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Tyrosinase-Inhibitory Activity in Some Species of the Lichen Family Graphidaceae 部分地衣科植物酪氨酸酶抑制活性研究
Journal of herbal pharmacotherapy Pub Date : 2006-01-01 DOI: 10.1080/J157v06n01_06
B. Behera, B. Adawadkar, U. Makhija
{"title":"Tyrosinase-Inhibitory Activity in Some Species of the Lichen Family Graphidaceae","authors":"B. Behera, B. Adawadkar, U. Makhija","doi":"10.1080/J157v06n01_06","DOIUrl":"https://doi.org/10.1080/J157v06n01_06","url":null,"abstract":"Twenty-five species of the lichen family Graphidaceae have been investigated for tyrosinaseinhibitory activity. Tyrosinase-inhibiting material was extracted with solvents methanol, acetone, ethanol, dimethyl sulphoxide in water, and with water only. Methanol has been found to be suitable for extracting adequate amounts of tyrosinaseinhibiting component from the natural thallus. The lichen species such as Graphina glaucorufa, Graphina multistriata, Graphina salacinilabiata, Graphis assamensis, Graphis nakanishiana, and Phaeographopsis indica, have shown inhibition of tyrosinase over a range of 30-78%. Half-inhibiting concentration (IC50, J.g/ml) has been found to be much lower than the standard tyrosinase inhibitors and thus can compete with other commercially available tyrosinase inhibitors. The extracts of these species have been found to be stable at 4°C.","PeriodicalId":73776,"journal":{"name":"Journal of herbal pharmacotherapy","volume":"6 1","pages":"55 - 69"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/J157v06n01_06","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"60734262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 14
Tyrosinase-inhibitory activity in some species of the lichen family Graphidaceae. 部分地衣科植物酪氨酸酶抑制活性研究。
Journal of herbal pharmacotherapy Pub Date : 2006-01-01
Bhaskar C Behera, Bharathi Adawadkar, Urmila Makhija
{"title":"Tyrosinase-inhibitory activity in some species of the lichen family Graphidaceae.","authors":"Bhaskar C Behera,&nbsp;Bharathi Adawadkar,&nbsp;Urmila Makhija","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Twenty-five species of the lichen family Graphidaceae have been investigated for tyrosinase-inhibitory activity. Tyrosinase-inhibiting material was extracted with solvents methanol, acetone, ethanol, dimethyl sulphoxide in water, and with water only. Methanol has been found to be suitable for extracting adequate amounts of tyrosinase-inhibiting component from the natural thallus. The lichen species such as Graphina glaucorufa, Graphina multistriata, Graphina salacinilabiata, Graphis assamensis, Graphis nakanishiana, and Phaeographopsis indica, have shown inhibition of tyrosinase over a range of 30-78%. Half-inhibiting concentration (IC(50), microg/ml) has been found to be much lower than the standard tyrosinase inhibitors and thus can compete with other commercially available tyrosinase inhibitors. The extracts of these species have been found to be stable at 4 degrees C.</p>","PeriodicalId":73776,"journal":{"name":"Journal of herbal pharmacotherapy","volume":"6 1","pages":"55-69"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26413783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antisecretory and antiulcer activity of Asparagus racemosus Willd. against indomethacin plus phyloric ligation-induced gastric ulcer in rats. 总状芦笋的抗分泌和抗溃疡活性。吲哚美辛联合幽门结扎诱导大鼠胃溃疡的研究。
Journal of herbal pharmacotherapy Pub Date : 2006-01-01
Maheep Bhatnagar, S S Sisodia
{"title":"Antisecretory and antiulcer activity of Asparagus racemosus Willd. against indomethacin plus phyloric ligation-induced gastric ulcer in rats.","authors":"Maheep Bhatnagar,&nbsp;S S Sisodia","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>To study the antisecretory and antiulcer activity of Asparagus racemosus Willd. (methanolic extract) and its action against indomethacin (a non-steroidal anti-inflammatory drug) plus pyloric ligation (PL)-induced gastric ulcers in rats.</p><p><strong>Method: </strong>Indomethacin plus PL-induced gastric ulceration model was used in the study.</p><p><strong>Results: </strong>Treatment with Asparagus racemosus (Shatavari) crude extract (100 mg/kg/day orally) for fifteen days significantly reduced ulcer index when compared with control group. The reduction in gastric lesions was comparable to a standard antiulcer drug Ranitidine (30 mg/kg/ day orally). Crude extract also significantly reduced volume of gastric secretion, free acidity and total acidity. A significant increase in total carbohydrate (TC) and TC/total protein (TP) ratio of gastric juice was also observed. No significant change in the total protein was noted.</p><p><strong>Conclusion: </strong>Asparagus racemosus was found to be an effective antiulcerogenic agent, whose activity can well be compared with that of ranitidine hydrochloride. The results of this study suggest that Asparagus racemosus causes an inhibitory effect on release of gastric hydrochloric acid and protects gastric mucosal damage.</p>","PeriodicalId":73776,"journal":{"name":"Journal of herbal pharmacotherapy","volume":"6 1","pages":"13-20"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26413779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Inhibitory effects of peony root extract on the large conductance calcium-activated potassium current essential in production of bursting activity. 牡丹根提取物对爆裂活性产生所必需的大电导钙活化钾电流的抑制作用。
Journal of herbal pharmacotherapy Pub Date : 2006-01-01
Eiichi Sugaya, Wen Jin, Aiko Sugaya, Katsuyoshi Sunaga, Tadashi Tsuda
{"title":"Inhibitory effects of peony root extract on the large conductance calcium-activated potassium current essential in production of bursting activity.","authors":"Eiichi Sugaya,&nbsp;Wen Jin,&nbsp;Aiko Sugaya,&nbsp;Katsuyoshi Sunaga,&nbsp;Tadashi Tsuda","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>To elucidate the mechanism of inhibitory action of peony root extract on pentylenetetrazol-induced bursting activity, effects of peony root extract on the iberiotoxin-sensitive large conductance calcium-activated potassium (BKCa) current that plays an essential role in the production of bursting activity were investigated. Peony root extract showed a clear inhibitory effect on the iberiotoxin-sensitive calcium-activated potassium current. Peony root extract also showed clear inhibitory effects on spontaneous bursting activity and BKCa current in the cerebral cortical neurons of the EL mouse, a hereditary epilepsy animal model. These results together with our previous studies, including the protective effect against neuron damage, indicate that peony root extract is a promising herbal drug for inhibition of convulsions.</p>","PeriodicalId":73776,"journal":{"name":"Journal of herbal pharmacotherapy","volume":"6 2","pages":"65-77"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26513091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Protective Effect of Indigofera aspalathoides Against CCl4-Induced Hepatic Damage in Rats 蓝草对ccl4致大鼠肝损伤的保护作用
Journal of herbal pharmacotherapy Pub Date : 2006-01-01 DOI: 10.1080/J157v06n01_05
B. Rajkapoor, B. Jayakar, S. Kavimani, N. Murugesh
{"title":"Protective Effect of Indigofera aspalathoides Against CCl4-Induced Hepatic Damage in Rats","authors":"B. Rajkapoor, B. Jayakar, S. Kavimani, N. Murugesh","doi":"10.1080/J157v06n01_05","DOIUrl":"https://doi.org/10.1080/J157v06n01_05","url":null,"abstract":"The alcoholic extract of stem of Indigofera aspalathoides was evaluated for its antihepatotoxic activity against CCl4-induced hepatic damage in rats. The activity was evaluated by using biochemical parameters, such as serum glutamate pyruvate transaminase (SGPT), serum glutamate oxaloacetate transaminase (SGOT), alkaline phosphatase (ALP), total bilirubin and gama glutamate transpeptidase (GGTP). The histopathological changes of liver sample were compared with respective control. The extract showed remarkable hepatoprotective effect.","PeriodicalId":73776,"journal":{"name":"Journal of herbal pharmacotherapy","volume":"6 1","pages":"49 - 54"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/J157v06n01_05","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"60734105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
FREQUENTLY ASKED QUESTIONS (FAQ) 常见问题(faq)
Journal of herbal pharmacotherapy Pub Date : 2006-01-01 DOI: 10.1080/J157v06n01_08
Jeffrey N. Weiss
{"title":"FREQUENTLY ASKED QUESTIONS (FAQ)","authors":"Jeffrey N. Weiss","doi":"10.1080/J157v06n01_08","DOIUrl":"https://doi.org/10.1080/J157v06n01_08","url":null,"abstract":"As Americans use botanical medicines in ever-increasing numbers, they are moving beyond capsules and tinctures, and turning to assorted preparations that will complete their herbal medicine chest. According to The Arthritis Foundation, almost 45% of patients apply ointments or rubs for oseteoarthritis. Topical preparations have a long history in traditional herbal medicine systems, and make up a significant proportion of the armamentarium of indigenous practitioners. Although contemporary patients are often resistant to the inconvenience of topical preparations, they often will become compliant after a notable success. The nomenclature of these topical preparations, as one would expect, is murky. There are no clear and consistent definitions for the assorted terms, and different sources will use different terms for the same material or process.","PeriodicalId":73776,"journal":{"name":"Journal of herbal pharmacotherapy","volume":"6 1","pages":"77 - 87"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/J157v06n01_08","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"60734320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 57
Herb use among health care professionals enrolled in an online curriculum on herbs and dietary supplements. 参加草药和膳食补充剂在线课程的医疗保健专业人员使用草药。
Journal of herbal pharmacotherapy Pub Date : 2006-01-01 DOI: 10.1300/J157V06N02_05
P. Gardiner, A. Legedza, Charles R. Woods, R. Phillips, K. Kemper
{"title":"Herb use among health care professionals enrolled in an online curriculum on herbs and dietary supplements.","authors":"P. Gardiner, A. Legedza, Charles R. Woods, R. Phillips, K. Kemper","doi":"10.1300/J157V06N02_05","DOIUrl":"https://doi.org/10.1300/J157V06N02_05","url":null,"abstract":"Background: Although many adults in the United States use herbs, little is known about the personal use of herbs by health care professionals (HCPs) and factors associated with use.Methods: We performed a cross-sectional study of HCPs prior to their enrollment in an online course about herbs and dietary supplements between September 2004 and May 2005. We used multivariable logistic regression to analyze demographic and practice factors associated with herb use.Results: Of the 1249 health care professionals surveyed, 51% reported using an herb in the last week. The rates of use were highest among physician assistants or nurse practitioners (PA or NP) (63%), clinical nurses (59%), and HCP students (52%), while physicians (48%), dietitians (40%), and pharmacists (37%) had lower rates. Among health care professionals who reported herb use, the most common herbs taken were green tea (24%), flax seed (18%), chamomile (11%), and aloe vera (8%). Factors associated with herb use included older age, being a nurse, ...","PeriodicalId":73776,"journal":{"name":"Journal of herbal pharmacotherapy","volume":"6 1","pages":"51-64"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66857072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Antisecretory and Antiulcer Activity of Asparagus racemosus Willd. Against Indomethacin Plus Pyloric Ligation-Induced Gastric Ulcer in Rats 总状芦笋的抗分泌和抗溃疡活性。吲哚美辛联合幽门结扎对大鼠胃溃疡的影响
Journal of herbal pharmacotherapy Pub Date : 2006-01-01 DOI: 10.1080/J157v06n01_02
M. Bhatnagar, S. S. Sisodia
{"title":"Antisecretory and Antiulcer Activity of Asparagus racemosus Willd. Against Indomethacin Plus Pyloric Ligation-Induced Gastric Ulcer in Rats","authors":"M. Bhatnagar, S. S. Sisodia","doi":"10.1080/J157v06n01_02","DOIUrl":"https://doi.org/10.1080/J157v06n01_02","url":null,"abstract":"Objective: To study the antisecretory and antiulcer activity of Asparagus racemosus Willd. (methanolic extract) and its action against indomethacin (a non-steroidal anti-inflammatory drug) plus pyloric ligation (PL)-induced gastric ulcers in rats. Method: Indomethacin plus PL-induced gastric ulceration model was used in the study. Results: Treatment with Asparagus racemosus (Shatavari) crude extract (100 mg/kg/day orally) for fifteen days significantly reduced ulcer index when compared with control group. The reduction in gastric lesions was comparable to a standard antiulcer drug Ranitidine (30 mg/kg/ day orally). Crude extract also significantly reduced volume of gastric secretion, free acidity and total acidity. A significant increase in total carbohydrate (TC) and TC/total protein (TP) ratio of gastric juice was also observed. No significant change in the total protein was noted. Conclusion: Asparagus racemosus was found to be an effective antiulcerogenic agent, whose activity can well be compared with that of ranitidine hydrochloride. The results of this study suggest that Asparagus racemosus causes an inhibitory effect on release of gastric hydrochloric acid and protects gastric mucosal damage.","PeriodicalId":73776,"journal":{"name":"Journal of herbal pharmacotherapy","volume":"6 1","pages":"13 - 20"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/J157v06n01_02","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"60734041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 37
Fatty Acid Composition of Some Medicinally Useful Seeds 一些药用种子的脂肪酸组成
Journal of herbal pharmacotherapy Pub Date : 2006-01-01 DOI: 10.1080/J157v06n01_04
M. Srivastava, R. Banerji, A. Rawat, S. Mehrotra
{"title":"Fatty Acid Composition of Some Medicinally Useful Seeds","authors":"M. Srivastava, R. Banerji, A. Rawat, S. Mehrotra","doi":"10.1080/J157v06n01_04","DOIUrl":"https://doi.org/10.1080/J157v06n01_04","url":null,"abstract":"Fatty acid composition of seeds from the fruits of Butea monosperma, Jatropha glandulifera and Portulaca oleracea of three different families, namely Papilionaceae, Euphorbiaceae and Portulaceae were determined through Gas Liquid Chromatography to find novel natural sources of essential fatty acids for human health and of economic interest. Comparative studies were also performed to ascertain the utilization of each species for domestic as well as industrial purpose and the quality parameters developed can be utilized as marker characters for theaforesaid seeds used by the pharmaceutical industries.","PeriodicalId":73776,"journal":{"name":"Journal of herbal pharmacotherapy","volume":"6 1","pages":"41 - 47"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/J157v06n01_04","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"60734092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hypoglycemic effect of ethanolic extract of Musa sapientum on alloxan induced diabetes mellitus in rats and its relation with antioxidant potential. 麝香乙醇提取物对四氧嘧啶诱导的糖尿病大鼠的降糖作用及其与抗氧化电位的关系。
Journal of herbal pharmacotherapy Pub Date : 2005-01-01
S P Dhanabal, M Sureshkumar, M Ramanathan, B Suresh
{"title":"Hypoglycemic effect of ethanolic extract of Musa sapientum on alloxan induced diabetes mellitus in rats and its relation with antioxidant potential.","authors":"S P Dhanabal,&nbsp;M Sureshkumar,&nbsp;M Ramanathan,&nbsp;B Suresh","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The antihyperglycemic effect of ethanolic extract of flowers of Musa sapientum (Musaceae), a herb (used in Indian folklore medicine for the treatment of diabetes mellitus) in alloxan induced diabetic rats. Oral administration of the ethanolic extract showed significant (p < 0.001) blood glucose lowering effect at 200 mg/kg in alloxan induced diabetic rats (120 mg/kg, i.p.) and the extract was also found to significantly (p < 0.001) scavenge oxygen free radicals, viz., superoxide dismutase (SOD), catalase (CAT) and also protein, malondialdehyde and ascorbic acid in vivo. Musa sapientum induced blood sugar reduction may be due to possible inhibition of free radicals and subsequent inhibition of tissue damage induced by alloxan. The antidiabetic activity observed in this plant may be attributed to the presence of flavonoids, alkaloids, steroid and glycoside principles.</p>","PeriodicalId":73776,"journal":{"name":"Journal of herbal pharmacotherapy","volume":" ","pages":"7-19"},"PeriodicalIF":0.0,"publicationDate":"2005-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25665825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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