JMM case reports最新文献_第2页

Corrigendum: Optic neuropathy and congenital glaucoma associated with probable Zika virus infection in Venezuelan patients. 勘误:委内瑞拉患者视神经病变和先天性青光眼可能与寨卡病毒感染相关。

JMM case reports Pub Date : 2018-08-31 eCollection Date: 2018-08-01 DOI: 10.1099/jmmcr.0.005161

C Gustavo De Moraes, Michele Pettito, Juan B Yepez, Anavaj Sakuntabhai, Etienne Simon-Loriere, Mussaret B Zaidi, Matthieu Prot, Claude Ruffie, Susan S Kim, Rando Allikmets, Joseph D Terwilliger, Joseph H Lee, Gladys E Maestre

引用次数: 2

Guillain Barré syndrome associated with bladder instillation of Bacille Calmette Guérin (BCG). 膀胱灌注卡介苗(BCG)相关的格林-巴氏综合征。

JMM case reports Pub Date : 2018-08-20 eCollection Date: 2018-08-01 DOI: 10.1099/jmmcr.0.005164

Karmel Webb, Pradhib Venkatesan

{"title":"Guillain Barré syndrome associated with bladder instillation of Bacille Calmette Guérin (BCG).","authors":"Karmel Webb, Pradhib Venkatesan","doi":"10.1099/jmmcr.0.005164","DOIUrl":"https://doi.org/10.1099/jmmcr.0.005164","url":null,"abstract":"Introduction: Guillain Barré Syndrome (GBS) has rarely been associated with tuberculosis and has been previously reported after Bacille Calmette Guérin (BCG) vaccination, but we report an association of GBS with intra-vesical BCG instillations followed by the clinical picture of disseminated BCGosis.Case presentation: A 68-year-old man with bladder carcinoma had a transurethral tumour resection followed by repeated BCG instillations. Catheterization for his eighth dose was traumatic, causing frank haematuria. Ten days later he presented with fevers, myalgia and dyspnoea. Chest X-ray on admission showed micronodular shadowing and a computed tomography scan showed miliary changes in the lungs. Disseminated BCGosis infection was suspected and his symptoms did improve after starting rifamipicin, isoniazid and ethambutol. Over 2 weeks post-admission he developed an unsteady gait, reduced pin-prick sensation below both knees and fingertips, reduced proprioception in both toes and ankles, with absent reflexes in his lower limbs and diminished reflexes in his upper limbs. Nerve conduction studies showed a purely demyelinating sensori-motor peripheral neuropathy in upper and lower limbs, characteristic of GBS.Conclusion: To our knowledge this is the first case report of GBS following bladder instillation of BCG. Given the millions of cases of tuberculosis and millions of doses of administered BCG, GBS must be a very rare adverse effect.","PeriodicalId":73559,"journal":{"name":"JMM case reports","volume":"5 8","pages":"e005164"},"PeriodicalIF":0.0,"publicationDate":"2018-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1099/jmmcr.0.005164","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36630210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Measles during arbovirus outbreak: a diagnostic challenge. 虫媒病毒暴发期间的麻疹:诊断挑战。

JMM case reports Pub Date : 2018-08-10 eCollection Date: 2018-08-01 DOI: 10.1099/jmmcr.0.005156

Ann-Claire Gourinat, Cécile Cazorla, Anne Pfannstiel, Thomas Tran

{"title":"Measles during arbovirus outbreak: a diagnostic challenge.","authors":"Ann-Claire Gourinat, Cécile Cazorla, Anne Pfannstiel, Thomas Tran","doi":"10.1099/jmmcr.0.005156","DOIUrl":"https://doi.org/10.1099/jmmcr.0.005156","url":null,"abstract":"Introduction. Dengue fever is a major public health problem in New Caledonia, like in many Pacific Islands Countries and territories. In 2017 New Caledonia faced multiple circulations of arboviruses with a major outbreak of dengue and a co-circulating Zika virus. New Caledonia is considered as a non-endemic territory for measles since the mid 1990’s. Case presentation. A 41-year-old male presented fever, headache, sinusitis and exanthematous maculopapular rash. A clinical diagnosis of arbovirus was first suspected due to the local epidemic context. A few days later the patient was admitted to the main hospital. The real time RT-PCR for dengue and Zika virus were negative on the first blood sample. A drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome and other infectious diseases including measles were then suspected. ELISA tests for measles were positive for IgM and equivocal for IgG. A throat swab was immediately shipped to a reference laboratory for measles nucleic acid testing. After a week, the patient recovered and the presence of measles RNA was confirmed. No secondary cases were reported among contacts of the patient and the source of his infection could not be ascertained. Conclusion. Diagnosis of measles during an arbovirus outbreak in a country where measles disease is rare can be a pitfall for healthcare professionals. The introduction of measles via returned travellers or tourists from areas where measles remains endemic is a real threat to countries with high vaccine coverage.","PeriodicalId":73559,"journal":{"name":"JMM case reports","volume":"5 8","pages":"e005156"},"PeriodicalIF":0.0,"publicationDate":"2018-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152402/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36587035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Rare Elizabethkingia anophelis meningitis case in a Danish male. 丹麦男性罕见伊丽莎白按蚊脑膜炎病例。

JMM case reports Pub Date : 2018-08-09 eCollection Date: 2018-08-01 DOI: 10.1099/jmmcr.0.005163

Hans Linde Nielsen, Irene Harder Tarpgaard, David Fuglsang-Damgaard, Philip Kjettinge Thomsen, Sylvain Brisse, Michael Dalager-Pedersen

{"title":"Rare Elizabethkingia anophelis meningitis case in a Danish male.","authors":"Hans Linde Nielsen, Irene Harder Tarpgaard, David Fuglsang-Damgaard, Philip Kjettinge Thomsen, Sylvain Brisse, Michael Dalager-Pedersen","doi":"10.1099/jmmcr.0.005163","DOIUrl":"https://doi.org/10.1099/jmmcr.0.005163","url":null,"abstract":"Introduction: Elizabethkingia anophelis is a Gram-negative, aerobic, non-motile rod belonging to the family Flavobacteriaceae. Over the last 5 years, it has emerged as an opportunistic human pathogen involved in neonatal meningitis and sepsis, as well as nosocomial outbreaks. It has been isolated from the midgut of the Anopheles gambiae mosquito, but there is no evidence for a role of the mosquito in human infections, and very little is known regarding the routes of transmission to humans. Recent studies, primarily from South-East Asia, suggest that E. anophelis, and not Elizabethkingia meningoseptica, is the predominant human pathogen of this genus. However, identification to the species level has been difficult due to the limitations of the current MALDI-TOF MS (matrix-associated laser desorption ionization-time of flight MS) systems for correct species identification.Case presentation: Here, we present a rare case of E. anophelis meningitis in a Danish male, who had a travel exposure to Malaysia 7 weeks before hospitalization. A multidrug-resistant Elizabethkingia species was isolated from blood and cerebrospinal fluid, and genomic sequencing was used to characterize the phylogenetic position of the isolate, which was determined as associated with previously described sublineage 11. The patient was successfully treated with intravenous moxifloxacin and rifampicin for 2 weeks with no major sequelae, but we did not find the source of transmission.Conclusion: All clinical microbiologists should be aware of the present limitations of the MALDI-TOF MS systems for correct species identification, and therefore we recommend the use of genome sequencing for the correct identification at the species and sublineage level.","PeriodicalId":73559,"journal":{"name":"JMM case reports","volume":"5 8","pages":"e005163"},"PeriodicalIF":0.0,"publicationDate":"2018-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152398/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36630209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13

Ehrlichiosis presenting as severe sepsis and meningoencephalitis in an immunocompetent adult. 埃立克体病表现为严重败血症和脑膜脑炎在免疫能力的成年人。

JMM case reports Pub Date : 2018-07-27 eCollection Date: 2018-09-01 DOI: 10.1099/jmmcr.0.005162

Stephanie L Buzzard, Brittany D Bissell, Melissa L Thompson Bastin

{"title":"Ehrlichiosis presenting as severe sepsis and meningoencephalitis in an immunocompetent adult.","authors":"Stephanie L Buzzard, Brittany D Bissell, Melissa L Thompson Bastin","doi":"10.1099/jmmcr.0.005162","DOIUrl":"https://doi.org/10.1099/jmmcr.0.005162","url":null,"abstract":"Introduction: Ehrlichia are obligate intracellular pathogens transmitted to vertebrates by ticks.Case presentation: We report the case of a 59-year-old man who presented to the University of Kentucky Albert B. Chandler Medical Center (Lexington, KY, USA) after being found fallen down in the woods. A lumbar puncture revealed what appeared to be bacterial meningitis, yet cerebrospinal fluid cultures, Gram stains and a meningitis/encephalitis panel were inconclusive. However, an Ehrlichia DNA PCR of the blood resulted as being positive for Ehrlichia chaffeensis antibodies. The patient received a 14 day course of doxycycline, and recovered from his multiple organ failure. The aetiology of the ehrlichial meningoencephalitis was likely transmission through a tick-bite, due to the patient's outdoor exposure.Conclusion: While it is rare to see Ehrlichia as a cause of meningitis, this illness can progress to severe multisystem disease with septic shock, meningoencephalitis or acute respiratory distress syndrome (ARDS). Those with compromised immunity are at a higher risk of developing the more severe form of the disease and have higher case fatality rates.","PeriodicalId":73559,"journal":{"name":"JMM case reports","volume":"5 9","pages":"e005162"},"PeriodicalIF":0.0,"publicationDate":"2018-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230758/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36676335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

A case of hepato-biliary infection secondary to cryptosporidium in a patient on tacrolimus. 他克莫司致隐孢子虫继发肝胆感染1例。

JMM case reports Pub Date : 2018-07-20 eCollection Date: 2018-08-01 DOI: 10.1099/jmmcr.0.005159

Sajal Gupta, Alison Johnson, Simon Meyrick, Angharad P Davies, R Chalmers

{"title":"A case of hepato-biliary infection secondary to cryptosporidium in a patient on tacrolimus.","authors":"Sajal Gupta, Alison Johnson, Simon Meyrick, Angharad P Davies, R Chalmers","doi":"10.1099/jmmcr.0.005159","DOIUrl":"https://doi.org/10.1099/jmmcr.0.005159","url":null,"abstract":"Introduction: Cryptosporidium infection is known to cause hepato-biliary involvement, mainly in association with T-cell immune deficiency. Hepato-biliary involvement in association with milder immunosuppression is less well described. We describe the first case, to our knowledge, of Cryptosporidium hominis hepato-biliary infection associated with tacrolimus in a patient with nephrotic syndrome.Case presentation: A 14 year old girl who had been on tacrolimus for nephrotic syndrome presented with diarrhea due to C. hominis. Nineteen days after her initial presentation she attended hospital with abdominal pain and deranged liver function tests. An ultrasound scan showed a thickened gall bladder. Her symptoms settled and her liver function tests returned to normal after treatment with nitazoxanide.Conclusion: Cryptosporidium should be considered in the differential diagnosis of both diarrhea and hepato-biliary symptoms and abnormal liver function tests, even in the presence of relatively mild immunosuppression. Nitazoxanide was an effective treatment in this case.","PeriodicalId":73559,"journal":{"name":"JMM case reports","volume":"5 8","pages":"e005159"},"PeriodicalIF":0.0,"publicationDate":"2018-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152403/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36587036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Cyberlindnera jadinii (teleomorph Candida utilis) candidaemia in a patient with aplastic anaemia: a case report. 再生障碍性贫血患者念珠菌血症1例报告。

JMM case reports Pub Date : 2018-07-10 eCollection Date: 2018-08-01 DOI: 10.1099/jmmcr.0.005160

Pauline Treguier, Marion David, Gilles Gargala, Vincent Camus, Aspasia Stamatoullas, Anne-Lise Menard, Pascal Lenain, Nathalie Contentin, Emilie Lemasle, Helene Lanic, Hervé Tilly, Fabrice Jardin, Stéphane Lepretre

{"title":"Cyberlindnera jadinii (teleomorph Candida utilis) candidaemia in a patient with aplastic anaemia: a case report.","authors":"Pauline Treguier, Marion David, Gilles Gargala, Vincent Camus, Aspasia Stamatoullas, Anne-Lise Menard, Pascal Lenain, Nathalie Contentin, Emilie Lemasle, Helene Lanic, Hervé Tilly, Fabrice Jardin, Stéphane Lepretre","doi":"10.1099/jmmcr.0.005160","DOIUrl":"https://doi.org/10.1099/jmmcr.0.005160","url":null,"abstract":"Introduction: We present what is believed to be the first report of candidaemia caused by Cyberlindnera (Pichia) jadinii (teleomorph of Candida utilis) in a patient with an aplastic anaemia.Case presentation: The patient, a 21-year-old male, presented with hepatic cytolysis, cutaneous and pulmonary involvement, and septic shock. Cyberlindnera jadinii was identified by aerobic blood culture and MS. The patient initially received multiple and combined antifungal therapy, but continued to have persistent skin lesions and fever. He was successfully treated by emergency haploidentical haematopoietic stem cell transplantation, combined with triple antifungal therapy and supportive care.Conclusion: Cyberlindnera jadinii, teleomorph of Candida utilis, which is not usually invasive, can lead to an opportunistic invasive infection in unhealthy adult patients. For treatment of the invasive candida infection, it is necessary to combine antifungal therapy and supportive care.","PeriodicalId":73559,"journal":{"name":"JMM case reports","volume":"5 8","pages":"e005160"},"PeriodicalIF":0.0,"publicationDate":"2018-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152400/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36587037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Staphylococcus haemolyticus epididymo-orchitis and bacteraemia: a case report. 附睾-睾丸炎溶血葡萄球菌合并菌血症1例。

JMM case reports Pub Date : 2018-07-05 eCollection Date: 2018-07-01 DOI: 10.1099/jmmcr.0.005157

Christina Pindar, Roberto A Viau

引用次数: 7

Mycobacterium xenopi systemic infection in a domestic fiery-shouldered conure bird (Pyrrhura egregia). 家养赤肩野禽的异种分枝杆菌全身感染。

JMM case reports Pub Date : 2018-07-04 eCollection Date: 2018-07-01 DOI: 10.1099/jmmcr.0.005158

Guillaume St-Jean, Carl A Gagnon, Hafid Soualhine, Manon Tremblay, Andrée-Anne Beaulieu, Doris Sylvestre

{"title":"Mycobacterium xenopi systemic infection in a domestic fiery-shouldered conure bird (Pyrrhura egregia).","authors":"Guillaume St-Jean, Carl A Gagnon, Hafid Soualhine, Manon Tremblay, Andrée-Anne Beaulieu, Doris Sylvestre","doi":"10.1099/jmmcr.0.005158","DOIUrl":"https://doi.org/10.1099/jmmcr.0.005158","url":null,"abstract":"Introduction: Mycobacterium xenopi is a rare opportunistic pathogen mainly causing infections in immunocompromised human patients or those with underlying chronic structural lung disease. Cases of disease in veterinary medicine remain scarce. Few animal species, including birds, are suspected of being vectors of the disease and there has not yet been a report of clinical disease in birds. We report the first case, to our knowledge, of systemic infection in a domestic bird.Case presentation: A female fiery-shouldered conure was submitted after death for necropsy following episodes of heavy breathing. The necropsy revealed multiple granulomatous lesions within the liver, air sacs and kidneys. Ziehl-Neelsen stains demonstrated the presence of numerous intralesional acid-fast bacilli. PCR assays and culture confirmed the presence of M. xenopi.Conclusion: Through this case we hope to describe the characteristics of M. xenopi disease in birds and the possible close relationship between animal and human infections.","PeriodicalId":73559,"journal":{"name":"JMM case reports","volume":"5 7","pages":"e005158"},"PeriodicalIF":0.0,"publicationDate":"2018-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159546/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36546543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Extensively drug-resistant (XDR) Pseudomonas aeruginosa identified in Lima, Peru co-expressing a VIM-2 metallo-β-lactamase, OXA-1 β-lactamase and GES-1 extended-spectrum β-lactamase. 广泛耐药(XDR)铜绿假单胞菌在秘鲁利马共表达一种VIM-2金属β-内酰胺酶、OXA-1 β-内酰胺酶和GES-1广谱β-内酰胺酶。

JMM case reports Pub Date : 2018-06-21 eCollection Date: 2018-07-01 DOI: 10.1099/jmmcr.0.005154

Paul Ríos, Claudio Rocha, William Castro, Maria Vidal, Enrique Canal, Manuela Bernal, Nathanael D Reynolds, Drake H Tilley, Mark P Simons

{"title":"Extensively drug-resistant (XDR) Pseudomonas aeruginosa identified in Lima, Peru co-expressing a VIM-2 metallo-β-lactamase, OXA-1 β-lactamase and GES-1 extended-spectrum β-lactamase.","authors":"Paul Ríos, Claudio Rocha, William Castro, Maria Vidal, Enrique Canal, Manuela Bernal, Nathanael D Reynolds, Drake H Tilley, Mark P Simons","doi":"10.1099/jmmcr.0.005154","DOIUrl":"https://doi.org/10.1099/jmmcr.0.005154","url":null,"abstract":"Introduction: Pseudomonas aeruginosa has the ability to acquire plasmids and other mobile genetic elements that confer resistance to antibiotics. Bacterial genes encoding different β-lactamases (bla), such as metallo-β-lactamases (MBLs) and extended-spectrum β-lactamases (ESBL), can confer resistance to multiple classes of β-lactam antibiotics.Case presentation: An 83 year old female was admitted in 2012 to the Peruvian Naval Hospital, Centro Médico Naval 'Cirujano Mayor Santiago Távara' (CEMENA), in Lima, Peru. A midstream urine sample was collected and sent to the local CEMENA laboratory for routine urine culture. P. aeruginosa was isolated and initial antibiotic susceptibility testing showed it to be sensitive to imipenem. The clinicians started a course of meropenem, but the patient did not improve. After 5 days, a second urine culture was performed and a P. aeruginosa was isolated again, but this time the strain showed resistance to imipenem. The treatment course was changed to fosfomycin and the patient improved. Phenotypic and molecular laboratory testing to characterize the antibiotic resistance were performed, demonstrating the presence of both MBL and ESBL genes.Conclusion: To our knowledge, this is the first report of a P. aeruginosa XDR clinical isolate that co-expresses an MBL (VIM-2), OXA-1 beta-lactamase and the ESBL (GES-1) in Peru. It is also the first report of a VIM carbapenemase in Peru.","PeriodicalId":73559,"journal":{"name":"JMM case reports","volume":"5 7","pages":"e005154"},"PeriodicalIF":0.0,"publicationDate":"2018-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159545/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36546541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9