Journal of advanced periodontology & implant dentistry最新文献_第2页

Histologic evidence of the effect of fibroblast growth factor 2 on periodontal regeneration: A scoping review of animal studies. 成纤维细胞生长因子2对牙周再生影响的组织学证据：动物研究的范围综述。

Journal of advanced periodontology & implant dentistry Pub Date : 2025-02-12 eCollection Date: 2025-06-01 DOI: 10.34172/japid.2025.3487

Fazele Atarbashi-Moghadam, Saede Atarbashi-Moghadam, Termeh Sarrafan Sadeghi, Niloofar Taghipour, Ali Azadi

{"title":"Histologic evidence of the effect of fibroblast growth factor 2 on periodontal regeneration: A scoping review of animal studies.","authors":"Fazele Atarbashi-Moghadam, Saede Atarbashi-Moghadam, Termeh Sarrafan Sadeghi, Niloofar Taghipour, Ali Azadi","doi":"10.34172/japid.2025.3487","DOIUrl":"10.34172/japid.2025.3487","url":null,"abstract":"Background: Fibroblast growth factor 2 (FGF2) is a signaling molecule used successfully in periodontal regeneration. This review aims to evaluate histologic evidence of the effect of FGF2 on the regeneration of periodontal ligament (PDL), cementum, and alveolar bone in animal studies.Methods: A scoping review of the animal models was conducted to assess the histologic evidence of the effect of FGF2 on periodontal regeneration. The search was performed for English articles published until January 1, 2025. Any histologic findings regarding PDL, cementum, or bone regeneration and other outcomes such as epithelial down-growth, ankylosis, neovascularization, root resorption, and any clinical observation through histologic or radiographic analysis were considered as desired outcomes.Results: The MEDLINE and Scopus databases were searched, and 516 records were identified. After the screening, 22 articles met the inclusion criteria and were included in the study. The primary outcomes measured were any histologic findings regarding the regeneration of PDL, cementum, and alveolar bone. The included studies investigated the effect of FGF2 on the various periodontal defects, including 1-, 2-, and 3-wall vertical defects, circumferential defects, furcation involvement, and recession-type defects. In all types of defects, PDL, cementum, and alveolar bone formation were enhanced in most groups containing FGF2 compared to groups without FGF2. Most studies mentioned better radiographic results regarding bone formation or bone fill.Conclusion: FGF2 can promote regeneration in all parts of periodontal tissue in surgically created periodontal defects in animal models, including cementum, PDL, and alveolar bone.","PeriodicalId":73584,"journal":{"name":"Journal of advanced periodontology & implant dentistry","volume":"17 2","pages":"90-102"},"PeriodicalIF":0.0,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12261071/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144651348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Salivary alkaline phosphatase levels and alveolar bone crest changes in immediate vs. delayed implant placement. 唾液碱性磷酸酶水平和牙槽骨嵴的变化在立即与延迟种植体放置。

Journal of advanced periodontology & implant dentistry Pub Date : 2025-02-12 eCollection Date: 2025-03-01 DOI: 10.34172/japid.2025.006

Bahareh Hekmat, Masoumeh Amani, Farhad Aghmasheh, Zahra Mohammad Hasani

{"title":"Salivary alkaline phosphatase levels and alveolar bone crest changes in immediate vs. delayed implant placement.","authors":"Bahareh Hekmat, Masoumeh Amani, Farhad Aghmasheh, Zahra Mohammad Hasani","doi":"10.34172/japid.2025.006","DOIUrl":"https://doi.org/10.34172/japid.2025.006","url":null,"abstract":"Background: Dental implant therapy is a top option for replacing lost or unsalvageable teeth. The most common placement protocols are immediate and delayed. A key factor for successful treatment is the stability of the marginal bone, which can be evaluated through radiography and salivary biomarkers. This study evaluated the relationship between salivary alkaline phosphatase levels and the alveolar crest bone height in immediate and delayed implants.Methods: This study involved 62 patients: 31 for immediate and 31 for delayed implant placement in posterior jaw regions. Unstimulated saliva (5 mL) was collected from all the patients before surgery and at 14- and 4-month postoperative intervals to assess salivary alkaline phosphatase activity using spectrophotometry. Intraoral periapical digital radiographs were taken immediately after surgery and 2 and 4 months postoperatively to evaluate alveolar crest bone height. Measurements at the mesial and distal implant sites were analyzed using Scanora software.Results: No significant differences were found in salivary alkaline phosphatase activity or alveolar crest bone resorption based on gender, implant timing, or jaw region (P>0.05). However, patient age significantly correlated with alkaline phosphatase activity and bone resorption (P<0.05). There was no correlation between alkaline phosphatase levels and alveolar crest bone height.Conclusion: Salivary alkaline phosphatase cannot be considered a reliable diagnostic biomarker for evaluating the condition of the alveolar crest bone around dental implants.","PeriodicalId":73584,"journal":{"name":"Journal of advanced periodontology & implant dentistry","volume":"17 1","pages":"40-45"},"PeriodicalIF":0.0,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12010478/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144058790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical effectiveness of aloe vera gel as an adjunct to mechanical debridement in patients with periodontitis: A systematic review and meta-analysis. 芦荟凝胶作为牙周炎患者机械清创辅助治疗的临床效果：一项系统综述和荟萃分析。

Journal of advanced periodontology & implant dentistry Pub Date : 2025-01-20 eCollection Date: 2025-03-01 DOI: 10.34172/japid.2025.002

Nisha Ashifa, Krishnan Viswanathan, Sivapragasam Srinivasan, Varsha K Pavithran, Shiva Shankar, Rajasekar Sundaram, Senthil Kumar, Divvi Anusha

{"title":"Clinical effectiveness of aloe vera gel as an adjunct to mechanical debridement in patients with periodontitis: A systematic review and meta-analysis.","authors":"Nisha Ashifa, Krishnan Viswanathan, Sivapragasam Srinivasan, Varsha K Pavithran, Shiva Shankar, Rajasekar Sundaram, Senthil Kumar, Divvi Anusha","doi":"10.34172/japid.2025.002","DOIUrl":"https://doi.org/10.34172/japid.2025.002","url":null,"abstract":"Background: This study aimed to evaluate the clinical effect of aloe vera gel as an adjunct to scaling and root planing (SRP) on plaque index (PI), gingival index (GI), and probing pocket depth (PPD) in periodontitis treatment.Methods: Randomized controlled trials (RCTs) were included, focusing on aloe vera gel as an adjunct to SRP in periodontitis patients. An extensive literature search was conducted across PubMed, PubMed Central, Scopus, OVID, Google Scholar, and Cochrane Library databases up to October 2024. The risk of bias was assessed using the Revised Cochrane Risk of Bias tool (ROB 2.0), and statistical analysis was performed using Review Manager 5.4.1.Results: Fifteen RCTs were included in this systematic review, and separate meta-analyses were conducted for each outcome. For PI, the random effects model showed a mean difference (MD) of -0.23 (95% CI: -0.69, 0.23), favoring the experimental group (P=0.33). The fixed effects model for PI favored the control group (MD=0.12; P=0.20). For GI, the random effects model favored the experimental group (MD=-0.28, P=0.01), while the fixed effects model favored the control group (MD=0.17; P<0.001). For PPD, the random effects model favored the experimental group (MD=-0.45, P=0.009).Conclusion: As an adjunct to SRP, aloe vera gel significantly improved PI, GI, and PPD in periodontitis patients.Trial registration: PROSPERO ID: CRD42020201315.","PeriodicalId":73584,"journal":{"name":"Journal of advanced periodontology & implant dentistry","volume":"17 1","pages":"15-25"},"PeriodicalIF":0.0,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12010479/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144022522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Expression of Lamin A gene in periodontitis: A cross-sectional study. Lamin A基因在牙周炎中的表达：一项横断面研究。

Journal of advanced periodontology & implant dentistry Pub Date : 2025-01-20 eCollection Date: 2025-03-01 DOI: 10.34172/japid.2025.003

Naser Sargolzaie, Jalil Tavakkol-Afshari, Raziyeh Mohebati, Faeze Basiri, Arsalan Shahri, Mahdiye Fasihi Ramandi

{"title":"Expression of Lamin A gene in periodontitis: A cross-sectional study.","authors":"Naser Sargolzaie, Jalil Tavakkol-Afshari, Raziyeh Mohebati, Faeze Basiri, Arsalan Shahri, Mahdiye Fasihi Ramandi","doi":"10.34172/japid.2025.003","DOIUrl":"https://doi.org/10.34172/japid.2025.003","url":null,"abstract":"Background: The host defense process against invading bacteria leads to the destruction of the periodontium. Lamin A is an important protein for protecting DNA and preventing premature cell aging. This study investigated the expression of the Lamin A gene in periodontitis patients.Methods: Using an analytical cross-sectional design, Lamin A gene expression was evaluated in 23 periodontitis patients and 24 healthy individuals referred to the Periodontology Department of Mashhad Dental School and Hekmat Clinic, Mashhad, Iran. Gingival samples were collected, followed by RNA extraction, cDNA synthesis, and real-time PCR. Statistical analyses were conducted using SPSS.Results: While the age distribution did not show significant differences between the groups, gender distribution was statistically different. Therefore, the study focuses on comparing Lamin A gene expression levels between the patient and healthy groups, separated by gender. Considering the analysis of 47 gingival tissue samples, the Lamin A gene expression level was higher in healthy participants, with the difference being statistically significant only in female participants (198.45±54.00 in healthy females vs. 143.52±29.29 in periodontitis females).Conclusion: These findings suggest that the expression of the Lamin A gene was higher in healthy individuals than in periodontitis patients. More studies are needed to draw more accurate conclusions. If confirmed in larger studies, this protein group might serve as potential biomarkers, enhancing periodontitis assessment strategies.","PeriodicalId":73584,"journal":{"name":"Journal of advanced periodontology & implant dentistry","volume":"17 1","pages":"36-39"},"PeriodicalIF":0.0,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12010475/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144030401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Salivary carcinoembryonic antigen in desquamative gingivitis: A comparative study in oral lichenoid reactions before and after topical corticosteroid therapy. 唾液癌胚抗原在脱屑性牙龈炎中的作用：局部皮质类固醇治疗前后口腔类地衣反应的比较研究。

Journal of advanced periodontology & implant dentistry Pub Date : 2025-01-20 eCollection Date: 2025-03-01 DOI: 10.34172/japid.2025.004

Ayla Bahramian, Farzaneh Pakdel, Solmaz Pourzare Mehrbani, Ehsan Golchin, Ensiyeh Maljaei, Maryam Hosseinpour Sarmadi, Tara Deljavanghodrati, Katayoun Katebi

{"title":"Salivary carcinoembryonic antigen in desquamative gingivitis: A comparative study in oral lichenoid reactions before and after topical corticosteroid therapy.","authors":"Ayla Bahramian, Farzaneh Pakdel, Solmaz Pourzare Mehrbani, Ehsan Golchin, Ensiyeh Maljaei, Maryam Hosseinpour Sarmadi, Tara Deljavanghodrati, Katayoun Katebi","doi":"10.34172/japid.2025.004","DOIUrl":"https://doi.org/10.34172/japid.2025.004","url":null,"abstract":"Background: Desquamative gingivitis is an immunological chronic disease that is considered precancerous and has the potential to develop into squamous cell carcinoma. Carcinoembryonic antigen (CEA), a common tumor marker, increases in many cancers. The present study compared salivary CEA levels in desquamative gingivitis before and after topical corticosteroid therapy.Methods: This case‒control study was conducted in the Department of Oral and Maxillofacial Medicine, Tabriz Faculty of Dentistry. Twenty patients with desquamative gingivitis in oral lichen planus (OLP) background were selected as the case group, with 20 healthy individuals as the control group. Desquamative gingivitis lesions were confirmed with biopsies. Salivary samples were obtained from both groups. Second, salivary samples were collected from the case group after a course of topical corticosteroid therapy. Salivary CEA levels were measured by a monobind kit using the ELISA method. Independent and paired t-tests were used to analyze the data in SPSS 17. P<0.05 was considered statistically significant.Results: Before treatment, CEA levels were significantly higher in the case group (174.06±95.55) than in the control group (55.66±41.26 ng/mL) (P<0.001). Salivary CEA levels in the case group decreased significantly after the treatment (96.77±66.25 ng/mL) compared to before treatment (174.06±95.55 ng/mL) (P<0.001).Conclusion: This study demonstrated that CEA levels significantly decreased in patients with desquamative gingivitis associated with oral lichenoid reaction after receiving topical corticosteroid therapy.","PeriodicalId":73584,"journal":{"name":"Journal of advanced periodontology & implant dentistry","volume":"17 1","pages":"26-30"},"PeriodicalIF":0.0,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12010480/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144047771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The association of gene polymorphisms with peri-implant mucositis and peri-implantitis: A systematic review and meta-analysis. 基因多态性与种植体周围粘膜炎和种植体周围炎的关联：一项系统综述和荟萃分析。

Journal of advanced periodontology & implant dentistry Pub Date : 2025-01-06 eCollection Date: 2025-06-01 DOI: 10.34172/japid.2025.3432

Soheil Shahbazi, Saharnaz Esmaeili, Anahita Moscowchi, Reza Amid, Mahdi Kadkhodazadeh

{"title":"The association of gene polymorphisms with peri-implant mucositis and peri-implantitis: A systematic review and meta-analysis.","authors":"Soheil Shahbazi, Saharnaz Esmaeili, Anahita Moscowchi, Reza Amid, Mahdi Kadkhodazadeh","doi":"10.34172/japid.2025.3432","DOIUrl":"10.34172/japid.2025.3432","url":null,"abstract":"Background: The current study aimed to systematically review the existing evidence on potential links between gene polymorphisms and the occurrence of peri-implant mucositis (PIM) or peri-implantitis (PI).Methods: The electronic search was executed through six databases in November 2022: PubMed, Embase, Google Scholar, Scopus, Cochrane CENTRAL, and Web of Science. The search sought studies delving into the possible association of gene polymorphisms with PIM or PI. To showcase the effect size, odds ratios along with 95% confidence intervals were used. The meta-analysis was performed on polymorphisms/alleles reported in at least two studies.Results: The initial search yielded 2162 results, which were reduced to 1327 following deduplication. After evaluating titles, abstracts, and full texts, 30 studies were deemed suitable for inclusion. Forty-nine gene polymorphisms were examined among 50 PIM patients, 1603 PI patients, and 2407 healthy controls spanning seven ethnicities. The meta-analysis showed that IL-1α -889 (95% CI: 1.070‒2.850, OR=1.746, P=0.026), IL-1β+3954 (95% CI: 1.265‒2.851, OR=1.899, P=0.002), and OPG -3618 (95% CI: 1.158‒2.983, OR=1.859, P=0.010) gene polymorphisms significantly differed between healthy controls and PI patients. However, IL-1β -511, IL-6 -174, OPG -3617, and TNF-α -308 gene polymorphisms did not significantly alter PI risk. Due to insufficient data, performing a meta-analysis on PIM was not feasible.Conclusion: The findings suggest that IL-1α -889, IL-1β+3954, and OPG -3618 gene polymorphisms are associated with the predisposition to PI. However, further research among diverse populations is warranted to draw more definitive conclusions.","PeriodicalId":73584,"journal":{"name":"Journal of advanced periodontology & implant dentistry","volume":"17 2","pages":"77-89"},"PeriodicalIF":0.0,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12261067/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144651351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Deep margin elevation; Indications and periodontal considerations. 深边缘抬升；适应症和牙周注意事项。

Journal of advanced periodontology & implant dentistry Pub Date : 2024-11-06 eCollection Date: 2024-01-01 DOI: 10.34172/japid.2024.024

Parnian Alizadeh Oskoee, Sana Dibazar

引用次数: 0

Effect of orthodontic forced eruption for implant site development in the maxillary esthetic zone: A systematic review of clinical data. 正畸强制出牙对上颌美观区种植体发育的影响：临床资料的系统回顾。

Journal of advanced periodontology & implant dentistry Pub Date : 2024-10-07 eCollection Date: 2024-01-01 DOI: 10.34172/japid.2024.022

Mohammadreza Talebi Ardakani, Aida Kheiri, Majid Torabzadeh, Amirhosein Mahmoudian, Mohammad Hossien Talebi, Amir Talebi

{"title":"Effect of orthodontic forced eruption for implant site development in the maxillary esthetic zone: A systematic review of clinical data.","authors":"Mohammadreza Talebi Ardakani, Aida Kheiri, Majid Torabzadeh, Amirhosein Mahmoudian, Mohammad Hossien Talebi, Amir Talebi","doi":"10.34172/japid.2024.022","DOIUrl":"https://doi.org/10.34172/japid.2024.022","url":null,"abstract":"Dental implant placement in the esthetic zone is associated with challenges for clinicians. The best esthetic outcome of this procedure can be obtained through precise management of hard and soft tissue. Orthodontic forced eruption (OFE) has presented an alternative approach to augment hard and soft tissues, which can be applied rapidly or slowly. OFE of hopeless teeth with its periodontal attachment results in a favorable implant preparation site. Therefore, the present systematic review evaluated the effect of implant site preparation using OFE in hopeless teeth. A complete electronic search was performed in PubMed/MEDLINE, Scopus, and Google Scholar from June 2020 to November 2023. The search was limited to clinical English language studies. Studies were excluded if OFE was performed without implant placement. Finally, 15 studies with a total of 21 teeth, all located in the maxillary anterior region, were included in this study. In eight studies, bone grafting procedures were performed before implant placement. Using OFE could rapidly prepare the implant site by enhancing hard and soft tissues. However, additional interventions like guided bone regeneration should be considered case-dependent.","PeriodicalId":73584,"journal":{"name":"Journal of advanced periodontology & implant dentistry","volume":"16 2","pages":"173-178"},"PeriodicalIF":0.0,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11699265/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142933891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relationship of hemoglobin levels and distribution and severity of gingival melanin pigmentation: An exploratory cross-sectional study. 血红蛋白水平与牙龈黑色素沉着分布及严重程度的关系：一项探索性横断面研究。

Journal of advanced periodontology & implant dentistry Pub Date : 2024-09-11 eCollection Date: 2024-01-01 DOI: 10.34172/japid.2024.020

Riya Achamma Daniel, Veena Hr, Suman Basavaraju

{"title":"Relationship of hemoglobin levels and distribution and severity of gingival melanin pigmentation: An exploratory cross-sectional study.","authors":"Riya Achamma Daniel, Veena Hr, Suman Basavaraju","doi":"10.34172/japid.2024.020","DOIUrl":"https://doi.org/10.34172/japid.2024.020","url":null,"abstract":"Background: Recurrence of gingival pigmentation following depigmentation procedures is common, raising the question of the influence of an underlying cause, if any. Melanin, a non-hemoglobin-derived brown pigment, is the most common endogenous pigment contributing to gingival pigmentation. Hemoglobin derivatives are among the other prime pigments that contribute to gingival color. This exploratory cross-sectional study evaluated the influence of hemoglobin levels on the distribution and severity of gingival melanin pigmentation in periodontitis, gingivitis, and healthy periodontium.Methods: Twenty subjects with periodontitis (group 1), gingivitis (group 2), and healthy periodontium (group 3) were recruited in this observational study, totaling 60 subjects. The hemoglobin levels in g/dL and Hedin Melanin Index (HMI-1977) scores were recorded for all subjects, and relevant statistical tests were applied (P<0.05).Results: A negative correlation was observed between the hemoglobin levels and the HMI scores for the whole sample and each group. This correlation was statistically significant for the whole sample and for the gingivitis group in which the correlation was moderate.Conclusion: The inverse and significant relation between the hemoglobin levels and distribution and severity of melanin pigmentation observed for the whole sample and the gingivitis group requires further research and validation to identify and manage the confounding factors in the treatment of gingival pigmentation.","PeriodicalId":73584,"journal":{"name":"Journal of advanced periodontology & implant dentistry","volume":"16 2","pages":"103-108"},"PeriodicalIF":0.0,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11699264/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142934000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of the effect of albumin with platelet-rich fibrin (Alb-PRF) gel and hyaluronic acid gel injection on interdental papilla reconstruction: A randomized clinical trial. 白蛋白与富血小板纤维蛋白（Alb-PRF）凝胶和透明质酸凝胶注射液在牙间乳头重建中的作用比较：一项随机临床试验。

Journal of advanced periodontology & implant dentistry Pub Date : 2024-09-11 eCollection Date: 2024-01-01 DOI: 10.34172/japid.2024.018

Bardia Vadiati Saberi, Ali Khalighi Sigaroudi, Mobina Kamani, Elahe Rafiei

{"title":"Comparison of the effect of albumin with platelet-rich fibrin (Alb-PRF) gel and hyaluronic acid gel injection on interdental papilla reconstruction: A randomized clinical trial.","authors":"Bardia Vadiati Saberi, Ali Khalighi Sigaroudi, Mobina Kamani, Elahe Rafiei","doi":"10.34172/japid.2024.018","DOIUrl":"https://doi.org/10.34172/japid.2024.018","url":null,"abstract":"Background: The interdental papilla plays a crucial role in the esthetic of the smile. Papilla reconstruction surgery is one of the most unpredictable periodontal procedures. This study compared the effect of the non-surgical application of a commercial hyaluronic acid (HA) gel with an autogenous gel named \"albumin with platelet-rich fibrin\" (Alb-PRF) on interdental papilla reconstruction.Methods: This trial was conducted on 46 incomplete interdental papillae with class I or II defects. The papillae were randomly divided into two experimental groups, and commercial HA or Alb-PRF (prepared from the patient's peripheral blood) was injected into the papillae twice at a 21-day interval. Three and six months after the intervention, photographs were taken from the black triangles and the black surfaces compared to each other. Patient satisfaction and dental plaque index were also evaluated at the end of the study.Results: The black triangles' surfaces significantly decreased over time in both experimental groups (P<0.001). However, there were no significant differences between the two groups (P=0.994). The intervention resulted in the patients' relative satisfaction with the treatment results in both groups. However, the difference between the two groups was not statistically significant (P=0.965). In addition, no statistically significant differences were observed in plaque index between the two groups (P=0.566).Conclusion: HA or Alb-PRF injection into the incomplete interdental papilla may restore the soft tissue to a great extent and lead to patient satisfaction by reducing the area of black triangles that threaten esthetics; however, more studies are needed.","PeriodicalId":73584,"journal":{"name":"Journal of advanced periodontology & implant dentistry","volume":"16 2","pages":"109-115"},"PeriodicalIF":0.0,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11699259/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142933872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0