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Journal of clinical and translational pathology最新文献

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Quality Assurance in Histopathology Laboratories 组织病理学实验室的质量保证
Journal of clinical and translational pathology Pub Date : 2023-11-15 DOI: 10.14218/jctp.2023.00035
Muhammed Mubarak
{"title":"Quality Assurance in Histopathology Laboratories","authors":"Muhammed Mubarak","doi":"10.14218/jctp.2023.00035","DOIUrl":"https://doi.org/10.14218/jctp.2023.00035","url":null,"abstract":"Achieving and maintaining quality is of utmost importance in laboratory operations for the best possible patient care. The concepts of quality control and related quality procedures and programs are relatively new and less well understood in histopathology laboratories than in other sections of clinical laboratories, particularly in developing countries. This is because the main product from these laboratories consists of descriptive, opinion-based reports rather than numerical reports as in other fields of laboratory medicine, and most of the work is still manual and involves multiple steps. The scope and extent of quality schemes in histopathology laboratories are very broad and complex, requiring coordinated and concerted efforts on the part of all stakeholders to achieve and maintain quality services in these laboratories. There is a need to create awareness among the pathologist community and other healthcare members about the necessity of quality assurance and improvement schemes in these laboratories to achieve optimal patient care.","PeriodicalId":73661,"journal":{"name":"Journal of clinical and translational pathology","volume":"3 10","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136229364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prognostic Significance of Tumor-infiltrating Lymphocytes and Anti-programmed Death-ligand 1 Therapy in Sinonasal Mucosal Melanoma: A 10-year Experience at a Single Institution 肿瘤浸润淋巴细胞和抗程序性死亡配体1治疗在鼻黏膜黑色素瘤中的预后意义:一个机构的10年经验
Journal of clinical and translational pathology Pub Date : 2023-09-28 DOI: 10.14218/jctp.2023.00018
Jana Tarabay, Dong Ren, Ibe Ifegu, Sherehan Zada, Robert Edwards, Jefferson Chan, Edward C. Kuan, Beverly Wang
{"title":"Prognostic Significance of Tumor-infiltrating Lymphocytes and Anti-programmed Death-ligand 1 Therapy in Sinonasal Mucosal Melanoma: A 10-year Experience at a Single Institution","authors":"Jana Tarabay, Dong Ren, Ibe Ifegu, Sherehan Zada, Robert Edwards, Jefferson Chan, Edward C. Kuan, Beverly Wang","doi":"10.14218/jctp.2023.00018","DOIUrl":"https://doi.org/10.14218/jctp.2023.00018","url":null,"abstract":"Background and objectivesSinonasal mucosal melanoma (SNMM) is a rare aggressive malignancy that presents with dismal outcomes and a high metastatic propensity. The prognostic factors as well as therapeutic regimens remain largely unknown due to the rarity of SNMM. This study aimed to assess the characteristics of SNMM patients associated with a better prognosis.","PeriodicalId":73661,"journal":{"name":"Journal of clinical and translational pathology","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135344273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Milan System for Reporting Salivary Gland Cytopathology and Updates 报告唾液腺细胞病理学和更新的米兰系统
Journal of clinical and translational pathology Pub Date : 2023-09-19 DOI: 10.14218/jctp.2023.00011
Xi Wang, He Wang
{"title":"The Milan System for Reporting Salivary Gland Cytopathology and Updates","authors":"Xi Wang, He Wang","doi":"10.14218/jctp.2023.00011","DOIUrl":"https://doi.org/10.14218/jctp.2023.00011","url":null,"abstract":"The Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) was introduced into cytopathology practice more than 5 years ago. It classifies the salivary gland lesion into 6 diagnostic categories and provides the risk of malignancy (ROM) and clinical management guidelines for each category. More than 100 articles have confirmed the applicability of this reporting system in routine practice and its important role in providing a uniform reporting system for salivary gland fine-needle aspiration. At the same time, new questions and feedback for improvement have emerged, as well as opportunities for clarification. For example, questions related to the non-diagnostic category are multiple-fold. First, although the cytologic criterion of the non-diagnostic category is currently defined as “<60 lesional cells or normal salivary gland tissue within the clinical setting of an evident mass”, this has not been established or validated in the literature. Second, the ROM for the non-diagnostic category is high. Another question surrounds the interesting topic of sub-classifying current MSRSGC categories, as the risk of malignancy could vary in tumors of the same category. The last one concerns the incorporation of the ever-increasing number of molecular markers and antibody detection of gene re-arrangements, so-called next-generation immunohistochemistry (IHC) markers, into routine cytopathology practice. The quick application of next-generation sequencing into pathology practice provides an exciting opportunity for salivary gland cytopathology diagnosis.","PeriodicalId":73661,"journal":{"name":"Journal of clinical and translational pathology","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135061243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pancreatic Acinar Cell Carcinoma Presenting as a Large Splenic Mass in a Patient with BRCA2 Germline Mutation: A Case Report 胰腺腺泡细胞癌在BRCA2种系突变患者中表现为大脾脏肿块:一例报告
Journal of clinical and translational pathology Pub Date : 2023-09-12 DOI: 10.14218/jctp.2023.00012
Kara Chan Phelps, Zhikai Chi, Lan Peng
{"title":"Pancreatic Acinar Cell Carcinoma Presenting as a Large Splenic Mass in a Patient with BRCA2 Germline Mutation: A Case Report","authors":"Kara Chan Phelps, Zhikai Chi, Lan Peng","doi":"10.14218/jctp.2023.00012","DOIUrl":"https://doi.org/10.14218/jctp.2023.00012","url":null,"abstract":"","PeriodicalId":73661,"journal":{"name":"Journal of clinical and translational pathology","volume":"66 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135887185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Plasma Cell Neoplasms with Unusual Anatomic Locations, Morphology, Phenotype, and Review of Literature: A Case Series 具有不寻常解剖位置、形态、表型和文献回顾的浆细胞肿瘤:一个病例系列
Journal of clinical and translational pathology Pub Date : 2023-09-04 DOI: 10.14218/jctp.2023.00009
Azal Alani, Jui Choudhuri, Ryan J. Malonis, Oleksii Iakymenko, Yang Shi, Qing Wang, Xuejun Tian, Yanan Fang, Yanhua Wang
{"title":"Plasma Cell Neoplasms with Unusual Anatomic Locations, Morphology, Phenotype, and Review of Literature: A Case Series","authors":"Azal Alani, Jui Choudhuri, Ryan J. Malonis, Oleksii Iakymenko, Yang Shi, Qing Wang, Xuejun Tian, Yanan Fang, Yanhua Wang","doi":"10.14218/jctp.2023.00009","DOIUrl":"https://doi.org/10.14218/jctp.2023.00009","url":null,"abstract":"Background and objectivesPlasma cell neoplasms are well-known for having diverse morphological and phenotype presentations and less commonly unusual immunophenotypical profiles. Such unexpected immunophenotypical variability could lead to inaccurate impressions upon initial assessment, thus delaying an accurate diagnosis. Here, the authors report seven plasma cell neoplasm cases with unusual morphology, immunophenotype, or unusual anatomic locations from the archives of Montefiore Medical Center Hematopathology department to highlight key considerations involved in diagnosing plasma cell neoplasms.","PeriodicalId":73661,"journal":{"name":"Journal of clinical and translational pathology","volume":"20 4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135453092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fine Needle Aspiration Cytopathology of Thymoma and Thymic Carcinoma: A Brief Review 胸腺瘤和胸腺癌的细针穿刺细胞病理学综述
Journal of clinical and translational pathology Pub Date : 2023-08-09 DOI: 10.14218/jctp.2023.00014
Zaibo Li, P. Wakely
{"title":"Fine Needle Aspiration Cytopathology of Thymoma and Thymic Carcinoma: A Brief Review","authors":"Zaibo Li, P. Wakely","doi":"10.14218/jctp.2023.00014","DOIUrl":"https://doi.org/10.14218/jctp.2023.00014","url":null,"abstract":"","PeriodicalId":73661,"journal":{"name":"Journal of clinical and translational pathology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48821480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Artificial Intelligence Increases Reliability in Diagnostic Hematooncology 人工智能提高血液学诊断的可靠性
Journal of clinical and translational pathology Pub Date : 2023-07-31 DOI: 10.14218/jctp.2023.00015
D. Starostka, Richard Dolezilek, K. Chasáková
{"title":"Artificial Intelligence Increases Reliability in Diagnostic Hematooncology","authors":"D. Starostka, Richard Dolezilek, K. Chasáková","doi":"10.14218/jctp.2023.00015","DOIUrl":"https://doi.org/10.14218/jctp.2023.00015","url":null,"abstract":"Diagnostic hematooncology is based on diverse methods of cellular and molecular analysis. Precise cytomorphological features have been defined for the classification of hema-tolymphoid neoplasms and many non-neoplastic conditions","PeriodicalId":73661,"journal":{"name":"Journal of clinical and translational pathology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41496642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Update on the Classification of Lung and Pleural Tumors 肺和胸膜肿瘤分类的最新进展
Journal of clinical and translational pathology Pub Date : 2023-06-27 DOI: 10.14218/jctp.2023.00008
Liang Lu, Haodong Xu
{"title":"An Update on the Classification of Lung and Pleural Tumors","authors":"Liang Lu, Haodong Xu","doi":"10.14218/jctp.2023.00008","DOIUrl":"https://doi.org/10.14218/jctp.2023.00008","url":null,"abstract":"The World Health Organization (WHO) recently published new guidelines for the diagnosis and classification of lung and pleural tumors. This review provides a concise overview of the key updates, including discussions of histologic features and recommended terminology for small diagnostic lung samples, the revised grading system for lung adenocarcinoma with inclusion of complex glandular and filigree micropapillary patterns, and molecular features of large cell neuroendocrine carcinoma. Additionally, rare neoplasms such as bronchiolar adenoma/ciliated muconodular papillary tumor, SMARCA4-deficient undifferentiated thoracic tumor, and primary pulmonary hyalinizing clear cell carcinoma are described in terms of their diagnostic approaches and molecular features. This review also includes discussion of the diagnostic algorithm for malignant epithelioid mesothelioma.","PeriodicalId":73661,"journal":{"name":"Journal of clinical and translational pathology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45351910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Paris System for Reporting Urinary Cytology: An Updated Review 巴黎泌尿细胞学报告系统:最新综述
Journal of clinical and translational pathology Pub Date : 2023-06-26 DOI: 10.14218/jctp.2022.00035
Fei Chen, Xiaoqi Lin
{"title":"The Paris System for Reporting Urinary Cytology: An Updated Review","authors":"Fei Chen, Xiaoqi Lin","doi":"10.14218/jctp.2022.00035","DOIUrl":"https://doi.org/10.14218/jctp.2022.00035","url":null,"abstract":"","PeriodicalId":73661,"journal":{"name":"Journal of clinical and translational pathology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42284803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The Yokohama System for Reporting Breast Cytopathology 横滨乳腺细胞病理学报告系统
Journal of clinical and translational pathology Pub Date : 2023-06-20 DOI: 10.14218/jctp.2023.00006
Wendong Yu, Qiong Gan, Y. Gong
{"title":"The Yokohama System for Reporting Breast Cytopathology","authors":"Wendong Yu, Qiong Gan, Y. Gong","doi":"10.14218/jctp.2023.00006","DOIUrl":"https://doi.org/10.14218/jctp.2023.00006","url":null,"abstract":"","PeriodicalId":73661,"journal":{"name":"Journal of clinical and translational pathology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46635523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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