Journal of environmental exposure assessment最新文献_第2页

Tools for planning large-scale measurement surveys for the assessment of indoor environmental pollutants: the case of radon 规划大规模测量调查以评估室内环境污染物的工具：氡的案例

Journal of environmental exposure assessment Pub Date : 2023-12-29 DOI: 10.20517/jeea.2023.34

Francesco Salvi

引用次数: 0

Chlorinated paraffin metabolism and its importance for understanding CP toxicity 氯化石蜡代谢及其对CP毒性认识的重要性

Journal of environmental exposure assessment Pub Date : 2023-11-15 DOI: 10.20517/jeea.2023.35

Per Ola Darnerud

引用次数: 0

Thirdhand vaping exposures are associated with pulmonary and systemic inflammation in a mouse model 在小鼠模型中，三手电子烟暴露与肺部和全身炎症有关

Journal of environmental exposure assessment Pub Date : 2023-10-30 DOI: 10.20517/jeea.2023.27

Sarah Commodore, Shikha Sharma, Carolyn Damilola Ekpruke, Robert Pepin, Angela M. Hansen, Dustin Rousselle, Maksat Babayev, Jonas M. Ndeke, Rachel Alford, Erik Parker, Stephanie Dickinson, Sunita Sharma, Patricia Silveyra

{"title":"Thirdhand vaping exposures are associated with pulmonary and systemic inflammation in a mouse model","authors":"Sarah Commodore, Shikha Sharma, Carolyn Damilola Ekpruke, Robert Pepin, Angela M. Hansen, Dustin Rousselle, Maksat Babayev, Jonas M. Ndeke, Rachel Alford, Erik Parker, Stephanie Dickinson, Sunita Sharma, Patricia Silveyra","doi":"10.20517/jeea.2023.27","DOIUrl":"https://doi.org/10.20517/jeea.2023.27","url":null,"abstract":"Thirdhand smoke (THS) is the accumulation of secondhand smoke on surfaces that ages with time. THS exposure is a potential health threat to children, partners of smokers, and workers in environments with current or past smoking, and needs further investigation. In this study, we hypothesized that thirdhand Electronic Nicotine Delivery Systems (ENDS) exposures elicit lung and systemic inflammation due to resuspended particulate matter (PM) and inorganic compounds that remain after active vaping has ceased. To test our hypothesis, we exposed C57BL/6J mice to cotton towels contaminated with ENDS aerosols from unflavored vape fluid (6 mg nicotine in 50/50 propylene glycol/vegetable glycerin) for 1h/day, five days/week, for three weeks. We assessed protein levels in serum and bronchoalveolar lavage fluid (BALF) using a multiplex protein assay. The mean ± sd for PM10 and PM2.5 measurements in exposed mouse cages were 8.3 ± 14.0 and 4.6 ± 7.5 µg/m3, compared to 6.1 ± 11.2 and 3.7 ± 6.6 µg/m3 in control cages respectively. Two compounds, 4-methyl-1, 2-dioxolane and 4-methyl-cyclohexanol, were detected in vape fluid and on ENDS-contaminated towels, but not on control towels. Mice exposed to ENDS-contaminated towels had lower levels of serum Il-7 (P = 0.022, n = 7), and higher levels of Il-13 in the BALF (P = 0.006, n = 7) than those exposed to control towels (n = 6). After adjusting for sex and age, Il-7 and Il-13 levels were still associated with thirdhand vaping exposure (P = 0.010 and P = 0.017, respectively). This study provides further evidence that thirdhand ENDS aerosols can contaminate surfaces, and subsequently influence lung and systemic health upon exposure.","PeriodicalId":73738,"journal":{"name":"Journal of environmental exposure assessment","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136067761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tissue-specific bioaccumulation and health risks of bisphenols in wild fish from West and North Rivers, South China 华南西、北河流野生鱼类双酚类物质的组织特异性生物积累及健康风险

Journal of environmental exposure assessment Pub Date : 2023-10-17 DOI: 10.20517/jeea.2023.26

Yue-Hong Liu, Jun-Wei Huang, Zheng Huang, Yu-Xian Mei, Jian-Liang Zhao, Guang-Guo Ying

{"title":"Tissue-specific bioaccumulation and health risks of bisphenols in wild fish from West and North Rivers, South China","authors":"Yue-Hong Liu, Jun-Wei Huang, Zheng Huang, Yu-Xian Mei, Jian-Liang Zhao, Guang-Guo Ying","doi":"10.20517/jeea.2023.26","DOIUrl":"https://doi.org/10.20517/jeea.2023.26","url":null,"abstract":"Bisphenols (BPs) are endocrine disruptors (EDCs) that produce hormone effects and other toxic effects. Due to their widespread use, BPs enter into the environment, such as rivers, and hence may accumulate in aquatic organisms. In this study, we investigated the tissue-specific bioaccumulation of BPs in different wild fish species in the North and West Rivers of the Pearl River system, South China, and assessed the human health risks via fish consumption. Firstly, the pretreatment method for 15 BPs in different fish tissues (muscle, liver, bile, plasma, intestine, and stomach) was established, and the target BPs were analyzed using ultra-high-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). The total concentration of BPs in surface water was up to 1,530 ng/L. Bisphenol A (BPA), bisphenol F (BPF), and bisphenol F (BPF) were the dominant ingredients. BPs were widely detected in fish tissues. Among them, BPF had the highest detection efficiency and the concentration in fish muscle and liver tissues were 401 and 6,257 ng/g ww, respectively. BPA and BPAF had the highest detection efficiencies, with concentrations of 434 and 357 ng/g ww in intestine, respectively, and of 14 and 26 ng/g ww in stomach, respectively. BPA had the highest detection efficiency and concentration in fish bile up to 17,160 ng/mL. BPAF had the highest detection efficiency and concentration of 8 ng/g ww in fish plasma. Liver and intestine showed log bioaccumulation factors up to 6.93 L/kg, exhibiting high bioaccumulation ability for BPs into biota. The hazard quotients of human exposure risks of BPA via consumption of fish muscle were in the range of 4.97 × 10-4-8.97 × 10-4, indicating a low health risk of BPA through daily fish consumption.","PeriodicalId":73738,"journal":{"name":"Journal of environmental exposure assessment","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135995182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Considerations for conducting wastewater-based public health assessments in migrant populations 对移徙人口进行基于废水的公共卫生评估的考虑

Journal of environmental exposure assessment Pub Date : 2023-10-16 DOI: 10.20517/jeea.2023.24

Devin A. Bowes, Muhammad H. Zaman

{"title":"Considerations for conducting wastewater-based public health assessments in migrant populations","authors":"Devin A. Bowes, Muhammad H. Zaman","doi":"10.20517/jeea.2023.24","DOIUrl":"https://doi.org/10.20517/jeea.2023.24","url":null,"abstract":"Wastewater-based epidemiology (WBE) provides the ability to generate inclusive and comprehensive population-level health assessments of communities. Recent work suggests these inherent benefits of WBE can serve to support vulnerable communities worldwide, such as migrant populations. The topic of forced migration has gained significant attention in recent decades as conflict and climate change events have increasingly become major drivers of migration around the world. However, information on the health of displaced populations during times of active mobility is lacking due to several logistical and ethical challenges using conventional methods. As environmental, political, and humanitarian conditions continue to evolve, it appears necessary to pursue alternative and adaptable approaches to acquire the health status of such dynamic and vulnerable populations. Here, we propose a call to action to apply WBE in migrant populations to offer inclusive and minimally invasive health assessments in order to: (1) close data gaps in the health information of displaced populations actively traveling along migratory pathways; and (2) promote greater efficacy in deployed interventions. Suggestions to pursue urgent migrant-specific health priorities are proposed, including antimicrobial resistance (AMR), infectious diseases, and malnutrition, along with considerations to promote ethically sound investigation. Overall, these recommendations may serve as a foundation to support subsequent investigation, with the purpose of encouraging global collaboration to offer new insights into the health of migrant and/or forcibly displaced populations.","PeriodicalId":73738,"journal":{"name":"Journal of environmental exposure assessment","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136114374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chemicals in personal care products: an important but understudied exposure source for both the human body and ecosystems 个人护理产品中的化学物质:对人体和生态系统的重要但尚未充分研究的暴露源

Journal of environmental exposure assessment Pub Date : 2023-10-08 DOI: 10.20517/jeea.2023.31

Nan Lin

引用次数: 0

Pollution status, distribution, source analysis, and risk assessment of OCPs in soil from the Hexi Corridor in Northwest China 河西走廊土壤OCPs污染现状、分布、来源分析及风险评价

Journal of environmental exposure assessment Pub Date : 2023-08-29 DOI: 10.20517/jeea.2023.22

Rui He, Long-miao Yuan, Yufeng Jiang, Zhanrong Jia, W. Ding, Zhongwei Yang

{"title":"Pollution status, distribution, source analysis, and risk assessment of OCPs in soil from the Hexi Corridor in Northwest China","authors":"Rui He, Long-miao Yuan, Yufeng Jiang, Zhanrong Jia, W. Ding, Zhongwei Yang","doi":"10.20517/jeea.2023.22","DOIUrl":"https://doi.org/10.20517/jeea.2023.22","url":null,"abstract":"Since OCPs with different historical usage and atmospheric input may show varied environmental behaviors and risks to the local residents and relevant research on underdeveloped areas in the middle latitudes of China is lacking, it is essential to classify the contamination status and sources of OCPs from these middle latitudes areas and to evaluate the related health risks to humans. Fifty soil samples were collected and analyzed within five cities in the Hexi Corridor in Northwest China. The ranges of ∑24OCPs, ∑DDTs, and ∑HCHs concentrations in the soil samples were 23.1-393 ng/g, 4.96-167 ng/g, and 3.40-97.5 ng/g, respectively. The residual OCPs in soil were dominated by DDTs and HCHs, accounting for 38.7% and 16.1% of ∑24OCPs. Source analysis shows that the HCHs come from historical application and possible recent pesticide use, and DDTs are mainly from early application residues that formed in aerobic environments created by agriculture ploughing, which aerates the soil. The risk assessment showed that the soil in the Hexi Corridor may have a potential risk of residual OCPs, and the carcinogenic risk (CR) was 1.90 × 10-7-6.12 × 10-7 for adults and 5.6 × 10-7-1.8 × 10-6 for children, but the hazardous index (HI) was 0.0093 to 0.2817 for adults and 0.032 to 0.932 for children. Only a few samples showed values higher than the acceptable range for children. Therefore, in this study area, there is a low health risk to local residents. Nevertheless, our results provide a strong rationale for ongoing risk assessment and management and, hopefully, eradication of OCPs in the environment.","PeriodicalId":73738,"journal":{"name":"Journal of environmental exposure assessment","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48418329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Wastewater monitoring of a community COVID-19 outbreak in a Spanish municipality 西班牙一市新冠肺炎社区爆发的废水监测

Journal of environmental exposure assessment Pub Date : 2023-08-28 DOI: 10.20517/jeea.2023.05

María Barberá-Riera, R. Llanos, M. Barneo-Muñoz, L. Bijlsma, A. Celma, Iñaki Comas, B. Gomila, F. González-Candelas, Rafael Goterris-Cerisuelo, Fernando Martínez-García, Ernesto Santateresa, M. Torres-Puente, N. Zamorano-López, Rafael Bretón-Ramos, Eduardo Aguilar-Perdiguer, M. Rebagliato, J. Bellido-Blasco, Félix Hernández

{"title":"Wastewater monitoring of a community COVID-19 outbreak in a Spanish municipality","authors":"María Barberá-Riera, R. Llanos, M. Barneo-Muñoz, L. Bijlsma, A. Celma, Iñaki Comas, B. Gomila, F. González-Candelas, Rafael Goterris-Cerisuelo, Fernando Martínez-García, Ernesto Santateresa, M. Torres-Puente, N. Zamorano-López, Rafael Bretón-Ramos, Eduardo Aguilar-Perdiguer, M. Rebagliato, J. Bellido-Blasco, Félix Hernández","doi":"10.20517/jeea.2023.05","DOIUrl":"https://doi.org/10.20517/jeea.2023.05","url":null,"abstract":"Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) wastewater surveillance has become an increasingly important tool since the initial moments of the coronavirus disease (COVID-19) pandemic, mainly conducted at a large population scale. However, the large-sized sewersheds may not provide suitable information for monitoring localized outbreaks. After the declaration of a community COVID-19 outbreak in two neighborhoods of Castellón (Spain), SARS-CoV-2 RNA levels were monitored in wastewater samples. Moreover, genomic sequencing was performed. Thirty-three samples were collected in 2020, distributed over three points of the sewage network, two of which were close to the areas where the cases were declared. The third point was located at the inlet of the municipal wastewater treatment plant (WWTP). The samples were analyzed by RT-qPCR, using specific N1 and N2 target regions. The sum of confirmed cases, with the date of symptoms onset within the 3 weeks before each sampling day, was calculated. SARS-CoV-2 RNA was detected on most days in the two sampling points at neighborhood level, and the detection became negative when the number of cases with symptoms onset during the last 21 days in the study areas decreased to 0 or 1 case. The genomic sequencing performed for RNA from wastewater and clinical samples showed the same variant. The detection of SARS-CoV-2 and the subsequent non-detection provided the epidemiologists in charge of controlling the outbreak with useful information to confirm its closure, complementing the clinical and epidemiological data. Our findings illustrate the value of wastewater surveillance for localized outbreaks, especially in situations of low incidence of COVID-19 at the broader community level.","PeriodicalId":73738,"journal":{"name":"Journal of environmental exposure assessment","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46724832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The metabolism of novel flame retardants and the internal exposure and toxicity of their major metabolites in fauna - a review 新型阻燃剂的代谢及其主要代谢物在动物体内的暴露和毒性研究进展

Journal of environmental exposure assessment Pub Date : 2023-01-01 DOI: 10.20517/jeea.2023.08

Rui Hou, Chuansheng Sun, Siqi Zhang, Qianyi Huang, Shan Liu, Lang Lin, Hengxiang Li, Xiangrong Xu

{"title":"The metabolism of novel flame retardants and the internal exposure and toxicity of their major metabolites in fauna - a review","authors":"Rui Hou, Chuansheng Sun, Siqi Zhang, Qianyi Huang, Shan Liu, Lang Lin, Hengxiang Li, Xiangrong Xu","doi":"10.20517/jeea.2023.08","DOIUrl":"https://doi.org/10.20517/jeea.2023.08","url":null,"abstract":"The worldwide production and usage of novel flame retardants increase their exposure to non-human fauna. Animals can accumulate and metabolize these novel flame retardants including novel halogenated flame retardants (NHFRs) and organophosphate flame retardants (OPFRs), which is of considerable significance to their internal exposure and final toxicities. In this review, recent studies on the metabolic pathways and kinetics of the two classes of novel flame retardants and the internal exposure and toxicity of their major metabolites are summarized. The results showed that the metabolic pathways of OPFRs were similar among various animals, while the metabolism kinetics (or toxicokinetics) were variable among species. O-dealkylation, hydroxylation and phase II conjunction were the most likely pathways for OPFRs. NHFRs might be metabolized through the pathways of debromination, hydroxylation, dealkylation, and phase II conjunction. We also suggested that di-alkyl phosphates (DAPs) and hydroxylated OPFRs (OH-OPFRs) were the predominant metabolites in the animal body. DAPs, 2,3,4,5-tetrabromobenzoic acid (TBBA) and 2-ethylhexyl tetrabromophthalate (TBMEHP) have relatively higher internal exposure levels in fauna, which might attribute to their high conversion rate and stability in the body. The metabolism of OPFRs and NHFRs in non-human animals may eliminate their acute toxicity but not their chronic toxicities (especially for endocrine-disrupting effects), which suggests attention should also be paid to the major metabolites. Based on the issues mentioned above, we proposed that the metabolic processes in multitrophic organisms, the transfer of major metabolites across the food web, and the co-exposure of the novel flame retardants and their metabolites in fauna are worth studying in the future.","PeriodicalId":73738,"journal":{"name":"Journal of environmental exposure assessment","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67658082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Variation in metal concentration across tree organs and stands: implications for reference specimen development 金属浓度在树木器官和林分上的变化:对参考标本发育的影响

Journal of environmental exposure assessment Pub Date : 2023-01-01 DOI: 10.20517/jeea.2023.09

G. O’Sullivan, Kevin Hayes, Alex Ursino, E. Hart

{"title":"Variation in metal concentration across tree organs and stands: implications for reference specimen development","authors":"G. O’Sullivan, Kevin Hayes, Alex Ursino, E. Hart","doi":"10.20517/jeea.2023.09","DOIUrl":"https://doi.org/10.20517/jeea.2023.09","url":null,"abstract":"Air pollution is a major environmental and public health issue in urban areas. Biomonitoring using trees has been widely used to determine atmospheric pollution due to its advantages of low cost, high spatial distribution, and accumulation of a wide range of air contaminants. However, challenges exist in applying the data obtained from biomonitoring trees, including differences in pollutant concentrations in samples of the same species from different locations, and the influence of biological and environmental parameters on metal accumulation. This study aims to inform the design of biomonitoring sampling for urban air quality studies and increase their applications to exposure assessment. Specifically, the study evaluates the variation in metal concentration in tree organs of two regionally relevant tree species (Picea pungens and Populus Alba), explores the implications of different aspects of field sampling, such as variation within tree stands, tree age, and develops a reference specimen to establish threshold values for differentiating between background levels and increased exposure. The results provide insight into the complexity of using biomonitoring trees for exposure assessment and the importance of considering multiple factors in study design.","PeriodicalId":73738,"journal":{"name":"Journal of environmental exposure assessment","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67658127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0