尼日利亚贡贝州杰苏社区乙型肝炎病毒感染的血清学诊断

Z. Sheyin, Frama Ishaku, E. U. Cosmas, S. John, B. E. Isa
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引用次数: 0

摘要

乙型肝炎病毒引起肝脏疾病,是一个全球性的健康问题,可导致肝硬化和肝细胞癌。尽管这种无声而致命的疾病造成了危险,但在尼日利亚东北部贡贝州Jessu社区,很少或没有记录在案的乙型肝炎感染工作。本研究旨在确定乙型肝炎病毒感染的血清患病率以及与HBV传播相关的可能危险因素。从196名符合条件的同意受试者中采集血液样本(3ml),使用美国CTK Biotech公司生产的On Site HBsAg快速检测试剂盒检测血清样本是否存在HBsAg。同样由美国CTK生物技术公司生产的现场HBV 5参数快速检测仪用于确认阳性。在196名符合条件的受试者中,5.6%的人HBsAg阳性,其中8.6%为男性,2.9%为女性。人群中HBsAg的年龄分布显示,16-30岁人群血清阳性率最高,为8.9%,31-45岁人群次之,为4.5%,0-15岁人群血清阳性率为3.5%。共用尖锐物品的参与者HCV感染率最高,为6.3%,其次是输血,为5.9%,而有多个性伴侣的参与者HCV感染率最低,为1.8%。本研究中5.6%的HBV血清阳性率表明在尼日利亚东北部贡贝州Jessu社区存在HBV。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Serodiagnosis of Hepatitis B Virus Infection among Jessu Community of Gombe State, Nigeria
Hepatitis B virus causes disease of the liver and is a global health problem that leads to liver cirrhosis and hepatocellular carcinoma. Despite the dangers posed by this silent and deadly disease, there is little or no documented work on Hepatitis B infections in Jessu community, Gombe State, North East Nigeria. This study was undertaken to determine the sero-prevalence of Hepatitis B Virus infection and possible risk factors associated with the transmission of HBV. Blood samples (3ml) were collected from 196 eligible consented subjects and the serum samples were tested for the presence of HBsAg using On Site HBsAg Rapid Test Kit manufactured by CTK Biotech, USA. The OnSite HBV 5-Parameter Rapid Test also manufactured by CTK Biotech, USA was used to confirm those that were positive. Of the 196 eligible subjects examined, 5.6% were confirmed positive for HBsAg, 8.6% were males and 2.9% were females. Age distribution of HBsAg among the population shows the highest seroprevalence of 8.9% HBsAg in ages 16-30 years, followed by 4.5% in ages 31-45 years while ages 0-15 years had 3.5% seroprevalence. Participants who share sharp objects recorded the highest prevalence of 6.3% HCV infection followed by blood transfusion with 5.9% prevalence and those with multiple sex partners had the least prevalence of 1.8% HCV infection. The seroprevalence of 5.6% HBV in this study indicated the presence of HBV in Jessu Community in Gombe State, North East Nigeria.
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