Journal of infectious disease and therapy最新文献_第5页

Recent advances in phage display technology 噬菌体展示技术的最新进展

Journal of infectious disease and therapy Pub Date : 2019-01-28 DOI: 10.4172/2332-0877-C6-052

pSharad Kumar Yadavp

引用次数: 0

Effect of Hepatitis C Virus on Erythropoiesis among Sudanese Haemodialysis Patients at Ibn-sena Hospital and Alnao Teaching Hospital 丙型肝炎病毒对Ibn-sena医院和Alnao教学医院苏丹血液透析患者红细胞生成的影响

Journal of infectious disease and therapy Pub Date : 2019-01-01 DOI: 10.4172/2332-0877.1000393

Essamaddin Ahmed Abdelhamid Ibrahim

引用次数: 0

Universal vaccine and artificial pandemics by infectious attenuated live vaccine to save people from dangerous new influenza pandemic 通用疫苗和传染性减毒活疫苗的人工大流行，以拯救人们免受危险的新流感大流行

Journal of infectious disease and therapy Pub Date : 2019-01-01 DOI: 10.4172/2332-0877-c2-061

Y. Hayakawa

引用次数: 0

Knowledge, attitudes and practices on schistosomiasis in sub-saharan africa: A systematic review 撒哈拉以南非洲关于血吸虫病的知识、态度和做法:系统回顾

Journal of infectious disease and therapy Pub Date : 2018-12-14 DOI: 10.4172/2332-0877-C3-045

Hlengiwe Sacolo

引用次数: 59

Chronicle of EBOLA epidemics (2017): The return of EBOLA 埃博拉疫情纪事(2017):埃博拉的回归

Journal of infectious disease and therapy Pub Date : 2018-12-14 DOI: 10.4172/2332-0877-C3-043

pEugenie Bergogne Berezinp

引用次数: 0

Systemic Nocardiosis as Unusual Clinical Onset of Late Advanced HIV Infection: A Case Report 系统性无心脏病是晚期HIV感染的罕见临床发病：一例报告

Journal of infectious disease and therapy Pub Date : 2018-10-25 DOI: 10.11648/J.IJIDT.20180303.13

Santoro Carmen Rita, Brindicci Gaetano, M. Michele, Giannelli Anna, I. Giovanni, Fiore Silvia, Pappalettera Antonio, Capodivento Saverio, Cascarano Marina, Quinto Nicola, L. Ruggero, L. Monno

{"title":"Systemic Nocardiosis as Unusual Clinical Onset of Late Advanced HIV Infection: A Case Report","authors":"Santoro Carmen Rita, Brindicci Gaetano, M. Michele, Giannelli Anna, I. Giovanni, Fiore Silvia, Pappalettera Antonio, Capodivento Saverio, Cascarano Marina, Quinto Nicola, L. Ruggero, L. Monno","doi":"10.11648/J.IJIDT.20180303.13","DOIUrl":"https://doi.org/10.11648/J.IJIDT.20180303.13","url":null,"abstract":"The genus Nocardia includes aerobic actinomycetes causing disease in both humans and animals. Nocardiosis is a rare bacterial infection, but the incidence of human disease has increased in the recent years in association with an increasing population of immune-compromised hosts and the improved methods for detection and identification of Nocardia spp. in the clinical laboratory. All those situations of immune-system compromise are conditions associated with increased risk, especially when cell-mediated immunity is involved. The prognosis depends both upon the immediacy of therapy initiation, concomitant disorders and the immune status of the patient. Recently cases of multi-drug resistance nocardiosis and the epidemiology and drug susceptibility of less common Nocardia species have been described. In HIV positive patients pulmonary nocardiosis, the most common clinical presentation, has a low reported prevalence of 0.3%, and it is not considered an AIDS-defining disease. The difficulties in isolation, the non-specific clinical and radiologic presentation, and the widespread use of cotrimoxazole (TMP/SMX) prophylaxis could be responsible for this low prevalence. In this paper, it is described a rare and fatal case of systemic nocardiosis arising with chest pain in a patient with a severe immune deficiency, unaware of his HIV positivity. Systemic nocardiosis is generally caused by N. asteroids and the prognosis is good, but in patients with AIDS, mortality in disseminated forms with central nervous system involvement is more than 50%.","PeriodicalId":73792,"journal":{"name":"Journal of infectious disease and therapy","volume":"3 1","pages":"62"},"PeriodicalIF":0.0,"publicationDate":"2018-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47586717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Treatment of Clostridium Difficile Infection in Community Teaching Hospital: A Retrospective Study 社区教学医院难辨梭菌感染治疗的回顾性研究

Journal of infectious disease and therapy Pub Date : 2018-10-23 DOI: 10.11648/J.IJIDT.20180303.12

Ali Elbeddini

{"title":"Treatment of Clostridium Difficile Infection in Community Teaching Hospital: A Retrospective Study","authors":"Ali Elbeddini","doi":"10.11648/J.IJIDT.20180303.12","DOIUrl":"https://doi.org/10.11648/J.IJIDT.20180303.12","url":null,"abstract":"Clostridium difficile infection (CDI) is responsible for 15 – 25% cases of health-care associated diarrhea. The CDI treatment algorithm used at our hospital is adapted from the Infectious Diseases Society of America 2010 C. difficile guideline. The primary objective of this study was to assess the treatment adherence to our algorithm; this was defined as therapy consisting of the appropriate antibiotic, dose, route, interval and duration indicated based on the disease severity and episode within 24 hours of diagnosis. In addition, our study also described the population and their risk factors for CDI at our hospital. This was a single-centre, retrospective cohort chart review of CDI cases that were diagnosed at admission or during hospitalization from June 1st 2017 to June 30th 2018. Sixty cases were included, of which adherence to our algorithm was 50%. Overall, severe CDI had the highest treatment non-adherence (83%) and the biggest contributing factor was prescribing the wrong antibiotic (72%). In severe CDI, which warrants vancomycin monotherapy, wrong antibiotic consisted of metronidazole monotherapy (55%) or dual therapy with metronidazole and vancomycin (45%). Patients were mostly older, females being treated for an initial episode of mild to moderate CDI. Common risk factors identified were age over 65 years (80%), use of antibiotics (83%) and proton pump inhibitors (PPI) (68%) within the previous three months. The use of a PPI in this study, a modifiable risk factor without a clear indication was 35%. The conclusion was that there is an area for antimicrobial stewardship intervention in CDI treatment at our hospital is prescribing the right antibiotic based on the CDI indication. In severe CDI, an emphasis should be on prescribing vancomycin monotherapy as the drug of choice. PPI use should be reassessed for tapering when appropriate.","PeriodicalId":73792,"journal":{"name":"Journal of infectious disease and therapy","volume":"3 1","pages":"52"},"PeriodicalIF":0.0,"publicationDate":"2018-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45330700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Co-Infection Prevalence of Herpes Simplex Virus Types 1 and 2 with Human Papillomavirus and Associated Risk Factors among Asymptomatic Women in Ghana 加纳无症状妇女中1型和2型单纯疱疹病毒与人乳头瘤病毒共同感染的患病率及相关危险因素

Journal of infectious disease and therapy Pub Date : 2018-10-23 DOI: 10.11648/j.ijidt.20180303.11

Agyemang-Yeboah Francis, Debrah Oksana, D. Timmy, Asmah Harry Richard, Seini Mustapha Mohammed

{"title":"Co-Infection Prevalence of Herpes Simplex Virus Types 1 and 2 with Human Papillomavirus and Associated Risk Factors among Asymptomatic Women in Ghana","authors":"Agyemang-Yeboah Francis, Debrah Oksana, D. Timmy, Asmah Harry Richard, Seini Mustapha Mohammed","doi":"10.11648/j.ijidt.20180303.11","DOIUrl":"https://doi.org/10.11648/j.ijidt.20180303.11","url":null,"abstract":"Herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) are among the most common human viral infections worldwide and associated with increased risk for other sexually transmitted infections, such as HPV. Unfortunately, there is a dearth of population data on the joint epidemiology of HPV-HSV infections in Ghana. In order to determine the prevalence of HSV-1 and HSV-2 co-infection with HPV and associated risk factors, 317 asymptomatic women attending the Cervicare Centers in Ghana were invited to participate in cross-sectional study. Serum HSV-1 and HSV-2 IgG were determined by ELISA method. Genomic DNA from cervical swabs was extracted using QIAamp Mini kit. HPV-DNA detection was carried out by nested multiplex PCR as was described by Sotlar et al., (2004). The mean age of study participants was 40.7 years (SD ± 11.2). Our result showed the prevalence of HSV-1 and HSV-2 infection among HPV positive women as 98.6% and 80.4% respectively. Among unscreened women participating in the study the co-infection of HSV-1/HPV and HSV-2/HPV was 42.9% and 35.0%, respectively. Age of coitache was associated with sero-prevalence of HSV-1 (p=0.010), HPV infection (p=0.016), and with co-infection HPV and HSV-1 (p=0.025), HPV and HSV-2 (p=0.011) and weakly with single HSV-2 infection (p=0.054). In conclusion, the high prevalence of co-infection was due to the endemicity and inadequate intervention in the study population. A woman’s age of sexual debut was a strong risk factor for co-infection of HPV and HSV-1 or HSV-2. The outcome of this novel observation stresses the urgent need to develop appropriate interventional strategies to manage and cancel patients presenting with asymptomatic genital herpes.","PeriodicalId":73792,"journal":{"name":"Journal of infectious disease and therapy","volume":"3 1","pages":"45"},"PeriodicalIF":0.0,"publicationDate":"2018-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46370887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Serodiagnosis of Hepatitis B Virus Infection among Jessu Community of Gombe State, Nigeria 尼日利亚贡贝州杰苏社区乙型肝炎病毒感染的血清学诊断

Journal of infectious disease and therapy Pub Date : 2018-09-17 DOI: 10.11648/J.IJIDT.20180302.14

Z. Sheyin, Frama Ishaku, E. U. Cosmas, S. John, B. E. Isa

{"title":"Serodiagnosis of Hepatitis B Virus Infection among Jessu Community of Gombe State, Nigeria","authors":"Z. Sheyin, Frama Ishaku, E. U. Cosmas, S. John, B. E. Isa","doi":"10.11648/J.IJIDT.20180302.14","DOIUrl":"https://doi.org/10.11648/J.IJIDT.20180302.14","url":null,"abstract":"Hepatitis B virus causes disease of the liver and is a global health problem that leads to liver cirrhosis and hepatocellular carcinoma. Despite the dangers posed by this silent and deadly disease, there is little or no documented work on Hepatitis B infections in Jessu community, Gombe State, North East Nigeria. This study was undertaken to determine the sero-prevalence of Hepatitis B Virus infection and possible risk factors associated with the transmission of HBV. Blood samples (3ml) were collected from 196 eligible consented subjects and the serum samples were tested for the presence of HBsAg using On Site HBsAg Rapid Test Kit manufactured by CTK Biotech, USA. The OnSite HBV 5-Parameter Rapid Test also manufactured by CTK Biotech, USA was used to confirm those that were positive. Of the 196 eligible subjects examined, 5.6% were confirmed positive for HBsAg, 8.6% were males and 2.9% were females. Age distribution of HBsAg among the population shows the highest seroprevalence of 8.9% HBsAg in ages 16-30 years, followed by 4.5% in ages 31-45 years while ages 0-15 years had 3.5% seroprevalence. Participants who share sharp objects recorded the highest prevalence of 6.3% HCV infection followed by blood transfusion with 5.9% prevalence and those with multiple sex partners had the least prevalence of 1.8% HCV infection. The seroprevalence of 5.6% HBV in this study indicated the presence of HBV in Jessu Community in Gombe State, North East Nigeria.","PeriodicalId":73792,"journal":{"name":"Journal of infectious disease and therapy","volume":"3 1","pages":"40"},"PeriodicalIF":0.0,"publicationDate":"2018-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47928854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Urinary Tract Infections in Patients Admitted to the Nephrology Department 肾内科住院患者的尿路感染

Journal of infectious disease and therapy Pub Date : 2018-08-01 DOI: 10.11648/j.ijidt.20180302.13

Mouayche Ikhlas, H. Hana, Hiddou Abdesalam, El Assas Hajar, F. Wafaa, L. Inass, Soraa Nabila

{"title":"Urinary Tract Infections in Patients Admitted to the Nephrology Department","authors":"Mouayche Ikhlas, H. Hana, Hiddou Abdesalam, El Assas Hajar, F. Wafaa, L. Inass, Soraa Nabila","doi":"10.11648/j.ijidt.20180302.13","DOIUrl":"https://doi.org/10.11648/j.ijidt.20180302.13","url":null,"abstract":"Urinary infections (UI) remain among the most frequent problems faced by the clinician and occupy a prominent place in nephrological pathology due to their frequency and severity. The aim of this work is to study the aspect of UI in the nephrology service. Materials and methods: This is a prospective study over a periodof 5 months (July 2016 – December 2016). Results: 115 patients had benefited from cytobacterioligical urine exam. The prevalence of UI was 31%. The mean age of patients was 38 years with a female predominance. Renal failure was found in 33% of patients followedby nephrotic syndrome (25%) and kidney transplant (11%). Chronic renal insufficiency was foundin25% of patients and 23% receivedan Endoxanbolus. The mostincri minatedspecies were Enterobacteriae (81%) with the predominance of E. coli (44%) followed by Klebsiella pneumoniae (31%) Enterobacter cloacae (3%) resistance to C3G by production of Betalactamases with extended spectrum was found in 24% of Enterobacteriaceae. Resistance to amoxicillin-clavulanic acidwas 72%, fluoroquinolones (34%) and gentamicin (14%). Thefirst-lineantibioticwas Ciprofloxacinin (62%) and a third generation cephalosporin in 28% of cases. Conclusion: Area soned use of antibiotic sisnecessaryin order to prevent the extension of bacterial resistance.","PeriodicalId":73792,"journal":{"name":"Journal of infectious disease and therapy","volume":"3 1","pages":"34"},"PeriodicalIF":0.0,"publicationDate":"2018-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49293995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1