Journal of chemical health & safety最新文献

{"title":"Unveiling the Biphasic Impacts of Naringenin on Organismal and Suborganismal Levels in Drosophila melanogaster","authors":"Siddhartha Ghanty,&nbsp;Abhratanu Ganguly,&nbsp;Sayantani Nanda,&nbsp;Moutushi Mandi,&nbsp;Kanchana Das,&nbsp;Gopal Biswas,&nbsp;Pritam Maitra,&nbsp;Nurunnisa Khatun and Prem Rajak*,&nbsp;","doi":"10.1021/acs.chas.4c0014910.1021/acs.chas.4c00149","DOIUrl":"https://doi.org/10.1021/acs.chas.4c00149https://doi.org/10.1021/acs.chas.4c00149","url":null,"abstract":"<p >Naringenin is a phenolic compound of the flavanone class found in many citrus fruits. It has several health benefits. However, its impacts may vary based on the concentration or dose. Hence, the purpose of the present study was to investigate the concentration-dependent impacts of naringenin on an <i>in vivo</i> model, <i>Drosophila melanogaster</i>. For this study, first-instar larvae were exposed to graded concentrations of naringenin until their third-instar or adult stage. Treated larvae were dissected to expose the visceral organs such as the brain, fat body, and gut to examine cytotoxicity. Moreover, ROS production and lipid droplet deposition were analyzed in the alimentary tract. The impact of graded concentrations of naringenin on life cycle parameters and longevity was further investigated. Results showed a biphasic impact of naringenin, where naringenin at lower concentrations (300–500 μM) exhibited its antioxidant effects by scavenging the ROS and improving the longevity of flies. Nonetheless, higher concentrations of naringenin caused excess ROS accumulation and lipid deposition in tissues of the digestive tract of treated individuals. Higher concentrations of naringenin (700 and 800 μM) were also responsible for the marked reduction in longevity and alteration in developmental duration of <i>D. melanogaster</i>. All of these results equivocally suggest that naringenin at low concentrations has health-promoting effects. However, the health benefits of this phenolic compound can be reversed at higher concentrations in <i>D. melanogaster</i>, triggering potential health concerns for humans. Therefore, it is recommended that the dose or concentration of naringenin should be standardized for its safe use.</p>","PeriodicalId":73648,"journal":{"name":"Journal of chemical health & safety","volume":"32 2","pages":"194–203 194–203"},"PeriodicalIF":0.0,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143675862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to \"Nature-Derived Flame Retardant for Cotton Fabric with Green Coconut Shell\".","authors":"Tarikul Islam, Abdullah Al Rakib Shikder, Md Shahabul Hossen, Md Mazbah Uddin, Md Tanvir Hossain, M Mahbubul Bashar","doi":"10.1021/acs.chas.5c00030","DOIUrl":"https://doi.org/10.1021/acs.chas.5c00030","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1021/acs.chas.4c00050.].</p>","PeriodicalId":73648,"journal":{"name":"Journal of chemical health & safety","volume":"32 2","pages":"204"},"PeriodicalIF":0.0,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11938338/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143733510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to “Nature-Derived Flame Retardant for Cotton Fabric with Green Coconut Shell”","authors":"Tarikul Islam*,&nbsp;Abdullah Al Rakib Shikder,&nbsp;Md. Shahabul Hossen,&nbsp;Md Mazbah Uddin,&nbsp;Md Tanvir Hossain and M Mahbubul Bashar*,&nbsp;","doi":"10.1021/acs.chas.5c0003010.1021/acs.chas.5c00030","DOIUrl":"https://doi.org/10.1021/acs.chas.5c00030https://doi.org/10.1021/acs.chas.5c00030","url":null,"abstract":"","PeriodicalId":73648,"journal":{"name":"Journal of chemical health & safety","volume":"32 2","pages":"204 204"},"PeriodicalIF":0.0,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acs.chas.5c00030","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143675830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison on Thermal Runaway and Critical Characteristics of Cylindrical Lithium-Ion Batteries: A Review","authors":"Wei Li,&nbsp;Jiasheng Wang,&nbsp;Chunfeng Sun,&nbsp;Xiaoping Fan,&nbsp;Lingzhu Gong*,&nbsp;Jiale Huang*,&nbsp;Jian-heng Wu,&nbsp;Gending Yu,&nbsp;Rongguo Chen,&nbsp;Jingling Li and Yih-Shing Duh*,&nbsp;","doi":"10.1021/acs.chas.4c0012110.1021/acs.chas.4c00121","DOIUrl":"https://doi.org/10.1021/acs.chas.4c00121https://doi.org/10.1021/acs.chas.4c00121","url":null,"abstract":"<p >The thermal hazard results of commercial cylindrical lithium-ion batteries (LIBs) of different sizes from international laboratories are reviewed and discussed. The four types discussed encompass 14500, 18650, 21700, and 26650 ones. Characteristic data from the calorimeter include onset temperature, critical temperature, maximum temperature, maximum self-heat rate, enthalpy change, and quantity of noncondensable gases. By integrating thermal hazard data, a box-plot was established and hazard ranking was clearly evaluated as 21700 &gt; 18650 non-LiFePO₄ (LFP) ≫ 26650 LFP &gt; 14500 non-LFP &gt; 18650 LFP &gt; 14500 LFP. Among all types of cylindrical lithium-ion batteries, the 21700 exhibits the worst consequence, which is attributed to the adoption of high energy density LiNi_0.8Co_0.15Al_0.05O₂ (NCA) and LiNi_<i>x</i>Mn_<i>y</i>Co_<i>z</i>O₂ (NMC) cathode materials. It was found that the critical temperature <i>T</i>_cr and maximum temperature broadly scattered; besides, most of the maximum self-heat rate (d<i>T</i>/d<i>t</i>) and pressure data were absent in literature. Definitions of onset temperature, critical temperature, trigger temperature, and possible heat sources to stimulate the severe thermal runaway were collected and found to be unimaginably divergent. A thermal analysis database was established to classify critical temperatures into high <i>T</i>_cr (above 180 °C), low <i>T</i>_cr (130–180 °C), and no <i>T</i>_cr. The low <i>T</i>_cr inducement is speculated to be caused by gas shock or electron breakdown after the separator melted, while the intrinsic characteristics of <i>T</i>_cr require further investigation. Thermal runaway features of cylindrical LIBs can be concisely classified as lowest <i>T</i>_onset of 88.0 °C (21700 NMC) vs highest <i>T</i>_onset of 220.0 °C (18650 LFP), highest (d<i>T</i>/d<i>t</i>)_max of 64536.0 °C min^–1 (21700 NCA) vs lowest (d<i>T</i>/d<i>t</i>)_max of 3.0 °C min^–1 (18650 LFP), highest <i>T</i>_max of 1257.9 °C (21700 NCA) vs lowest <i>T</i>_max of 243.2 °C (18650 LFP), highest Δ<i>n</i> of 314.0 mmol (18650 NCA) vs lowest Δ<i>n</i> of 23.3 mmol (14500 LFP), lowest <i>T</i>_cr of 145.5 °C (21700 NCA) vs (no <i>T</i>_cr) (14500 and 18650 LFP), and highest Δ<i>H</i> of 70.5 kJ (21700 NCA) vs lowest Δ<i>H</i> of 0.8 kJ (14500 LFP). In this work, the present research is reviewed in detail and future perspectives are proposed. This review on the critical characteristics of cylindrical batteries under thermal failure and thermal abuse provides a reference for solving intrinsic safety issues for lithium-ion batteries of the next generation.</p>","PeriodicalId":73648,"journal":{"name":"Journal of chemical health & safety","volume":"32 2","pages":"133–156 133–156"},"PeriodicalIF":0.0,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143675882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Gist of the List","authors":"Lauren Goulding*,&nbsp;","doi":"10.1021/acs.chas.5c0003210.1021/acs.chas.5c00032","DOIUrl":"https://doi.org/10.1021/acs.chas.5c00032https://doi.org/10.1021/acs.chas.5c00032","url":null,"abstract":"","PeriodicalId":73648,"journal":{"name":"Journal of chemical health & safety","volume":"32 2","pages":"124–125 124–125"},"PeriodicalIF":0.0,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143675886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beyond the Visual: Achieving Accessibility in Scientific Figures","authors":"Hannah Ramsey*,&nbsp; and ,&nbsp;Imke Schröder,&nbsp;","doi":"10.1021/acs.chas.4c0014110.1021/acs.chas.4c00141","DOIUrl":"https://doi.org/10.1021/acs.chas.4c00141https://doi.org/10.1021/acs.chas.4c00141","url":null,"abstract":"<p >Scientific figures are essential tools for conveying complex research data, yet their accessibility issues can exclude individuals with disabilities, limiting the reach and impact of scientific publications. This Commentary explores strategies for enhancing figure accessibility in accordance with the Web Content Accessibility Guidelines (WCAG) 2.1 AA, which will become a legal standard for public agencies in April of 2026. Approximately 5% of U.S. adults have some form of visual impairment, underscoring the importance of inclusive design. Key recommendations include ensuring sufficient color contrast (minimum ratios of 3:1 or 4.5:1 depending on text size), using structural elements like patterns or shapes to differentiate data for colorblind readers, optimizing font styles and sizes for readability, and providing concise, descriptive alternative text for screen readers. These practices not only accommodate individuals with permanent or temporary limitations but also improve the overall usability and comprehension of figures for all readers, fostering broader engagement and equitable access to scientific knowledge.</p>","PeriodicalId":73648,"journal":{"name":"Journal of chemical health & safety","volume":"32 2","pages":"126–132 126–132"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acs.chas.4c00141","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143675857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Volatile Organic Chemical Emissions from Standard and “Eco” Resins for Vat Photopolymerization Additive Manufacturing (“3D”) Printers and Potential Mitigation Strategies","authors":"Justin P. Miller-Schulze*,&nbsp; and ,&nbsp;Nicholas D. Williams,&nbsp;","doi":"10.1021/acs.chas.4c0008710.1021/acs.chas.4c00087","DOIUrl":"https://doi.org/10.1021/acs.chas.4c00087https://doi.org/10.1021/acs.chas.4c00087","url":null,"abstract":"<p >The chemical profile and magnitude of emissions from vat photopolymerization (VP) 3D printers, in which a liquid resin cures into a solid upon exposure to ultraviolet light, are understudied. Here, six Volatile Organic Chemicals (VOCs) were identified in emissions from an entry-level VP printer using both Standard and “Eco” resin formulations and quantified in four phases of the VP printing process. To the best of our knowledge, this work is the first to assess emissions of “Eco” resins. Two shapes were printed to assess the impact of the surface area on emissions. Emissions were greatest for two monomers, 2-hydroxyethyl acrylate and 4-acrylomorpholine. Mesitaldehyde, tolylene-2,4-diisocyanate, 2,6-di-<i>tert</i>-butyl-p-cresol, and dipropylene glycol diacrylate emissions were more consistent. Generally, Standard resin emissions exceeded Eco resin emissions. Object surface area did not have a clear impact on emissions. Similar or higher emissions from idle printers with an uncovered resin vat compared to emissions from active printing were observed. For the first time, it was demonstrated that idle printer emissions were reduced drastically (by 70–97%) using a fabricated vat lid, demonstrating the importance of a sealed resin vat to reduce VOC emissions. Where available, reference exposure limits for the VOCs measured were compared with total emissions; this analysis indicated that these emission rates lead to exposures approaching or exceeding available exposure thresholds. These results show that a simple mitigation strategy and, to a lesser extent, the use of a low-VOC resin should lower the emissions of VP printers and, as such, reduce VOC exposures for the users of VP Printers.</p>","PeriodicalId":73648,"journal":{"name":"Journal of chemical health & safety","volume":"32 2","pages":"175–185 175–185"},"PeriodicalIF":0.0,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acs.chas.4c00087","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143675705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retraction of “Flame Retardant and Anticorrosion Behavior of Multifunctional Epoxy Nanocomposite Coatings Containing Graphitic Carbon Nitride/Silanized HfO2 Nanofillers for the Protection of Steel Surface in Automobile Industry”","authors":"Joseph Raj Xavier*,&nbsp;Vinodhini S P,&nbsp;Ramesh B and Raja Beryl J,&nbsp;","doi":"10.1021/acs.chas.5c0001910.1021/acs.chas.5c00019","DOIUrl":"https://doi.org/10.1021/acs.chas.5c00019https://doi.org/10.1021/acs.chas.5c00019","url":null,"abstract":"","PeriodicalId":73648,"journal":{"name":"Journal of chemical health & safety","volume":"32 2","pages":"205 205"},"PeriodicalIF":0.0,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143675732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ecotoxicity of Entecavir in Aliivibrio fischeri, Microcystis novacekii, Artemia salina, and Biomphalaria glabrata","authors":"Cléssius R. de Souza*,&nbsp;Gabriel Souza-Silva,&nbsp;Fernanda V. M. Silva,&nbsp;Paula von R. Cardoso,&nbsp;Maria Clara V. M. Starling,&nbsp;Walter S. Lima,&nbsp;Cíntia A. J. Pereira,&nbsp;Marcos P. G. Mol and Micheline R. Silveira,&nbsp;","doi":"10.1021/acs.chas.4c0008410.1021/acs.chas.4c00084","DOIUrl":"https://doi.org/10.1021/acs.chas.4c00084https://doi.org/10.1021/acs.chas.4c00084","url":null,"abstract":"<p >The worldwide consumption of medicines has increased exponentially with a consequent increase of these pollutants in the environment. This study aimed to evaluate the ecotoxicity of entecavir (ETV), an antiviral used to treat hepatitis B, in models of <i>Aliivibrio fischeri</i>, <i>Microcystis novacekii</i>, <i>Artemia salina</i>, and <i>Biomphalaria glabrata</i>, which directly interferes with enzymatic processes and protein synthesis, possibly impacting the environment and human health. In the ecotoxicological tests, the organisms were exposed to ETV concentrations ranging from 0 to 300 mg/L at 30 min to 96 h intervals, depending on the model used. Only toxicity results at concentrations below 100 mg/L were considered environmentally relevant. Statistical analyses for the <i>A. salina</i>, <i>M. novacekii</i>, and <i>B. glabrata</i> models were conducted using dose–response regressions. Mortality in the <i>B. glabrata</i> model was assessed using the Kruskal–Wallis test. For the model with <i>A. fischeri</i>, the analyses were performed considering the mean bioluminescence values against the control (sample without ETV) on a logarithmic scale with the <i>R</i>² determination index as the reference for the fit under the standard Microtox procedure. A significance level of 5% was adopted for all analyses. None of the biological models exposed to ETV showed toxicity at environmentally relevant concentrations (&lt;100 mg/L). Although it may seem that ETV does not pose a risk to the environment due to its low ecotoxicological spectrum, given the lack of toxicity observed in the models tested and the nondetection of ETV in the environment, the rational use, disposal, treatment, and final disposal of pharmaceutical waste of this drug, the monitoring of pharmaceutical waste in sewage and water treatment systems and the improvement of these systems should be encouraged to mitigate possible environmental, economic, and health impacts.</p>","PeriodicalId":73648,"journal":{"name":"Journal of chemical health & safety","volume":"32 2","pages":"165–174 165–174"},"PeriodicalIF":0.0,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acs.chas.4c00084","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143675730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of Safety-Related Incidents Reported at a Major North American Petrochemical Processing Facility between 2016 and 2020","authors":"A. Dana Ménard*,&nbsp; and ,&nbsp;John F. Trant*,&nbsp;","doi":"10.1021/acs.chas.4c0012010.1021/acs.chas.4c00120","DOIUrl":"https://doi.org/10.1021/acs.chas.4c00120https://doi.org/10.1021/acs.chas.4c00120","url":null,"abstract":"<p >Chemistry is a potentially dangerous enterprise. Major incidents in academic and industrial settings are commonly used in the form of case studies to suggest lessons and inspire change; however, a truism of safety studies is that major incidents often arise from the same causes as those that previously caused minor events that remained unaddressed. However, major events make up only a very small percentage of the events that could, with multiple failures, lead to the adverse outcomes. In this study, we examined 258 routine safety incidents reported between 2016 and 2020 at a major petrochemical processing facility site in North America. Restricting the analysis to incidents that included both chemicals and human error reduced the sample to 75 incidents that were categorized via quantitative content analysis. Findings showed a significant effect of day of the week; most incidents involved mid-operation errors and related to administrative issues. Findings highlight a culture of reporting even superficially minor incidents, which may lead to improved safety-implementation policies that could help prevent major incidents from occurring. We propose a crude measure to determine the rigor of a reporting culture: the incident severity reporting threshold index, the ratio between the number of incidents involving injuries, and the total number of reported incidents. We strongly suggest that the severity threshold for reporting be lowered so as to address hazards and emergent risks before they have an opportunity to become dangerous. The implications of incident reporting and safety in industry are considered in relation to academic settings.</p>","PeriodicalId":73648,"journal":{"name":"Journal of chemical health & safety","volume":"32 2","pages":"186–193 186–193"},"PeriodicalIF":0.0,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143675729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}