Journal of chemical health & safety最新文献_第2页

Graduate Students’ Tolerance of Habitual Risk-Taking Behaviors in Chemical-Related Majors: A Case Study

Journal of chemical health & safety Pub Date : 2024-12-06 DOI: 10.1021/acs.chas.4c0006110.1021/acs.chas.4c00061

Haiqing Zhang, Xiaoyan Wang*, Xiaoyi Zhai, Yong Liu and Xinglong Jin,

引用次数: 0

Investigative Analysis of Safety Risk Assessment at a Science and Technology University: Step-by-Step Analysis with Accident Reports for Future Prevention

Journal of chemical health & safety Pub Date : 2024-12-03 DOI: 10.1021/acs.chas.4c0004610.1021/acs.chas.4c00046

Hiroko Kato, Masako Iwasaki, Takayuki Sunazaki, Shinichi Daiten and Yukitoshi Takeshita*,

{"title":"Investigative Analysis of Safety Risk Assessment at a Science and Technology University: Step-by-Step Analysis with Accident Reports for Future Prevention","authors":"Hiroko Kato, Masako Iwasaki, Takayuki Sunazaki, Shinichi Daiten and Yukitoshi Takeshita*, ","doi":"10.1021/acs.chas.4c0004610.1021/acs.chas.4c00046","DOIUrl":"https://doi.org/10.1021/acs.chas.4c00046https://doi.org/10.1021/acs.chas.4c00046","url":null,"abstract":"Our university, Tokyo Institute of Technology, conducted safety and health risk assessments (RA). Previous research indicated that many hazards identified in RA are less likely to be the main causes of actual accidents, while those not identified in RA are more likely to be the main causes of actual accident. Particularly, notable cases not identified as hazards in RA and having more occurrences as actual causes were “glass” and “cutting tool”. Therefore, the objective of this study is to find out why these hazards have not been identified and what should be done to ensure fruitful RA implementation. Here, RA reports and accident reports of “glass” and “cutting tool” related work were intensively investigated. The findings demonstrated that in STEP 1, the “hazard identification” stage, the risk-assuming work should be much closer to the actual accident, that is, to increase the awareness of hazards in pre- and postexperimental work such as “force-applied” work, where previously a low proportion of assumptions had been made. In STEP 2, “risk estimation and assessment” stage, the following steps are required: assume the situation of damage caused by the risk-assumed work in a more concrete, rather than vague, manner, estimate and score the degree of damage at a higher level, determine the risk level as III or IV accordingly, and link this to the consideration and implementation of preventive measures. Lastly, in STEP 3, the “consideration of risk reduction measure and implementation” stage, countermeasures were to focus on worker-independent measures, such as the “intrinsic measure” and “engineering measure”.","PeriodicalId":73648,"journal":{"name":"Journal of chemical health & safety","volume":"32 1","pages":"48–56 48–56"},"PeriodicalIF":0.0,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acs.chas.4c00046","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143087434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Optimization of Neutralization Conditions and Comparative Study of Nerve Agents and Simulants Using a Reaction Calorimeter

Journal of chemical health & safety Pub Date : 2024-11-28 DOI: 10.1021/acs.chas.4c0007310.1021/acs.chas.4c00073

Hyunsuk Kim*, Kyoung Chan Lim and Jihyun Kwon,

{"title":"Optimization of Neutralization Conditions and Comparative Study of Nerve Agents and Simulants Using a Reaction Calorimeter","authors":"Hyunsuk Kim*, Kyoung Chan Lim and Jihyun Kwon, ","doi":"10.1021/acs.chas.4c0007310.1021/acs.chas.4c00073","DOIUrl":"https://doi.org/10.1021/acs.chas.4c00073https://doi.org/10.1021/acs.chas.4c00073","url":null,"abstract":"Studies on the safe disposal of nerve agents face limitations due to the restrictions and risks associated with their use. In this study, we optimized the neutralization conditions for nerve agents pinacolyl methylphosphonofluoridate (GD), ethyl dimethylphosphoroamidocyanate (GA), and ethyl N-2-diisopropylaminoethyl methylphosphonothiolate (VX), by conducting comparative neutralization reactions using simulants and a reaction calorimeter. The neutralization reactions of diethyl chlorophosphite (DECP), diphenyl chlorophosphite (DPCP), and butyryl chloride (BC) were compared using a reaction calorimeter. More than 2 equiv of KOH neutralized over 99% of the nerve agents. To prevent the formation of precipitates and make the process suitable for the disposal of nerve agents, the reaction was conducted at concentrations of ≤40% for GD and GA and ≤60% for VX. The neutralization enthalpy of each agent was determined based on the measured heat flow; similar heat flow patterns were observed for GD, GA, DECP, and BC.","PeriodicalId":73648,"journal":{"name":"Journal of chemical health & safety","volume":"32 1","pages":"87–96 87–96"},"PeriodicalIF":0.0,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143091651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigating Risk Preference and Its Effect on the Laboratory Safety Attitude of First-Year Graduate Students

Journal of chemical health & safety Pub Date : 2024-11-20 DOI: 10.1021/acs.chas.4c0006510.1021/acs.chas.4c00065

Haiqing Zhang, Xiaoyi Zhai, Xiaoyan Wang* and Xinglong Jin*,

引用次数: 0

Dietary Rutin Mitigates High-Sucrose Diet-Induced Organismal, Cellular, and Biochemical Hazards in Drosophila melanogaster

Journal of chemical health & safety Pub Date : 2024-11-19 DOI: 10.1021/acs.chas.4c0008310.1021/acs.chas.4c00083

Abhratanu Ganguly, Sayantani Nanda, Moutushi Mandi, Kanchana Das, Gopal Biswas, Pritam Maitra and Prem Rajak*,

{"title":"Dietary Rutin Mitigates High-Sucrose Diet-Induced Organismal, Cellular, and Biochemical Hazards in Drosophila melanogaster","authors":"Abhratanu Ganguly, Sayantani Nanda, Moutushi Mandi, Kanchana Das, Gopal Biswas, Pritam Maitra and Prem Rajak*, ","doi":"10.1021/acs.chas.4c0008310.1021/acs.chas.4c00083","DOIUrl":"https://doi.org/10.1021/acs.chas.4c00083https://doi.org/10.1021/acs.chas.4c00083","url":null,"abstract":"Sucrose is an important ingredient in numerous food items across the globe. However, long-term exposure to a High-Sucrose Diet (HSD) can fuel several health issues. Hence, it is essential to investigate therapeutic agents that could be effective in minimizing HSD-induced adverse effects. The present study aims to dissect the protective potential of a bioactive compound, rutin, against HSD-mediated effects on the behavioral, cellular, and biochemical parameters of a model organism, Drosophila melanogaster. For the study, first instar larvae were exposed to various treatment foods containing 30% HSD alone and in combination with graded concentrations of rutin (100–300 μM). In results, exposure to HSD enhanced the free glucose content and cytotoxicity in treated larvae. Growth and development were apparently disturbed in HSD-fed individuals. Moreover, chronic exposure to HSD was associated with altered embedding behavior and photosensitivity. The study was extended to the biochemical level, where treatment with HSD enhanced free iron contents and Reactive Oxygen Species (ROS) production that indicated activation of the Fenton reaction in the subcellular environment. In addition, HSD declined the activities of metabolic enzymes, viz., glucose 6-phosphate dehydrogenase, malate dehydrogenase, and angiotensin-converting enzyme. Interestingly, cotreatment with 150, 200, and 250 μM rutin significantly lessened HSD-mediated adverse effects on organismal, behavioral, cellular, and biochemical features of D. melanogaster.","PeriodicalId":73648,"journal":{"name":"Journal of chemical health & safety","volume":"32 1","pages":"97–114 97–114"},"PeriodicalIF":0.0,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143091782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Study on the Deflagration Characteristics and Application of Portable Gas Pulse Ash Cleaning Devices

Journal of chemical health & safety Pub Date : 2024-11-19 DOI: 10.1021/acs.chas.4c0005910.1021/acs.chas.4c00059

Jing Zhao, Xiaolin Wei*, Feng Bin, Bo Li, Teng Li, Sen Li, Heng Cheng and Qingqing Chen,

{"title":"Study on the Deflagration Characteristics and Application of Portable Gas Pulse Ash Cleaning Devices","authors":"Jing Zhao, Xiaolin Wei*, Feng Bin, Bo Li, Teng Li, Sen Li, Heng Cheng and Qingqing Chen, ","doi":"10.1021/acs.chas.4c0005910.1021/acs.chas.4c00059","DOIUrl":"https://doi.org/10.1021/acs.chas.4c00059https://doi.org/10.1021/acs.chas.4c00059","url":null,"abstract":"There is a common problem of ash accumulation in the heat exchange tubes of large boilers, which can decrease the efficiency of heat exchangers, increase system resistance, and cause corrosion, easily leading to heat exchange tube explosions. It is necessary to develop efficient and low-cost methods for ash cleaning to ensure the safe and efficient operation of boilers. This paper presents a study on the deflagration characteristics of portable gas pulse ash cleaning devices, and the ash cleaning effect of these devices was also verified in actual waste incineration plants. The experimental results indicate that the transfer characteristics of deflagration pressure waves are influenced by the fuel type, equivalence ratio, initial inflation pressure of the premixed gas, and mixture container size; among them, C2H2 has the best deflagration performance and is suitable for use as the preferred fuel for this technology, and the equivalence ratio of the highest deflagration intensity is approximately 0.9. Meanwhile, the deflagration pressure waves can also be enhanced by increasing the initial inflation pressure and selecting a thinner diaphragm. The portable gas pulse ash cleaning device can reduce the emitted gas temperature of waste heat boilers by approximately 30 °C after application verification. The main advantages of the device are its high efficiency of ash removal, simple operation, low equipment investment, and low operation cost, and it has broad application prospects in the ash cleaning of waste heat boilers.","PeriodicalId":73648,"journal":{"name":"Journal of chemical health & safety","volume":"32 1","pages":"66–74 66–74"},"PeriodicalIF":0.0,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143091784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Addition to “Chemical Safety: TATP Formation in 2-Propanol”

Journal of chemical health & safety Pub Date : 2024-11-15 DOI: 10.1021/acs.chas.4c0008910.1021/acs.chas.4c00089

Cory Christopher Pye*,

引用次数: 0

The Gist of the List 清单要点

Journal of chemical health & safety Pub Date : 2024-11-08 DOI: 10.1021/acs.chas.4c0011210.1021/acs.chas.4c00112

Lauren Goulding*,

引用次数: 0

Critical Review of Biomedical Waste Management for Future Pandemics: Pharmaceutical Perspective 针对未来大流行病的生物医学废物管理批判性评论：制药业视角

Journal of chemical health & safety Pub Date : 2024-11-01 DOI: 10.1021/acs.chas.4c0006710.1021/acs.chas.4c00067

Saloni Agarwal, Hiranmoy Saha, Swati Kaushik, Vaishali M. Patil and Saroj Verma*,

{"title":"Critical Review of Biomedical Waste Management for Future Pandemics: Pharmaceutical Perspective","authors":"Saloni Agarwal, Hiranmoy Saha, Swati Kaushik, Vaishali M. Patil and Saroj Verma*, ","doi":"10.1021/acs.chas.4c0006710.1021/acs.chas.4c00067","DOIUrl":"https://doi.org/10.1021/acs.chas.4c00067https://doi.org/10.1021/acs.chas.4c00067","url":null,"abstract":"During the pandemic, biomedical waste (BMW) management was reported as a global problem. World Health Organization has also stressed that COVID-19 resulted in the production of tens of thousands of tons of BMW. It includes waste from hospitals, research laboratories, pharmaceutical industry, etc., and among them, pharmaceutical waste has a major effect on the ecosystem. It includes waste generated during diagnosis, research activities, immunization, and treatment, such as vials, bottles, gloves, masks, needles, expired/unused/spilled/contaminated drugs, radioactive material, pharmacological waste, etc. Timely and precise management of BMW is a vital issue, and the present manuscript aims to provide a comprehensive overview of BMW with a major focus on pharmaceutical waste, their types, points of entry, and its management using pyrolysis, nanotechnologies, etc. Available guidelines and challenges associated with the management technologies have been reviewed, and we have proposed a practical framework suggesting the role of government agencies and the pharmaceutical industry and expected outcomes from the suggested techniques in stepwise manner. Besides various developments in the pharmaceutical field, there is requirement to develop and implement environmentally friendly approaches for BMW disposal to benefit the community.","PeriodicalId":73648,"journal":{"name":"Journal of chemical health & safety","volume":"31 6","pages":"444–467 444–467"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142694452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Disaster Resource Management 灾害资源管理

Journal of chemical health & safety Pub Date : 2024-10-28 DOI: 10.1021/acs.chas.4c0009910.1021/acs.chas.4c00099

Ya-Fan Lin, Yi-Hsin Liu* and Fun Man Fung*,

引用次数: 0