Journal of advanced periodontology & implant dentistry最新文献

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Evaluation of gingival biotype and bone thickness in maxillary implant patients: A clinical study based on cone-beam computed tomography. 基于锥束ct的上颌种植患者牙龈生物型和骨厚度评价的临床研究。
Journal of advanced periodontology & implant dentistry Pub Date : 2026-03-16 eCollection Date: 2026-04-01 DOI: 10.34172/japid.026.3716
Motahare Damavandi, Razieh Azizian, Narges Shojaei
{"title":"Evaluation of gingival biotype and bone thickness in maxillary implant patients: A clinical study based on cone-beam computed tomography.","authors":"Motahare Damavandi, Razieh Azizian, Narges Shojaei","doi":"10.34172/japid.026.3716","DOIUrl":"10.34172/japid.026.3716","url":null,"abstract":"<p><strong>Background: </strong>The relationship between gingival biotype (GB) and bone thickness is paramount for optimal maxillary implant outcomes. This study aimed to determine the correlation between GB and buccal bone thickness (BBT) and buccal bone height (BBH) in candidates for immediate maxillary implant placement using cone-beam computed tomography (CBCT).</p><p><strong>Methods: </strong>This cross-sectional study assessed 54 patients from the Periodontology Department at Ilam University of Medical Sciences Dental School. Gingival thickness (GT), buccal bone measurements (BBT and BBH), and clinical parameters, including keratinized gingival width (KGW) and papillary height (PH), were recorded using Michigan probes and CBCT scans. Statistical analyses (Mann-Whitney and Kruskal-Wallis tests) were conducted to evaluate associations between variables, with <i>P</i><0.05 considered significant.</p><p><strong>Results: </strong>Of the participants, 62.96% had a thick GB and 37.04% had a thin GB. Thin biotypes were significantly more prevalent among females (<i>P</i><0.05). The thick GB group exhibited significantly greater KGW and overall mean BBT compared to the thin GB group (<i>P</i><0.05). Conversely, no statistically significant differences were observed between thick and thin biotypes regarding overall mean BBH or PH (<i>P</i>>0.05).</p><p><strong>Conclusion: </strong>A thick gingival biotype is anatomically associated with greater buccal bone thickness and keratinized gingival width. However, there were no statistically significant differences in buccal or papillary bone height between the different gingival biotypes. Thin gingival biotypes are more prevalent among females.</p>","PeriodicalId":73584,"journal":{"name":"Journal of advanced periodontology & implant dentistry","volume":"18 2","pages":"90-97"},"PeriodicalIF":0.0,"publicationDate":"2026-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13241591/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148201133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tooth-derived graft for preservation and reconstruction of orofacial bones: A comprehensive review. 牙源性移植物用于保存和重建口面骨:一个全面的综述。
Journal of advanced periodontology & implant dentistry Pub Date : 2026-03-16 eCollection Date: 2026-07-01 DOI: 10.34172/japid.026.3834
Mina Shekarian, Pardis Amani Beni, Ghazal Hassanzadehganroudsari, Abbasali Khademi
{"title":"Tooth-derived graft for preservation and reconstruction of orofacial bones: A comprehensive review.","authors":"Mina Shekarian, Pardis Amani Beni, Ghazal Hassanzadehganroudsari, Abbasali Khademi","doi":"10.34172/japid.026.3834","DOIUrl":"10.34172/japid.026.3834","url":null,"abstract":"<p><p>Bone loss in the craniofacial region can result from various causes, requiring grafting for restoration. Each type of bone graft has advantages and disadvantages. In recent years, an increasing number of clinical research has used extracted teeth as graft biomaterials. This study aimed to outline the use of teeth as bone graft material, describe a general protocol for producing tooth graft material, compare various manufacturing methods, and assess tooth-derived grafts relative to other bone graft materials. The review was based on electronic database searches in Scopus, PubMed, Cochrane, Web of Science, and Google Scholar, using various combinations of keywords such as \"autogenous graft,\" \"autologous graft,\" \"human dentin,\" \"dentin matrix,\" \"tooth graft,\" \"demineralized dentin matrix,\" and related terms applied to titles, abstracts, and keywords. Tooth-derived grafts demonstrate promising outcomes comparable to conventional bone graft materials. However, further research is necessary to standardize protocols and validate clinical applications.</p>","PeriodicalId":73584,"journal":{"name":"Journal of advanced periodontology & implant dentistry","volume":"18 3","pages":"163-173"},"PeriodicalIF":0.0,"publicationDate":"2026-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13437216/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148681294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Successful dental implant rehabilitation in a posterior mandibular site affected by florid cemento-osseous dysplasia: A case report. 成功种植牙康复在下颌后部位的影响丰富的骨质发育不良:一个病例报告。
Journal of advanced periodontology & implant dentistry Pub Date : 2026-02-22 eCollection Date: 2026-07-01 DOI: 10.34172/japid.026.4070
Nima Naddafpour, Hassan Semyari, Hadise Semyari, Rozhan Khaledtaj, Hossein Semyari
{"title":"Successful dental implant rehabilitation in a posterior mandibular site affected by florid cemento-osseous dysplasia: A case report.","authors":"Nima Naddafpour, Hassan Semyari, Hadise Semyari, Rozhan Khaledtaj, Hossein Semyari","doi":"10.34172/japid.026.4070","DOIUrl":"10.34172/japid.026.4070","url":null,"abstract":"<p><p>Florid cemento-osseous dysplasia (FCOD) is a benign fibro-osseous disorder characterized by altered and poorly vascularized bone, which complicates implant placement by increasing the risk of infection and impaired healing. This case report documents the successful placement and one-year follow-up of two dental implants in the posterior mandible of a 45-year-old female patient with FCOD. Radiographic and clinical evaluations confirmed stable osseointegration and successful functional restoration, with no complications or changes in lesion size during follow-up. These findings suggest that, with careful patient selection, the use of atraumatic surgical techniques, meticulous infection control, appropriate postoperative oral care, and consistent follow-up, dental implant therapy can be successfully performed in selected cases of FCOD. However, due to the limited reported cases, extensive longitudinal studies are required to guide implant therapy in patients with FCOD.</p>","PeriodicalId":73584,"journal":{"name":"Journal of advanced periodontology & implant dentistry","volume":"18 3","pages":"183-1878"},"PeriodicalIF":0.0,"publicationDate":"2026-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13437517/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148681253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Socket preservation with and without lovastatin in combination with synthetic bone graft substitute: A double-blind clinical trial. 洛伐他汀联合或不联合人工骨替代物保存窝:一项双盲临床试验。
Journal of advanced periodontology & implant dentistry Pub Date : 2026-02-02 eCollection Date: 2026-04-01 DOI: 10.34172/japid.026.3919
Amirhossein Farahmand, Behzad Houshmand, Amir Reza Shirazi, Yassin Attar Zadeh, Soheil Taghavi Namin, Maryam Zohary, Mohammad Reza Sadeghi
{"title":"Socket preservation with and without lovastatin in combination with synthetic bone graft substitute: A double-blind clinical trial.","authors":"Amirhossein Farahmand, Behzad Houshmand, Amir Reza Shirazi, Yassin Attar Zadeh, Soheil Taghavi Namin, Maryam Zohary, Mohammad Reza Sadeghi","doi":"10.34172/japid.026.3919","DOIUrl":"10.34172/japid.026.3919","url":null,"abstract":"<p><strong>Background: </strong>The present study examined how bone improvement techniques, particularly the use of lovastatin with ridge preservation strategies, affect bone maintenance after tooth extraction. The goal of these strategies is to potentially decrease bone resorption and enhance the quality of alveolar bone, while also taking into account the associated risks of using high doses of statins.</p><p><strong>Methods: </strong>Twenty healthy patients undergoing bone grafting after tooth extraction in the anterior region of the maxilla were randomly divided into groups A and B. After non-invasive extraction, group A received a synthetic bone graft substitute combined with 10 mg of lovastatin, while group B received a synthetic bone graft alone. The graft was placed in the tooth socket and covered with a collagen cone for support. After nine months, a histomorphometric analysis assessed horizontal changes, using a clipper in the area compared to pre-treatment clinical measurements (<i>P</i>≤0.05).</p><p><strong>Results: </strong>The study examined 40 areas and found that the bone formation rate was 51.69% for those receiving only a synthetic bone graft substitute. When combined with 10 mg of lovastatin, the bone formation rate increased to 60.79%, indicating a significant improvement. The group receiving only the synthetic graft had an average of 1.70 mm leftover particles, while the lovastatin group had only 0.4844 mm particles, suggesting that lovastatin reduced residual material. Additionally, the lovastatin group exhibited a smaller ridge width and no signs of inflammation or foreign body reaction. In contrast, the group receiving only Nanobone showed inflammatory responses, primarily from mononuclear cells.</p><p><strong>Conclusion: </strong>According to the results, lovastatin shows promise in enhancing osteogenesis, narrowing the ridge, and decreasing residual connective tissue, while avoiding inflammation and foreign body reactions.The study was registered on clinicaltrials.gov under the ID NCT03981601.</p>","PeriodicalId":73584,"journal":{"name":"Journal of advanced periodontology & implant dentistry","volume":"18 2","pages":"80-89"},"PeriodicalIF":0.0,"publicationDate":"2026-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13241593/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148201120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Remote anchorage implants as an emerging treatment modality for the severely atrophic maxilla. 远端支抗种植体作为一种治疗上颌骨严重萎缩的新方法。
Journal of advanced periodontology & implant dentistry Pub Date : 2026-01-05 eCollection Date: 2026-01-01 DOI: 10.34172/japid.026.4247
Mohammadreza Talebi Ardakani, Aida Kheiri
{"title":"Remote anchorage implants as an emerging treatment modality for the severely atrophic maxilla.","authors":"Mohammadreza Talebi Ardakani, Aida Kheiri","doi":"10.34172/japid.026.4247","DOIUrl":"10.34172/japid.026.4247","url":null,"abstract":"","PeriodicalId":73584,"journal":{"name":"Journal of advanced periodontology & implant dentistry","volume":"18 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2026-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12935377/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147313277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development and evaluation of a PLGA/TiO2 nanocomposite for periodontal applications: Synthesis, characterization, and cytocompatibility with human gingival fibroblasts-An in vitro study. 牙周应用的PLGA/TiO2纳米复合材料的开发和评价:合成、表征和与人牙龈成纤维细胞的细胞相容性-一项体外研究
Journal of advanced periodontology & implant dentistry Pub Date : 2025-12-22 eCollection Date: 2026-04-01 DOI: 10.34172/japid.026.3939
Atabak Kashefimehr, Samira Mohammad Mirzapour, Motahare Sharifyrad, Samira Beiraghisalek
{"title":"Development and evaluation of a PLGA/TiO<sub>2</sub> nanocomposite for periodontal applications: Synthesis, characterization, and cytocompatibility with human gingival fibroblasts-An in vitro study.","authors":"Atabak Kashefimehr, Samira Mohammad Mirzapour, Motahare Sharifyrad, Samira Beiraghisalek","doi":"10.34172/japid.026.3939","DOIUrl":"10.34172/japid.026.3939","url":null,"abstract":"<p><strong>Background: </strong>Titanium dioxide (TiO<sub>2</sub>) nanoparticles exhibit promising antibacterial and structural properties but raise concerns of cytotoxicity in oral soft tissues. Incorporating TiO<sub>2</sub> into biocompatible polymers such as poly(lactic-co-glycolic acid) (PLGA) may reduce these adverse effects and improve clinical applicability in periodontal therapy.</p><p><strong>Methods: </strong>TiO<sub>2</sub> nanoparticles were synthesized via a modified sol-gel method and incorporated into PLGA matrices with and without polyvinylpyrrolidone (PVP) as a stabilizer. The formulations were characterized using Fourier-transform infrared (FTIR) spectroscopy, field emission scanning electron microscopy (FESEM), thermogravimetric analysis (TGA), dynamic light scattering (DLS), and x-ray diffraction (XRD). Cytocompatibility was evaluated using the MTT assay on HGF cells across concentrations of 1-100 μg/mL after 24 and 48 h.</p><p><strong>Results: </strong>TiO<sub>2</sub> nanoparticles alone induced significant, dose- and time-dependent cytotoxicity, reducing cell viability to ~45% at 100 μg/mL after 48 h (<i>P</i><0.01). Pure PLGA maintained>90% cell viability at all tested concentrations. The PLGA/TiO<sub>2</sub> nanocomposite showed markedly reduced cytotoxicity, maintaining>80% viability even at 100 μg/mL. Incorporation of PVP improved nanoparticle dispersion, as confirmed by FESEM and DLS, and enhanced the thermal stability of the composite.</p><p><strong>Conclusion: </strong>Encapsulation of TiO<sub>2</sub> within a PLGA matrix significantly mitigated cytotoxicity while preserving structural stability, with PVP further improving homogeneity and heat resistance. These findings highlight the potential of PLGA/TiO<sub>2</sub> nanocomposites as safe and effective candidates for periodontal wound dressings, implant coatings, or regenerative scaffolds.</p>","PeriodicalId":73584,"journal":{"name":"Journal of advanced periodontology & implant dentistry","volume":"18 2","pages":"103-113"},"PeriodicalIF":0.0,"publicationDate":"2025-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13241592/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148200953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigation of attachment and proliferation of MG-63 osteoblast-like cells to titanium disks in the presence of iPRF (injectable platelet-rich fibrin) or CGF (Concentrated Growth Factor): A laboratory study. MG-63成骨细胞样细胞在iPRF(可注射富血小板纤维蛋白)或CGF(浓缩生长因子)存在下附着和增殖的研究:一项实验室研究。
Journal of advanced periodontology & implant dentistry Pub Date : 2025-12-13 eCollection Date: 2026-01-01 DOI: 10.34172/japid.026.3383
Maryam Torshabi, Zeinab Rezaei Esfahrood, Behzad Houshmand, Seyed Hosein Tabatabaee
{"title":"Investigation of attachment and proliferation of MG-63 osteoblast-like cells to titanium disks in the presence of iPRF (injectable platelet-rich fibrin) or CGF (Concentrated Growth Factor): A laboratory study.","authors":"Maryam Torshabi, Zeinab Rezaei Esfahrood, Behzad Houshmand, Seyed Hosein Tabatabaee","doi":"10.34172/japid.026.3383","DOIUrl":"10.34172/japid.026.3383","url":null,"abstract":"<p><strong>Background: </strong>The attachment of the dental implant to the host bone (osteointegration) is considered a critical factor in the success of implant treatment. Osteoblasts are the primary cells in the osteointegration process. Today, compounds containing growth factors are used to shorten osteointegration time and increase the treatment success rate. This study evaluated the effects of iPRF (injectable platelet-rich fibrin) and CGF (concentrated growth factor) platelet extracts on the attachment and proliferation of MG-63 osteoblast-like cells over titanium disk surfaces.</p><p><strong>Methods: </strong>Titanium pieces with a length of 12.1 mm and a width of 3.8 mm were prepared. The MG-63 cell viability, attachment, and proliferation on titanium disks were evaluated in the presence of prepared extracts from iPRF and CGF using methyl thiazolyl tetrazolium (MTT) assay and scanning electron microscopy (SEM).</p><p><strong>Results: </strong>The results of the direct exposure of different concentrations of extracts on MG-63 cells cultured on the polystyrene surface of cell culture plates in the absence of fetal bovine serum (FBS) showed no significant difference between different concentrations of iPRF and CGF extracts in the first 24 hours after exposure (<i>P</i>>0.05). However, 48 hours after exposure, CGF extracts showed better effects (<i>P</i><0.05). In the first 24 hours, MG-63 cell attachment to the titanium disks was significantly higher after exposure to CGF compared to iPRF and the control group (<i>P</i><0.05). Nevertheless, 48 hours after culturing, no significant differences were observed in MG-63 survival, proliferation, and attachment between iPRF, CGF, and the control group (absence of iPRF and CGF) (<i>P</i>>0.05).</p><p><strong>Conclusion: </strong>The results showed a better short-term (first 24 hours after exposure) effect of CGF on primary cell survival, attachment, and proliferation compared to iPRF; however, this superiority disappeared over time.</p>","PeriodicalId":73584,"journal":{"name":"Journal of advanced periodontology & implant dentistry","volume":"18 1","pages":"3-10"},"PeriodicalIF":0.0,"publicationDate":"2025-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12913209/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146230101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk-based efficacy of systemic and local antibiotics in nonsurgical treatment of peri-implantitis: A systematic review and meta-analysis. 基于风险的全身和局部抗生素非手术治疗种植体周围炎的疗效:一项系统综述和荟萃分析。
Journal of advanced periodontology & implant dentistry Pub Date : 2025-12-09 eCollection Date: 2026-04-01 DOI: 10.34172/japid.026.3971
Masoumeh Faramarzi, Sajjad Pourkaveh, Adileh Shirmohammadi, Mehrnoosh Sadighi, Sevda Mashhadi Jolfaei, Elnaz Ziaeirad, Amir Zandesh
{"title":"Risk-based efficacy of systemic and local antibiotics in nonsurgical treatment of peri-implantitis: A systematic review and meta-analysis.","authors":"Masoumeh Faramarzi, Sajjad Pourkaveh, Adileh Shirmohammadi, Mehrnoosh Sadighi, Sevda Mashhadi Jolfaei, Elnaz Ziaeirad, Amir Zandesh","doi":"10.34172/japid.026.3971","DOIUrl":"10.34172/japid.026.3971","url":null,"abstract":"<p><strong>Background: </strong>Peri-implantitis is a prevalent inflammatory condition that compromises the long-term stability of dental implants. With its rising incidence, adjunctive therapies to nonsurgical mechanical debridement, particularly antibiotics, have gained attention. This systematic review evaluated the efficacy of systemic and local antibiotics as adjuncts to nonsurgical peri-implantitis treatment, focusing on probing depth (PD) reduction, bleeding on probing (BOP), and clinical attachment level (CAL).</p><p><strong>Methods: </strong>In accordance with the PRISMA 2020 guidelines, randomized controlled trials (RCTs) were screened. Data extraction and quality assessment were performed independently by two reviewers, and the quantitative synthesis was conducted using the CMA3 software.</p><p><strong>Results: </strong>Out of 93 screened records, six RCTs were included in this systematic review. Five studies investigated the effects of systemic treatment, and only one RCT reported the outcomes of topical antibiotic use. The quality of the studies was unclear in five studies and low in one study. Both systemic and local antibiotics demonstrated clinical benefits when combined with mechanical debridement. Reported adverse effects were generally mild. Overall, antibiotic therapy was associated with a greater decrease in PD (mean difference: -0.66, 95% confidence intervals: -1.014, -0.318, <i>P</i><0.001; I<sup>2</sup> : 76.97, <i>P</i> value for heterogeneity<0.01). In the subgroup analyses, systemic therapy was associated with better outcomes.</p><p><strong>Conclusion: </strong>Based on the limited available evidence, antibiotics may offer adjunctive benefits in the nonsurgical management of peri-implantitis. Protocol heterogeneity and limited long-term data highlight the need for standardized regimens, assessment of antimicrobial resistance, high-quality long-term RCTs, and cost-effective studies in this regard.</p>","PeriodicalId":73584,"journal":{"name":"Journal of advanced periodontology & implant dentistry","volume":"18 2","pages":"72-79"},"PeriodicalIF":0.0,"publicationDate":"2025-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13241590/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148201174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of periodontitis on micro and macro vascular complications of diabetes: A systematic review. 牙周炎对糖尿病微血管和大血管并发症的影响:一项系统综述。
Journal of advanced periodontology & implant dentistry Pub Date : 2025-12-04 eCollection Date: 2026-01-01 DOI: 10.34172/japid.026.3353
Farhan Musaie, Setareh Garousi, Mehregan Shahrokhi, Mahsa Babareshani, Danial Zamani, Zahra Ashrafi, Ala Shadbin, Ali Rezvanimehr, Zahra Sanei, Mehran Mottahedi, Nima Rahimipetrudi, Nozhan Azimi, Niloofar Deravi, Fatemeh Arabpour, Hamed Taheri
{"title":"Effects of periodontitis on micro and macro vascular complications of diabetes: A systematic review.","authors":"Farhan Musaie, Setareh Garousi, Mehregan Shahrokhi, Mahsa Babareshani, Danial Zamani, Zahra Ashrafi, Ala Shadbin, Ali Rezvanimehr, Zahra Sanei, Mehran Mottahedi, Nima Rahimipetrudi, Nozhan Azimi, Niloofar Deravi, Fatemeh Arabpour, Hamed Taheri","doi":"10.34172/japid.026.3353","DOIUrl":"10.34172/japid.026.3353","url":null,"abstract":"<p><strong>Background: </strong>Periodontitis (PD) is a chronic inflammatory disease of the oral cavity. PD can adversely affect glycemic control and cause macro- and micro-vascular diseases in diabetic patients. This article aims to systematically review the association between periodontitis and micro- and macro-vascular complications of diabetes.</p><p><strong>Methods: </strong>This review was conducted under the Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA). A thorough search of the Scopus and PubMed databases was performed up to 2022. English articles were included.</p><p><strong>Results: </strong>In this study, seven studies with 29,679 participants investigated the relationship between periodontitis and micro- and macro-vascular complications. There were two cohort studies, six cross-sectional studies, and one case‒control study. Follow-up durations ranged from 6 months to 11.64 years. The reports were published between 2002 and 2022. There was a relationship between periodontitis and the microvascular complications of diabetes in four studies. One study found no significant association between periodontitis and the microvascular complications of diabetes. The correlation between coronary heart disease (CHD) and periodontal disease was confirmed by one study. Furthermore, another study found that periodontitis increased the risk of cerebral and myocardial infarctions.</p><p><strong>Conclusion: </strong>The present study demonstrated that diabetes mellitus (DM) patients with periodontitis are at an increased risk of macro- and micro-vascular complications, particularly myocardial and cerebral infarctions.</p>","PeriodicalId":73584,"journal":{"name":"Journal of advanced periodontology & implant dentistry","volume":"18 1","pages":"48-54"},"PeriodicalIF":0.0,"publicationDate":"2025-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12913210/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146230029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of autogenous tooth vs. autogenous bone grafts on periodontal phenotype around immediate implants: A randomized clinical trial. 自体牙与自体骨移植物对牙周表型的影响:一项随机临床试验。
Journal of advanced periodontology & implant dentistry Pub Date : 2025-12-02 eCollection Date: 2026-01-01 DOI: 10.34172/japid.026.4099
Adileh Shirmohammadi, Elnaz Ziaei-Rad, Leila Roshangar, Samira Mohammad Mirzapour, Fatemeh Aghaziarati
{"title":"Effect of autogenous tooth vs. autogenous bone grafts on periodontal phenotype around immediate implants: A randomized clinical trial.","authors":"Adileh Shirmohammadi, Elnaz Ziaei-Rad, Leila Roshangar, Samira Mohammad Mirzapour, Fatemeh Aghaziarati","doi":"10.34172/japid.026.4099","DOIUrl":"10.34172/japid.026.4099","url":null,"abstract":"<p><strong>Background: </strong>Immediate implant placement can result in a horizontal defect between the implant and alveolar bone, potentially affecting osseointegration and esthetic outcomes. Grafting this space supports bone regeneration. This study compared the effectiveness of autogenous tooth-derived and autogenous bone grafts for horizontal gap augmentation in the maxillary anterior region.</p><p><strong>Methods: </strong>This parallel-arm randomized, single-masked clinical trial enrolled patients attending the Tabriz University of Medical Sciences School of Dentistry, who were candidates for immediate implant placement in the maxillary anterior region. After implant placement, the control sites (n=11) received autogenous bone grafts. In contrast, the intervention sites (n=11) received autogenous dentin grafts to fill the horizontal gap between the implant and the buccal wall (jumping gap). A connective tissue graft was subsequently placed in both groups to enhance buccal soft tissue. Buccal bone thickness (measured 2 mm and 5 mm below the marginal crest) and soft tissue thickness were measured at two points at the time of surgery and again six months postoperatively. Data were analyzed using paired t-tests to assess changes within each group and independent t-tests to compare differences between the two groups.</p><p><strong>Results: </strong>Both groups showed significant increases in buccal bone and soft tissue thickness compared with baseline. At 2 mm below the marginal crest, buccal bone thickness did not differ significantly between the two groups (<i>P</i>=0.401). At 5 mm below the marginal crest, the autogenous bone graft group showed significantly greater bone thickness (2.15±0.21 mm) than the dentin graft group (1.50±0.53 mm, <i>P</i>=0.001). There was no significant difference in buccal soft tissue thickness changes between the bone graft (1.15±0.18 mm) and dentin graft (1.1±0.17 mm) groups.</p><p><strong>Conclusion: </strong>Both autogenous dentin and bone grafts effectively enhanced buccal bone and soft tissue thickness around immediate implants. Autogenous bone grafts produced significantly greater increases in buccal bone at 5 mm below the marginal crest. <b>Trial Registration.</b> Iranian Registry of Clinical Trials (IRCT), IRCT20110726007128N11, Trial ID 86072.</p>","PeriodicalId":73584,"journal":{"name":"Journal of advanced periodontology & implant dentistry","volume":"18 1","pages":"32-40"},"PeriodicalIF":0.0,"publicationDate":"2025-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12913200/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146230020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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