D. Shchekochikhin, O. Vinogradskaya, Evgeniia Bublik, M. Shmyreva, G. Koroba, A. Farmanov, I. Aslanidis, D. Pursanova, Veronica Manukova, A. Zilov, A. Zhivov
{"title":"Zoledronate-Induced Large Vessel Vasculitis Diagnosed by PET/CT","authors":"D. Shchekochikhin, O. Vinogradskaya, Evgeniia Bublik, M. Shmyreva, G. Koroba, A. Farmanov, I. Aslanidis, D. Pursanova, Veronica Manukova, A. Zilov, A. Zhivov","doi":"10.3390/jvd2030024","DOIUrl":null,"url":null,"abstract":"Bisphosphonates remain a first-line treatment for osteoporosis. The most-widely used is zoledronate, which is well tolerated by most patients, but may rarely cause acute inflammatory reactions, which resemble those of large vessel vasculitis (LVV). We report a third case of LVV associated with zoledronic acid infusion, presenting with a 2-week history of fever up to 40 °C, flu-like symptoms, left jaw pain, myalgia, arthralgia, ankle stiffness in the morning, and intermittent claudication, diagnosed by the hybrid imaging modality 18F-FDG PET/CT with isolated lower extremity involvement and successfully treated with glucocorticoids.","PeriodicalId":74009,"journal":{"name":"Journal of vascular diseases","volume":"70 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of vascular diseases","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3390/jvd2030024","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Bisphosphonates remain a first-line treatment for osteoporosis. The most-widely used is zoledronate, which is well tolerated by most patients, but may rarely cause acute inflammatory reactions, which resemble those of large vessel vasculitis (LVV). We report a third case of LVV associated with zoledronic acid infusion, presenting with a 2-week history of fever up to 40 °C, flu-like symptoms, left jaw pain, myalgia, arthralgia, ankle stiffness in the morning, and intermittent claudication, diagnosed by the hybrid imaging modality 18F-FDG PET/CT with isolated lower extremity involvement and successfully treated with glucocorticoids.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
