Y. Shimizu, H. Yamanashi, Jun Miyata, Midori Takada, Y. Noguchi, Yukiko Honda, F. Nonaka, Seiko Nakamichi, Yasuhiro Nagata, T. Maeda
{"title":"Serum Calcium Level and Functional Atherosclerosis in Relation to Human T-Cell Leukemia Virus 1 Infection in Older Individuals","authors":"Y. Shimizu, H. Yamanashi, Jun Miyata, Midori Takada, Y. Noguchi, Yukiko Honda, F. Nonaka, Seiko Nakamichi, Yasuhiro Nagata, T. Maeda","doi":"10.3390/jvd2030025","DOIUrl":"https://doi.org/10.3390/jvd2030025","url":null,"abstract":"Serum calcium levels are known to influence vascular function. Cells infected with human T-cell leukemia virus 1 (HTLV-1) impact serum calcium levels and also affect the endothelium. Since a damaged endothelium causes functional atherosclerosis, serum calcium levels in HTLV-1 carriers may be positively associated with functional atherosclerosis. This cross-sectional study enrolled 1694 Japanese individuals aged 60 to 89 years. Functional atherosclerosis was defined as a cardio-ankle vascular index (CAVI) ≥ 9.0. Logistic regression analysis was used to evaluate the relationship between HTLV-1 carrier status and both serum calcium level and functional atherosclerosis. Even after adjusting for known confounding factors, the serum calcium level was significantly positively associated with functional atherosclerosis only in asymptomatic HTLV-1 carriers. The fully adjusted odds ratio and 95% confidence interval of functional atherosclerosis in relation to a one-standard-deviation increment of serum calcium level (0.4 mg/dL in both men and women) were 1.54 (1.18, 2.01) for HTLV-1 carriers (n = 322) and 0.99 (0.87, 1.13) for HTLV-1 non-carriers (n = 1372), respectively. The serum calcium level was positively associated with functional atherosclerosis only among older carriers of HTLV-1 infection. This finding can help effectively estimate the risk of functional atherosclerosis in asymptomatic HTLV-1 carriers.","PeriodicalId":74009,"journal":{"name":"Journal of vascular diseases","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82523783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Shchekochikhin, O. Vinogradskaya, Evgeniia Bublik, M. Shmyreva, G. Koroba, A. Farmanov, I. Aslanidis, D. Pursanova, Veronica Manukova, A. Zilov, A. Zhivov
{"title":"Zoledronate-Induced Large Vessel Vasculitis Diagnosed by PET/CT","authors":"D. Shchekochikhin, O. Vinogradskaya, Evgeniia Bublik, M. Shmyreva, G. Koroba, A. Farmanov, I. Aslanidis, D. Pursanova, Veronica Manukova, A. Zilov, A. Zhivov","doi":"10.3390/jvd2030024","DOIUrl":"https://doi.org/10.3390/jvd2030024","url":null,"abstract":"Bisphosphonates remain a first-line treatment for osteoporosis. The most-widely used is zoledronate, which is well tolerated by most patients, but may rarely cause acute inflammatory reactions, which resemble those of large vessel vasculitis (LVV). We report a third case of LVV associated with zoledronic acid infusion, presenting with a 2-week history of fever up to 40 °C, flu-like symptoms, left jaw pain, myalgia, arthralgia, ankle stiffness in the morning, and intermittent claudication, diagnosed by the hybrid imaging modality 18F-FDG PET/CT with isolated lower extremity involvement and successfully treated with glucocorticoids.","PeriodicalId":74009,"journal":{"name":"Journal of vascular diseases","volume":"70 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77160538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Martínez‐Sellés, Jorge García Carreño, J. Martínez-Solano, I. Sousa, M. Juárez-Fernández
{"title":"Survey on Cardiogenic Shock and the Use of ECMO and Impella in Spanish Cardiac Critical Care Units","authors":"M. Martínez‐Sellés, Jorge García Carreño, J. Martínez-Solano, I. Sousa, M. Juárez-Fernández","doi":"10.3390/jvd2030022","DOIUrl":"https://doi.org/10.3390/jvd2030022","url":null,"abstract":"Background: Previous studies suggest variability in the management of cardiogenic shock (CS). Methods: An anonymous survey was sent to Spanish hospitals. Results: We obtained 50 answers, mainly from cardiologists (36–72%). The annual average of ECMOs is 16.7 ± 11.3 applications in CS patients and of Impellas is 8.7 ± 8.3 applications in CS patients. Intra-aortic balloon counterpulsation is used in the majority of CS ECMOs (31–62%), and Impella is used in 7 (14%). In 36 (72%) cases, ECMO is used as a treatment for cardiac arrest. In 10 cases, ECMO removal is percutaneous (20%). In 25 (50%) cases, age is a relative contraindication; 17 have a mobile ECMO team (34%); and 23 (46%) have received ECMO patients from other centers in the last year. Pre-purged ECMO is only used in 16 (32%). ECMO implantation is carried out under ultrasound guidance in 31 (62%), only with angiography in 3 (6%) and with both in 11 (22%). The Swan–Ganz catheter is used routinely in 8 (16%), only in doubtful cases in 24 (48%), and in most cases in 8 (16%). The ECMO awake strategy is used little or not at all in 28 (56%), in selected cases in 17 (34%), and routinely in 5 (10%). Conclusion: Our study shows a huge variation in the management of patients with CS.","PeriodicalId":74009,"journal":{"name":"Journal of vascular diseases","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78464260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eric M. Teichner, Robert C. Subtirelu, Arjun B. Ashok, Yvonne Su, Victoria A. Anderson, Milo Writer, Omar Al-Daoud, Miraziz Ismoilov, William Y. Raynor, T. Werner, P. Høilund-Carlsen, A. Alavi, M. Revheim
{"title":"The Emerging Role of NaF-PET/CT in Detecting Vascular Microcalcification in the Pathogenesis of Neurological Dysfunction","authors":"Eric M. Teichner, Robert C. Subtirelu, Arjun B. Ashok, Yvonne Su, Victoria A. Anderson, Milo Writer, Omar Al-Daoud, Miraziz Ismoilov, William Y. Raynor, T. Werner, P. Høilund-Carlsen, A. Alavi, M. Revheim","doi":"10.3390/jvd2030023","DOIUrl":"https://doi.org/10.3390/jvd2030023","url":null,"abstract":"Cerebrovascular disease (CVD) is a global health concern, and early detection is crucial for effective intervention. This case report presents a 31-year-old male patient with multiple cardiac risk factors who underwent positron emission tomography/computed tomography (PET/CT) with 18F-sodium fluoride (NaF) and 18F-fluorodeoxyglucose (FDG) to evaluate for the presence and degree of atherosclerosis in the aorta, carotid arteries, coronary arteries, iliac arteries, and the femoral arteries. Elevated NaF uptake within the bilateral carotid arteries signified substantial ongoing vascular microcalcification. Reduced global brain metabolism and region-specific hypometabolism measured with FDG PET indicated potential cerebrovascular mechanisms that may be influencing neurological function. The findings highlight the potential of emerging PET tracers, such as NaF, to improve the diagnostic accuracy and therapeutic management of CVD. This case emphasizes the importance of a comprehensive diagnostic approach as well as continued investigation into CVD pathophysiology using PET-based techniques, which may guide the development of innovative therapeutic strategies.","PeriodicalId":74009,"journal":{"name":"Journal of vascular diseases","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75959521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
David Costa, Nicola Ielapi, R. Minici, E. Bevacqua, S. Ciranni, L. Cristodoro, G. Torcia, M. D. Di Taranto, U. Bracale, M. Andreucci, R. Serra
{"title":"Metalloproteinases between History, Health, Disease, and the Complex Dimension of Social Determinants of Health","authors":"David Costa, Nicola Ielapi, R. Minici, E. Bevacqua, S. Ciranni, L. Cristodoro, G. Torcia, M. D. Di Taranto, U. Bracale, M. Andreucci, R. Serra","doi":"10.3390/jvd2030021","DOIUrl":"https://doi.org/10.3390/jvd2030021","url":null,"abstract":"Metalloproteinases (MPs) belong to the superfamily of zinc endopeptidases, which are called metzincins. Three families of MPs have been studied in healthy and diseased conditions in humans. The first study on MPs was published in 1962, and following that, several studies characterized their activity and their effect on health and disease. Several diseases have been related to MPs, such as cardiovascular disease, cancer, inflammatory diseases, gynecological disorders, and others. Moreover, tissue inhibitors of metalloproteinases (TIMPs) have been widely studied, and drugs and artificial molecules that could target MP activity have been evaluated. MPs are relevant to public health because of their role in several diseases and, most of all, their role as biomarkers that also impact the quality of life and the psychosocial dimension of affected patients. In this context, new pathways to precision health and precision medicine have been opened in the area of MPs. This review describes, from the initial studies, the complex dimensions of MPs and related issues centered on health and disease dimensions.","PeriodicalId":74009,"journal":{"name":"Journal of vascular diseases","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86062126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Cuenca‐Martínez, E. Muñoz-Gómez, S. Mollà-Casanova, N. Sempere-Rubio
{"title":"Effects of Movement Representation Strategies on Cardiovascular Disease: A Literature Review","authors":"F. Cuenca‐Martínez, E. Muñoz-Gómez, S. Mollà-Casanova, N. Sempere-Rubio","doi":"10.3390/jvd2030019","DOIUrl":"https://doi.org/10.3390/jvd2030019","url":null,"abstract":"Motor imagery (MI) and action observation (AO) techniques are two movement representation strategies that are widely used in multiple fields of study. MI is defined as the cognitive skill that involves the representation of an action, internally, without actual motor execution. AO training evokes internally, and in real time, a simulation of the actual motor gestures that the observer is visually perceiving. Both cognitive processes cause an activation of the brain areas related to the planning, adjustment, and automation of voluntary movement in a similar way as when the action is carried out in a real way. Movement representation strategies have shown that they can be a very useful complement to physical practice to improve some particularly relevant aspects in neurological and musculoskeletal patients. In this narrative review, we discuss the effect that the implementation of these motion representation strategies might have on patients with cardiovascular disease. At the cardiovascular level, MI and AO training should be considered as interventional tools for the management of these patients. With these clinical tools, we could try to improve the generation of cardiopulmonary adaptations, improve exercise tolerability, and also increase functionality. However, more research is needed in this field where these clinical tools are combined with cardiac rehabilitation programs to see if the clinical effect is greater than cardiac rehabilitation programs in isolation.","PeriodicalId":74009,"journal":{"name":"Journal of vascular diseases","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74023054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Brassel, M. Schlunz-Hendann, M. Scholz, Robert Lucaciu, Chunfu Fan, V. Koch, D. Grieb, F. Brevis Nunez, S. Schwarz, C. Sommer
{"title":"Neurointerventional Treatment of Vein of Galen Malformation (VGM): A Structured Review with a Proposal for the Comparison of Outcome Quality","authors":"F. Brassel, M. Schlunz-Hendann, M. Scholz, Robert Lucaciu, Chunfu Fan, V. Koch, D. Grieb, F. Brevis Nunez, S. Schwarz, C. Sommer","doi":"10.3390/jvd2020018","DOIUrl":"https://doi.org/10.3390/jvd2020018","url":null,"abstract":"Background: Vein of Galen malformation (VGM) is a congenital intracranial vascular anomaly consisting of arteriovenous fistulas and/or malformations between various arterial feeders and the median prosencephalic vein of Markowski (MPV). Despite its rare occurrence, VGM is of particular clinical relevance, as the excessive intracranial shunt volume leads to high mortality without appropriate treatment. Methods: The objective of this article is to review the published data on neurointerventional treatment and compare outcome quality in the included studies. Eight studies were included and synthesized. One study was multicentric and the rest were retrospective monocentric (level 4 evidence studies according to the Oxford Centre for Evidence-based Medicine). Results: The total number of included patients was 480 and patient age ranged from 1 day to 18 years. Mild or severe heart failure, hydrocephalus, and other reasons led to the indication for neurointerventional treatment, which was performed in all studies in the form of embolization. Under consideration of the introduced semiquantitative multidimensional scoring system, the highest total score, i.e., the best outcome quality, was found for the study “Houston” 2002–2018 (19 points) and the study “Duisburg” 2001–2010 (19 points). Conclusions: Neurointerventional treatment represents the essential pillar in the interdisciplinary management of patients with VGM, although standardization is lacking—based on the results of the structured review. As complementary treatments, pediatric critical care is mandatory and includes medical hemodynamic stabilization.","PeriodicalId":74009,"journal":{"name":"Journal of vascular diseases","volume":"6 2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85650236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Divine C Nwafor, Brandon D Kirby, Jacob D Ralston, Mark A Colantonio, Elochukwu Ibekwe, Brandon Lucke-Wold
{"title":"Neurocognitive Sequelae and Rehabilitation after Subarachnoid Hemorrhage: Optimizing Outcomes.","authors":"Divine C Nwafor, Brandon D Kirby, Jacob D Ralston, Mark A Colantonio, Elochukwu Ibekwe, Brandon Lucke-Wold","doi":"10.3390/jvd2020014","DOIUrl":"10.3390/jvd2020014","url":null,"abstract":"<p><p>Subarachnoid hemorrhage (SAH) is a medical emergency that requires immediate intervention. The etiology varies between cases; however, rupture of an intracranial aneurysm accounts for 80% of medical emergencies. Early intervention and treatment are essential to prevent long-term complications. Over the years, treatment of SAH has drastically improved, which is responsible for the rapid rise in SAH survivors. Post-SAH, a significant number of patients exhibit impairments in memory and executive function and report high rates of depression and anxiety that ultimately affect daily living, return to work, and quality of life. Given the rise in SAH survivors, rehabilitation post-SAH to optimize patient outcomes becomes crucial. The review addresses the current rehabilitative strategies to combat the neurocognitive and behavioral issues that may arise following SAH.</p>","PeriodicalId":74009,"journal":{"name":"Journal of vascular diseases","volume":"2 2","pages":"197-211"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9562917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical Use of Direct Oral Anticoagulants and Reversal: Consideration for Vascular Surgeons","authors":"A. Houben, Vincent Bonhomme, M. Senard","doi":"10.3390/jvd2020017","DOIUrl":"https://doi.org/10.3390/jvd2020017","url":null,"abstract":"Since their first approval in 2010, direct oral anticoagulants (DOACs) have become attractive for anticoagulant treatment. DOACs are indicated for the prevention and treatment of several cardiovascular conditions and have now emerged as leading therapeutic options. Every year, large number of patients receiving DOACs routinely are scheduled for invasive surgical procedures and need specific perioperative management. Moreover, recently published trials have provided arguments for a larger future use of DOACs, including during the postoperative period after vascular surgery and for high-risk cardiovascular patients. In this communication, we discuss the perioperative management of DOACs for patients undergoing vascular surgery.","PeriodicalId":74009,"journal":{"name":"Journal of vascular diseases","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91209999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Rohman, Yoga Waranugraha, Ainun Nizar Masbuchin, S. S. Baskoro, Lintang Widya Sishartami, Bunga Bella Pratiwi
{"title":"Coronary In-Stent Restenosis Predictors following Drug-Eluting Stent Implantation: A Meta-analysis Study","authors":"M. Rohman, Yoga Waranugraha, Ainun Nizar Masbuchin, S. S. Baskoro, Lintang Widya Sishartami, Bunga Bella Pratiwi","doi":"10.37766/inplasy2023.5.0092","DOIUrl":"https://doi.org/10.37766/inplasy2023.5.0092","url":null,"abstract":"Numerous studies have investigated in-stent restenosis (ISR) predictors in first-generation drug-eluting stents (DESs), but only a few have investigated second-generation DESs. We aimed to investigate the ISR predictors following a successful DES implantation in coronary artery disease (CAD) patients. A systematic review and meta-analysis study was conducted. Diabetes mellitus (DM) (OR 1.47; 95% CI 1.19 to 1.83; p < 0.01), family history of CAD (OR 1.26; 95% CI 1.03 to 1.55; p 0.03), and smoking (OR 1.23; 95% CI 1.02 to 1.48; p 0.03) were the strong predictors for the DES-ISR. The DES-ISR was more common in DESs with smaller stent diameter (MD −0.12; 95% CI −0.16 to −0.08; p < 0.01) and longer stent length (MD 2.24; 95% CI 1.36 to 3.13; p < 0.01). Angiography characteristics, including multi-vessel disease (MVD) (OR 1.45; 95% CI 1.07 to 1.97; p 0.02), type B2/C lesions (OR 1.56; 95% CI 1.06 to 2.30; p 0.02), and type C lesion (OR 1.33; 95% CI 1.09 to 1.62; p < 0.01), were also associated with DES-ISR. We confirmed that DM, family history of CAD, smoking, MVD, smaller stent diameter, longer stent length, and type B2 or C lesions were proven to be ISR predictors following DES implantation.","PeriodicalId":74009,"journal":{"name":"Journal of vascular diseases","volume":"154 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86287447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}