Journal of Anesthesia, Analgesia and Critical Care (Online)最新文献

筛选
英文 中文
One-year outcome and quality of life of patients with subarachnoid hemorrhage admitted to intensive care unit: a single-center retrospective pilot study. 重症监护室蛛网膜下腔出血患者的一年预后和生活质量:一项单中心回顾性试点研究。
Journal of Anesthesia, Analgesia and Critical Care (Online) Pub Date : 2025-01-03 DOI: 10.1186/s44158-024-00223-w
Carlo Bergamini, Etrusca Brogi, Sara Salvigni, Michele Romoli, Giovanni Bini, Alessandra Venditto, Elvis Lafe, Marcello D'Andrea, Luigino Tosatto, Maria Ruggiero, Vanni Agnoletti, Emanuele Russo
{"title":"One-year outcome and quality of life of patients with subarachnoid hemorrhage admitted to intensive care unit: a single-center retrospective pilot study.","authors":"Carlo Bergamini, Etrusca Brogi, Sara Salvigni, Michele Romoli, Giovanni Bini, Alessandra Venditto, Elvis Lafe, Marcello D'Andrea, Luigino Tosatto, Maria Ruggiero, Vanni Agnoletti, Emanuele Russo","doi":"10.1186/s44158-024-00223-w","DOIUrl":"10.1186/s44158-024-00223-w","url":null,"abstract":"<p><p>Patients admitted to intensive care unit (ICU) after non-traumatic subarachnoid hemorrhage (SAH) represent a group with distinctive characteristics and few data are available on long-term outcome in this population. We conducted a single-center retrospective study in an Italian intensive care unit. All patients with non-traumatic SAH (ICD-9-CM Diagnosis Code 430) admitted to ICU were included. Disability and quality of life were evaluated via telephone interview after 12-15 months after initial bleeding using GOSE and EuroQoL, respectively. Baseline and clinical course characteristics were analyzed to evaluate relation with poor outcome defined as GOSE ≤ 3. Final population consisted of 38 patients. Twenty-four patients (63.2%) had favorable outcome (GOSE ≥ 4). Among 29 patients (76.3%) who survived at 1 year, median EQ-5D Index was 0.743 (IQR 0.287), while median EQ-VAS was 74.79 (IQR 18.5). Median EQ-5D Index and median EQ-VAS were higher among patients with favorable outcome (EQ-5D Index p = 0.037, EQ-VAS p = 0.003). Among baseline characteristics, only HH scale showed a significant relation with disability at one year (p = 0.033). Between complications occurred during ICU-stay only early HICP was related with unfavorable outcome (p = 0.028). Higher HH scale and early HICP were related with unfavorable outcome. Among patients with unfavorable outcome, quality of life has a broad range of variability, and this result should be taken into account when reporting patient-centered outcomes.</p>","PeriodicalId":73597,"journal":{"name":"Journal of Anesthesia, Analgesia and Critical Care (Online)","volume":"5 1","pages":"2"},"PeriodicalIF":0.0,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11697876/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142928828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ciltius, Altius, Fortius! Our Olympic games: simulation training for potential casualties massive influx during Paris 2024! 西提乌斯,阿尔提乌斯,福提乌斯!我们的奥运会:潜在伤亡的模拟训练巴黎2024年期间大量涌入!
Journal of Anesthesia, Analgesia and Critical Care (Online) Pub Date : 2025-01-03 DOI: 10.1186/s44158-024-00220-z
Myriam Lamamri, Raphaëlle David, Emmanuel Weiss, Mathilde Holleville
{"title":"Ciltius, Altius, Fortius! Our Olympic games: simulation training for potential casualties massive influx during Paris 2024!","authors":"Myriam Lamamri, Raphaëlle David, Emmanuel Weiss, Mathilde Holleville","doi":"10.1186/s44158-024-00220-z","DOIUrl":"10.1186/s44158-024-00220-z","url":null,"abstract":"","PeriodicalId":73597,"journal":{"name":"Journal of Anesthesia, Analgesia and Critical Care (Online)","volume":"5 1","pages":"1"},"PeriodicalIF":0.0,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11697904/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142928806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analgosedation in patients with acute respiratory failure on noninvasive ventilation: is it truly safe? 无创通气急性呼吸衰竭患者的镇痛镇静:真的安全吗?
Journal of Anesthesia, Analgesia and Critical Care (Online) Pub Date : 2024-12-21 DOI: 10.1186/s44158-024-00221-y
Manuel Alberto Guerrero-Gutiérrez, Rafael Alfonso Reyes-Monge, Ignacio Rodríguez-Guevara, Diego Escarramán-Martínez, Orlando Rubén Pérez-Nieto
{"title":"Analgosedation in patients with acute respiratory failure on noninvasive ventilation: is it truly safe?","authors":"Manuel Alberto Guerrero-Gutiérrez, Rafael Alfonso Reyes-Monge, Ignacio Rodríguez-Guevara, Diego Escarramán-Martínez, Orlando Rubén Pérez-Nieto","doi":"10.1186/s44158-024-00221-y","DOIUrl":"10.1186/s44158-024-00221-y","url":null,"abstract":"","PeriodicalId":73597,"journal":{"name":"Journal of Anesthesia, Analgesia and Critical Care (Online)","volume":"4 1","pages":"84"},"PeriodicalIF":0.0,"publicationDate":"2024-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11663306/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142873602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intraoperative extracorporeal support for lung transplant: a systematic review and network meta-analysis. 肺移植术中体外支持:系统回顾和网络荟萃分析。
Journal of Anesthesia, Analgesia and Critical Care (Online) Pub Date : 2024-12-18 DOI: 10.1186/s44158-024-00214-x
Tommaso Pettenuzzo, Honoria Ocagli, Nicolò Sella, Alessandro De Cassai, Francesco Zarantonello, Sabrina Congedi, Maria Vittoria Chiaruttini, Elisa Pistollato, Marco Nardelli, Martina Biscaro, Mara Bassi, Giordana Coniglio, Eleonora Faccioli, Federico Rea, Dario Gregori, Paolo Navalesi, Annalisa Boscolo
{"title":"Intraoperative extracorporeal support for lung transplant: a systematic review and network meta-analysis.","authors":"Tommaso Pettenuzzo, Honoria Ocagli, Nicolò Sella, Alessandro De Cassai, Francesco Zarantonello, Sabrina Congedi, Maria Vittoria Chiaruttini, Elisa Pistollato, Marco Nardelli, Martina Biscaro, Mara Bassi, Giordana Coniglio, Eleonora Faccioli, Federico Rea, Dario Gregori, Paolo Navalesi, Annalisa Boscolo","doi":"10.1186/s44158-024-00214-x","DOIUrl":"10.1186/s44158-024-00214-x","url":null,"abstract":"<p><strong>Background: </strong>In the last decades, veno-arterial extracorporeal membrane oxygenation (V-A ECMO) has been gaining in popularity for intraoperative support during lung transplant (LT), being advocated for routinely use also in uncomplicated cases. Compared to off-pump strategy and, secondarily, to traditional cardiopulmonary bypass (CPB), V-A ECMO seems to offer a better hemodynamic stability and oxygenation, while data regarding blood product transfusions, postoperative recovery, and mortality remain unclear. This systematic review and network meta-analysis aims to evaluate the comparative efficacy and safety of V-A ECMO and CPB as compared to OffPump strategy during LT.</p><p><strong>Methods: </strong>A comprehensive literature search was conducted across multiple databases (PubMed Embase, Cochrane, Scopus) and was updated in February 2024. A Bayesian network meta-analysis (NMA), with a fixed-effect approach, was performed to compare outcomes, such as intraoperative needing of blood products, invasive mechanical ventilation (IMV) duration, intensive care unit (ICU) length of stay (LOS), surgical duration, needing of postoperative ECMO, and mortality, across different supports (i.e., intraoperative V-A (default (d) or rescue (r)) ECMO, CPB, or OffPump).</p><p><strong>Findings: </strong>Twenty-seven observational studies (6113 patients) were included. As compared to OffPump surgery, V-A ECMOd, V-A ECMOr, and CPB recorded a higher consumption of all blood products, longer IMV durations, prolonged ICU LOS, surgical duration, and higher mortalities. Comparing different extracorporeal supports, V-A ECMOd and, secondarily, V-A ECMOr overperformed CPB in nearly all above mentioned outcomes, except for RBC transfusions. The lowest rate of postoperative ECMO was recorded after OffPump surgery, while no differences were found comparing different extracorporeal supports. Finally, older age, male gender, and body mass index ≥ 25 kg/m<sup>2</sup> negatively impacted on RBC transfusions, ICU LOS, surgical duration, need of postoperative ECMO, and mortality, regardless of the intraoperative extracorporeal support investigated.</p><p><strong>Interpretation: </strong>This comparative network meta-analysis highlights that OffPump overperformed ECMO and CPB in all outcomes of interest, while, comparing different extracorporeal supports, V-A ECMOd and, secondarily, V-A ECMOr overperformed CPB in nearly all above mentioned outcomes, except for RBC transfusions. Older age, male gender, and higher BMI negatively affect several outcomes across different intraoperative strategies, regardless of the intraoperative extracorporeal support investigated. Future prospective studies are necessary to optimize and standardize the intraoperative management of LT.</p>","PeriodicalId":73597,"journal":{"name":"Journal of Anesthesia, Analgesia and Critical Care (Online)","volume":"4 1","pages":"81"},"PeriodicalIF":0.0,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11658095/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142856940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Amitriptyline-perphenazine therapy for persistent idiopathic facial pain: translational perspectives from a retrospective study. 阿米替林-奋那嗪治疗持续性特发性面部疼痛:一项回顾性研究的翻译观点。
Journal of Anesthesia, Analgesia and Critical Care (Online) Pub Date : 2024-12-18 DOI: 10.1186/s44158-024-00217-8
Maurizio Marchesini, Giulia Topi, Cesare Bonezzi, Laura Demartini
{"title":"Amitriptyline-perphenazine therapy for persistent idiopathic facial pain: translational perspectives from a retrospective study.","authors":"Maurizio Marchesini, Giulia Topi, Cesare Bonezzi, Laura Demartini","doi":"10.1186/s44158-024-00217-8","DOIUrl":"10.1186/s44158-024-00217-8","url":null,"abstract":"<p><strong>Background: </strong>Persistent idiopathic facial pain (PIFP) can be challenging, both in its diagnosis, which appears to be purely exclusionary, and in its treatment, which currently lacks a gold standard. Amitriptyline is considered a first-line therapy, although not always effective. Recent insights into the role of dopamine in facial pain suggest that a novel therapeutic approach could target the dopamine system.</p><p><strong>Methods: </strong>This study aimed to retrospectively evaluate the efficacy of treatment with amitriptyline-perphenazine association in patients with severe PIFP. Thirty-one patients were given a regimen dose of amitriptyline-perphenazine at dosages ranging between 10/2 and 20/4 mg and were then retrospectively analyzed. We evaluated the following outcomes, referred to the last week prior to follow-up visits: NRS score for pain intensity (minimum, maximum, and average), the number of attacks, and SF-36 questionnaire for quality of life. Comparisons were made between pre- and post-treatment.</p><p><strong>Results: </strong>Thirty-one patients over 35 were screened. At baseline, average NRS was 5 ± 0.93 (CI 95%: 4.6-5.3), and the median number of breakthrough episodes over last week was 5 ± 1.57 (CI 95%: 4-6) with a maximum NRS = 9 ± 0.89 (CI 95%: 8-9). After treatment, average NRS was 4.1 ± 0.93 (CI 95%: 3.8-4.5; p < 0.001), maximum NRS was 6.1 ± 1.60 (CI 95%: 5.5-6.6), and the median number of attacks was 4 ± 0.99 (IC 95%: 3-4) (p < 0.001). Regarding SF-36 questionnaire, the most improved parameters were quality of life related to pain (25.89 ± 12.48 vs 31.19 ± 13.44; p < 0.001) and physical function (69.56 ± 17.84 vs 84.17 ± 20.99; p < 0.001).</p><p><strong>Conclusion: </strong>Despite limitations, the pain scores, the frequency of the attacks, and quality of life were found to be significantly improved after treatment. Although results are not broad based given the small sample size, the combination of amitriptyline and perphenazine may be an effective and well-tolerated treatment in patients with PIFP. It is abundantly clear that dopaminergic pathways play a key role in pain modulation, yet the underlying mechanisms have not been fully understood, requiring further investigation.</p>","PeriodicalId":73597,"journal":{"name":"Journal of Anesthesia, Analgesia and Critical Care (Online)","volume":"4 1","pages":"83"},"PeriodicalIF":0.0,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11656548/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142856916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analgesic efficacy and safety of erector spinae plane block versus serratus anterior plane block in breast surgery-a meta-analysis and systematic review of randomized controlled trials. 竖脊肌平面阻滞与前锯肌平面阻滞在乳房手术中的镇痛疗效和安全性——随机对照试验的荟萃分析和系统评价。
Journal of Anesthesia, Analgesia and Critical Care (Online) Pub Date : 2024-12-18 DOI: 10.1186/s44158-024-00218-7
Samiullah Shaikh, Umm E Salma Shabbar Banatwala, Paranshi Desai, Muhammad Arham Khan, Rimsha Bint-E-Hina, Sidra Samad, Muhammad Hamza Sikandari, Ali Nawaz, Rana Ijaz, Shayan Asmat, Abeer Fatima, Harim Mirza, Noor Mahal Azam, Qurat Ul Ain Muhammad, Satesh Kumar, Mahima Khatri
{"title":"Analgesic efficacy and safety of erector spinae plane block versus serratus anterior plane block in breast surgery-a meta-analysis and systematic review of randomized controlled trials.","authors":"Samiullah Shaikh, Umm E Salma Shabbar Banatwala, Paranshi Desai, Muhammad Arham Khan, Rimsha Bint-E-Hina, Sidra Samad, Muhammad Hamza Sikandari, Ali Nawaz, Rana Ijaz, Shayan Asmat, Abeer Fatima, Harim Mirza, Noor Mahal Azam, Qurat Ul Ain Muhammad, Satesh Kumar, Mahima Khatri","doi":"10.1186/s44158-024-00218-7","DOIUrl":"10.1186/s44158-024-00218-7","url":null,"abstract":"<p><strong>Background: </strong>Mastectomy and breast-conserving surgery are key interventions for breast cancer, a leading cause of cancer-related mortality in women. Many undergoing breast surgery experience postoperative pain compromising their functionality and quality of life. While multiple pain management strategies are available, evidence comparing the erector spinae (ESPB) and serratus anterior plane blocks (SAPB) for improving post-surgical pain management in breast cancer surgery patients is limited. Therefore, we investigated the efficacy and safety of these two regional anesthesia techniques.</p><p><strong>Methods: </strong>After PROSPERO registration, we systematically searched PubMed, Google Scholar, and Cochrane Library until May 2024. Risk ratios (RR) were calculated for dichotomous outcomes and standard mean differences (SMD) or mean differences (MD) were computed for continuous data. RevMan Review Manager 5.4.1 was used for the data analysis and generation of forest plots as well as funnel plots. The Cochrane Risk of Bias tool 2.0 (18) and Grades of Recommendation, Assessment, Development, and Evaluation (GRADE) guidelines were used to appraise and evaluate the evidence (19).</p><p><strong>Results: </strong>A total of 9 randomized control trials enrolling 550 patients were included. Static pain scores at 0, 6, 8, 12, and 24 h after surgery, dynamic pain scores computed at 0, 8, 12, and 24 h after surgery and area under the curve (AUC) static pain score at all time points between 0 and 24 h (SMD (HKSJ 95% CI) - 0.27 [- 0.99, 0.45]) did not significantly vary with either plane block. Postoperative morphine consumption in the first 24 h and the number of patients requesting analgesia were significantly greater in those receiving SAPB [MD: - 1.41 (95% C.I. - 2.70, - 0.13), p = 0.03] and [RR: 1.28 (95% C.I. 1.00, 1.63), p = 0.05], respectively. The time to first postoperative analgesic use was significantly greater among those administered ESPB [MD: 1.55 h, (95% C.I. 1.02, 2.09), p < 0.01]. Patient satisfaction scores and the incidence of nausea and vomiting were similar across both groups.</p><p><strong>Conclusions: </strong>While pain scores with either block are comparable, ESPB reduces postoperative morphine consumption and may be the favorable option in breast cancer patients undergoing surgery.</p>","PeriodicalId":73597,"journal":{"name":"Journal of Anesthesia, Analgesia and Critical Care (Online)","volume":"4 1","pages":"82"},"PeriodicalIF":0.0,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11657579/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142856921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Deep sedation in lateral position for preterm infants during cerebral magnetic resonance imaging: a pilot study. 脑磁共振成像期间早产儿侧位深度镇静:一项试点研究。
Journal of Anesthesia, Analgesia and Critical Care (Online) Pub Date : 2024-12-18 DOI: 10.1186/s44158-024-00216-9
Fabio Sbaraglia, Simona Gaudino, Eloisa Tiberi, Federica Maiellare, Giorgia Spinazzola, Rossella Garra, Filomena Della Sala, Daniela Maria Micci, Rosellina Russo, Francesca Riitano, Giuseppe Ferrara, Giovanni Vento, Marco Rossi
{"title":"Deep sedation in lateral position for preterm infants during cerebral magnetic resonance imaging: a pilot study.","authors":"Fabio Sbaraglia, Simona Gaudino, Eloisa Tiberi, Federica Maiellare, Giorgia Spinazzola, Rossella Garra, Filomena Della Sala, Daniela Maria Micci, Rosellina Russo, Francesca Riitano, Giuseppe Ferrara, Giovanni Vento, Marco Rossi","doi":"10.1186/s44158-024-00216-9","DOIUrl":"10.1186/s44158-024-00216-9","url":null,"abstract":"<p><strong>Introduction: </strong>Respiratory adverse events are common during the sedation of preterm babies, often needing active airway support. During magnetic resonance imaging, this occurrence could extend the acquisition time, with a negative impact on the thermic and metabolic homeostasis. The aim of the study is to verify if lying in a lateral position instead of supine could improve the safe quality of sedation, without worsening the quality of imaging.</p><p><strong>Methods: </strong>This study was performed as a single-center, prospective study at a university-affiliated tertiary care center. A consultant provided deep sedation with sevoflurane 3-4% delivered by an external mask, in the lateral decubitus position. All patients were evaluated for the incidence of apnea and desaturation, quality of imaging obtained, the timing of imaging acquisition, and thermic and metabolic homeostasis.</p><p><strong>Results: </strong>We enrolled 23 consecutive preterm babies born < 37 weeks gestational age, candidates for sedation for elective brain magnetic resonance imaging. All patients completed the radiological procedure in 30 min (SD ± 6.39 min) without complications requiring exam interruption. Only one patient (4%) experienced a transient desaturation, while 2 neonates (9%) showed apnea lasting > 20 s. On average, there was a 1 °C decrease in body temperature and full enteral feeding was resumed within 1.5 h. Neuroradiologists rated the quality of the images obtained as high.</p><p><strong>Conclusions: </strong>Lateral lying seems to be a viable option for sedated preterm babies during magnetic resonance imaging with a low risk of intervention for apnea and a reduced impact on thermic and metabolic homeostasis. Quality of imaging would be preserved maintaining correct scheduling of standard care.</p><p><strong>Trial registration: </strong>The study was registered at www.</p><p><strong>Clinicaltrials: </strong>gov before enrollment (NCT05776238 on December, 21th 2023).</p>","PeriodicalId":73597,"journal":{"name":"Journal of Anesthesia, Analgesia and Critical Care (Online)","volume":"4 1","pages":"80"},"PeriodicalIF":0.0,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11654365/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142856939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Navigating the integration of large language models in healthcare: challenges, opportunities, and implications under the EU AI Act. 在医疗保健中导航大型语言模型的集成:欧盟人工智能法案下的挑战、机遇和影响。
Journal of Anesthesia, Analgesia and Critical Care (Online) Pub Date : 2024-12-02 DOI: 10.1186/s44158-024-00215-w
Elena Bignami, Michele Russo, Roberto Lanza, Valentina Bellini
{"title":"Navigating the integration of large language models in healthcare: challenges, opportunities, and implications under the EU AI Act.","authors":"Elena Bignami, Michele Russo, Roberto Lanza, Valentina Bellini","doi":"10.1186/s44158-024-00215-w","DOIUrl":"10.1186/s44158-024-00215-w","url":null,"abstract":"","PeriodicalId":73597,"journal":{"name":"Journal of Anesthesia, Analgesia and Critical Care (Online)","volume":"4 1","pages":"79"},"PeriodicalIF":0.0,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11613792/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142774835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Severe bronchiolitis before and after the COVID-19 pandemic: a retrospective database analysis by the Italian Network of PICU study group (TIPNet). COVID-19 大流行前后的严重支气管炎:意大利 PICU 研究小组网络 (TIPNet) 的回顾性数据库分析。
Journal of Anesthesia, Analgesia and Critical Care (Online) Pub Date : 2024-11-26 DOI: 10.1186/s44158-024-00210-1
Francesca Izzo, Rosanna I Comoretto, Angela Amigoni, Marco Daverio, Elena Zoia, Veronica Diotto, Francesco Sacco, Claudio Nettuno, Anna Tessari, Enzo Picconi, Maria Cristina Mondardini, Gaia Milvia Bregant, Andrea Wolfler, Dario Gregori, Anna Camporesi
{"title":"Severe bronchiolitis before and after the COVID-19 pandemic: a retrospective database analysis by the Italian Network of PICU study group (TIPNet).","authors":"Francesca Izzo, Rosanna I Comoretto, Angela Amigoni, Marco Daverio, Elena Zoia, Veronica Diotto, Francesco Sacco, Claudio Nettuno, Anna Tessari, Enzo Picconi, Maria Cristina Mondardini, Gaia Milvia Bregant, Andrea Wolfler, Dario Gregori, Anna Camporesi","doi":"10.1186/s44158-024-00210-1","DOIUrl":"10.1186/s44158-024-00210-1","url":null,"abstract":"<p><strong>Background: </strong>The first post-COVID-19 pandemic year demonstrated an unusual bronchiolitis epidemic in both hemispheres and has been attributed to the removal of barriers implemented during SARS-CoV-2 infection. Several countries reported an increase in respiratory syncytial virus (RSV) bronchiolitis, with more hospitalizations and a greater need for respiratory support. We aimed to evaluate the consequences of the COVID-19 pandemic on the epidemiology and management of severe bronchiolitis in pediatric intensive care units (PICUs) in Italy.</p><p><strong>Methods: </strong>Multicenter, retrospective, cohort database analysis. All children younger than 24 months admitted to 7 PICUs from October 2017 to April 2023 diagnosed with bronchiolitis were included. We compared patients from pre-COVID and post-COVID eras, excluding patients from the 2020-2021 season due to low numbers. Logistic regression models were used to assess the impact of the pre-/post-COVID period on the need for invasive ventilation.</p><p><strong>Results: </strong>Seven hundred fifteen patients were admitted to PICU during the study period, 451 patients pre-COVID and 251 patients post-COVID. Patients in the post-COVID group were older, had more comorbidities, and had higher Pediatric Index of Mortality scores at admission but the need for respiratory support was not significantly different. There was high variability in bronchiolitis management across centers. Presenting pre-COVID was protective against the risk of mechanical ventilation, adjusted for age and disease severity at admission (OR 0.38, 95% CI 0.16-0.89), while RSV infection increased the risk of intubation (OR 2.49, 95% CI 1.1-5.63).</p><p><strong>Conclusions: </strong>PICUs have faced an unexpected peak of significantly more severe cases of bronchiolitis after the COVID-19 pandemic, which did not require increased respiratory support.</p>","PeriodicalId":73597,"journal":{"name":"Journal of Anesthesia, Analgesia and Critical Care (Online)","volume":"4 1","pages":"78"},"PeriodicalIF":0.0,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11600936/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142735199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Understanding neuropathic pain: the role of neurophysiological tests in unveiling underlying mechanisms. 了解神经性疼痛:神经生理学测试在揭示潜在机制中的作用。
Journal of Anesthesia, Analgesia and Critical Care (Online) Pub Date : 2024-11-18 DOI: 10.1186/s44158-024-00212-z
Caterina Maria Leone, Andrea Truini
{"title":"Understanding neuropathic pain: the role of neurophysiological tests in unveiling underlying mechanisms.","authors":"Caterina Maria Leone, Andrea Truini","doi":"10.1186/s44158-024-00212-z","DOIUrl":"10.1186/s44158-024-00212-z","url":null,"abstract":"<p><p>Neuropathic pain, arising from lesions of the somatosensory nervous system, presents with diverse symptoms including ongoing pain, paroxysmal pain, and provoked pain, usually accompanied by sensory deficits. Understanding the pathophysiological mechanisms behind these symptoms is crucial for targeted treatment strategies. Neurophysiological techniques such as nerve conduction studies, reflexes, and evoked potentials help elucidate these mechanisms by assessing large myelinated non-nociceptive fibres and small nociceptive fibres. This argumentative review highlights the importance of tailored neurophysiological assessments for improving our understanding of the pathophysiological mechanisms behind neuropathic pain symptoms.</p>","PeriodicalId":73597,"journal":{"name":"Journal of Anesthesia, Analgesia and Critical Care (Online)","volume":"4 1","pages":"77"},"PeriodicalIF":0.0,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11575013/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142669861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信