Journal of chemical health & safety最新文献_第8页

A Real-Time Multifactor Risk Monitoring Method for the Gas Pipeline Operation Process Based on Mix-Supervised Target Recognition 基于混合监督目标识别的天然气管道运行过程多因素实时风险监控方法

Journal of chemical health & safety Pub Date : 2024-04-16 DOI: 10.1021/acs.chas.4c00012

Denglong Ma*, Weigao Mao, Chenlei Huang, Guangsen Zhang, Yi Han, Xiaoming Zhang, Hansheng Wang and Kang Cen,

{"title":"A Real-Time Multifactor Risk Monitoring Method for the Gas Pipeline Operation Process Based on Mix-Supervised Target Recognition","authors":"Denglong Ma*, Weigao Mao, Chenlei Huang, Guangsen Zhang, Yi Han, Xiaoming Zhang, Hansheng Wang and Kang Cen, ","doi":"10.1021/acs.chas.4c00012","DOIUrl":"10.1021/acs.chas.4c00012","url":null,"abstract":"With the rapid expansion of urban gas infrastructure, significant issues such as pipeline aging have arisen, leading to an increase in gas pipeline repair operations. However, this process has also resulted in numerous safety accidents. The traditional manual supervision mode for pipeline repair processes has several limitations, including incomplete identification of risk elements and the inability to estimate risks quantitatively. To address these challenges, a safety monitoring method was put forward in this study for the visible risk elements of the gas repair operation process. This method involves the identification of five types of risk elements and the establishment of a target detection data set for gas repair operations. Moreover, a data annotation method based on mix-supervised learning is proposed, which significantly enhances data annotation efficiency and saves 50% of marking time compared with manual annotation while maintaining an acceptable level of accuracy. Additionally, a visual risk element recognition model for the gas repair process was developed by using the YOLOv5 algorithm. The test results demonstrate that the detection accuracy of the visible risk element achieved in this research is 92.9%. These findings can assist in identifying potential safety hazards for personnel, equipment, and the environment during pipeline repair operations.","PeriodicalId":73648,"journal":{"name":"Journal of chemical health & safety","volume":"31 3","pages":"259–267"},"PeriodicalIF":0.0,"publicationDate":"2024-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140572610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lessons Learned─Splashing Incidents of Methanol and ortho-Chlorobenzaldehyde into Eyes and Faces Due to Accidental Detachment of Luer Slip Syringes and Needles 经验教训──因鲁尔式注射器和针头意外脱落而导致甲醇和邻氯苯甲醛溅入眼睛和面部的事故

Journal of chemical health & safety Pub Date : 2024-04-14 DOI: 10.1021/acs.chas.4c00011

Yusuke Koshiba*, Kenji Wakui and Masahiko Ito,

{"title":"Lessons Learned─Splashing Incidents of Methanol and ortho-Chlorobenzaldehyde into Eyes and Faces Due to Accidental Detachment of Luer Slip Syringes and Needles","authors":"Yusuke Koshiba*, Kenji Wakui and Masahiko Ito, ","doi":"10.1021/acs.chas.4c00011","DOIUrl":"10.1021/acs.chas.4c00011","url":null,"abstract":"This study provides details of two incidents involving the splashing of chemicals (methanol and ortho-chlorobenzaldehyde) from Luer slip syringes into students’ eyes and faces in chemistry laboratories. The methanol incident was directly caused by unsafe acts, specifically the inappropriate use of a Luer slip syringe without adjusting the position of the clamp, which remained elevated. Additionally, the incident was a result of an unsafe condition, as the safety glasses wore by the individual were not designed as over-the-glass safety glasses, creating a gap between the student’s face and lip of the safety glasses, thereby allowing methanol to reach the student’s eyes. Unsafe acts were identified as the direct causes of the ortho-chlorobenzaldehyde incident. These acts included using an inappropriate Luer slip syringe, exerting force on a long syringe needle, conducting syringe operations outside a fume hood, and neglecting to wear appropriate safety glasses and a lab coat. Furthermore, an unsafe condition involved the inappropriate positioning of a flask within a fume hood. Consequently, detaching a needle from the Luer slip syringe resulted in the scattering of chemicals reaching the student’s face and eyes. A method that enables the multifaceted exploration of the causes of human errors and facilitates the development of comprehensive solutions was used to identify 16 root causes of human errors and 11 preventive measures for the ortho-chlorobenzaldehyde incident. The lessons learned from the two incidents contribute substantially to preventing the recurrence of similar syringe incidents and reducing the risks associated with syringe operations in chemistry laboratories that handle hazardous/toxic chemicals.","PeriodicalId":73648,"journal":{"name":"Journal of chemical health & safety","volume":"31 3","pages":"222–228"},"PeriodicalIF":0.0,"publicationDate":"2024-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140572474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intrinsic Continuous Process Safeguarding Revisited for Batch Reactions 重新审视批量反应的内在连续过程保障

Journal of chemical health & safety Pub Date : 2024-04-10 DOI: 10.1021/acs.chas.3c00095

Kees van ’t Land*, Meik Franke, Sascha Kersten and Arian Nijmeijer,

引用次数: 0

Introduction and Safe Use of Gas Cylinders in China 中国气瓶简介与安全使用

Journal of chemical health & safety Pub Date : 2024-03-26 DOI: 10.1021/acs.chas.3c00106

Li-Ye Liang, Jian-Yi Nie*, Qiang Wang*, Jian-Feng Wu* and Lingjun Chou*,

引用次数: 0

Disposable Nitrile Glove Resistance to Limonene: Dextrous Robot Hand Versus ASTM F739 Comparison 一次性丁腈手套对柠檬烯的耐受性：灵巧机器人手与 ASTM F739 的比较

Journal of chemical health & safety Pub Date : 2024-03-20 DOI: 10.1021/acs.chas.3c00117

Sean Banaee, Airek Mathews and Shane Que Hee*,

{"title":"Disposable Nitrile Glove Resistance to Limonene: Dextrous Robot Hand Versus ASTM F739 Comparison","authors":"Sean Banaee, Airek Mathews and Shane Que Hee*, ","doi":"10.1021/acs.chas.3c00117","DOIUrl":"10.1021/acs.chas.3c00117","url":null,"abstract":"The current technique to assess glove resistance to chemicals for worker protection relies on challenging a flat, 2.54 cm diameter glove piece at or near room temperature. This does not simulate a donned whole glove near the skin temperature subjected to work activity forces. Four different types of disposable nonpowdered unlined/unsupported nitrile gloves in triplicate were measured for thickness, porosity, and for the acrylonitrile content (A) of the challenge and collection sides. Limonene permeation at 35 °C through a whole glove on a clenching and nonclenching dextrous robot hand and with the standard ASTM F739 technique were facilitated by taking samples from the collection sides for GC-MS analysis. The standardized breakthrough time (SBT) when permeation reached 100 ng/cm2/min and the steady state permeation rate (SSPR) depended on A, thickness, and porosity. Only the thinnest glove (Lavender) showed statistically significant (p ≤ 0.05) increased average SSPR for the clenching hand relative to the nonclenching hand and for the ASTM technique. The ASTM test data for the three thickest gloves were not statistically different from those of the robot hand, but differed from the manufacturer’s. More research with different chemicals and higher clenching forces is needed. Clenching forces can enhance the permeation. Workers wearing ultrathin disposable nitrile gloves have a higher potential for chemical penetration/permeation. Company glove permeation data obtained near room temperature may have a longer SBT and lower SSPR than in practice. Double gloving may be advisible in emergencies and for unknown chemicals when no appropriate thicker Chemical Protective glove is available.","PeriodicalId":73648,"journal":{"name":"Journal of chemical health & safety","volume":"31 3","pages":"253–258"},"PeriodicalIF":0.0,"publicationDate":"2024-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acs.chas.3c00117","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140170111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advancing Era and Rising Concerns in Nanotechnology-Based Cancer Treatment 以纳米技术为基础的癌症治疗时代的到来与日益增长的担忧

Journal of chemical health & safety Pub Date : 2024-03-13 DOI: 10.1021/acs.chas.3c00104

Harshita Tiwari, Priyamvada Gupta, Ashish Verma, Swati Singh, Rajiv Kumar, Hemant Kumar Gautam and Vibhav Gautam*,

{"title":"Advancing Era and Rising Concerns in Nanotechnology-Based Cancer Treatment","authors":"Harshita Tiwari, Priyamvada Gupta, Ashish Verma, Swati Singh, Rajiv Kumar, Hemant Kumar Gautam and Vibhav Gautam*, ","doi":"10.1021/acs.chas.3c00104","DOIUrl":"10.1021/acs.chas.3c00104","url":null,"abstract":"Cancer is one of the most prevalent causes of mortality worldwide. The arena of cancer diagnosis and therapy has undergone a tremendous revolution since the development of nanotechnology. Due to their nanosize and biocompatibility, nanoparticles are extensively employed for gene therapy and targeted drug delivery. Nanotechnology-based approaches have also shown promising advancements in the utilization of extracellular vesicles for cancer diagnosis, prognosis, and therapy. Apart from this, the CRISPR/Cas9 (Clustered Regularly Interspaced Short Palindromic Repeats and CRISPR-associated protein 9)-based nanotherapy and the development of therapeutic nanovaccines have also demonstrated encouraging results in revolutionizing cancer treatment. Nanotechnology-based molecular imaging and contrast agents can detect cancer at very early stages, allowing for prompt treatment and better patient outcomes. Although nanoparticles offer multiple benefits for drug administration, they additionally possess certain pharmacokinetic limitations, such as body clearance, restricted tissue penetration, confrontation with biological barriers, biodistribution, and accumulation. However, improvements in nanoparticle design are intended to resolve safety issues and enhance the therapeutic effects of these particles in a variety of disease complications. While nanotechnology has demonstrated immense potential in the treatment and diagnosis of cancer, there are still several challenges to overcome, including guaranteeing the safety of nanomaterials, taking into account regulatory issues, and creating scalable and affordable solutions. Nevertheless, new developments in nanotechnology and current research hold promise for further revolutionizing cancer detection and treatment.","PeriodicalId":73648,"journal":{"name":"Journal of chemical health & safety","volume":"31 2","pages":"153–161"},"PeriodicalIF":0.0,"publicationDate":"2024-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140147611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Medical Emergency Response and Management of Tritium-Related Accidents 氚相关事故的医疗应急响应和管理

Journal of chemical health & safety Pub Date : 2024-03-12 DOI: 10.1021/acs.chas.3c00061

Nan Ma, Junchao Feng, Xiaofang Geng, Weiguo Zhao, Le Zhao, Huahui Bian, Youyou Wang, Weibo Chen, Yuhan Hou, Wenyue Chen, Yanyan Zhan and Yulong Liu*,

引用次数: 0

Turning Outsiders into Insiders: A Call for Papers to Expand the Reach of National Laboratories’ Safety Successes, Challenges, Research, and Approaches 把局外人变成局内人：为扩大国家实验室安全方面的成功、挑战、研究和方法的影响而征集论文

Journal of chemical health & safety Pub Date : 2024-03-11 DOI: 10.1021/acs.chas.4c00018

Cheryl MacKenzie*,

引用次数: 0

Development of Safety Science and Engineering Disciplines in Mainland China 中国大陆安全科学与工程学科的发展

Journal of chemical health & safety Pub Date : 2024-03-07 DOI: 10.1021/acs.chas.3c00113

Jianfeng Yang, Feilong Zhang, Jianwen Zhang, Pengchao Wang, Siyu Peng, Qianlin Wang, Jinghai Li, Liangchao Chen and Zhan Dou*,

{"title":"Development of Safety Science and Engineering Disciplines in Mainland China","authors":"Jianfeng Yang, Feilong Zhang, Jianwen Zhang, Pengchao Wang, Siyu Peng, Qianlin Wang, Jinghai Li, Liangchao Chen and Zhan Dou*, ","doi":"10.1021/acs.chas.3c00113","DOIUrl":"10.1021/acs.chas.3c00113","url":null,"abstract":"Considering the growing emphasis on safety issues in mainland China, it is essential to identify the hurdles in the development of safety disciplines and to promote alignment between safety disciplines and society. To understand the current state of safety science and engineering disciplines in mainland China, we conducted a study while considering the geographical distribution level, as well as the power gap between universities. In terms of the geographical distribution, the spatial distribution characteristics of institutions with safety engineering enrollment in China were mapped out. To illustrate the development characteristics and existing safety discipline problems, the current situation of economic development and safety production in each region was integrated. In terms of power gaps, the Cingta database was used to study the disparity between different indicators and the competitiveness of safety disciplines in representative universities. Based on these findings, the development of chemical safety education is further discussed. Finally, development directions were provided for the effective reform of safety disciplines in each university at this stage. The study demonstrated that the current development status of safety disciplines in universities was related to social needs and social background. The development of safety disciplines in certain provinces of China did not match the current state of the local economy and safety products. There was a significant gap between the strengths and weaknesses of disciplines between universities and colleges.","PeriodicalId":73648,"journal":{"name":"Journal of chemical health & safety","volume":"31 3","pages":"238–252"},"PeriodicalIF":0.0,"publicationDate":"2024-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140070250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chemical Health Risk Assessment and Evaluation of Risk toward Ototoxicants among Workers at Palm Oil Mills 棕榈油厂工人的化学健康风险评估和耳毒性风险评价

Journal of chemical health & safety Pub Date : 2024-03-05 DOI: 10.1021/acs.chas.3c00090

Nornadiah Roslan, and , Mohamad Syazarudin Md Said*,

{"title":"Chemical Health Risk Assessment and Evaluation of Risk toward Ototoxicants among Workers at Palm Oil Mills","authors":"Nornadiah Roslan,  and , Mohamad Syazarudin Md Said*, ","doi":"10.1021/acs.chas.3c00090","DOIUrl":"10.1021/acs.chas.3c00090","url":null,"abstract":"Chemical and noise hazards are known to have a synergistic effect, where a variety of different chemical substances may worsen hearing damage in humans. These chemical substances are identified as ototoxicants that are toxic to the auditory system. This study evaluated the issue and created a framework in which these ototoxicants can be recognized early in the workplace. The approach involved hazard identification of chemicals hazardous to health, observation of tasks related to chemicals, identification of ototoxicants and noise exposure, evaluation of risks, and determination of the adequacy of control measures in accordance with the DOSH Malaysia Chemical Health Risk Assessment (CHRA) Third Edition Manual 2017 and the Industry Code of Practice for Management of Occupational Noise Exposure and Hearing Conservation 2019. The target subjects of this study involved 148 palm oil mill workers at two different locations who are exposed to both chemicals and noise throughout their daily tasks. Four work units (i.e., boiler operators and welders at palm oil mill A and laboratory analysts and welders at palm oil mill B) were concluded to have a significant risk of exposure to ototoxicants due to the high noise exposure, inadequacy of engineering control, and unsuitable use of PPE.","PeriodicalId":73648,"journal":{"name":"Journal of chemical health & safety","volume":"31 3","pages":"202–216"},"PeriodicalIF":0.0,"publicationDate":"2024-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140047170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0