Journal of 3D printing in medicine最新文献

{"title":"The use of in-house patient-specific 3D printed models in plastic-, orthopedic and neurosurgical planning: a preliminary report","authors":"R. Mehrzad, Erika Denour, Joseph W. Crozier, Albert S. Woo","doi":"10.2217/3dp-2023-0009","DOIUrl":"https://doi.org/10.2217/3dp-2023-0009","url":null,"abstract":"Aim: A limited number of studies have attempted to quantify the advantages of using in-house 3D printed models. We designed a pilot study to assess the value of in-house production of patient-specific 3D-printed models in pre-surgical planning. Methods: A 12-question survey was designed and sent to surgeons to assess any purported benefits of 3D-printed anatomic models. In-house 3D model printing was completed on a Stratasys J750 Polyjet printer. Each 3D printed model was delivered to the supervising surgeon days before the procedure for final validation. The 3D models were subsequently utilized in the operating room. Results: A total of 50 surveys were completed for a response rate of 100%. Approximately 94% of the participants strongly agreed that the 3D-printed model was a valuable clinical tool for pre-surgical planning. The majority of the respondents (78%) reported improved surgical efficiency. Conclusion: 3D models is a valuable tool for surgical planning.","PeriodicalId":73578,"journal":{"name":"Journal of 3D printing in medicine","volume":"123 30","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139616033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emerging frontiers in surgical training: progress in 3D printed gel models","authors":"Shijie Yu, Xiaodong Xu, Liang Ma, LiDong Cao, Jinlei Mao, Hao Chen, Jing Zhang, Zhifei Wang","doi":"10.2217/3dp-2023-0003","DOIUrl":"https://doi.org/10.2217/3dp-2023-0003","url":null,"abstract":"With the increasing complexity and difficulty of surgical procedures, there is an urgent need for empirical and high-fidelity surgical teaching tools. Whereas in the past, teaching tools included cadavers and animals, today, with the development of three-dimensional (3D) printing technology, the creation of patient-specific organ models is possible. This technology provides an effective solution for preoperative rehearsal, thus providing surgery residents with a more realistic simulation environment. This study aimed to provide an overview of the use of personalized 3D printing in various types of surgery through a scoping review, outline their bottlenecks, and provide an outlook. Significant advancements have been made in 3D-printed gel organ models for surgical applications. However, future advancements require interdisciplinary collaborations, medical–engineering integration and novel techniques. Addressing challenges in preservation, instrument response, ultrasound performance and mechanical properties is crucial. Enhancing these aspects will improve the capabilities of organ models, benefiting both medical practitioners and patients.","PeriodicalId":73578,"journal":{"name":"Journal of 3D printing in medicine","volume":"62 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139246131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advancing the field of 3D bioprinting: an interview with Ibrahim T Ozbolat","authors":"Ibrahim T Ozbolat","doi":"10.2217/3dp-2023-0010","DOIUrl":"https://doi.org/10.2217/3dp-2023-0010","url":null,"abstract":"Journal of 3D Printing in MedicineAhead of Print InterviewOpen AccessAdvancing the field of 3D bioprinting: an interview with Ibrahim T OzbolatIbrahim T OzbolatIbrahim T Ozbolat *Author for correspondence: E-mail Address: ito1@psu.eduhttps://orcid.org/0000-0001-8328-4528Department of Engineering Science & Mechanics, Biomedical Engineering, Materials Research Institute, The Huck Institutes of Life Sciences, Penn State University, University Park, PA 16802, USASearch for more papers by this authorPublished Online:12 Oct 2023https://doi.org/10.2217/3dp-2023-0010AboutSectionsPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareShare onFacebookTwitterLinkedInRedditEmail Keywords: 3D bioprinting3D modelsbiofabricationclinical translationimmunotherapyBiographyIbrahim T Ozbolat is a Professor of Engineering and Mechanics at The Pennsylvania State University. With significant contributions to the field of 3D bioprinting, Ibrahim's research focuses on the generation of 3D-printed tissues and organs and the development of 3D bioprinting processes and related technologies for a range of purposes including regenerative medicine, drug testing and understanding of diseases. He serves as the principal investigator of the Ozbolat lab, an interdisciplinary lab drawing on experts from various backgrounds including medicine, chemistry, biomedical engineering, industrial engineering and mechanical engineering. This collaborative approach fosters innovation and seeks to address complex challenges in 3D bioprinting.What inspired your interest in bioprinting?I hold dual Bachelor of Science degrees from the Middle East Technical University (Ankara, Turkey), where my primary interest during my degree was manufacturing. During a visit to a center in the university, I came across a 3D printer that was printing inert materials for fabrication of 3D objects, specifically plaster. It was fascinating because it was my first time seeing complex structures being manufactured. So, this sparked my interest to move into 3D printing research, and so I applied for PhD at the University at Buffalo, New York.At the time, the lab that I joined just started tissue engineering work. Combining 3D printing with tissue engineering, we then started bioprinting research there. After completing my PhD, I joined The University of Iowa as an assistant professor, where I established my independent lab and started my career as an independent researcher. We began working on various aspects of bioprinting, developing innovations there including co-axial bioprinting technology which has been translated into the market now. Then in 2015, I joined The Pennsylvania State University.You recently created a 3D-printed breast cancer tumor model. Could you tell us a bit more about this?One of the application areas of bioprinting technologies in our lab is building 3D tissue models, such as cancer. Our primary area of interest lies in breast cancer and understanding how the ca","PeriodicalId":73578,"journal":{"name":"Journal of 3D printing in medicine","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135969105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of laser power ratios on sinterability and physical properties of 3D prototypes sintered using selective laser sintering","authors":"Twinkle Gharate, Tukaram Karanwad, Srushti Lekurwale, Subham Banerjee","doi":"10.2217/3dp-2023-0007","DOIUrl":"https://doi.org/10.2217/3dp-2023-0007","url":null,"abstract":"Aim: This study was intended to investigate the effect of laser power ratios (LPRs) on the sinterability and sintering performance of selective laser sintering (SLS) mediated 3D prototypes. Materials & methods: Physical mixtures (PMs) containing Kollidon SR (98.75% w/w) and IR-absorbing dye (1.25% w/w) were evaluated for flow characteristics and particle size. The same PMs were subjected to SLS-mediated prototyping at constant printing temperatures (feed bed temperature 30°C and print bed temperature 40°C) over a range of LPRs. Results & conclusion: With favoured particle size and flow properties, this PMs was found to be suitable for SLS-mediated 3D printing. Sinterability and sintering performance were improved incrementally throughout the range of studied LPRs. The best sintering performance in terms of dimensional accuracy and printing yield was achieved at the highest LPR (3.0). Scanning electron microscopy (SEM) depicted topography of cross-sectioned sintered printlets.","PeriodicalId":73578,"journal":{"name":"Journal of 3D printing in medicine","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136060802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of a 3D printed, color-coded airway model for bronchoscopy training and anatomy learning","authors":"Christopher T Leba, S. Vydro, Scott Drapeau, D. Romero, D. Harmon, M. Norris, Alyssa Perez, Michael J. Bunker, Shafkat Anwar, J. Sewell","doi":"10.2217/3dp-2023-0005","DOIUrl":"https://doi.org/10.2217/3dp-2023-0005","url":null,"abstract":"Aim: Tracheobronchial anatomy for bronchoscopy education is challenging. 3D printing (3DP) is a promising technology to design bronchoscopy simulators. Materials & m ethods: We created a 3DP tracheobronchial model and color-coded the airways to train first-year pulmonary fellows. A pre- and post-test, practical test and post-test questionnaires were used to evaluate the curriculum implementation. Results: For six fellows the pre- and post-test mean score improved from 11.5/22 (SD = ±1.71) to 16.2/22 (SD = ±2.79). Practical testing mean was 34.5/54 (SD = ±5.82). Questionnaires rated the 3DP model favorably. Conclusion: Our pilot curriculum using a color-coded 3DP model demonstrated improvement in airway identification with favorable ratings by fellows. We posit conceptual frameworks in play and how we address them in future models.","PeriodicalId":73578,"journal":{"name":"Journal of 3D printing in medicine","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74460773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A 3D-printed phantom twin and multi-transducer holder for dynamic anatomical ultrasonography of the lower limb","authors":"C. Langton, Antonio Grimm, D. Lloyd, L. Frossard","doi":"10.2217/3dp-2023-0004","DOIUrl":"https://doi.org/10.2217/3dp-2023-0004","url":null,"abstract":"We aim to improve the residuum health of individuals suffering from lower-limb loss through ‘digital twin’ computational simulations for the creation of optimized 3D-printed prosthetic attachments. Our objective is to utilize 4D tracking data of various tissue interfaces as a primary input into the digital twin. Dynamic anatomical ultrasonography (DAU) is a novel technique in which synchronized individual transducers are positioned at known locations utilizing a 3D-printed holder. Pulse-echo ultrasound data are recorded and subsequently analyzed, providing plots of tissue interface depths versus recording time. For the scientific validation of the DAU technique, a bespoke 3D-printed phantom twin has been created incorporating replica compartments of soft-tissue interfaces and bone tissue of a healthy thigh. To demonstrate its utility, a preliminary experiment was performed in which the phantom twin was positioned within the DAU device and the replica bone manually traversed randomly; subsequent DAU analysis provided a plot of interface depth versus recording time.","PeriodicalId":73578,"journal":{"name":"Journal of 3D printing in medicine","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77593752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"3D bioprinting: challenges in commercialization and clinical translation","authors":"S. Vijayavenkataraman","doi":"10.2217/3dp-2022-0026","DOIUrl":"https://doi.org/10.2217/3dp-2022-0026","url":null,"abstract":"3D Bioprinting has become a revolutionary tool in the field of tissue engineering and regenerative medicine. Bioprinting industry has seen a tremendous growth in the past decade, with a number of bioink companies and bioprinter companies on the rise. While the growth of bioprinting has been tremendous in terms of research and reach, permeating into life sciences research where two-dimensional cell culture has been the norm, we are yet to witness a commercial success in terms of clinical translation. This perspective article aims to highlight some of the lesser-discussed challenges in the field that are to be overcome to fully translate the use of bioprinting into the clinics and make it a standard of testing in the pharmaceuticals industry.","PeriodicalId":73578,"journal":{"name":"Journal of 3D printing in medicine","volume":"109 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90747621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of 3D printing on oral and maxillofacial surgery","authors":"H. Hadad, Fernanda Bdj Boos Lima, I. Shirinbak, T. Porto, Jason E Chen, F. Guastaldi","doi":"10.2217/3dp-2022-0025","DOIUrl":"https://doi.org/10.2217/3dp-2022-0025","url":null,"abstract":"3D printing technology has driven major medical, dental, engineering, and education innovations. In oral and maxillofacial surgery (OMFS), 3D printing technology has been implemented to improve precision in treatment planning, increase surgical predictability, reduce operation times, and lower overall costs. Furthermore, 3D printing has opened access to surgical training, facilitated patient-physician relationships, and generated greater surgical outcomes. The aim of this review is to summarize the impact of 3D printing technology in the field of OMFS. We discuss its many applications in the management of maxillofacial trauma and reconstruction, orthognathic surgery, maxillofacial prosthodontics, temporomandibular joint (TMJ) reconstruction, dental implants (3D-printed surgical guides and 3D-printed dental implants), bone tissue engineering for maxillofacial regeneration, clinical education, and patient communication.","PeriodicalId":73578,"journal":{"name":"Journal of 3D printing in medicine","volume":"60 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78240344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of post-infarct ventricular septal defects through 3D printing and statistical shape analysis.","authors":"Ashar Asif,&nbsp;Andrew Iu Shearn,&nbsp;Mark S Turner,&nbsp;Maria V Ordoñez,&nbsp;Froso Sophocleous,&nbsp;Ana Mendez-Santos,&nbsp;Israel Valverde,&nbsp;Gianni D Angelini,&nbsp;Massimo Caputo,&nbsp;Mark Ck Hamilton,&nbsp;Giovanni Biglino","doi":"10.2217/3dp-2022-0012","DOIUrl":"https://doi.org/10.2217/3dp-2022-0012","url":null,"abstract":"<p><strong>Background: </strong>Post-infarct ventricular septal defect (PIVSD) is a serious complication of myocardial infarction. We evaluated 3D-printing models in PIVSD clinical assessment and the feasibility of statistical shape modeling for morphological analysis of the defects.</p><p><strong>Methods: </strong>Models (n = 15) reconstructed from computed tomography data were evaluated by clinicians (n = 8). Statistical shape modeling was performed on 3D meshes to calculate the mean morphological configuration of the defects.</p><p><strong>Results: </strong>Clinicians' evaluation highlighted the models' utility in displaying defects for interventional/surgical planning, education/training and device development. However, models lack dynamic representation. Morphological analysis was feasible and revealed oval-shaped (n = 12) and complex channel-like (n = 3) defects.</p><p><strong>Conclusion: </strong>3D-PIVSD models can complement imaging data for teaching and procedural planning. Statistical shape modeling is feasible in this scenario.</p>","PeriodicalId":73578,"journal":{"name":"Journal of 3D printing in medicine","volume":"7 1","pages":"3DP3"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9990116/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9104717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How is point-of-care 3D printing influencing medical device innovation? A survey on an Australian public healthcare precinct","authors":"Mathilde R. Desselle, M. Wagels, M. Chamorro-Koc, G. Caldwell","doi":"10.2217/3dp-2022-0024","DOIUrl":"https://doi.org/10.2217/3dp-2022-0024","url":null,"abstract":"Aim: To understand the role point-of-care 3D printing is playing in medical device innovation, to articulate tangible and intangible benefits of open social innovation models with internal and external stakeholders, and to identify key considerations to support implementation of 3D printing in public hospitals. Method: Survey on an Australian public health precinct (n = 68). Results: 3D printing influences organizational culture and how users navigate the regulatory framework. Access to on-site 3D printing technology stimulates collaboration and rapid design cycles. Open innovation approaches can help reconcile motivations, as well as social and economic benefits. Staff training, engagement with regulatory reforms and a recalibration of the scope of impact that design thinking can have on medical device innovation projects are needed.","PeriodicalId":73578,"journal":{"name":"Journal of 3D printing in medicine","volume":"104 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91311144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}