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Journal of cardiology & cardiovascular therapy最新文献

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Heart Failure and Malignancy: Implications of Chemotherapy and Radiation in the Pathogenesis of Cardiomyopathy in Cancer Treated Populations. 心衰和恶性肿瘤:化疗和放疗在癌症治疗人群心肌病发病机制中的意义。
Journal of cardiology & cardiovascular therapy Pub Date : 2020-12-01
Perry Wengrofsky, Maya Srinivasan, Haytham Aboushi, Vaibhavi Solanki, Inna Bukharovich, Fadi Yacoub, Maria Poplawska, Samy I McFarlane
{"title":"Heart Failure and Malignancy: Implications of Chemotherapy and Radiation in the Pathogenesis of Cardiomyopathy in Cancer Treated Populations.","authors":"Perry Wengrofsky,&nbsp;Maya Srinivasan,&nbsp;Haytham Aboushi,&nbsp;Vaibhavi Solanki,&nbsp;Inna Bukharovich,&nbsp;Fadi Yacoub,&nbsp;Maria Poplawska,&nbsp;Samy I McFarlane","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The field of Cardio-oncology is rapidly growing with significant advances in research leading to better understanding of the underlying pathogenesis with implications in the diagnosis and management of cancer-related cardiomyopathy. Parallel to advancement in cardio-oncology is an increased awareness of the incidence of congestive heart failure and cardiomyopathy associated with malignancy. While specific cardiotoxic profiles exist for certain chemotherapeutic agents, there is increasing evidence of unexpected cardiotoxic side effects of some therapeutic modalities, combination chemo- and radiotherapy with large analyses identifying a strong association between malignancy and Takotsubo cardiomyopathy. Takotsubo Cardiomyopathy, also known as \"broken-heart\" syndrome or stress cardiomyopathy, is characterized by transient and reversible, regional or global, myocardial dysfunction without inciting ischemic perfusion defect from obstructive coronary artery disease. While direct causative pathophysiologic mechanisms continue to be investigated, much of the postulated pathways center on the high emotional and physical burdens of cancer and the related emotional stress associated with the diagnosis of cancer as well as the corporal effects of anti-neoplastic therapies, radiation, and oncologic surgery. In this manuscript we review the most current data in this rapidly emerging field highlighting the epidemiology, the postulated pathogenetic mechanisms as well as the current guidelines by major societies addressing malignancy -associated heart failure and cardiomyopathy, a rather complex disease entity with high morbidity and mortality.</p>","PeriodicalId":73635,"journal":{"name":"Journal of cardiology & cardiovascular therapy","volume":"16 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10545478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Heart Failure and Malignancy: Implications of Chemotherapy and Radiation in the Pathogenesis of Cardiomyopathy in Cancer Treated Populations 心力衰竭和恶性肿瘤：化疗和放疗在癌症治疗人群心肌疾病发病机制中的意义
Journal of cardiology & cardiovascular therapy Pub Date : 2020-12-01 DOI: 10.19080/jocct.2020.16.555944
Perry Wengrofsky, Maya Srinivasan, H. Aboushi, Vaibhavi Solanki, I. Bukharovich, Fadi Yacoub, Maria Poplawska, Samy I McFarlane
{"title":"Heart Failure and Malignancy: Implications of Chemotherapy and Radiation in the Pathogenesis of Cardiomyopathy in Cancer Treated Populations","authors":"Perry Wengrofsky, Maya Srinivasan, H. Aboushi, Vaibhavi Solanki, I. Bukharovich, Fadi Yacoub, Maria Poplawska, Samy I McFarlane","doi":"10.19080/jocct.2020.16.555944","DOIUrl":"https://doi.org/10.19080/jocct.2020.16.555944","url":null,"abstract":"The field of Cardio-oncology is rapidly growing with significant advances in research leading to better understanding of the underlying pathogenesis with implications in the diagnosis and management of cancer-related cardiomyopathy. Parallel to advancement in cardio-oncology is an increased awareness of the incidence of congestive heart failure and cardiomyopathy associated with malignancy. While specific cardiotoxic profiles exist for certain chemotherapeutic agents, there is increasing evidence of unexpected cardiotoxic side effects of some therapeutic modalities, combination chemo- and radiotherapy with large analyses identifying a strong association between malignancy and Takotsubo cardiomyopathy. Takotsubo Cardiomyopathy, also known as “broken-heart” syndrome or stress cardiomyopathy, is characterized by transient and reversible, regional or global, myocardial dysfunction without inciting ischemic perfusion defect from obstructive coronary artery disease. While direct causative pathophysiologic mechanisms continue to be investigated, much of the postulated pathways center on the high emotional and physical burdens of cancer and the related emotional stress associated with the diagnosis of cancer as well as the corporal effects of anti-neoplastic therapies, radiation, and oncologic surgery. In this manuscript we review the most current data in this rapidly emerging field highlighting the epidemiology, the postulated pathogenetic mechanisms as well as the current guidelines by major societies addressing malignancy -associated heart failure and cardiomyopathy, a rather complex disease entity with high morbidity and mortality.","PeriodicalId":73635,"journal":{"name":"Journal of cardiology & cardiovascular therapy","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45328187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Extracardiac Inappropriate Shocks in Subcutaneous Implantable Cardioverter Defibrillator: Management in Emergency Department 皮下植入式心脏复律除颤器的心外不适当电击：急诊科的处理
Journal of cardiology & cardiovascular therapy Pub Date : 2020-11-12 DOI: 10.19080/jocct.2020.16.555941
M. Santomauro
{"title":"Extracardiac Inappropriate Shocks in Subcutaneous Implantable Cardioverter Defibrillator: Management in Emergency Department","authors":"M. Santomauro","doi":"10.19080/jocct.2020.16.555941","DOIUrl":"https://doi.org/10.19080/jocct.2020.16.555941","url":null,"abstract":"The subcutaneous implantable cardioverter defibrillator (S-ICD) is an established treatment for the prevention of sudden cardiac death. In the S-ICD studies, inappropriate shocks (IAS) rate were reported to renge between 5% to 25% and to be mainly due to cardiac and noncardiac oversensing.","PeriodicalId":73635,"journal":{"name":"Journal of cardiology & cardiovascular therapy","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43454460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Is periodontitis associated with raised blood pressure or hypertension? Evidence from the National Health and Nutrition Examination Survey (NHANES), 2001-2002 牙周炎与血压升高或高血压有关吗?2001-2002年国家健康和营养检查调查(NHANES)的证据
Journal of cardiology & cardiovascular therapy Pub Date : 2020-10-14 DOI: 10.19080/jocct.2020.16.555940
Jing Guan
{"title":"Is periodontitis associated with raised blood pressure or hypertension? Evidence from the National Health and Nutrition Examination Survey (NHANES), 2001-2002","authors":"Jing Guan","doi":"10.19080/jocct.2020.16.555940","DOIUrl":"https://doi.org/10.19080/jocct.2020.16.555940","url":null,"abstract":"There is incomplete and inconclusive evidence for the correlation between periodontitis and blood pressure, particularly from large national epidemiological studies. The aim of this cross-sectional study was to assess the relationship between periodontitis and blood pressure and hypertension in people in USA, and to analyze confounding factors in both of them.","PeriodicalId":73635,"journal":{"name":"Journal of cardiology & cardiovascular therapy","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43284620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mechanical Cardiac Tamponade as an Initial Presentation of Malignant Lymphoma: Case Report 机械性心脏填塞术作为恶性淋巴瘤的初步表现：一例报告
Journal of cardiology & cardiovascular therapy Pub Date : 2020-08-14 DOI: 10.19080/jocct.2020.16.555938
M. Bouziane
{"title":"Mechanical Cardiac Tamponade as an Initial Presentation of Malignant Lymphoma: Case Report","authors":"M. Bouziane","doi":"10.19080/jocct.2020.16.555938","DOIUrl":"https://doi.org/10.19080/jocct.2020.16.555938","url":null,"abstract":"Cardiac tamponade results from an accumulation of pericardial fluid under pressure, leading to impaired cardiac filling and haemodynamic compromise. In malignant lymphoma, cardiac and pericardial involvement, even though relatively uncommon, can be one early manifestations of this neoplastic disease. We describe a case of a 21 year old female with no medical history, whose first presentation for mediastinal lymphoma was a mechanical cardiac tamponade.","PeriodicalId":73635,"journal":{"name":"Journal of cardiology & cardiovascular therapy","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44216871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
High Bioelectrical Impedance is Associated with High Blood Pressure Among US Adults - National Health and Nutrition Examination Survey, 2001 And 2002 高生物电阻抗与美国成年人高血压有关——2001年和2002年全国健康和营养调查
Journal of cardiology & cardiovascular therapy Pub Date : 2020-02-07 DOI: 10.19080/jocct.2020.15.555923
Chaofan Liu
{"title":"High Bioelectrical Impedance is Associated with High Blood Pressure Among US Adults - National Health and Nutrition Examination Survey, 2001 And 2002","authors":"Chaofan Liu","doi":"10.19080/jocct.2020.15.555923","DOIUrl":"https://doi.org/10.19080/jocct.2020.15.555923","url":null,"abstract":"","PeriodicalId":73635,"journal":{"name":"Journal of cardiology & cardiovascular therapy","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45073235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Severe Dilated Cardiomyopathy Due to Polycythemia Vera - A Rare Etiology 真性红细胞增多症引起的严重扩张性心肌病——一种罕见的病因
Journal of cardiology & cardiovascular therapy Pub Date : 2019-11-05 DOI: 10.19080/jocct.2019.15.555909
M. Butt
{"title":"Severe Dilated Cardiomyopathy Due to Polycythemia Vera - A Rare Etiology","authors":"M. Butt","doi":"10.19080/jocct.2019.15.555909","DOIUrl":"https://doi.org/10.19080/jocct.2019.15.555909","url":null,"abstract":"","PeriodicalId":73635,"journal":{"name":"Journal of cardiology & cardiovascular therapy","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44221300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Chronic Total Occlusion Treatment: Unraveling Intra-Stent Restenosis and Laser Atherectomy through Optical Coherence Tomography Imaging 慢性全闭塞治疗：通过光学相干断层扫描成像进行支架内再狭窄和激光动脉粥样硬化切除术
Journal of cardiology & cardiovascular therapy Pub Date : 2019-09-20 DOI: 10.19080/jocct.2019.15.555903
L. Dallan
{"title":"Chronic Total Occlusion Treatment: Unraveling Intra-Stent Restenosis and Laser Atherectomy through Optical Coherence Tomography Imaging","authors":"L. Dallan","doi":"10.19080/jocct.2019.15.555903","DOIUrl":"https://doi.org/10.19080/jocct.2019.15.555903","url":null,"abstract":"","PeriodicalId":73635,"journal":{"name":"Journal of cardiology & cardiovascular therapy","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48262904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Plasma Levels of SDF-1 are Acutely Correlated with Adrenergic Agonists and Modulated by β-Blockers Interactions in Hypertensive Individuals 高血压患者血浆中SDF-1水平与肾上腺素能激动剂密切相关，并受β-阻滞剂相互作用的调节
Journal of cardiology & cardiovascular therapy Pub Date : 2019-08-28 DOI: 10.19080/jocct.2019.14.555897
M. Markoski
{"title":"Plasma Levels of SDF-1 are Acutely Correlated with Adrenergic Agonists and Modulated by β-Blockers Interactions in Hypertensive Individuals","authors":"M. Markoski","doi":"10.19080/jocct.2019.14.555897","DOIUrl":"https://doi.org/10.19080/jocct.2019.14.555897","url":null,"abstract":"To examine the acute interference of β-blockers with plasma chemokine stromal cell-derived factor-1 (SDF-1), epinephrine and norepinephrine levels, as well as cardiovascular autonomic parameters.","PeriodicalId":73635,"journal":{"name":"Journal of cardiology & cardiovascular therapy","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46568972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pulmonary Hypertension and Neurofibromatosis Type 1: A Case Report with the Revision of Literature 肺动脉高压合并1型神经纤维瘤病1例并文献复习
Journal of cardiology & cardiovascular therapy Pub Date : 2019-08-27 DOI: 10.19080/jocct.2019.14.555896
W. Serra
{"title":"Pulmonary Hypertension and Neurofibromatosis Type 1: A Case Report with the Revision of Literature","authors":"W. Serra","doi":"10.19080/jocct.2019.14.555896","DOIUrl":"https://doi.org/10.19080/jocct.2019.14.555896","url":null,"abstract":"Neurofibromatosis Type 1 (NF1) is an autosomal dominant genetic disorder caused by mutations of the NF1 gene that can lead to the development of benign neurofibroma-like tumours and Malignant Peripheral Nerve Sheath Tumours (MPNST). Pulmonary Arterial Hypertension (PAH) is a rare but severe complication associated with NF1 (PAH-NF). PH-NF1 is classified as group 5 PH, defined as “PH with unclear and/or multifactorial mechanisms”, because the mechanisms of PH remain poorly understood. A better understanding of the genetic and molecular mechanisms underlying the disease may require new ways to develop specific therapies. We present the clinical outcomes of a 51-year old female previously diagnosed with NF1, who presented with progressively worsening dyspnea.","PeriodicalId":73635,"journal":{"name":"Journal of cardiology & cardiovascular therapy","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46350343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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