S. Otoom, Saafan A. Al-Safi, Z. Kerem, A. Alkofahi
{"title":"The Use of Medicinal Herbs by Diabetic Jordanian Patients","authors":"S. Otoom, Saafan A. Al-Safi, Z. Kerem, A. Alkofahi","doi":"10.1080/J157v06n02_03","DOIUrl":"https://doi.org/10.1080/J157v06n02_03","url":null,"abstract":"Diabetes mellitus is the most common metabolic disorder worldwide. To date, there have been no reports on the frequency of use of herb medicines in the managements of diabetes mellitus in Jordan. This cross-sectional study was conducted by interviewing 310 diabetic patients visiting two medical centers in Jordan: Jordan University of Science & Technology Medical Center and Sarih Medical Center between December 2003 and August 2004. It is found that 31% of interviewed patients have used herbal products (96 patients). The results revealed that the most commonly used herbs by diabetic patients in Jordan were Trigonella foenumgraecum (22.9%), Lupinus albus (14.6%), Alliumm sativum (11.5%), Allium cepa (5.2%), Nigella sativa (7.3%), Zea mays L. (6.3%), Urtica dioica L. (8.3%), Eucalyptus globules LA (9.4%), Olea europea L. (3.1%), Cumminum cyminum (9.4%), Coriandrum sativum (10.4%), Salvia officinalis L. (3.1%), and Tilia cordata (1%). Furthermore, it is found that 47.9% of the patients used herbs according to advice from their friends on a daily basis. The side effects were reported by 36.5% of the patients and include headache, nausea, dizziness, itching, palpitation, and sweating. Among the patients, 72.9% used the herbs as adjunctive therapy along with their anti-diabetic drugs and 80.2% of the patients informed their physicians about their use. A 79.2% of the sample confirmed their intention to re-use these herbs as 86.5% of them were satisfied with their diabetes control. There was a significant relationship between the use of herbs, the patient’s place of residence and his/her level of education. The main conclusion of this survey is that the use of medicinal herbs among diabetic patient in Jordan is common. Therefore, it is essential to increase the level of awareness among diabetic patients and health care providers regarding the efficacy and toxicity of these medicinal herbs.","PeriodicalId":73776,"journal":{"name":"Journal of herbal pharmacotherapy","volume":"6 1","pages":"31 - 41"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/J157v06n02_03","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"60734107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Gardiner, A. Legedza, Charles R. Woods, R. Phillips, K. Kemper
{"title":"Herb Use Among Health Care Professionals Enrolled in an Online Curriculum on Herbs and Dietary Supplements","authors":"P. Gardiner, A. Legedza, Charles R. Woods, R. Phillips, K. Kemper","doi":"10.1080/J157v06n02_05","DOIUrl":"https://doi.org/10.1080/J157v06n02_05","url":null,"abstract":"Background: Although many adults in the United States use herbs, little is known about the personal use of herbs by health care professionals (HCPs) and factors associated with use. Methods: We performed a cross-sectional study of HCPs prior to their enrollment in an online course about herbs and dietary supplements between September 2004 and May 2005. We used multivariable logistic regression to analyze demographic and practice factors associated with herb use. Results: Of the 1249 health care professionals surveyed, 51% reported using an herb in the last week. The rates of use were highest among physician assistants or nurse practitioners (PA or NP) (63%), clinical nurses (59%), and HCP students (52%), while physicians (48%), dietitians (40%), and pharmacists (37%) had lower rates. Among health care professionals who reported herb use, the most common herbs taken were green tea (24%), flax seed (18%), chamomile (11%), and aloe vera (8%). Factors associated with herb use included older age, being a nurse, a HCP student, an NP or PA compared with being a physician, being non-Caucasian, living outside of North Carolina and having increased knowledge of herbs and dietary supplements.","PeriodicalId":73776,"journal":{"name":"Journal of herbal pharmacotherapy","volume":"6 1","pages":"51 - 64"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/J157v06n02_05","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"60734413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The neuropharmacology of L-theanine(N-ethyl-L-glutamine): a possible neuroprotective and cognitive enhancing agent.","authors":"Pradeep J Nathan, Kristy Lu, M Gray, C Oliver","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>L-theanine (N-ethyl-L-glutamine) or theanine is a major amino acid uniquely found in green tea. L-theanine has been historically reported as a relaxing agent, prompting scientific research on its pharmacology. Animal neurochemistry studies suggest that L-theanine increases brain serotonin, dopamine, GABA levels and has micromolar affinities for AMPA, Kainate and NMDA receptors. In addition has been shown to exert neuroprotective effects in animal models possibly through its antagonistic effects on group 1 metabotrophic glutamate receptors. Behavioural studies in animals suggest improvement in learning and memory. Overall, L-theanine displays a neuropharmacology suggestive of a possible neuroprotective and cognitive enhancing agent and warrants further investigation in animals and humans.</p>","PeriodicalId":73776,"journal":{"name":"Journal of herbal pharmacotherapy","volume":"6 2","pages":"21-30"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26513087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Silvana M S Menezes, Luciana Nunes Cordeiro, Glauce S B Viana
{"title":"Punica granatum (pomegranate) extract is active against dental plaque.","authors":"Silvana M S Menezes, Luciana Nunes Cordeiro, Glauce S B Viana","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In the present work, we studied the effect of the hydroalcoholic extract (HAE) from Punica granatum (pomegranate) fruits on dental plaque microorganisms. The study was conducted on 60 healthy patients (33 females and 27 males, with age ranging from 9 to 25 years) using fixed orthodontic appliances, and randomly distributed into 3 groups of 20 patients each. The first group (control) used distilled water, while the second and third groups used chlorhexidine (standard) and HAE as mouth-rinses, respectively. The dental plaque material was collected from each patient, before and after a 1-min mouth-rinse with 15 ml of either distilled water, chlorhexidine or HAE. In both dental plaque collections, the material was removed from patients without oral hygiene, for 24 h (no tooth brushing). Dental plaque samples were diluted in phosphate buffered saline (PBS) plated on Mueller-Hinton agar, and incubated for 48 h, at 37 degrees C. Results, expressed as the number of colony forming units per milliliter (CFU/mL), show that the HAE was very effective against dental plaque microorganisms, decreasing the CFU/ml by 84% (CFU x 10(5)), before mouth-rinse: 154.0 +/- 41.18; after mouthrinse: 25.4 +/- 7.76). While similar values were observed with chlorhexidine, used as standard and positive control (79% inhibition), only an 11% inhibition of CFU/ml was demonstrated in the distilled water group, negative control (CFU x 10(5)), before mouth-rinse: chlorhexidine, 208.7 +/- 58.81 and distilled water, 81.1 +/- 10.12; after mouth-rinse: chlorhexidine, 44.0 +/- 15.85 and distilled water, 71.9 +/- 8.68). The HAE presented also an antibacterial activity against selected microorganisms, and may be a possible alternative for the treatment of dental plaque bacteria.</p>","PeriodicalId":73776,"journal":{"name":"Journal of herbal pharmacotherapy","volume":"6 2","pages":"79-92"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26513092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Analysis of Ephedra-Free Labeled Dietary Supplements Sold in the San Francisco Bay Area in 2003","authors":"J. Tam, C. Dennehy, R. Ko, C. Tsourounis","doi":"10.1080/J157V06N02_01","DOIUrl":"https://doi.org/10.1080/J157V06N02_01","url":null,"abstract":"Objective: To sample dietary supplements (DS) labeled as ephedra-free to evaluate whether products met their labeling claim. Methods: One control DS product containing ephedra alkaloids and 29 DS labeled as ephedra-free were purchased from various retail locations in San Francisco. All products were sent to the California Department of Health Services (CDHS), Food and Drug Laboratory for content and quantity analysis. All laboratory personnel were blinded to product names and labeled contents. All DS products were screened for the presence of undeclared drugs, ephedra alkaloids, and heavy metals including lead, arsenic, cadmium and mercury. All products were also evaluated for compliance with the labeling requirements of the Dietary Supplement Health and Education Act (DSHEA) of 1994. Results: None of the DS labeled as ephedra-free tested positive for the presence of ephedra alkaloids; as expected, the control product did test positive. Heavy metals were detected in three ephedra-free labeled DS products. All 24 products that tested positive for caffeine listed caffeine or a botanical source of caffeine on the DS label. All but two products were in compliance with DS labeling as required by DSHEA. Conclusions: This study demonstrates that manufacturers met their labeling claims for ephedra-free products. Special attention should be given to the presence of heavy metals and other drugs like caffeine, synephrine, and botanical sources of caffeine as these ingredients have replaced ephedra.","PeriodicalId":73776,"journal":{"name":"Journal of herbal pharmacotherapy","volume":"6 1","pages":"1 - 19"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/J157V06N02_01","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"60734433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Antioxidant Activity of Pepticare, an Herbomineral Formulation, in Experimentally Induced Renal and Cardiac Damage","authors":"P. Bafna, R. Balaraman","doi":"10.1080/J157v06n01_01","DOIUrl":"https://doi.org/10.1080/J157v06n01_01","url":null,"abstract":"Pepticare, a herbomineral formulation, was administered orally to rats at the dose levels of 125,250,500 and 1000 mg/kg to investigate its effect on isoproterenol-induced myocardial infarction and cisplatin-induced renal damage. The drug reduced the levels of serum creatine kinase (CK), glutamic oxaloacetate transaminase (GOT), lactate dehydrogenase (LDH) and uric acid in isoproterenol-induced cardiac damage. In cisplatin-induced renal damage, Pepticare reduced the serum levels of creatinine, urea, blood urea nitrogen (BUN) and uric acid. It was further found that administration of Pepticare increased the levels of superoxide dismutase (SOD), catalase (CAT), reduced glutathione (GSH), membrane bound enzymes like Ca2+ ATPase, Mg2+ ATPase and Na+ K+ATPase and decreased lipid peroxidation (MDA) in heart and kidney, respectively. Thus it can be concluded that Pepticare possesses antioxidant activity and protects the heart and kidney from damage caused by isoproterenol and cisplatin, respectively.","PeriodicalId":73776,"journal":{"name":"Journal of herbal pharmacotherapy","volume":"6 1","pages":"1 - 12"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/J157v06n01_01","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"60734481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Colon cleansing: a popular, but misunderstood natural therapy.","authors":"Steven Horne","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Intestinal inflammation and leaky gut syndrome can be at the root of many health problems. Colon cleansing is a popular therapy among alternative practitioners, but many myths surround it. The scientifically inaccurate way many traditional healers try to explain therapeutic mechanisms is one of the obstacles that inhibits dialog between traditional healers and practitioners of modern medicine. The therapy actually has clinical value, but the explanations used to promote the therapies are the stuff of herbal legends, not scientific fact. The concept of cleansing is actually a metaphorical explanation for a therapy that improves detoxification via the liver and gastrointestinal tract and reduces inflammation or irritation to mucous membranes of the GI tract.</p>","PeriodicalId":73776,"journal":{"name":"Journal of herbal pharmacotherapy","volume":"6 2","pages":"93-100"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26513093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dana A Hackman, Nicole Giese, John S Markowitz, Adam McLean, Steven G Ottariano, Chris Tonelli, Wendy Weissner, Shannon Welch, Catherine Ulbricht
{"title":"Agave (Agave americana): an evidence-based systematic review by the natural standard research collaboration.","authors":"Dana A Hackman, Nicole Giese, John S Markowitz, Adam McLean, Steven G Ottariano, Chris Tonelli, Wendy Weissner, Shannon Welch, Catherine Ulbricht","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>An evidence-based systematic review including written and statistical analysis of scientific literature, expert opinion, folkloric precedent, history, pharmacology, kinetics/dynamics, interactions, adverse effects, toxicology, and dosing.</p>","PeriodicalId":73776,"journal":{"name":"Journal of herbal pharmacotherapy","volume":"6 2","pages":"101-22"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26513094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kathryn T Knecht, Hoa Nguyen, Adrienne D Auker, David H Kinder
{"title":"Effects of extracts of lupine seed on blood glucose levels in glucose resistant mice: antihyperglycemic effects of Lupinus albus (white lupine, Egypt) and Lupinus caudatus (tailcup lupine, Mesa Verde National Park).","authors":"Kathryn T Knecht, Hoa Nguyen, Adrienne D Auker, David H Kinder","doi":"10.1080/j157v06n03_04","DOIUrl":"https://doi.org/10.1080/j157v06n03_04","url":null,"abstract":"<p><p>Lupine is a medicinal food plant with potential value in the management of diabetes. In white mice, extracts of seeds of the white lupine [Lupinus albus (L. termis L.)] were associated with increased tolerance to an oral glucose bolus. Antihyperglycemic activity was present in extracts of the whole seed but not extracts of the seed coat, and was not detected when glucose was administered intraperitoneally rather than orally. However, in contrast to results seen with the prescription drug, acarbose, lupine extract did not appear to increase the bulk or carbohydrate content of the feces. Antihyperglycemic activity was also seen in extracts of the tailcup lupine (L. caudatus) found in the Four Corners Region of the United States.</p>","PeriodicalId":73776,"journal":{"name":"Journal of herbal pharmacotherapy","volume":"6 3-4","pages":"89-104"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/j157v06n03_04","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26568161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ethan Basch, Steve Bent, Ivo Foppa, Sadaf Haskmi, David Kroll, Michelle Mele, Philippe Szapary, Catherine Ulbricht, Mamta Vora, Sophanna Yong
{"title":"Marigold (Calendula officinalis L.): an evidence-based systematic review by the Natural Standard Research Collaboration.","authors":"Ethan Basch, Steve Bent, Ivo Foppa, Sadaf Haskmi, David Kroll, Michelle Mele, Philippe Szapary, Catherine Ulbricht, Mamta Vora, Sophanna Yong","doi":"10.1080/j157v06n03_08","DOIUrl":"https://doi.org/10.1080/j157v06n03_08","url":null,"abstract":"<p><p>An evidence-based systematic review including written and statistical analysis of scientific literature, expert opinion, folkloric precedent, history, pharmacology, kinetics/dynamics, interactions, adverse effects, toxicology and dosing.</p>","PeriodicalId":73776,"journal":{"name":"Journal of herbal pharmacotherapy","volume":"6 3-4","pages":"135-59"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/j157v06n03_08","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26568165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}