Jean-Marie Nguyen, Abdou Yacoubou Omorou, C. Rotonda, C. Tarquinio, S. Gendarme, C. Martin-Krumm, Aurélie Van Hoye
{"title":"Interaction between Physical Activity and Socioeconomic Determinants among Cancer Patients: A Systematic Mapping Review","authors":"Jean-Marie Nguyen, Abdou Yacoubou Omorou, C. Rotonda, C. Tarquinio, S. Gendarme, C. Martin-Krumm, Aurélie Van Hoye","doi":"10.26502/jcsct.5079132","DOIUrl":"https://doi.org/10.26502/jcsct.5079132","url":null,"abstract":"Socioeconomic factors and physical activity (PA), have been recognized as key factors affecting survival and quality of life of cancer patients. Nevertheless, less is known about their interactions among cancer patients. A mapping systematic review was undertaken to identify gaps in the literature regarding the interactions of socioeconomic factors and PA and the identification of theoretical model to define this relationship. A search for peer-reviewed English articles published between January 2010 and March 2020 in Medline, PsycINFO, Web of Science and SportDiscus databases was realized using three keywords: physical activity, cancer, socioeconomic. Cancer location and time, socioeconomic factor measurement, PA measurement, intervention and theoretical model were analyzed. Of the J Cancer Sci Clin Ther 2021; 5 (4): 468-495 DOI: 10.26502/jcsct.5079132 Journal of Cancer Science and Clinical Therapeutics 469 5163 articles found, 90 were included (86 observational studies and 4 interventions). While many studies evaluate socioeconomic factors and PA, authors often do not consider their interactions, but test them separately. Socioeconomic factors identified in the studies ranged among 12 categories (age, sex, ethnicity, education, income, occupation, residence, green space exposure, marital status, household, social support, Health insurance). A high diversity of measurements within each category led to a huge variation in the definition of socioeconomic factors and refrained comparison between studies. Similar conclusions could be drawn with regard to the diversity of PA measurements. Only few studies mobilized theoretical models, without considering the interactions between socioeconomic factors and PA. The definition of socioeconomic factors as well as theoretical modeling of how socioeconomic factors interact with PA among cancer patients needs to be clarified.","PeriodicalId":73634,"journal":{"name":"Journal of cancer science and clinical therapeutics","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69348094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Case of Using Wet Healing Theory for Wound Bed Preparation Care for A Patient with Breast Cancer Wounds","authors":"Wenli D, Yaping S, H. X, Ying Y","doi":"10.26502/jcsct.5079137","DOIUrl":"https://doi.org/10.26502/jcsct.5079137","url":null,"abstract":"Objective: To treat the breast cancer wound on the right breast surface by the theory of moist healing. Methods: According to the wound evaluation, appropriate dressing was used to keep the wound moist and promote the dissolution of necrosis. Results: Through dressing change, the wound was significantly reduced, the wound base was ruddy, and the wound bed preparation was completed. Conclusion: The application of moist healing theory in nursing care of breast cancer wound is obvious.","PeriodicalId":73634,"journal":{"name":"Journal of cancer science and clinical therapeutics","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69348166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Balachandran, Jennet Williams, David C. Bell, Anna Brown, P. Hurhangee, R. Ramakrishnan, S. Cleator, R. Coombes, O. Hatcher, F. Rehman, J. Stebbing, L. Kenny
{"title":"Impact of COVID-19 on Breast Cancer Treatment: A Tertiary Referral Centre Experience","authors":"K. Balachandran, Jennet Williams, David C. Bell, Anna Brown, P. Hurhangee, R. Ramakrishnan, S. Cleator, R. Coombes, O. Hatcher, F. Rehman, J. Stebbing, L. Kenny","doi":"10.26502/jcsct.5079125","DOIUrl":"https://doi.org/10.26502/jcsct.5079125","url":null,"abstract":"Background: The effect of the COVID-19 on breast cancer treatment is unknown. The pandemic’s impact on treatment delivery was assessed in patients undergoing chemotherapy treatment at a major London oncology centre. Methods: Treatment and medical records for all patients attending the chemotherapy unit and on outpatient treatment for breast cancer over an 8 week period (during first lockdown; 23rd March-17th May 2020) were compared to a similar time period in 2019. Results: Breast cancer diagnosis referrals fell by 38% mainly due to screening services halting which had a knock-on effect on patient numbers starting their first treatment (reduced by 34%). Neoadjuvant, adjuvant, and palliative patients were all affected, mostly at the start of lockdown. On-site chemotherapy and supportive treatments fell by 39% compared to 2019, mainly due to fewer number of bone-modifying agents. Towards the end of 8 week period, treatment numbers had nearly returned to normal. The system adapted by modifying treatment regimens, using telemedicine, increased use of supportive medications and less frequent blood tests. Conclusion: COVID-19’s global impact has significantly reduced breast cancer treatments given during the first lockdown. Whilst recovery is now evident, cancer services, patients, and clinical cancer research must be prioritised in future waves.","PeriodicalId":73634,"journal":{"name":"Journal of cancer science and clinical therapeutics","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69367565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. van Heerden, N. Moes, Katleen Balliauw, Elien Romaen, J. Verlooy, M. van den Akker, K. Norga
{"title":"The Management of Delayed Onset Cramps Related to Irinotecan during Oncological Treatment","authors":"J. van Heerden, N. Moes, Katleen Balliauw, Elien Romaen, J. Verlooy, M. van den Akker, K. Norga","doi":"10.26502/jcsct.5079130","DOIUrl":"https://doi.org/10.26502/jcsct.5079130","url":null,"abstract":"Background: Irinotecan-induced gastro-intestinal side effects are well described in the literature. The pathophysiology and treatment of diarrhea, especially acute onset, is the most understood. Yet delayed onset cramps and management have not been sufficiently documented. J Cancer Sci Clin Ther 2021; 5 (4): 448-458 DOI: 10.26502/jcsct.5079130 Journal of Cancer Science and Clinical Therapeutics 449 Materials: A case report of a nine-year-old girl diagnosed with rhabdomyosarcoma who was treated with irinotecan in the relapse setting, is presented. A limited literature review was done based on the challenges experienced during the management of a patient with delayed onset irinotecaninduced cramps. The pathophysiology of delayed onset irinotecan induced cramps is based on cholinergic, inflammatory and enzymatic factors as well as neural damage. Treatment was based on the etiology described in the literature with a positive result. Conclusion: Delayed onset irinotecan related cramps are part of a multifactorial etiology that should be approached systematically, especially when first line treatment does not yield an adequate response.","PeriodicalId":73634,"journal":{"name":"Journal of cancer science and clinical therapeutics","volume":"89 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69348061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hessa A Alsanad, Lama A Alrasheed, Reem R Alkharji, Nur Khadijah Mohd Zin, Abdulrahman A Alzahrani, Alaa T Alshareeda
{"title":"The Impact of Mastectomy on Self-Concept and Social Life: Decisional Conflicts for Breast Reconstruction","authors":"Hessa A Alsanad, Lama A Alrasheed, Reem R Alkharji, Nur Khadijah Mohd Zin, Abdulrahman A Alzahrani, Alaa T Alshareeda","doi":"10.26502/jcsct.5079133","DOIUrl":"https://doi.org/10.26502/jcsct.5079133","url":null,"abstract":"Background: Having a mastectomy affects a woman psychosocially, especially to adapt to the changes of her body. It is important to understand women's motivation for breast reconstruction surgery (BRS) to reconcile themselves J Cancer Sci Clin Ther 2021; 5 (4): 496-511 DOI: 10.26502/jcsct.5079133 Journal of Cancer Science and Clinical Therapeutics 497 with their own beliefs and desires. This study explored the factors that affect women's decision to have BRS after the mastectomy, the level of awareness of the available BRS options and their suggestions to improve the acceptance of BRS. Materials and methods: A questionnaire was distributed to patients diagnosed with BC in Saudi Arabia. Results: A total of 352 women were recruited for this cross-sectional study. Age and high educational attainment were significantly associated with a positive decision for BRS. Physical appearance and self-confidence were essential factors in the decision-making for BRS. The main barriers were the surgical risks and strong religious beliefs. Interestingly, both breasts removed affect women’s social life positively compared to those who had one breast removed. The majority (70%) of the sample did not know of the educational campaigns held by the Ministry of Health. The main suggestion to increase interest in BRS is the presence of clinicians throughout the treatment journey. Conclusion: Women diagnosed with BC should be involved in a personalized care plan, especially the group at a higher risk of developing negative body image feelings associated with a mastectomy.","PeriodicalId":73634,"journal":{"name":"Journal of cancer science and clinical therapeutics","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69348104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aferdita Stroka Koka, Laver Stroka, B. Çela, Ronny Khadra, A. Guy, F. Hyseni, J. Musa
{"title":"Alternative Treatment of NMSC Recurrent with NILS","authors":"Aferdita Stroka Koka, Laver Stroka, B. Çela, Ronny Khadra, A. Guy, F. Hyseni, J. Musa","doi":"10.26502/jcsct.5079126","DOIUrl":"https://doi.org/10.26502/jcsct.5079126","url":null,"abstract":"Throughout 2018 in the \"STROKA\" clinic in Tirana, are presented for alternative treatment 28 patients with recurrent non melanoma skin cancer (NMSC) after standard treatment with surgery, radiotherapy or together for one or more lesions. All patients are diagnosed with Basal Cell Carcinoma and Squamous Cell Carcinoma, and are treated with NILS which contains extracts of some Albanian plants such as Allium sativum, Juglans regia and Laurus nobilis. According to a certain methodology, the treatment of patients lasts from one to three months until the complete destruction of the tumor and the regeneration of the area below and around it. From the first session, the measure of the tumor was reduce and all the surface that has absorbed the Nils, was turn in a cruste. The crustes falls one after another until the tumor mass has end and the sound layer was reached. At this point, we stoped the sessions of treatment, because the process of regeneration starts. NILS solution is J Cancer Sci Clin Ther 2021; 5 (3): 405-413 DOI: 10.26502/jcsct.5079126 Journal of Cancer Science and Clinical Therapeutics 406 applied topically and the number of sessions varied from 314 in our 28 patients. After complete recovery, all are advised for periodic check-ups after 1, 2, 3, 6, 12, 18, 24, 30 and 36 months, without limiting them further.","PeriodicalId":73634,"journal":{"name":"Journal of cancer science and clinical therapeutics","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69367588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Aspects on the International Commission on Non-Ionizing Radiation Protection (ICNIRP) 2020 Guidelines on Radiofrequency Radiation","authors":"L. Hardell, Mona Nilsson, T. Koppel, M. Carlberg","doi":"10.26502/JCSCT.5079117","DOIUrl":"https://doi.org/10.26502/JCSCT.5079117","url":null,"abstract":"The International Commission on Non-Ionizing Radiation Protection (ICNIRP) published 2020 updated guidelines on radiofrequency (RF) radiation in the frequency range 100 kHz to 300 GHz. Harmful effects on human health and the environment at levels below the guidelines are downplayed although evidence is steadily increasing. Only thermal (heating) effects are acknowledged and therefore form the basis for the guidelines. Despite the increasing scientific evidence of non-thermal effects, the new ICNIRP guidelines are not lower compared with the previous levels. Expert groups from the WHO, the EU Commission and Sweden are to a large extent made up of members from ICNIRP, with no representative from the many scientists who are critical of the ICNIRP standpoint.","PeriodicalId":73634,"journal":{"name":"Journal of cancer science and clinical therapeutics","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69367986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H.S. Han, T. -, Jyh‐cherng Yu, M. Golshan, Huan-Ming Hsu, C. Chu, Z. Hong, C. Fu, Y. Chou, M. Dai, G. Liao
{"title":"Survival Benefits Associated with Surgery in Patients with Metastatic Breast Cancer by Breast Cancer Subtype","authors":"H.S. Han, T. -, Jyh‐cherng Yu, M. Golshan, Huan-Ming Hsu, C. Chu, Z. Hong, C. Fu, Y. Chou, M. Dai, G. Liao","doi":"10.26502/jcsct.5079127","DOIUrl":"https://doi.org/10.26502/jcsct.5079127","url":null,"abstract":"Background: Two randomized trials have examined the role of local therapy on survival in the stage IV setting of breast cancer, largely suggesting no benefit. However, the effect of surgery for stage IV disease amongst various breast cancer subtypes is not well characterized. In this study, we aimed to evaluate the survival benefit of surgery in patients with stage IV breast cancer based on molecular subtype. J Cancer Sci Clin Ther 2021; 5 (3): 414-425 DOI: 10.26502/jcsct.5079127 Journal of Cancer Science and Clinical Therapeutics 415 Methods: Using an institutional database, we extracted 255 women with a clinicopathologic confirmed diagnosis of stage IV breast cancer who were treated between January 2006 and October 2016. We collected patient data including age, clinical T stage, clinical N stage, histological grade, estrogen receptor, progesterone receptor, human epidermal growth factor receptor 2, and the use of radiotherapy, chemotherapy, targeted therapy and/or endocrine therapy. Correlates of overall survival (OS) and breast cancer-specific survival (BCSS) in the surgical and non-surgical groups were identified on multivariate analysis. Results: The median overall survival in the surgical group and the non-surgical group was 30.3 months and 20.7 months, respectively. There were significant differences between the two groups according to subtype in the distribution of OS and BCSS (P <0.001). On multivariate analysis for the OS and BCSS, using non-surgical group as a reference, there were significant improvement for the luminal B subtype (P=0.010). Conclusion: This study suggest that surgery of the primary breast tumor may have a positive impact on OS and BCSS in patients with stage IV breast cancer, especially in the luminal B subtype.","PeriodicalId":73634,"journal":{"name":"Journal of cancer science and clinical therapeutics","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69348050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Analytical Anisotropic Algorithm Calculation in Total Body Irradiation: A Comparison with Monte Carlo Calculation and Dosimetry","authors":"Saikkonen A, Ojala J, Keyrilainen J","doi":"10.26502/jcsct.5079136","DOIUrl":"https://doi.org/10.26502/jcsct.5079136","url":null,"abstract":"Purpose: This study aimed to investigate the feasibility and accuracy of an analytical anisotropic algorithm calculation of the Varian Eclipse treatment planning system in the TBI treatment planning at an extended source-to-surface distance of 400 cm. Materials and Methods: The TBI treatment was planned with the Varian Eclipse TPS using the AAA for the dose calculation. Monte Carlo calculations were performed using the EGSnrc code package. Percentage depth dose curves, central axis dose profiles and absolute doses of the 6 MV photon beams from the Varian TrueBeam linear accelerator were measured at an extended SSD of 400 cm in water, solid water and anthropomorphic phantoms. Results: Calculated and measured PDD curves were in good agreement at the depths of 30.0 cm or less. Calculated J Cancer Sci Clin Ther 2021; 5 (4): 532-547 DOI: 10.26502/jcsct.5079136 Journal of Cancer Science and Clinical Therapeutics 533 and measured central axis dose profiles were clinically acceptable, observing the largest uncertainties close the field edges. Absolute dose measurements in water phantoms showed that the MC and AAA calculations overestimated doses by up to 2.2 % and 1.8 %, respectively. In the anthropomorphic phantom, the difference between measured and calculated mean doses in the whole body volume was 1.0 % and 6.2 % for MC and AAA, respectively. In the AAA calculation, the largest observed difference was 8.3 % in the head. Conclusions: The Eclipse’s AAA calculation can be safely used for the TBI treatment planning at the extended SSD of 400 cm. However, in order to achieve a higher level of accuracy in the TBI planning, one must carefully validate the TPS at extended SSDs.","PeriodicalId":73634,"journal":{"name":"Journal of cancer science and clinical therapeutics","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69348163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Igbokwe Mc, Badmus Ta, Salako Aa, Obiajunwa Ei, O. O., Igbokwe Ca, D. ra
{"title":"Profile of Tissue Selenium Concentration In A Cohort Of Nigerian Men With Prostate Cancer","authors":"Igbokwe Mc, Badmus Ta, Salako Aa, Obiajunwa Ei, O. O., Igbokwe Ca, D. ra","doi":"10.26502/jcsct.5079140","DOIUrl":"https://doi.org/10.26502/jcsct.5079140","url":null,"abstract":"","PeriodicalId":73634,"journal":{"name":"Journal of cancer science and clinical therapeutics","volume":"59 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69348208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}