Dong Hyuck Kim, Yun-A Kim, Tae Hyun Ha, Sang Gyu Kwak
{"title":"Opioid-Sparing Effect of Celiac Plexus Neurolysis in Palliative Care Patients with Upper Abdominal Cancer: A Single-Center Retrospective Case Series of Thirteen Patients.","authors":"Dong Hyuck Kim, Yun-A Kim, Tae Hyun Ha, Sang Gyu Kwak","doi":"10.14475/jhpc.2026.29.2.54","DOIUrl":"10.14475/jhpc.2026.29.2.54","url":null,"abstract":"<p><strong>Purpose: </strong>Whether celiac plexus neurolysis (CPN) retains opioid-sparing efficacy in palliative care patients receiving modern extended-release opioids remains uncertain after a recent randomized trial that reported no benefit. We describe fluoroscopy-guided CPN in such patients.</p><p><strong>Methods: </strong>Thirteen consecutive palliative care patients with unresectable or metastatic upper abdominal cancer (seven pancreatic, five hepatobiliary, one gastric) on strong opioid therapy underwent posterior fluoroscopy-guided CPN with absolute ethanol after a diagnostic lidocaine block. Daily oral morphine equivalent (OME) and Numeric Rating Scale (NRS) pain scores were recorded at baseline and 1, 2, and 4 weeks. Pain response was defined a priori as ≥30% NRS reduction.</p><p><strong>Results: </strong>Median age was 67 years, baseline median OME 86.5 mg/day (range, 15~215), and median NRS 6. Median OME decreased to 72, 60, and 57.5 mg/day at 1, 2, and 4 weeks (median reductions 46.5%, 26.7%, 43.5%; all P≤0.002), and median NRS improved to 3, 4, and 4 (all P≤0.001). A pain response was achieved in 8/13 (61.5%) at 1 week, 7/13 (53.8%) at 2 weeks, and 5/12 (41.7%) at 4 weeks. Opioid-related adverse events declined numerically (nausea, 7/13→3/12; constipation, 4→2; somnolence, 2→0; all McNemar P>0.10). No procedural complication occurred (0/13).</p><p><strong>Conclusion: </strong>CPN was followed by reduction in opioid use and pain scores, with resolution of opioid-related symptoms and no complications. Although limited by the small sample size, these findings suggest a potential role for CPN in palliative care patients receiving extended-release opioids and warrant prospective investigation.</p>","PeriodicalId":73780,"journal":{"name":"Journal of hospice and palliative care","volume":"29 2","pages":"54-60"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13246314/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148221221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ye Sul Jeung, Hak Jun Kim, Jiwon Yu, Jeong-Han Kim, Jin-Ah Sim, Shin Hye Yoo
{"title":"Comparison of Broad-Spectrum Antibiotic Use According to Hospice Utilization Among Patients with Cancer at the End of Life in South Korea: A Nationwide Analysis.","authors":"Ye Sul Jeung, Hak Jun Kim, Jiwon Yu, Jeong-Han Kim, Jin-Ah Sim, Shin Hye Yoo","doi":"10.14475/jhpc.2026.29.2.41","DOIUrl":"10.14475/jhpc.2026.29.2.41","url":null,"abstract":"<p><strong>Purpose: </strong>We aimed to compare broad-spectrum antibiotic use between hospice and non-hospice patients with cancer at the end of life using nationwide data from Korea.</p><p><strong>Methods: </strong>In this retrospective cohort study, we analyzed the Korean National Health Insurance Service data of adult patients with cancer who died between 2018 and 2021. Hospice users were defined as patients who received inpatient, home-based, or consultation-based hospice care before death. We applied propensity score matching (12) to balance the baseline characteristics of the hospice and non-hospice groups. Broad-spectrum antibiotic use, including anti-pseudomonal penicillins, anti-pseudomonal cephalosporins, carbapenems, and glycopeptides, was assessed during the last 3 months of life using prescription proportions and days of therapy per 1,000 patient-days.</p><p><strong>Results: </strong>After matching, 38,102 hospice and 75,736 non-hospice users were analyzed. During the last 3 months of life, 74.6% of hospice and 79.0% of non-hospice users received at least one broad-spectrum antibiotic (P<0.001). The proportion of patients receiving broad-spectrum antibiotics was generally lower among hospice users across all time intervals (P<0.001), and the number of days of therapy was also lower, with the largest differences observed during the final week and last 3 days of life. Subgroup analyses showed the highest antibiotic exposure among patients with hematologic and pancreatobiliary cancers, particularly in the non-hospice group.</p><p><strong>Conclusion: </strong>Hospice involvement was associated with lower use and reduced exposure to broad-spectrum antibiotics among patients with cancer near the end of life. These findings support the alignment of end-of-life treatment decisions with the comfort-oriented goals of hospice care.</p>","PeriodicalId":73780,"journal":{"name":"Journal of hospice and palliative care","volume":"29 2","pages":"41-50"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13246315/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148221229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Transfusion in Hospice-Palliative Care.","authors":"Changho An","doi":"10.14475/jhpc.2026.29.2.51","DOIUrl":"10.14475/jhpc.2026.29.2.51","url":null,"abstract":"<p><p>Transfusion in hospice and palliative care remains a complex issue as it is viewed as either a futile life-prolonging treatment or a legitimate intervention for symptom relief. These differing views result in inconsistent clinical practices. Anemia is common in terminally ill patients and is associated with fatigue, dyspnea, dizziness, palpitations, cognitive decline, and an impaired quality of life. Although red blood cell transfusion may provide short-term symptomatic improvement in selected patients, its benefits are often transient; repeated transfusions may be necessary, and its effect on patient survival is limited. Additionally, access to transfusion varies considerably across care settings, with relatively greater availability in tertiary hospitals and substantial barriers in many inpatient hospice units and home hospice services due to institutional and logistical constraints. This brief communication described an 88-year-old man with myelodysplastic syndrome whose transfusion-dependent fatigue substantially influenced decisions regarding hospice care. As a nearby hospice facility did not offer transfusion, the patient and family continued long-distance hospital visits to maintain symptom control. Hospice admission was delayed until his condition rapidly worsened. This case demonstrated that transfusion in patients with terminal illness may carry clinical significance not only in relation to survival, but also in providing symptom relief and in shaping patient and family preferences. Therefore, transfusion in hospice and palliative care should be considered case-by-case within an individualized, goal-concordant framework based on symptom burden, prognosis, patient values, treatment burden, institutional feasibility, and ethical principles, supported by shared decision-making and careful reassessment.</p>","PeriodicalId":73780,"journal":{"name":"Journal of hospice and palliative care","volume":"29 2","pages":"51-53"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13246313/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148221171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Factors Influencing End-of-Life Care Performance Among Community Care Workers Prior to the Implementation of the Integrated Care Support Act: Focusing on Home Care Aides.","authors":"Jae Eun Yu, Ju Young Park, Young Gil Jeong","doi":"10.14475/jhpc.2026.29.1.10","DOIUrl":"10.14475/jhpc.2026.29.1.10","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to identify the factors influencing end-of-life care performance among community-based care workers prior to the implementation of the Integrated Care Support Act in South Korea.</p><p><strong>Methods: </strong>A cross-sectional survey was conducted among 153 community care workers who provided home-based services. Data were collected using structured questionnaires that assessed perceptions of a good death, attitudes toward end-of-life care, end-of-life care stress, and end-of-life care performance. Data analysis included descriptive statistics, independent t tests, Pearson correlation coefficients, and hierarchical multiple regression using SPSS version 29.0.</p><p><strong>Results: </strong>End-of-life care performance demonstrated a significant positive correlation with end-of-life care stress (r=0.43, P<0.001). Hierarchical regression analysis identified end-of-life care stress (β=0.32, P< 0.001), gender (female; β=-0.20, P=0.01), and intention to participate in end-of-life care education (β=-0.20, P=0.01) as significant predictors. The final model explained 25% of the variance in end-of-life care performance.</p><p><strong>Conclusion: </strong>End-of-life care stress was the strongest predictor of performance among community-based care workers, along with gender and intention to participate in end-of-life care education. These findings suggest that, when appropriately managed and supported, end-of-life care stress may function as a motivating factor rather than solely a burden. Therefore, structured education and emotional support interventions-such as debriefing and peer-based supervision-are recommended. Additionally, the implementation of the Integrated Care Support Act should be accompanied by institutional systems that facilitate effective end-of-life care practices.</p>","PeriodicalId":73780,"journal":{"name":"Journal of hospice and palliative care","volume":"29 1","pages":"10-20"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12994747/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147482763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impact of Junior Physicians' Resignation on Palliative Sedation Practices: A Retrospective Single-Center Study in South Korea.","authors":"Moonki Hong, Si Won Lee, Minkyu Jung","doi":"10.14475/jhpc.2026.29.1.21","DOIUrl":"10.14475/jhpc.2026.29.1.21","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to evaluate changes in the proportion of patients receiving palliative sedation (PS) before and after the mass resignation of junior physicians in South Korea.</p><p><strong>Methods: </strong>This single-center retrospective chart review included patients who died between February 19, 2023 and August 18, 2024. We retrospectively identified patients who were prescribed sedatives such as midazolam outside the intensive care unit on the day of death and classified them as having received PS. Data were extracted from electronic medical records. Categorical variables were compared using the chi-square test, while continuous variables were compared using the Student's t-test.</p><p><strong>Results: </strong>In the year before resignation, 78 of the 745 deceased patients (10.5%) received PS; whereas in the subsequent six months, 24 of the 237 patients (10.1%) received PS. No statistically significant difference was observed in the proportion of patients receiving PS between the two periods.</p><p><strong>Conclusion: </strong>The proportion of patients receiving PS did not show a significant difference, despite the disruption caused by the mass resignation of junior physicians.</p>","PeriodicalId":73780,"journal":{"name":"Journal of hospice and palliative care","volume":"29 1","pages":"21-25"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12994746/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147482757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chung-Woo Lee, Youn Seon Choi, Dae-Kyun Kim, So-Hi Kwon, Won-Chul Kim, Na-Young Kim-Yoon, Hye Yoon Park, Jaesok Kim, Ji-Kyoung Kim
{"title":"Experiences of End-of-Life Care Among Medical Staff in Acute Care Hospitals: A Qualitative Study.","authors":"Chung-Woo Lee, Youn Seon Choi, Dae-Kyun Kim, So-Hi Kwon, Won-Chul Kim, Na-Young Kim-Yoon, Hye Yoon Park, Jaesok Kim, Ji-Kyoung Kim","doi":"10.14475/jhpc.2026.29.1.1","DOIUrl":"10.14475/jhpc.2026.29.1.1","url":null,"abstract":"<p><strong>Purpose: </strong>This study explored the experiences of physicians and nurses providing end-of-life care in Korean acute care hospitals. It aimed to identify the challenges faced in caring for dying patients and to suggest strategies for improving hospital-based end-of-life care.</p><p><strong>Methods: </strong>A qualitative exploratory design was employed using focus group interviews. Eleven healthcare professionals (five physicians and six nurses) working in tertiary or general hospitals participated in the study between July and August 2018. The interviews were conducted using a semi-structured guide covering seven thematic areas. All sessions were audio-recorded, transcribed verbatim, and analyzed thematically following Braun and Clarke's framework.</p><p><strong>Results: </strong>Six major themes emerged (1) communication with patients and families, (2) physical care for dying patients, (3) psychological and spiritual support, (4) hospital environment and system constraints, (5) moral distress and emotional burden on healthcare providers, and (6) suggestions for improvement. The participants described difficulties in open communication, limited resources for comfort care, emotional strain from invasive treatment at the end of life, and the absence of standardized institutional protocols. They emphasized the need for structured communication training, multidisciplinary collaboration, and integration of palliative care principles into acute care practice.</p><p><strong>Conclusion: </strong>Physicians and nurses play a pivotal yet emotionally demanding role in providing end-of-life care in acute hospitals. Institutional reforms, including education, protocol development, and supportive environments, are essential to ensuring dignified, patient-centered care and sustain healthcare providers in their professional roles.</p>","PeriodicalId":73780,"journal":{"name":"Journal of hospice and palliative care","volume":"29 1","pages":"1"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12994748/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147482715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Psychological Resilience and Quality of Life in Family Caregivers of Patients with Terminal Cancer Across Levels of Spiritual Well-Being: A Multicenter Cross-Sectional Survey.","authors":"In Cheol Hwang, Myung-Nam Lee, Hong Yup Ahn","doi":"10.14475/jhpc.2025.28.4.184","DOIUrl":"10.14475/jhpc.2025.28.4.184","url":null,"abstract":"<p><strong>Purpose: </strong>This study investigated the role of spiritual well-being (SWB) in mediating or moderating the association between psychological resilience and quality of life (QoL) among family caregivers (FCs) of patients with terminal cancer.</p><p><strong>Methods: </strong>This cross-sectional study included FCs from nine hospice care units in South Korea between September 2021 and May 2023. Psychological resilience was assessed using the Connor-Davidson Resilience Scale (SWB) and the FACIT-Sp-12, and QoL was assessed using the Caregiver QoL Index-Cancer (CQOLC-K). A multivariate regression analysis was also performed.</p><p><strong>Results: </strong>The study included 164 FCs with a mean age of 53.6 years; Most were female (76.2%) and spouses (40.2%). Resilience showed a significant positive association with QoL and was related to lower burdensomeness and higher positive adaptation. Subgroup analyses based on the SWB levels revealed that the association between resilience and burdensomeness was significant only among FCs with low SWB, whereas the association with positive adaptation was significant among those with high SWB.</p><p><strong>Conclusion: </strong>Among the FCs of patients with terminal cancer, resilience reflects QoL, in which SWB may play an important role.</p>","PeriodicalId":73780,"journal":{"name":"Journal of hospice and palliative care","volume":"28 4","pages":"184-189"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12683175/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145716986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Nurses' Perspectives on Knowledge and Attitudes Toward Palliative Care in Jharkhand, India.","authors":"Kusum Kumari, C Vasantha Kalyani, Rishabh Jaju, Amiy Arnav, Kahkasha, Jharna Kumar, Sharanbasappa, Bhagyasri Ray, Seema Kunikullaya Rao","doi":"10.14475/jhpc.2025.28.4.152","DOIUrl":"10.14475/jhpc.2025.28.4.152","url":null,"abstract":"<p><strong>Purpose: </strong>Palliative care is an essential aspect of healthcare, particularly for patients with life-limiting illnesses. Nurses play a crucial role in the provision of palliative care. In regions such as Jharkhand, India, where palliative care services are still developing, it is important to assess the level of preparedness among healthcare professionals, particularly nurses. This study aimed to assess nurses' knowledge of and attitudes nurses in Jharkhand toward palliative care.</p><p><strong>Methods: </strong>A cross-sectional descriptive study was conducted among 200 registered nurses working in government and private healthcare facilities in Jharkhand were included in this study. A structured questionnaire comprising demographic questions, 20 knowledge-based multiple-choice questions, and a 30-item attitude scale was used for data collection.</p><p><strong>Results: </strong>Most nurses (57%) demonstrated moderate knowledge of palliative care, and 79% of the participants showed a positive attitude toward palliative care. Nurses with palliative care training and more than five years of experience were significantly more likely to have adequate knowledge (odds ratio [OR]=4.52, P=0.001; OR=3.85, P=0.002). Nurses of Jharkhand had more positive attitudes toward palliative care when they had more education (OR=4.82, P=0.040) and worked in government healthcare facilities (OR=2.63, P=0.007).</p><p><strong>Conclusion: </strong>This study emphasizes the need for structured education and training programs, especially in government facilities, to improve nurses' knowledge and prepare them to provide comprehensive palliative care. Enhancing nursing education and offering regular professional development opportunities are essential to improve the overall quality of palliative care delivery in the region.</p>","PeriodicalId":73780,"journal":{"name":"Journal of hospice and palliative care","volume":"28 4","pages":"152-159"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12683179/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145716974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"End-of-life Care Experience of Home-Based Hospice Nurses.","authors":"Misung Bang, Hyeongnam Yeo, Insook Kim","doi":"10.14475/jhpc.2025.28.4.169","DOIUrl":"10.14475/jhpc.2025.28.4.169","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to explore home-based hospice nurses' end-of-life care experiences and elucidate the nature and meaning of end-of-life care. This study aimed to enhance the understanding of nurses' role identity and provide basic data to improve the quality of home-based hospice care.</p><p><strong>Methods: </strong>The collected data were analyzed using Giorgi's phenomenological. The participants were 11 nurses working at a home-based hospice facility in Seoul and the surrounding metropolitan area selected through purposive sampling. Data were collected from August to November 2024 through semi-structured, in-depth individual interviews, each lasting an average of 64 minutes. Interviews were recorded and transcribed with the participants' consent, resulting in 267 pages of data. The collected data were analyzed using Giorgi's phenomenological method.</p><p><strong>Results: </strong>The analysis revealed four thematic categories, \"Practicing emotional care,\" \"Burden and burnout of professional life,\" \"Rediscovering the meaning of existence\" and \"Awareness of sustainable care systems.\" Home-based hospice nurses supported patients and their families in accepting death and forming emotional bonds. They also experienced both burnout and fulfillment during the repetitive process of providing end-of-life care. Furthermore, they achieved personal and professional growth through reflection on life and death but recognized structural limitations such as a lack of staff and inadequate institutional support.</p><p><strong>Conclusion: </strong>This study demonstrates that end-of-life care provided by home-based hospice nurses extends beyond simple physical care to include emotional and spiritual support, demonstrating the need for institutionalization, strengthening the educational foundation, and establishing a practical support system.</p>","PeriodicalId":73780,"journal":{"name":"Journal of hospice and palliative care","volume":"28 4","pages":"169-179"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12683181/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145717018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Palliative Care Integration in Oncology: A Review and Update.","authors":"Claire Wang, Thomas W LeBlanc","doi":"10.14475/jhpc.2025.28.4.121","DOIUrl":"10.14475/jhpc.2025.28.4.121","url":null,"abstract":"<p><p>Palliative care (PC) is increasingly recognized as an essential component of high-quality cancer care, with evidence from randomized trials and meta-analyses demonstrating that it improves quality of life, mood, and goal-concordant end-of-life care. Despite these benefits, PC integration has been inconsistent, with many patients still receiving PC later in their disease course. Current models of integration include outpatient co-located PC clinics, inpatient consultation services, community- and home-based programs, and more recent innovations, such as telehealth and stepped approaches. These models have shown clear benefits; however, they are frequently organized by care settings rather than patient-specific needs, resulting in both underuse and inefficiency. Emerging evidence has begun to clarify the mechanisms through which PC provides patient benefits. Symptom control, coping support, longitudinal communication, and existential or spiritual interventions are among the active ingredients that are most consistently associated with improvements in patient outcomes. Recognition of these mechanistic drivers highlights the potential for precision PC, in which care is tailored to the unique drivers of each patient's needs. Implementation of precision PC requires embedding validated patient-reported outcomes and structured referral algorithms into oncology workflows, enabling real-time triage of targeted interventions. Interoperable technology, workforce expansion through the training of non-specialists, and policy reforms that support scalable delivery models, such as telehealth and nurse-led programs, will be essential for closing gaps in terms of access and equity. Precision PC offers a pragmatic framework for aligning limited resources with the diverse and evolving needs of patients with cancer, ensuring timely, individualized, and sustainable integration into modern oncology.</p>","PeriodicalId":73780,"journal":{"name":"Journal of hospice and palliative care","volume":"28 4","pages":"121-130"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12683178/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145717034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}