{"title":"New Trends Approved in Management of Dyslipidaemia","authors":"Abdulaziz Aboshahba","doi":"10.19080/jocct.2019.14.555894","DOIUrl":"https://doi.org/10.19080/jocct.2019.14.555894","url":null,"abstract":"Hypercholesterolemia increases the risk of atherosclerotic cardiovascular disease and is incompletely reversed by statin therapy alone in many patients. Familial hypercholesterolemia (FH) is a common genetic cause of premature cardiovascular disease (CVD). So, most of efforts and directions focused on new therapies as PCSK9 gene was identified in the past decade as a potential therapeutic target for the management of patients with hypercholesterolemia which monoclonal antibodies, Lomitapide, Mipomersen and other therapies hoping to reduce risk of hypercholesterolemia. The novel therapies are aiming for better lipid-lowering effects, fewer side effects and improved clinical outcomes.","PeriodicalId":73635,"journal":{"name":"Journal of cardiology & cardiovascular therapy","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48941504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Unilateral Chronic Thromboembolic Pulmonary Hypertension - A Case Report of Unusual Presentation of CTEPH","authors":"N. Jain","doi":"10.19080/jocct.2019.14.555892","DOIUrl":"https://doi.org/10.19080/jocct.2019.14.555892","url":null,"abstract":"Chronic thromboembolic pulmonary hypertension categorized as group IV pulmonary according to World Health Organization, is defined as mean pulmonary arterial pressure of more than 25 mm Hg that persists inspite of more than 6 months of anticoagulation in presence of persistent pulmonary thrombi. Chronic thromboembolic pulmonary hypertension is an uncommon and potentially fatal sequelae of acute pulmonary embolism. It is usually diagnosed in late stage due to lack of early diagnosis and carry poor prognosis if definitive treatment is not given. As compared to other categories of pulmonary hypertension, chronic thromboembolic hypertension is potentially curable with pulmonary endarterectomy. The usual presentation is bilateral pulmonary artery involvement. We describe an unusual presentation of unilateral pulmonary artery involvement in a patient with Factor V Leiden mutation. Patient was successfully treated with pulmonary endarterectomy.","PeriodicalId":73635,"journal":{"name":"Journal of cardiology & cardiovascular therapy","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45091770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Valve-in-Valve Transcatheter Aortic Valve Implantation of an Evolut R in a Degenerated Lotus Valve","authors":"L. Conzelmann","doi":"10.19080/jocct.2019.14.555893","DOIUrl":"https://doi.org/10.19080/jocct.2019.14.555893","url":null,"abstract":"Degeneration of bioprosthesis also occurs in transcatheter aortic valve implantation. Treatment option in severe bioprosthetic failure is either surgical aortic valve replacement or transcatheter valve-in-valve implantation. Information about feasibility and outcome of the latter interventions is sparse. was to an A gradient of 27/18mmHg was measured at discharge. she represented with Echocardiography revealed a degenerated TAVI-bioprosthesis with an orifice area of 0.8cm² and a Pmax/mean of 90/50mmHg. to the restricted condition and comorbidities of this patient (logistic EuroSCORE I 32.75%) a valve-in-valve procedure was discussed. Meticulous planning including coronary angiography and CT-scan revealed an inner valve diameter of 18mm, a height of 20mm,","PeriodicalId":73635,"journal":{"name":"Journal of cardiology & cardiovascular therapy","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46463901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Giant Ascending Aortic Aneurysm Presented with Acute Onset Superior Vena Cava Syndrome","authors":"J. Alcocer","doi":"10.19080/jocct.2019.14.555891","DOIUrl":"https://doi.org/10.19080/jocct.2019.14.555891","url":null,"abstract":"We present a case of a 50 year-old-male patient with past history of tissue aortic valve replacement presented at the emergency department with chest pain and acute onset superior vena cava syndrome. After physical examination and CT aortic angiogram a giant ascending aortic aneurysm complicated with aorta to superior vena cava fistula was identified. The patient underwent emergent surgery consisting of aortic root replacement with mechanical valveconduit and total arch replacement under hypothermic cardiopulmonary bypass. The patient had an uneventful postoperative recovery and was discharged at postoperative day 8. Postoperative CT aortic angiogram showed an excellent surgical result.","PeriodicalId":73635,"journal":{"name":"Journal of cardiology & cardiovascular therapy","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44136888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Anthocyanin intake and Arterial Stiffness: A Literature Review","authors":"A. Lehnen","doi":"10.19080/jocct.2019.14.555890","DOIUrl":"https://doi.org/10.19080/jocct.2019.14.555890","url":null,"abstract":"There is a well-established association between aging, arterial stiffness, endothelial dysfunction, oxidative stress and the ensuing increased cardiovascular risk. Agents with antioxidant activity can improve endothelial function and arterial stiffness. Açaí-juçara is a fruit rich in anthocyanins, which are powerful antioxidants, and its daily consumption may have beneficial effects on vascular health, especially on central pulse pressure and pulse wave velocity. As anthocyanins may improve vascular health, especially central pulse pressure, dietary intake of anthocyanin-rich foods may reduce cardiovascular risk. Thus, this study aimed to review the effects of dietary intake of anthocyanins and its potential associations with central blood pressure improvement in overweight and obese individuals.","PeriodicalId":73635,"journal":{"name":"Journal of cardiology & cardiovascular therapy","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46361186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cardiology One-Stop-Service Changing Approach to Improve Appropriateness","authors":"G. Gullace","doi":"10.19080/jocct.2019.14.555888","DOIUrl":"https://doi.org/10.19080/jocct.2019.14.555888","url":null,"abstract":"Health needs, prevention, the increase of survivors, defense medicine are main factors contributing to the increase of specialistic examinations and instrumental exams with the consequence of inappropriateness increase, organization not always able to give the right answers to the patients and increase of unsatisfaction and inconvenience in the patients. The proposal presented in this paper is based on Cardiologist and General Practitioner cooperation agreement that on one side proposes a problem-approach of specialistic consultation and on the other side the availability of the Cardiologist to take the responsibility of the patient’s pathway until it will be closed by a diagnosis or a therapeutical intervention. In this way, the offer for the patient is not the performed exams and its conclusion but the problem solution to his health need.","PeriodicalId":73635,"journal":{"name":"Journal of cardiology & cardiovascular therapy","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44083212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cardiorenal Syndrome Type I A-A Study of its Incidence, Risk Factors, Laboratory Parameters and Outcome","authors":"B. Abdullah","doi":"10.19080/jocct.2019.14.555887","DOIUrl":"https://doi.org/10.19080/jocct.2019.14.555887","url":null,"abstract":"The burden of HF in India appears high and Acute kidney injury is a leading cause of morbidity and mortality. The mechanisms underlying this interaction are complex and multifactorial in nature.","PeriodicalId":73635,"journal":{"name":"Journal of cardiology & cardiovascular therapy","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42599427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Heart Failure with Preserved Ejection Fraction: A Review for the Clinician","authors":"K. Fukamachi","doi":"10.19080/jocct.2019.14.555886","DOIUrl":"https://doi.org/10.19080/jocct.2019.14.555886","url":null,"abstract":"Almost half of patients with heart failure also have preserved ejection fraction (HFpEF) and the prevalence is increasing. HFpEF is diagnosed based on signs and symptoms of heart failure with ejection fraction of ≥50%. Patients with HFpEF are a heterogeneous group with multiple associated comorbid conditions, including obesity, female gender, advanced age, and hypertension. No clear treatment guidelines exist for HFpEF, and most therapies have not shown a clear benefit in lessening mortality. Current options include treating signs and symptoms and the associated comorbidities. Future therapeutic options have shown some promise; however, larger cohorts and more randomized controlled trials are needed.","PeriodicalId":73635,"journal":{"name":"Journal of cardiology & cardiovascular therapy","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44107676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Echocardiography in Different Clinical Situations Appropriate use to do Better","authors":"G. Gullace","doi":"10.19080/jocct.2019.14.555884","DOIUrl":"https://doi.org/10.19080/jocct.2019.14.555884","url":null,"abstract":"In the last 5 decades the utilization of ultrasound has greatly developed into echocardiography, generating a confused picture of the echocardiographic technique, with patients who do not always receive the right echocardiogram. Previous publications have reported a proposal for reclassification of Echocardiography based on function, competence, applications, proper machines and purposes is intended to give a coherent and adequate definition of requirements, in order to have appropriate use of the technique related to place where it is used, the clinical situation, the related function, the information expected, the exam indications and the educational pathway and requirements for the accreditation of the operators and echo-labs. In this paper we revisit these proposals emphasizing the importance to use echo properly and appropriately as well as the need to acquire accreditation through a defined educational pathway and training and the possibilities to use it widely in different clinical conditions.","PeriodicalId":73635,"journal":{"name":"Journal of cardiology & cardiovascular therapy","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46975693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}