Journal of psychopathology and clinical science最新文献

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Prospective examination of mechanisms linking minority stress and anxious/depressed affect at the event level: The roles of emotion regulation strategies and proximal minority stressors. 在事件层面对少数群体压力与焦虑/抑郁情绪之间的联系机制进行前瞻性研究:情绪调节策略和近端少数群体压力源的作用。
Journal of psychopathology and clinical science Pub Date : 2024-02-01 Epub Date: 2023-12-14 DOI: 10.1037/abn0000882
Christina Dyar
{"title":"Prospective examination of mechanisms linking minority stress and anxious/depressed affect at the event level: The roles of emotion regulation strategies and proximal minority stressors.","authors":"Christina Dyar","doi":"10.1037/abn0000882","DOIUrl":"10.1037/abn0000882","url":null,"abstract":"<p><strong>Background: </strong>While studies have linked sexual minority stress with anxious/depressed affect, few studies have prospectively examined how mechanistic processes linking minority stress and anxious/depressed affect unfold in near-real time. Furthermore, studies of mechanisms have focused exclusively on rumination and proximal minority stressors (e.g., internalized stigma). This limits our understanding of other potential mechanisms, such as decreases in the use of reappraisal and reflection, strategies associated with reducing anxious/depressed affect.</p><p><strong>Method: </strong>We used data from a 30-day ecological momentary assessment study with 429 sexual minority women and gender diverse sexual minorities assigned female at birth to determine whether concurrent and prospective event-level associations between minority stress and anxious/depressed affect were mediated by changes in six emotion regulation strategies, perceived coping efficacy, and proximal stressors.</p><p><strong>Results: </strong>In partially lagged analyses, when individuals experienced enacted or internalized stigma, they reported increased rumination and expressive suppression on the same day, which predicted increases in anxious/depressed affect into the next day. Decreases in reappraisal also mediated partially lagged associations between internalized stigma and anxious/depressed affect. Fully lagged mediation was only demonstrated for rumination as a mechanism linking internalized stigma with anxious/depressed affect. We found concurrent evidence for other mechanisms (i.e., perceived coping efficacy, reflection, internalized stigma, and rejection sensitivity).</p><p><strong>Conclusions: </strong>Results provided support for the roles of rumination and expressive suppression as mechanisms of linking minority stress and anxious/depressed affect. The concurrent evidence for other mechanisms suggests that future research with more temporal resolution is necessary to determine the temporality and directionality of these associations. (PsycInfo Database Record (c) 2024 APA, all rights reserved).</p>","PeriodicalId":73914,"journal":{"name":"Journal of psychopathology and clinical science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10842229/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138809552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The affective benefits of real-world exploration during the COVID-19 pandemic. 在 COVID-19 大流行期间,真实世界探索带来的情感益处。
Journal of psychopathology and clinical science Pub Date : 2024-02-01 Epub Date: 2023-12-14 DOI: 10.1037/abn0000888
T Rick Reneau, William J Villano, Brittany A Jaso, Aaron S Heller
{"title":"The affective benefits of real-world exploration during the COVID-19 pandemic.","authors":"T Rick Reneau, William J Villano, Brittany A Jaso, Aaron S Heller","doi":"10.1037/abn0000888","DOIUrl":"10.1037/abn0000888","url":null,"abstract":"<p><p>Increasing daily exploration is linked to improvements in affective well-being. However, COVID-19 elevated uncertainty when leaving the home, altering the risk-reward of balance of geospatial novelty. To this end, we simultaneously collected real-world geospatial tracking and experience sampling of emotion, prior to and during the first year of the pandemic in 630 individuals. COVID-19 reduced exploration and subjective well-being. Yet, despite the health risks of exploring during the pandemic, the days of highest affective well-being were those when individuals explored the most. However, this was not true for everyone: during the first months of the pandemic, at the height of the uncertainty surrounding the transmissibility and prognosis of a COVID-19 infection, more anxious individuals experienced no affective benefit to leaving home. Taken together, real-world exploration improved well-being regardless of the presence of real-world threat, but anxiety mitigated these benefits. (PsycInfo Database Record (c) 2024 APA, all rights reserved).</p>","PeriodicalId":73914,"journal":{"name":"Journal of psychopathology and clinical science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10896552/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138809751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Posttraumatic symptoms and poor sleep are independent pathways to agency disruptions and dissociation: A longitudinal study with objective sleep assessment. 创伤后症状和睡眠不佳是导致机构混乱和分离的独立途径:通过客观睡眠评估进行的纵向研究。
Journal of psychopathology and clinical science Pub Date : 2024-02-01 Epub Date: 2023-12-18 DOI: 10.1037/abn0000885
Noa Bregman-Hai, Nirit Soffer-Dudek
{"title":"Posttraumatic symptoms and poor sleep are independent pathways to agency disruptions and dissociation: A longitudinal study with objective sleep assessment.","authors":"Noa Bregman-Hai, Nirit Soffer-Dudek","doi":"10.1037/abn0000885","DOIUrl":"10.1037/abn0000885","url":null,"abstract":"<p><p>Dissociation and diminished sense of agency are experiential distortions of disintegration in the perception of self and action. Although one is often implied in the other, they are seldom studied together. Assessing their relationship and shared influences may allow for a more comprehensive and nuanced understanding of dissociative experiences. We aimed to examine their temporal (concurrent or directional) co-occurrence, and to elucidate their etiology, focusing on posttraumatic symptoms (PTS), poor sleep, and their hypothesized joint effect. N = 113 adults oversampled for the existence of trauma exposure history reported PTS and then, for a week, wore an actigraphic sleep monitor, reported subjective sleep quality each morning, and reported state dissociation (depersonalization, derealization, and absorption) and sense of agency four times each day. Data were analyzed using multilevel linear modeling. Higher state dissociation correlated with diminished state sense of agency, but only contemporaneously, not directionally. Both hypothesized etiological factors, namely, PTS (especially complex) and poor sleep (objective and subjective) predicted state dissociation and diminished state sense of agency, but psychological distress seemed to overshadow these main effects. However, robust interactive effects suggested that poor sleep predicted dissociation and disruptions in the sense of agency only among individuals with low PTS. These findings suggest that PTS and poor sleep quality are separate paths to dissociation and impaired sense of agency. (PsycInfo Database Record (c) 2024 APA, all rights reserved).</p>","PeriodicalId":73914,"journal":{"name":"Journal of psychopathology and clinical science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138809544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Daily prediction of inpatient suicide attempts using routinely collected theory-driven data. 利用日常收集的理论数据,对住院病人企图自杀的情况进行日常预测。
Journal of psychopathology and clinical science Pub Date : 2024-02-01 Epub Date: 2023-12-14 DOI: 10.1037/abn0000880
Michael J Kyron, Geoff R Hooke, Craig J Bryan, Glenn Kiekens, Wai Chen, Nikhila Udupa, Thomas Joiner, Andrew C Page
{"title":"Daily prediction of inpatient suicide attempts using routinely collected theory-driven data.","authors":"Michael J Kyron, Geoff R Hooke, Craig J Bryan, Glenn Kiekens, Wai Chen, Nikhila Udupa, Thomas Joiner, Andrew C Page","doi":"10.1037/abn0000880","DOIUrl":"10.1037/abn0000880","url":null,"abstract":"<p><p>We lack knowledge about the short-term predictors of suicide attempts (SAs) among treatment-seeking individuals. The current study evaluated whether (a) interpersonal difficulties, hopelessness, and affective states are associated with an increased risk of SAs on the same and the next day; (b) these daily states are interconnected differently over time among inpatients who attempt suicide compared to those who do not. In total, 110 psychiatric inpatients who attempted suicide during their stay at a psychiatric hospital self-reported their suicidal ideation, negative affect, positive affect, wish to live, interpersonal needs, and hopelessness each day (3,018 daily reports). Multilevel structural equation modeling was used to examine same-day and next-day predictors of SAs. Multilevel temporal network models assessed interconnectedness between daily predictors and were compared to network models from a matched sample of 110 psychiatric inpatients who did not attempt suicide. In multivariate models, increases in perceived burdensomeness were significantly associated with same-day SAs, whereas increased hopelessness was associated with next-day SAs. Network models for patients who attempted suicide indicated that hopelessness and suicidal ideation were central to change, leading to next-day deteriorations in mental health. In subsequent models, feeling calm and relaxed, and feeling fresh and rested were centrally connected to other variables. The centrality of these metrics tended to be higher than in the network models for patients who did not attempt suicide, suggesting differences in the interplay between risk and protective factors. This study suggests routinely monitoring interpersonal factors and hopelessness may help identify increased short-term risk of SAs among psychiatric inpatients. (PsycInfo Database Record (c) 2024 APA, all rights reserved).</p>","PeriodicalId":73914,"journal":{"name":"Journal of psychopathology and clinical science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138809461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Longitudinal dynamics between anxiety and depression in bipolar spectrum disorders. 双相情感障碍中焦虑与抑郁之间的纵向动态关系。
Journal of psychopathology and clinical science Pub Date : 2024-02-01 Epub Date: 2024-01-08 DOI: 10.1037/abn0000890
Hanjoo Kim, Melvin G McInnis, Sarah H Sperry
{"title":"Longitudinal dynamics between anxiety and depression in bipolar spectrum disorders.","authors":"Hanjoo Kim, Melvin G McInnis, Sarah H Sperry","doi":"10.1037/abn0000890","DOIUrl":"10.1037/abn0000890","url":null,"abstract":"<p><p>Anxiety and depression are common among individuals with bipolar spectrum disorders (BSDs), with anxiety being a risk factor for depression and vice versa. While the harmful effects of these symptoms are well recognized, their temporal dynamics have not been fully tested. To address this gap, our study investigated bidirectional relationships between anxiety and depression in individuals with BSDs using data from the Prechter Longitudinal Study of Bipolar Disorder, collected over an average of 11 years. We included 651 participants with various BSD subtypes (BD I, BD II, BD not otherwise specified, and schizoaffective bipolar type), with at least 5 years' data for adequate statistical power in detecting temporal dynamics. Bimonthly measurements of anxiety and depression were analyzed using dynamic structural equation modeling. Beyond assessing autoregressive and cross-lagged effects, this study also investigated whether temporal dynamics differed based on demographic characteristics and the use of psychiatric medication. Our findings revealed that individuals with BSDs experienced significant fluctuations in anxiety and depression over time. In addition, we found significant autoregressive and cross-lagged effects of anxiety and depression. Comparison of the cross-lagged effects demonstrated that anxiety had a greater effect on subsequent depression than vice versa. Age and marital status impacted cross-lagged and autoregressive effects. Specifically, older participants had stronger temporal associations between depression and subsequent anxiety, while widowed participants exhibited a heightened impact of depression on subsequent depression. These results underscore the importance of early identification and integrative interventions aimed at addressing both anxiety and depression to mitigate subsequent symptoms in BSDs. (PsycInfo Database Record (c) 2024 APA, all rights reserved).</p>","PeriodicalId":73914,"journal":{"name":"Journal of psychopathology and clinical science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139378940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Depressive symptoms as a heterogeneous and constantly evolving dynamical system: Idiographic depressive symptom networks of rapid symptom changes among persons with major depressive disorder. 抑郁症状是一个异质的、不断演变的动态系统:重度抑郁症患者症状快速变化的图像抑郁症状网络。
Journal of psychopathology and clinical science Pub Date : 2024-02-01 DOI: 10.1037/abn0000884
Matthew D Nemesure, Amanda C Collins, George D Price, Tess Z Griffin, Arvind Pillai, Subigya Nepal, Michael V Heinz, Damien Lekkas, Andrew T Campbell, Nicholas C Jacobson
{"title":"Depressive symptoms as a heterogeneous and constantly evolving dynamical system: Idiographic depressive symptom networks of rapid symptom changes among persons with major depressive disorder.","authors":"Matthew D Nemesure, Amanda C Collins, George D Price, Tess Z Griffin, Arvind Pillai, Subigya Nepal, Michael V Heinz, Damien Lekkas, Andrew T Campbell, Nicholas C Jacobson","doi":"10.1037/abn0000884","DOIUrl":"10.1037/abn0000884","url":null,"abstract":"<p><p>Major depressive disorder (MDD) is conceptualized by individual symptoms occurring most of the day for at least two weeks. Despite this operationalization, MDD is highly variable with persons showing greater variation within and across days. Moreover, MDD is highly heterogeneous, varying considerably across people in both function and form. Recent efforts have examined MDD heterogeneity byinvestigating how symptoms influence one another over time across individuals in a system; however, these efforts have assumed that symptom dynamics are static and do not dynamically change over time. Nevertheless, it is possible that individual MDD system dynamics change continuously across time. Participants (N = 105) completed ratings of MDD symptoms three times a day for 90 days, and we conducted time varying vector autoregressive models to investigate the idiographic symptom networks. We then illustrated this finding with a case series of five persons with MDD. Supporting prior research, results indicate there is high heterogeneity across persons as individual network composition is unique from person to person. In addition, for most persons, individual symptom networks change dramatically across the 90 days, as evidenced by 86% of individuals experiencing at least one change in their most influential symptom and the median number of shifts being 3 over the 90 days. Additionally, most individuals had at least one symptom that acted as both the most and least influential symptom at any given point over the 90-day period. Our findings offer further insight into short-term symptom dynamics, suggesting that MDD is heterogeneous both across and within persons over time. (PsycInfo Database Record (c) 2024 APA, all rights reserved).</p>","PeriodicalId":73914,"journal":{"name":"Journal of psychopathology and clinical science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11002496/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139565461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Supplemental Material for Longitudinal Dynamics Between Anxiety and Depression in Bipolar Spectrum Disorders 双相情感障碍中焦虑与抑郁之间的纵向动态关系》补充材料
Journal of psychopathology and clinical science Pub Date : 2024-01-04 DOI: 10.1037/abn0000890.supp
{"title":"Supplemental Material for Longitudinal Dynamics Between Anxiety and Depression in Bipolar Spectrum Disorders","authors":"","doi":"10.1037/abn0000890.supp","DOIUrl":"https://doi.org/10.1037/abn0000890.supp","url":null,"abstract":"","PeriodicalId":73914,"journal":{"name":"Journal of psychopathology and clinical science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139385012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Altered attentional processing of facial expression features in severe alcohol use disorder: An eye-tracking study. 严重酒精使用障碍患者面部表情特征的注意加工改变:一项眼动追踪研究。
Journal of psychopathology and clinical science Pub Date : 2024-01-01 Epub Date: 2023-11-13 DOI: 10.1037/abn0000868
Arthur Pabst, Zoé Bollen, Nicolas Masson, Mado Gautier, Christophe Geus, Pierre Maurage
{"title":"Altered attentional processing of facial expression features in severe alcohol use disorder: An eye-tracking study.","authors":"Arthur Pabst, Zoé Bollen, Nicolas Masson, Mado Gautier, Christophe Geus, Pierre Maurage","doi":"10.1037/abn0000868","DOIUrl":"10.1037/abn0000868","url":null,"abstract":"<p><p>Social cognition impairments, and notably emotional facial expression (EFE) recognition difficulties, as well as their functional and clinical correlates, are increasingly documented in severe alcohol use disorder (SAUD). However, insights into their underlying mechanisms are lacking. Here, we tested if SAUD was associated with alterations in the attentional processing of EFEs. In a preregistered study, 40 patients with SAUD and 40 healthy controls (HCs) had to identify the emotional expression conveyed by faces while having their gaze recorded by an eye-tracker. We assessed indices of initial (first fixation locations) and later (number of fixations and dwell-time) attention with reference to regions of interest corresponding to the eyes, mouth, and nose, which carry key information for EFE recognition. We centrally found that patients had less first fixations to key facial features in general, as well as less fixations and dwell time to the eyes specifically, relative to the rest of the face, compared to controls. These effects were invariant across emotional expressions. Additional exploratory analyses revealed that patients with SAUD had a less structured viewing pattern than controls. These results offer novel, direct, evidence that patients with SAUD's socioaffective difficulties already emerge at the facial attentional processing stage, along with precisions regarding the nature and generalizability of the effects. Potential implications for the mechanistic conceptualization and treatment of social cognition difficulties in SAUD are discussed. (PsycInfo Database Record (c) 2023 APA, all rights reserved).</p>","PeriodicalId":73914,"journal":{"name":"Journal of psychopathology and clinical science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92158039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Do emotion regulation difficulties in depression extend to social context? Everyday interpersonal emotion regulation in current and remitted major depressive disorder. 抑郁症的情绪调节困难会延伸到社会环境吗?重度抑郁障碍的日常人际情绪调节。
Journal of psychopathology and clinical science Pub Date : 2024-01-01 Epub Date: 2023-12-07 DOI: 10.1037/abn0000877
Daphne Y Liu, Michael J Strube, Renee J Thompson
{"title":"Do emotion regulation difficulties in depression extend to social context? Everyday interpersonal emotion regulation in current and remitted major depressive disorder.","authors":"Daphne Y Liu, Michael J Strube, Renee J Thompson","doi":"10.1037/abn0000877","DOIUrl":"10.1037/abn0000877","url":null,"abstract":"<p><p>Individuals with major depressive disorder (MDD) have difficulties regulating emotion on their own. As people also use social resources to regulate emotion (i.e., interpersonal emotion regulation [IER]), we examined whether these difficulties extend to IER in current and remitted MDD compared to those with no psychiatric disorders (i.e., controls). Adults with current MDD (<i>n</i> = 48), remitted MDD (<i>n</i> = 80), and controls (<i>n</i> = 87) assessed via diagnostic interviewing completed 2-week experience sampling, reporting on how frequently (IER frequency), from whom (sharing partners), and why (IER goals) they sought IER; how the sharing partners responded (sharing partner's extrinsic IER strategies and warmth); and how their feelings about the problem and the sharing partner changed following IER (IER outcomes). Using multilevel modeling, the current-MDD group did not differ from controls in IER frequency and sharing partners, but the current-MDD group demonstrated a more mixed (albeit generally adaptive) profile of received IER strategies and benefited similarly or more from certain IER strategies than the other two groups, suggesting that IER may be a promising avenue for effective emotion regulation in current MDD. The remitted-MDD group sought IER most frequently and demonstrated the most adaptive profile of received IER strategies, and they and the current-MDD group reported seeking more types of IER goals than controls. People with remitted MDD seem highly motivated to pursue IER support and their pursuit takes place in particularly supportive social contexts. Research is needed to examine mechanisms driving these group differences and how IER predicts the course of MDD. (PsycInfo Database Record (c) 2023 APA, all rights reserved).</p>","PeriodicalId":73914,"journal":{"name":"Journal of psychopathology and clinical science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138500389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neurocognitive risk phenotyping to predict mood symptoms in adolescence. 神经认知风险表型预测青少年情绪症状。
Journal of psychopathology and clinical science Pub Date : 2024-01-01 Epub Date: 2023-12-07 DOI: 10.1037/abn0000866
Roselinde H Kaiser, Amelia D Moser, Chiara Neilson, Jenna Jones, Elena C Peterson, Luke Ruzic, Benjamin M Rosenberg, Christina M Hough, Christina Sandman, Christopher D Schneck, David J Miklowitz
{"title":"Neurocognitive risk phenotyping to predict mood symptoms in adolescence.","authors":"Roselinde H Kaiser, Amelia D Moser, Chiara Neilson, Jenna Jones, Elena C Peterson, Luke Ruzic, Benjamin M Rosenberg, Christina M Hough, Christina Sandman, Christopher D Schneck, David J Miklowitz","doi":"10.1037/abn0000866","DOIUrl":"10.1037/abn0000866","url":null,"abstract":"<p><p>Predicting mood disorders in adolescence is a challenge that motivates research to identify neurocognitive predictors of symptom expression and clinical profiles. This study used machine learning to test whether neurocognitive variables predicted future manic or anhedonic symptoms in two adolescent samples risk-enriched for lifetime mood disorders (Sample 1, <i>n</i> = 73, ages = 13-25, <i>M</i> [<i>SD</i>] = 19.22 [2.49] years, 68% lifetime mood disorder) or familial mood disorders (Sample 2, <i>n</i> = 154, ages = 13-21, <i>M</i> [<i>SD</i>] = 16.46 [1.95] years, 62% first-degree family history of mood disorder). Participants completed cognitive testing and functional magnetic resonance imaging at baseline, for behavioral and neural measures of reward processing and executive functioning. Next, participants completed a daily diary procedure for 8-16 weeks. Penalized mixed-effects models identified neurocognitive predictors of future mood symptoms and stress-reactive changes in mood symptoms. Results included the following. In both samples, adolescents showing ventral corticostriatal reward hyposensitivity and lower reward performance reported more severe stress-reactive anhedonia. Poorer executive functioning behavior was associated with heightened anhedonia overall in Sample 1, but lower stress-reactive anhedonia in both samples. In Sample 1, adolescents showing ventral corticostriatal reward hypersensitivity and poorer executive functioning reported more severe stress-reactive manic symptoms. Clustering analyses identified, and replicated, five neurocognitive subgroups. Adolescents characterized by neural or behavioral reward hyposensitivities together with average-to-poor executive functioning reported unipolar symptom profiles. Adolescents showing neural reward hypersensitivity together with poor behavioral executive functioning reported a bipolar symptom profile (Sample 1 only). Together, neurocognitive phenotypes may hold value for predicting symptom expression and profiles of mood pathology. (PsycInfo Database Record (c) 2023 APA, all rights reserved).</p>","PeriodicalId":73914,"journal":{"name":"Journal of psychopathology and clinical science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10752243/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138500390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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