Journal of clinical & experimental immunology最新文献

{"title":"To Acu or not to Puncture?","authors":"","doi":"10.33140/jcei.05.04.05","DOIUrl":"https://doi.org/10.33140/jcei.05.04.05","url":null,"abstract":"Even though acupuncture and its reputed role in Traditional Chinese Medicine appears as a true value in East & West, from heart’s “perspective” it feels really as a false value. Acupuncture behaves as a stressor. Its way of approaching the skin, and especially the sensitive mechanoreceptors, fits more in challenging the nociceptors (pain receptors), rather than any other kind of basic skin receptors, such as haptic-stretch-pressure & vibration. This kindling mechanism, this external source of algorithmical conglomerative stress onto the skin, and consequently to other biological systems of the organism which are connected/entangled with it from the embryological phase of the three germ layers, has inevitably a direct link with the autonomic nervous system; the hypothalamic-pituitary-adrenal (HPA) axis with cortisol production, and the sympathoadrenal medullary (SAM) axis which activate the sympathetic nervous system, which dedicates energy to more relevant bodily systems to acute adaptation to stress. The above-mentioned neurobiological mechanisms are the basic major systems that respond to stress, and by extension they can affect through it (stress caused by acupuncture) the immune system.","PeriodicalId":73657,"journal":{"name":"Journal of clinical & experimental immunology","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89728426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Therapeutic Apheresis in Pediatrics with Neurological and Hematological Diseases","authors":"","doi":"10.33140/jcei.05.04.04","DOIUrl":"https://doi.org/10.33140/jcei.05.04.04","url":null,"abstract":"The advantages of therapeutic apheresis (TA) with hollow fiber membranes are a complete separation of the corpuscular components from the plasma and due to increased blood flow rate higher efficacy [1]. The use of therapeutic apheresis in pediatric patients, which increasing more and more, has always been restricted by technical difficulties and the low incidence of diseases requiring this kind of treatment. The development of new, more sophisticated membranes and new adsorption technologies allow the most selective separation of plasma components. TA has been successfully introduced in a variety of autoantibody-mediated diseases [2]. The updated information on immunology and molecular biology of different neurological and hematological diseases are discussed in relation to the rationale for apheresis therapy and its place in combination with other modern treatments. The different diseases can be treated by various apheresis methods. Pathogenetical aspects are demonstrated in these diseases, in which they are clarified. TA has been shown to effectively remove the autoantibodies from blood and lead to rapid clinical improvement. For the neurological and hematological diseases, which can be treated with TA, the guidelines of the Apheresis Application Committee (AAC) of the American Society for Apheresis (ASFA) are cited [3, 4].","PeriodicalId":73657,"journal":{"name":"Journal of clinical & experimental immunology","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78449659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Escaping Cytokine Storm for the Poor","authors":"","doi":"10.33140/jcei.05.04.03","DOIUrl":"https://doi.org/10.33140/jcei.05.04.03","url":null,"abstract":"Since the Covid 19 broke out, people are all looking for the cure. Many people died from this fat al disease; and cytokine storm is one of the most dangerous complications. For some low-income people, they are not eligible to be tested for Covid; and they might not get the proper medical care. In these cases, self-care procedures, such as exercise, clear the airway, handwashing, wearing mask, taking meds on time, and proper diet become crucial in deciding the prognoses. This research is about a case study of a patient who is not eligible for a Covid 19 lab test; and how she dealt with a severe flu-like disease.","PeriodicalId":73657,"journal":{"name":"Journal of clinical & experimental immunology","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86449812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Building up fundamental strength to fight against COVID-19 for patients with chronic diseases and complications","authors":"Gerald C. Hsu","doi":"10.33140/jcei.05.04.02","DOIUrl":"https://doi.org/10.33140/jcei.05.04.02","url":null,"abstract":"This paper describes qualitatively and quantitatively the actions to protect some patients with chronic diseases and complications during this COVID-19 period.","PeriodicalId":73657,"journal":{"name":"Journal of clinical & experimental immunology","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87874174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transplantation of Mesenchymal Stem Cells in Treating Patients with Severe\u0000COVID-19: A Systematic Review and Meta-Analysis","authors":"","doi":"10.33140/jcei.05.03.07","DOIUrl":"https://doi.org/10.33140/jcei.05.03.07","url":null,"abstract":"The objective of the study is to perform a critical review, exploration, and strong summary of the roles of mesenchymal\u0000stem cell transplantation in treating various diseases, including COVID-19. A comprehensive search was carried out\u0000in mainstream bibliographic databases or Medical Subject Headings, including Scien Direct, PubMed, Scopus, ISI Web\u0000of Science, and websites of the news. The search was applied to the articles that were published between January 2020\u0000and April 2020. Needed article information was extracted from each article by : 1) direct information including journal\u0000(research article, review article, meeting abstract, conference abstract, correspondence, author index, editorial board\u0000meeting abstract, discussion), book chapter, title, authors, abstract, full text documents of candidate studies, websites\u0000of the news, publishing year; 2) study period; 3) research (study) method used; 4) types of mesenchymal stem cells; and\u00005) types of human organ system disorder or disease studied. With strict literature search and screening processes, it\u0000yielded 6 articles from 76 articles of initial literature databases and websites of the news (January 2020 to April 2020).\u0000Anti-inflammatory and immunomodulatory properties of MSCs in the treatment of respiratory diseases were confirmed\u0000by at least 17 clinical studies and more than 70 clinical trials are registered in this issue that are available at: https://\u0000www.clinicaltrials.gov. MSC transplantation improves the treatment outcome of COVID-19 patients may be due to\u0000controlling inflammatory response and promoting tissue regeneration and repair. In conclusion, Human MSCs are\u0000currently being evaluated as a stem cell treatment for a number of diseases, particularly severe COVID-19 and have\u0000been demonstrated to be safe in clinical trials. There are some promising reports to apply MSCs therapy to treat\u0000COVID-19. MSCs may possibly be one of the most ideal therapeutics, or a combination of treatment to treat patients\u0000with COVID-19. Nevertheless, further studies are urgently needed to investigate and optimize a number of variables in\u0000the human MSC culture environment by developing a bioprocess that can be operated in accordance with the Good\u0000Manufacturing Product (GMP).","PeriodicalId":73657,"journal":{"name":"Journal of clinical & experimental immunology","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87208184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Controlling Type 2 Diabetes via Artificial Intelligence Technology (GH-Method:\u0000Math-Physical Medicine)","authors":"","doi":"10.33140/jcei.05.03.05","DOIUrl":"https://doi.org/10.33140/jcei.05.03.05","url":null,"abstract":"In this paper, the author describes his methodology of developing\u0000an artificial intelligence (AI) based Glucometer to assist diabetes\u0000patients to control their glucose and HbA1C conditions.","PeriodicalId":73657,"journal":{"name":"Journal of clinical & experimental immunology","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80127211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effective age resulting from Metabolic Changes","authors":"","doi":"10.33140/jcei.05.03.06","DOIUrl":"https://doi.org/10.33140/jcei.05.03.06","url":null,"abstract":"In this research note, the author reviewed his past 8-years data\u0000from 2012 through 2019 by focusing on the relationship between\u0000his metabolism and overall health conditions. He decided to write\u0000this paper regarding his “Effective Age” using the GH-Method:\u0000math-physical medicine approach.","PeriodicalId":73657,"journal":{"name":"Journal of clinical & experimental immunology","volume":"78 3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89974538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evolutive Immunologic and Toxicologic Approach in Some Neuroinflamatory and\u0000Degenerative Disease like SM, DA, PD","authors":"","doi":"10.33140/jcei.05.03.04","DOIUrl":"https://doi.org/10.33140/jcei.05.03.04","url":null,"abstract":"In order to better, understand some neurologic process is fundamental to use an evolutionary approach. Imaging can\u0000help in measuring efficiency of brains wasting system in the various subject. The brain glimphatic systems is well\u0000studied today but an accurate measure of the real efficiency of the system is needed. Aim of this work is to submit to the\u0000researcher a working method to measure this parameter to verify if possible to use the brain glymphatic system as new\u0000therapeutics strategy","PeriodicalId":73657,"journal":{"name":"Journal of clinical & experimental immunology","volume":"115 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87028775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lived Experiences of Individual Living with Human Immunodeficiency Virus Ages\u000018-30 in Dasmariñas City Cavite","authors":"","doi":"10.33140/jcei.05.03.02","DOIUrl":"https://doi.org/10.33140/jcei.05.03.02","url":null,"abstract":"An undergraduate thesis presented to the faculty of College of Nursing, Cavite State University, Indang Cavite, in partial fulfillment\u0000of the requirements for the degree of Bachelor of Science in Nursing, with Contribution no. SP CON NO.__________. Prepared\u0000under the supervision of Dr. Evelyn M. Del Mundo.","PeriodicalId":73657,"journal":{"name":"Journal of clinical & experimental immunology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82204948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Using GH-Method: Math-Physical Medicine, Fourier Transform, and Frequency\u0000Segmentation Pattern Analysis to Investigate Relative Energy Associated with Glucose","authors":"","doi":"10.33140/jcei.05.03.01","DOIUrl":"https://doi.org/10.33140/jcei.05.03.01","url":null,"abstract":"This paper provides research findings on glucose created relative\u0000energy by using sensor collected glucose data from a period of 376\u0000days from 5/5/2018 to 5/15/20. The dataset is provided by the author,\u0000who uses his own type 2 diabetes metabolic conditions control, as\u0000a case study via the “math-physical medicine” approach of a nontraditional methodology in medical research.\u0000Math-physical medicine (MPM) starts with the observation of the\u0000human body’s physical phenomena (not biological or chemical\u0000characteristics), collecting elements of the disease related data\u0000(preferring big data), utilizing applicable engineering modeling\u0000techniques, developing appropriate mathematical equations (not\u0000just statistical analysis), and finally predicting the direction of the\u0000development and control mechanism of the disease.","PeriodicalId":73657,"journal":{"name":"Journal of clinical & experimental immunology","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75874264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}