Leah M. Clarke, Jake W. O’Brien, Aimee K. Murray, Wll Gaze, Kevin V. Thomas
{"title":"A review of wastewater-based epidemiology for antimicrobial resistance surveillance","authors":"Leah M. Clarke, Jake W. O’Brien, Aimee K. Murray, Wll Gaze, Kevin V. Thomas","doi":"10.20517/jeea.2023.29","DOIUrl":"https://doi.org/10.20517/jeea.2023.29","url":null,"abstract":"Antimicrobial resistance (AMR) is recognized as one of the most serious threats to public health. Unparalleled population growth and accelerated rates of AMR emergence and dissemination have resulted in both novel resistance in pathogenic organisms and the re-appearance of infections that were formerly under control. Consequently, this has led to an increased quantity of infectious diseases. One of the main drivers of antimicrobial overuse is inappropriate prescribing in human and veterinary medicine. The ability to rapidly survey the spread of antimicrobial resistance within human populations is key for its prevention, intervention, and control. However, many constraints are present for current clinical surveillance systems and their capacity to determine AMR dynamics in the microbiome of healthy individuals as well as in clinical pathogens causing infections. Wastewater-based epidemiology (WBE) is an emergent technique that has the capacity to act as a supplementary measure for current infectious disease surveillance systems and as an early warning system for infectious disease outbreaks. The development of disease outbreaks to the community level can be monitored in real time through the analysis of population pooled wastewater. This review provides an introduction to using wastewater-based epidemiology to monitor AMR bacteria, as well as an overview of wastewater-based epidemiology and its components.","PeriodicalId":73738,"journal":{"name":"Journal of environmental exposure assessment","volume":" 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140209904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessment of the impact of sampler housing on indoor passive air sampler measurements of SVOCs","authors":"S. Vojta, L. Melymuk, R. Prokes, J. Klánová","doi":"10.20517/jeea.2023.39","DOIUrl":"https://doi.org/10.20517/jeea.2023.39","url":null,"abstract":"Passive air sampling (PAS) using a polyurethane foam (PUF) sorbent is a widely used technique to characterize air concentrations of semi-volatile organic compounds (SVOCs) in indoor environments; however, there is little consensus on the type of housing used in sampler housings and how sampler masses are converted to air concentration. We systematically evaluate the three types of PUF-PAS sampler housings most commonly used indoors, and characterize uptake rates for > 50 SVOCs, covering legacy persistent organic pollutants, pesticides, combustion by-products, and flame retardants for all three housing types. There is a clear association between the amount of shielding of the PUF disk and equivalent air volumes for PUF-PAS, with median sampling rates for double-bowl housings of 0.72 m3/day (0.62-0.92 m3/day), 1.3 m3/day (1.0-1.7 m3/day) for single bowl, and 1.8 m3/day (1.4-2.2 m3/day) for PUFs without any housing. Combining these outcomes with a meta-analysis of existing data on PUF-PAS indoor uptake, we provide recommendations for the range of applicability and selection of sampling rates for PUF-PAS in indoor environments.","PeriodicalId":73738,"journal":{"name":"Journal of environmental exposure assessment","volume":"245 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140482263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Siebe Lievens, Shanshan Yin, Lidia Belova, Yukiko Fujii, Jasper Bombeke, Jeroen De Smet, M. V. D. Borght, A. Covaci, Giulia Poma
{"title":"Bioaccumulation and biotransformation of plasticisers diisononyl phthalate and di(2-ethylhexyl) terephthalate in black soldier fly larvae reared on (micro)plastic-contaminated food waste","authors":"Siebe Lievens, Shanshan Yin, Lidia Belova, Yukiko Fujii, Jasper Bombeke, Jeroen De Smet, M. V. D. Borght, A. Covaci, Giulia Poma","doi":"10.20517/jeea.2023.46","DOIUrl":"https://doi.org/10.20517/jeea.2023.46","url":null,"abstract":"Food waste is currently used for the production of biogas. However, a reusage of waste is preferred to follow the principles of the circular economy and consider the waste management hierarchy, which can be achieved by rearing black soldier fly (BSF) larvae on such organic waste. Nonetheless, the presence of (micro)plastics and related additive plasticisers might induce chemical safety hazards to the larval applications as feed. Therefore, the bioaccumulation and biotransformation of two plasticisers (diisononyl phthalate (DINP) and di(2-ethylhexyl) terephthalate (DEHT)) in BSF larvae reared on food waste streams contaminated with polyvinyl chloride (PVC) (micro)plastics were investigated. Results showed that BSF larvae appeared to have a moderate intake of DINP during its rearing phase of 10 days (82 - 273 ng/g), while being able to biotransform it into the primary biotransformation product monoisononyl phthalate (MINP) within 24 h. For DEHT, an uptake of 67 - 137 ng/g was measured in the BSF larvae; however, no clear biotransformation pattern was observed. In addition, while no secondary oxidative biotransformation products were found in the larvae, these were measured in the frass, leading to the hypothesis that microorganism-mediated biotransformation of plasticisers occurred. In conclusion, based on the results of this study, BSF larvae could potentially be used safely in the frame of circular economy, when reared on organic substrates contaminated with the same PVC microplastic content and sizes used.","PeriodicalId":73738,"journal":{"name":"Journal of environmental exposure assessment","volume":"29 19","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139595640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Tools for planning large-scale measurement surveys for the assessment of indoor environmental pollutants: the case of radon","authors":"Francesco Salvi","doi":"10.20517/jeea.2023.34","DOIUrl":"https://doi.org/10.20517/jeea.2023.34","url":null,"abstract":"Risks from indoor pollutants require the implementation of effective policies to prevent and reduce exposure. To take decisions and actions, competent authorities need relevant information. In the case of indoor radon exposure, surveys are carried out by installing detectors in buildings (homes, workplaces) that measure radon concentration in rooms. Conducting national or large-scale surveys in buildings requires addressing both technical complexities of implementation and economic costs. In order to support the implementation of large-scale radon surveys, procedure and tools are described for defining the sample size of buildings to be measured according to available resources, for planning the sampling of buildings in relation to the specific objectives of the survey, and for obtaining a tool for management and control of sample recruitment and installation of radon detectors in buildings, reducing sources of bias. A particular application is shown for the case of the EU radon regulation.","PeriodicalId":73738,"journal":{"name":"Journal of environmental exposure assessment","volume":" 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139143464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Chlorinated paraffin metabolism and its importance for understanding CP toxicity","authors":"Per Ola Darnerud","doi":"10.20517/jeea.2023.35","DOIUrl":"https://doi.org/10.20517/jeea.2023.35","url":null,"abstract":"Chlorinated paraffins (CPs) are industrial chemicals with broad use as plasticizers and components in paints, cutting and drilling oil additives. The research interest in CPs has recently increased, not least due to the progress in analytical techniques and the globally reported large production volumes of CPs. The adverse effects on CPs in biota and in man are being reported in an increasing number of articles and the mechanism of toxicity is being discussed. Whether the metabolism of CPs could increase their toxicity is, however, still an unsolved question. In this Perspective paper, CP metabolism is discussed and arguments pointing to the important role of metabolic enhancement in CP toxicity are highlighted.","PeriodicalId":73738,"journal":{"name":"Journal of environmental exposure assessment","volume":"12 7","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136227792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sarah Commodore, Shikha Sharma, Carolyn Damilola Ekpruke, Robert Pepin, Angela M. Hansen, Dustin Rousselle, Maksat Babayev, Jonas M. Ndeke, Rachel Alford, Erik Parker, Stephanie Dickinson, Sunita Sharma, Patricia Silveyra
{"title":"Thirdhand vaping exposures are associated with pulmonary and systemic inflammation in a mouse model","authors":"Sarah Commodore, Shikha Sharma, Carolyn Damilola Ekpruke, Robert Pepin, Angela M. Hansen, Dustin Rousselle, Maksat Babayev, Jonas M. Ndeke, Rachel Alford, Erik Parker, Stephanie Dickinson, Sunita Sharma, Patricia Silveyra","doi":"10.20517/jeea.2023.27","DOIUrl":"https://doi.org/10.20517/jeea.2023.27","url":null,"abstract":"Thirdhand smoke (THS) is the accumulation of secondhand smoke on surfaces that ages with time. THS exposure is a potential health threat to children, partners of smokers, and workers in environments with current or past smoking, and needs further investigation. In this study, we hypothesized that thirdhand Electronic Nicotine Delivery Systems (ENDS) exposures elicit lung and systemic inflammation due to resuspended particulate matter (PM) and inorganic compounds that remain after active vaping has ceased. To test our hypothesis, we exposed C57BL/6J mice to cotton towels contaminated with ENDS aerosols from unflavored vape fluid (6 mg nicotine in 50/50 propylene glycol/vegetable glycerin) for 1h/day, five days/week, for three weeks. We assessed protein levels in serum and bronchoalveolar lavage fluid (BALF) using a multiplex protein assay. The mean ± sd for PM10 and PM2.5 measurements in exposed mouse cages were 8.3 ± 14.0 and 4.6 ± 7.5 µg/m3, compared to 6.1 ± 11.2 and 3.7 ± 6.6 µg/m3 in control cages respectively. Two compounds, 4-methyl-1, 2-dioxolane and 4-methyl-cyclohexanol, were detected in vape fluid and on ENDS-contaminated towels, but not on control towels. Mice exposed to ENDS-contaminated towels had lower levels of serum Il-7 (P = 0.022, n = 7), and higher levels of Il-13 in the BALF (P = 0.006, n = 7) than those exposed to control towels (n = 6). After adjusting for sex and age, Il-7 and Il-13 levels were still associated with thirdhand vaping exposure (P = 0.010 and P = 0.017, respectively). This study provides further evidence that thirdhand ENDS aerosols can contaminate surfaces, and subsequently influence lung and systemic health upon exposure.","PeriodicalId":73738,"journal":{"name":"Journal of environmental exposure assessment","volume":"67 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136067761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Tissue-specific bioaccumulation and health risks of bisphenols in wild fish from West and North Rivers, South China","authors":"Yue-Hong Liu, Jun-Wei Huang, Zheng Huang, Yu-Xian Mei, Jian-Liang Zhao, Guang-Guo Ying","doi":"10.20517/jeea.2023.26","DOIUrl":"https://doi.org/10.20517/jeea.2023.26","url":null,"abstract":"Bisphenols (BPs) are endocrine disruptors (EDCs) that produce hormone effects and other toxic effects. Due to their widespread use, BPs enter into the environment, such as rivers, and hence may accumulate in aquatic organisms. In this study, we investigated the tissue-specific bioaccumulation of BPs in different wild fish species in the North and West Rivers of the Pearl River system, South China, and assessed the human health risks via fish consumption. Firstly, the pretreatment method for 15 BPs in different fish tissues (muscle, liver, bile, plasma, intestine, and stomach) was established, and the target BPs were analyzed using ultra-high-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). The total concentration of BPs in surface water was up to 1,530 ng/L. Bisphenol A (BPA), bisphenol F (BPF), and bisphenol F (BPF) were the dominant ingredients. BPs were widely detected in fish tissues. Among them, BPF had the highest detection efficiency and the concentration in fish muscle and liver tissues were 401 and 6,257 ng/g ww, respectively. BPA and BPAF had the highest detection efficiencies, with concentrations of 434 and 357 ng/g ww in intestine, respectively, and of 14 and 26 ng/g ww in stomach, respectively. BPA had the highest detection efficiency and concentration in fish bile up to 17,160 ng/mL. BPAF had the highest detection efficiency and concentration of 8 ng/g ww in fish plasma. Liver and intestine showed log bioaccumulation factors up to 6.93 L/kg, exhibiting high bioaccumulation ability for BPs into biota. The hazard quotients of human exposure risks of BPA via consumption of fish muscle were in the range of 4.97 × 10-4-8.97 × 10-4, indicating a low health risk of BPA through daily fish consumption.","PeriodicalId":73738,"journal":{"name":"Journal of environmental exposure assessment","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135995182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Considerations for conducting wastewater-based public health assessments in migrant populations","authors":"Devin A. Bowes, Muhammad H. Zaman","doi":"10.20517/jeea.2023.24","DOIUrl":"https://doi.org/10.20517/jeea.2023.24","url":null,"abstract":"Wastewater-based epidemiology (WBE) provides the ability to generate inclusive and comprehensive population-level health assessments of communities. Recent work suggests these inherent benefits of WBE can serve to support vulnerable communities worldwide, such as migrant populations. The topic of forced migration has gained significant attention in recent decades as conflict and climate change events have increasingly become major drivers of migration around the world. However, information on the health of displaced populations during times of active mobility is lacking due to several logistical and ethical challenges using conventional methods. As environmental, political, and humanitarian conditions continue to evolve, it appears necessary to pursue alternative and adaptable approaches to acquire the health status of such dynamic and vulnerable populations. Here, we propose a call to action to apply WBE in migrant populations to offer inclusive and minimally invasive health assessments in order to: (1) close data gaps in the health information of displaced populations actively traveling along migratory pathways; and (2) promote greater efficacy in deployed interventions. Suggestions to pursue urgent migrant-specific health priorities are proposed, including antimicrobial resistance (AMR), infectious diseases, and malnutrition, along with considerations to promote ethically sound investigation. Overall, these recommendations may serve as a foundation to support subsequent investigation, with the purpose of encouraging global collaboration to offer new insights into the health of migrant and/or forcibly displaced populations.","PeriodicalId":73738,"journal":{"name":"Journal of environmental exposure assessment","volume":"85 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136114374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Chemicals in personal care products: an important but understudied exposure source for both the human body and ecosystems","authors":"Nan Lin","doi":"10.20517/jeea.2023.31","DOIUrl":"https://doi.org/10.20517/jeea.2023.31","url":null,"abstract":"","PeriodicalId":73738,"journal":{"name":"Journal of environmental exposure assessment","volume":"66 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135198069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rui He, Long-miao Yuan, Yufeng Jiang, Zhanrong Jia, W. Ding, Zhongwei Yang
{"title":"Pollution status, distribution, source analysis, and risk assessment of OCPs in soil from the Hexi Corridor in Northwest China","authors":"Rui He, Long-miao Yuan, Yufeng Jiang, Zhanrong Jia, W. Ding, Zhongwei Yang","doi":"10.20517/jeea.2023.22","DOIUrl":"https://doi.org/10.20517/jeea.2023.22","url":null,"abstract":"Since OCPs with different historical usage and atmospheric input may show varied environmental behaviors and risks to the local residents and relevant research on underdeveloped areas in the middle latitudes of China is lacking, it is essential to classify the contamination status and sources of OCPs from these middle latitudes areas and to evaluate the related health risks to humans. Fifty soil samples were collected and analyzed within five cities in the Hexi Corridor in Northwest China. The ranges of ∑24OCPs, ∑DDTs, and ∑HCHs concentrations in the soil samples were 23.1-393 ng/g, 4.96-167 ng/g, and 3.40-97.5 ng/g, respectively. The residual OCPs in soil were dominated by DDTs and HCHs, accounting for 38.7% and 16.1% of ∑24OCPs. Source analysis shows that the HCHs come from historical application and possible recent pesticide use, and DDTs are mainly from early application residues that formed in aerobic environments created by agriculture ploughing, which aerates the soil. The risk assessment showed that the soil in the Hexi Corridor may have a potential risk of residual OCPs, and the carcinogenic risk (CR) was 1.90 × 10-7-6.12 × 10-7 for adults and 5.6 × 10-7-1.8 × 10-6 for children, but the hazardous index (HI) was 0.0093 to 0.2817 for adults and 0.032 to 0.932 for children. Only a few samples showed values higher than the acceptable range for children. Therefore, in this study area, there is a low health risk to local residents. Nevertheless, our results provide a strong rationale for ongoing risk assessment and management and, hopefully, eradication of OCPs in the environment.","PeriodicalId":73738,"journal":{"name":"Journal of environmental exposure assessment","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48418329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}