-263"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143854579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Distal anastomosis new entry tear in acute type A aortic dissection: A risk factor for distal aortic reoperation 急性A型主动脉夹层远端吻合新入口撕裂:主动脉远端再手术的危险因素
JTCVS open Pub Date : 2025-04-01 DOI: 10.1016/j.xjon.2025.02.016
Rana-Armaghan Ahmad BS , Prabhvir Marway MD , Carlos Alberto Campello Jorge MD , Katelyn Monaghan BS , Divyaam Satija BS , Carol Ling MS , Shinichi Fukuhara MD , Himanshu Patel MD , G. Michael Deeb MD , Nicholas Burris MD , Bo Yang MD, PhD
{"title":"Distal anastomosis new entry tear in acute type A aortic dissection: A risk factor for distal aortic reoperation","authors":"Rana-Armaghan Ahmad BS ,&nbsp;Prabhvir Marway MD ,&nbsp;Carlos Alberto Campello Jorge MD ,&nbsp;Katelyn Monaghan BS ,&nbsp;Divyaam Satija BS ,&nbsp;Carol Ling MS ,&nbsp;Shinichi Fukuhara MD ,&nbsp;Himanshu Patel MD ,&nbsp;G. Michael Deeb MD ,&nbsp;Nicholas Burris MD ,&nbsp;Bo Yang MD, PhD","doi":"10.1016/j.xjon.2025.02.016","DOIUrl":"10.1016/j.xjon.2025.02.016","url":null,"abstract":"<div><h3>Objective</h3><div>To identify predictive factors for the occurrence of a distal anastomosis new entry tear (DANE) in patients who underwent hemiarch replacement after acute type A aortic dissection (ATAAD) and examine the association of DANE with distal aortic reoperation.</div></div><div><h3>Methods</h3><div>Between 1996 and March 2021, 434 patients underwent hemiarch replacement for DeBakey I ATAAD, of whom 327 patients had adequate postoperative imaging. Based on the presence of DANE on postoperative computed tomography angiography, patients were divided into the DANE group (n = 81) and the no-DANE group (n = 246). Primary outcomes were the cumulative incidence of distal aortic reoperation and the risk factors for DANE.</div></div><div><h3>Results</h3><div>Most perioperative characteristics and outcomes, including age, sex, malperfusion syndromes, aortic diameters, and operative mortality were similar in the 2 groups. Using death as a competing factor, the 10-year cumulative incidence of distal aortic reoperation was higher in the DANE group compared to the no-DANE group (30% vs 12%; <em>P</em> = .0001). The hazard ratio for DANE in distal reoperations was 2.28 (<em>P</em> = .005). A multivariable regression model showed that having an aortic surgeon was protective against DANE compared to having a nonaortic surgeon (odds ratio [OR], 0.29; <em>P</em> = .05) and identified branch dissection (OR, 2.42; <em>P</em> = .002) as a risk factor for the occurrence of DANE. Connective tissue disease and large-bore suture (4-0 vs 5-0) were not associated with DANE.</div></div><div><h3>Conclusions</h3><div>Optimizing surgical techniques to prevent DANE in ATAAD repair may prevent the need for reoperation on the distal aorta in DeBakey type I ATAAD.</div></div>","PeriodicalId":74032,"journal":{"name":"JTCVS open","volume":"24 ","pages":"Pages 77-84"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143854676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preclinical experience with cisplatin, gemcitabine, and doxorubicin in pulmonary suffusion 顺铂、吉西他滨和阿霉素治疗肺灌注的临床前经验
JTCVS open Pub Date : 2025-04-01 DOI: 10.1016/j.xjon.2024.12.012
Lindsay J. Nitsche BS , Leslie Curtin DVM , Sandra Sexton DVM , Thaer Khoury MD , Joshua D. Prey MS , Sai Yendamuri MD , Todd L. Demmy MD
{"title":"Preclinical experience with cisplatin, gemcitabine, and doxorubicin in pulmonary suffusion","authors":"Lindsay J. Nitsche BS ,&nbsp;Leslie Curtin DVM ,&nbsp;Sandra Sexton DVM ,&nbsp;Thaer Khoury MD ,&nbsp;Joshua D. Prey MS ,&nbsp;Sai Yendamuri MD ,&nbsp;Todd L. Demmy MD","doi":"10.1016/j.xjon.2024.12.012","DOIUrl":"10.1016/j.xjon.2024.12.012","url":null,"abstract":"<div><h3>Background</h3><div>Because suffusion amplifies lung chemotherapy while limiting systemic toxicity, we tested candidate drugs for treating human lung cancers and pulmonary metastases.</div></div><div><h3>Methods</h3><div>Immature beagle dogs underwent thoracotomy for unilateral lung suffusion of cisplatin (0.125-2 mg/kg; n = 19), doxorubicin (3.75-7.5 mg/kg; n = 7), gemcitabine (168.75 mg/kg; n = 5), or saline (n = 3). After ipsilateral lung circulation isolation and drainage, pulmonary artery chemotherapy was injected, dwelled for 30 minutes, and then aspirated. Bilateral lung biopsies and serum samples assessed delivery and leak. After lung reperfusion, animals recovered for 30 days with scheduled monitoring of vital signs, weights, and behaviors. At experiment termination, necropsy histopathologic tissue analyses assessed tolerability.</div></div><div><h3>Results</h3><div>All 32 animals recovered, except 1 with lung torsion and 2 with pulmonary toxicity that required early euthanasia. Serum concentrations during suffusion for cisplatin (135 ng/mL), doxorubicin (undetectable), and gemcitabine (1452 ng/mL) indicated minimal systemic leakage. Cisplatin escalations showed uniform suffusion deliveries (100% fibrosis at a 100% systemic chemotherapy dose), which was then reduced to a nondamaging 25% threshold. When the equivalent dose of doxorubicin was used, toxicity occurred, but 12.5% (2.5-fold amplification of local delivery) was well tolerated. Gemcitabine, like cisplatin, caused minimal toxicity at 25% of the systemic dose (5-fold amplification). Optimized doses caused no hematologic or metabolic derangements and necropsies showed no gross organ injury other than adhesions. Histopathology demonstrated multifocal ipsilateral lung fibrotic changes without contralateral or extrapulmonary pathology.</div></div><div><h3>Conclusions</h3><div>While suffusion delivery of the vesicant doxorubicin was tolerated less well than cisplatin and gemcitabine, all appear to be safe and feasible for human trials.</div></div>","PeriodicalId":74032,"journal":{"name":"JTCVS open","volume":"24 ","pages":"Pages 484-495"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143854869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Research productivity among applicants who matched into an integrated thoracic surgery residency program: A bibliographic review 符合综合胸外科住院医师计划的申请人的研究效率:参考文献回顾
JTCVS open Pub Date : 2025-02-01 DOI: 10.1016/j.xjon.2024.11.017
Nika Samadzadeh Tabrizi MD , Michelle Shen BS , Alexander D. Shapeton MD , Isha Doshi MD , Junyi Liu BS , Thomas Fabian MD , Patrick Chan MD
{"title":"Research productivity among applicants who matched into an integrated thoracic surgery residency program: A bibliographic review","authors":"Nika Samadzadeh Tabrizi MD ,&nbsp;Michelle Shen BS ,&nbsp;Alexander D. Shapeton MD ,&nbsp;Isha Doshi MD ,&nbsp;Junyi Liu BS ,&nbsp;Thomas Fabian MD ,&nbsp;Patrick Chan MD","doi":"10.1016/j.xjon.2024.11.017","DOIUrl":"10.1016/j.xjon.2024.11.017","url":null,"abstract":"<div><h3>Background</h3><div>Research productivity is an important factor in candidate selection by integrated thoracic surgery residency programs, and thus tracking the research output of applicants who match into an integrated program is necessary. This study sought to examine the research productivity of matched integrated applicants prior to residency and to assess demographic, bibliographic, and institutional variables associated with continued research productivity during residency.</div></div><div><h3>Methods</h3><div>Bibliographic records of applicants who matched into an integrated thoracic surgery residency program from 2015 to 2022 were reviewed manually (eg, PubMed/MEDLINE, Scopus, Google Scholar, ResearchGate) to identify studies published up to January 2024. Publications were stratified by publication type and first authorship relative to the applicants’ match year. Individuals were analyzed by demographics, medical school ranking, and affiliated residency program research infrastructure.</div></div><div><h3>Results</h3><div>A total of 300 matched integrated applicants were identified. Among applicants who matched into an integrated program, the number of total (<em>P</em> = .001) and first-authorship (<em>P</em> = .006) publications prior to residency increased significantly from 2015 to 2022. Over the same period, the rates of total (<em>P</em> = .2) and first-authorship (<em>P</em> = .3) publications during residency remained relatively unchanged. Matched integrated applicants with a higher number of total and first-authorship publications prior to residency had higher rates of total publications (1.17; 95% confidence interval [CI], 1.09-1.25; <em>P</em> &lt; .001) and first-authorship publications (1.19; 95% CI, 1.13-1.26; <em>P</em> &lt; .001) publications during residency.</div></div><div><h3>Conclusions</h3><div>Research productivity among applicants who matched into an integrated thoracic surgery residency program from 2015 to 2022 has increased and is a strong predictor of sustained scholarly output during residency.</div></div>","PeriodicalId":74032,"journal":{"name":"JTCVS open","volume":"23 ","pages":"Pages 369-378"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143465078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reply: Continental developments in African cardiothoracic surgery 答复:非洲心胸外科的大陆发展
JTCVS open Pub Date : 2025-02-01 DOI: 10.1016/j.xjon.2024.12.009
Victory B. Effiom MD , Anayo J. Michael MD , Fatma K. Ahmed MD , Achanga Bs. Anyinkeng MD , Jonas L. Ibekwe MD , Abdullah K. Alassiri MD , Victor O. Femi-Lawal MD , Eric E. Vinck MD
{"title":"Reply: Continental developments in African cardiothoracic surgery","authors":"Victory B. Effiom MD ,&nbsp;Anayo J. Michael MD ,&nbsp;Fatma K. Ahmed MD ,&nbsp;Achanga Bs. Anyinkeng MD ,&nbsp;Jonas L. Ibekwe MD ,&nbsp;Abdullah K. Alassiri MD ,&nbsp;Victor O. Femi-Lawal MD ,&nbsp;Eric E. Vinck MD","doi":"10.1016/j.xjon.2024.12.009","DOIUrl":"10.1016/j.xjon.2024.12.009","url":null,"abstract":"","PeriodicalId":74032,"journal":{"name":"JTCVS open","volume":"23 ","pages":"Page 387"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143465081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Routine use of jejunostomy tubes after esophagectomy: The good, the bad, and the ugly! 食管切除术后空肠造口管的常规使用:好的、坏的和丑陋的!
JTCVS open Pub Date : 2025-02-01 DOI: 10.1016/j.xjon.2024.09.032
Sadia Tasnim MD, MS , Siva Raja MD, PhD , Sadhvika Ramji MD , Rachel NeMoyer MD, MPH , Eugene H. Blackstone MD , Andrew J. Toth MS , John O. Barron MD , Daniel P. Raymond MD , Sudish C. Murthy MD, PhD , Monisha Sudarshan MD, MPH
{"title":"Routine use of jejunostomy tubes after esophagectomy: The good, the bad, and the ugly!","authors":"Sadia Tasnim MD, MS ,&nbsp;Siva Raja MD, PhD ,&nbsp;Sadhvika Ramji MD ,&nbsp;Rachel NeMoyer MD, MPH ,&nbsp;Eugene H. Blackstone MD ,&nbsp;Andrew J. Toth MS ,&nbsp;John O. Barron MD ,&nbsp;Daniel P. Raymond MD ,&nbsp;Sudish C. Murthy MD, PhD ,&nbsp;Monisha Sudarshan MD, MPH","doi":"10.1016/j.xjon.2024.09.032","DOIUrl":"10.1016/j.xjon.2024.09.032","url":null,"abstract":"<div><h3>Objective</h3><div>The study objective was to assess adverse events, readmissions, and resource use associated with routine jejunostomy tube placement after esophagectomy.</div></div><div><h3>Methods</h3><div>From September 2018 to October 2021, 215 patients, with a median age of 65 years and a median body mass index of 27 kg/m<sup>2</sup>, underwent routine jejunostomy tube placement during esophagectomy. J-tube–related adverse events were collected from date of surgery to date of removal and categorized as (1) nonserious, resource-nonintensive (eg, skin irritations, discomfort); (2) nonserious, resource-intensive (eg, infection, clogged, and dislodged tubes); and (3) serious, resource-intensive (eg, bowel obstruction, volvulus, tube feed intolerance). Esophagectomy and jejunostomy tube–related readmissions and nutritional markers were also assessed during the jejunostomy tube indwelling time.</div></div><div><h3>Results</h3><div>Of the 215 patients, 177 experienced 459 events documented during 372 healthcare encounters. Nonserious adverse events occurred within 4 to 6 weeks after surgery with the peak at 3 to 4 weeks. Serious adverse events (4, 0.9%) were rare and occurred mostly in the acute postoperative period. Thirty-five patients (16%) were readmitted during their jejunostomy tube indwelling time, of whom 14 (7%) were readmitted due to jejunostomy tube–related issues. Jejunostomy tube–related events were not predictors for readmission. Nutritional status stabilized within 30 days of surgery.</div></div><div><h3>Conclusions</h3><div>Serious adverse events after routine jejunostomy tube placement postesophagectomy are rare and occur mostly in the immediate postoperative period. Nonserious adverse events are more common and can be resource-intensive, providing an opportunity for improvement. Readmissions for jejunostomy tube complications are low. Nutritional status is appropriately maintained with supplemental jejunostomy tube feeding postesophagectomy. These findings suggest that routine jejunostomy tube placement at the time of esophagectomy can be a reasonable management strategy as part of a delayed feeding algorithm.</div></div>","PeriodicalId":74032,"journal":{"name":"JTCVS open","volume":"23 ","pages":"Pages 276-287"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143465188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tricuspid valve replacement with bioprostheses: Which type fits best? 生物假体置换三尖瓣:哪种类型最适合?
JTCVS open Pub Date : 2025-02-01 DOI: 10.1016/j.xjon.2024.11.003
Uberto Bortolotti MD
{"title":"Tricuspid valve replacement with bioprostheses: Which type fits best?","authors":"Uberto Bortolotti MD","doi":"10.1016/j.xjon.2024.11.003","DOIUrl":"10.1016/j.xjon.2024.11.003","url":null,"abstract":"","PeriodicalId":74032,"journal":{"name":"JTCVS open","volume":"23 ","pages":"Page 109"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143464402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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