JMM case reports最新文献

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Liver abscess caused by Gram-negative spiral bacilli. 革兰氏阴性螺旋杆菌所致肝脓肿。
JMM case reports Pub Date : 2018-06-08 eCollection Date: 2018-07-01 DOI: 10.1099/jmmcr.0.005155
Hideharu Hagiya, Keigo Kimura, Isao Nishi, Kazunori Tomono
{"title":"Liver abscess caused by Gram-negative spiral bacilli.","authors":"Hideharu Hagiya, Keigo Kimura, Isao Nishi, Kazunori Tomono","doi":"10.1099/jmmcr.0.005155","DOIUrl":"https://doi.org/10.1099/jmmcr.0.005155","url":null,"abstract":"A man in his eighties presenting high fever accompanying right flank pain visited us. He had had an episode of several weeks of diarrhoea a month previously. Laboratory analysis showed an elevation of serum C-reactive protein (9.55mg dl ), and enhanced computed tomography showed a hepatic mass suggesting liver abscess (Fig. 1a). Pus was drained through percutaneous paracentesis, and Gram staining of the purulent material was performed (Fig. 1b).","PeriodicalId":73559,"journal":{"name":"JMM case reports","volume":"5 7","pages":"e005155"},"PeriodicalIF":0.0,"publicationDate":"2018-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159544/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36546540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
A case of NDM-carbapenemase-producing hypervirulent Klebsiella pneumoniae sequence type 23 from the UK. 英国产ndm -碳青霉烯酶高致病性肺炎克雷伯菌序列23例。
JMM case reports Pub Date : 2018-05-17 eCollection Date: 2018-09-01 DOI: 10.1099/jmmcr.0.005130
Kerry J Roulston, Tehmina Bharucha, Jane F Turton, Katie L Hopkins, Damien J F Mack
{"title":"A case of NDM-carbapenemase-producing hypervirulent <i>Klebsiella pneumoniae</i> sequence type 23 from the UK.","authors":"Kerry J Roulston,&nbsp;Tehmina Bharucha,&nbsp;Jane F Turton,&nbsp;Katie L Hopkins,&nbsp;Damien J F Mack","doi":"10.1099/jmmcr.0.005130","DOIUrl":"https://doi.org/10.1099/jmmcr.0.005130","url":null,"abstract":"<p><strong>Introduction: </strong>Hypervirulent capsular type K1 <i>Klebsiella pneumoniae</i> strains of clonal complex 23 (CC23) are associated with severe community-acquired pyogenic liver abscesses, often complicated by metastatic infections and significant mortality. The majority of hypervirulent strains reported are susceptible to most antibiotics except ampicillin. To the best of our knowledge, this is the first case of New Delhi metallo-β-lactamase (<i>bla</i> <sub>NDM</sub>)-producing hypervirulent <i>K. pneumoniae</i> from the UK.</p><p><strong>Case presentation: </strong>We present a case of pyogenic liver abscess in a 63-year-old female of Bangladeshi origin, with a recent diagnosis of pancreatic cancer. The patient was treated with piperacillin/tazobactam and blood cultures grew a fully susceptible <i>Escherichia coli.</i> Despite antimicrobial therapy and drainage of the abscess, the patient continued to deteriorate and died on day seven of admission. The fluid drained from the liver abscess grew a fully susceptible <i>E. coli</i> and a multi-drug-resistant <i>K. pneumoniae</i>. Two weeks prior to admission, a rectal screening swab grew a metallo-β-lactamase-producing <i>K. pneumoniae</i>. Molecular characterization revealed that both the <i>K. pneumoniae</i> isolates belonged to the hypervirulent K1 cluster of CC23, sequence type 23. The isolate from the rectal screen was positive for the <i>bla</i> <sub>NDM</sub> metallo-β-lactamase gene.</p><p><strong>Conclusion: </strong>The emergence of carbapenemase-producing hypervirulent <i>K. pneumoniae</i> strains presents a new and significant threat to global public health. Management of these infections will be extremely challenging due to the limited treatment options available and they are likely to be associated with an even greater mortality.</p>","PeriodicalId":73559,"journal":{"name":"JMM case reports","volume":"5 9","pages":"e005130"},"PeriodicalIF":0.0,"publicationDate":"2018-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230755/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36722109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 31
Non-congenital severe ocular complications of Zika virus infection. 寨卡病毒感染的非先天性严重眼部并发症。
JMM case reports Pub Date : 2018-05-14 eCollection Date: 2018-06-01 DOI: 10.1099/jmmcr.0.005152
Mussaret B Zaidi, C Gustavo De Moraes, Michele Petitto, Juan B Yepez, Anavaj Sakuntabhai, Etienne Simon-Loriere, Matthieu Prot, Claude Ruffie, Susan S Kim, Rando Allikmets, Joseph D Terwilliger, Joseph H Lee, Gladys E Maestre
{"title":"Non-congenital severe ocular complications of Zika virus infection.","authors":"Mussaret B Zaidi,&nbsp;C Gustavo De Moraes,&nbsp;Michele Petitto,&nbsp;Juan B Yepez,&nbsp;Anavaj Sakuntabhai,&nbsp;Etienne Simon-Loriere,&nbsp;Matthieu Prot,&nbsp;Claude Ruffie,&nbsp;Susan S Kim,&nbsp;Rando Allikmets,&nbsp;Joseph D Terwilliger,&nbsp;Joseph H Lee,&nbsp;Gladys E Maestre","doi":"10.1099/jmmcr.0.005152","DOIUrl":"https://doi.org/10.1099/jmmcr.0.005152","url":null,"abstract":"HAL is a multi-disciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not. The documents may come from teaching and research institutions in France or abroad, or from public or private research centers. L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignement et de recherche français ou étrangers, des laboratoires publics ou privés.","PeriodicalId":73559,"journal":{"name":"JMM case reports","volume":"5 6","pages":"e005152"},"PeriodicalIF":0.0,"publicationDate":"2018-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096927/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36414724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
Salmonella enterica serovar Typhimurium isolated from the urine of a dog undergoing treatment for immune-mediated polyarthritis. 从一只接受免疫介导的多关节炎治疗的狗的尿液中分离出伤寒沙门氏菌。
JMM case reports Pub Date : 2018-05-08 eCollection Date: 2018-09-01 DOI: 10.1099/jmmcr.0.005153
Stephen D Cole, Shannon M Palermo, Shelley C Rankin
{"title":"<i>Salmonella enterica</i> serovar Typhimurium isolated from the urine of a dog undergoing treatment for immune-mediated polyarthritis.","authors":"Stephen D Cole, Shannon M Palermo, Shelley C Rankin","doi":"10.1099/jmmcr.0.005153","DOIUrl":"10.1099/jmmcr.0.005153","url":null,"abstract":"<p><strong>Introduction: </strong>In people, <i>Salmonella</i> is a common agent of gastroenteritis, but it can also cause extraintestinal disease such as urinary tract infections. In addition, <i>Salmonella</i> is often linked to the post-infection development of reactive arthritis. In canines, cases that document extraintestinal <i>Salmonella</i> infections or diseases similar to reactive arthritis have not been thoroughly described.</p><p><strong>Case presentation: </strong>A case of a 5-year-old German shepherd dog with <i>Salmonella</i> bacteriuria during treatment for immune-mediated polyarthritis (IMPA) is described. The patient first suffered from a 3 month period of diarrhoea and presented for evaluation of a 2 month history of shifting-leg lameness. A diagnosis of IMPA was made based on cytological examination and negative synovial fluid culture. Treatment with immunosuppressive doses of prednisone lead to clinical resolution of lameness, but on a recheck abnormal urine was noted. <i>Salmonella enterica</i> serovar Typhimurium was isolated using standard culture methods. The patient was treated with enrofloxacin to control the bacteriuria.</p><p><strong>Conclusion: </strong>This case report is, to the best of our knowledge, the first to describe <i>Salmonella</i> bacteriuria in a dog and suggests that <i>Salmonella</i> infection may be a potential inciting factor for IMPA.</p>","PeriodicalId":73559,"journal":{"name":"JMM case reports","volume":"5 9","pages":"e005153"},"PeriodicalIF":0.0,"publicationDate":"2018-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230761/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36676334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Corneal abscess due to Moraxella nonliquefaciens. 非液化莫拉菌引起的角膜脓肿。
JMM case reports Pub Date : 2018-04-20 eCollection Date: 2018-06-01 DOI: 10.1099/jmmcr.0.005150
Fernando Cobo, Javier Rodríguez-Granger, Antonio Sampedro, José María Navarro-Marí
{"title":"Corneal abscess due to <i>Moraxella nonliquefaciens</i>.","authors":"Fernando Cobo,&nbsp;Javier Rodríguez-Granger,&nbsp;Antonio Sampedro,&nbsp;José María Navarro-Marí","doi":"10.1099/jmmcr.0.005150","DOIUrl":"https://doi.org/10.1099/jmmcr.0.005150","url":null,"abstract":"A 71-year-old man was seen due to red eye along with loss of vision in the right eye. The patient only referred to a whitish spot on the corneal surface over 3months probably due to a strange body, but no antimicrobial treatment was started at this stage. Physical examination revealed a central corneal infiltrate in almost all the corneal thickness, an overlying epithelial defect, and a moderate corneal oedema without hypopyon. Several corneal biopsies were taken, and they were directly inoculated to aerobic blood agar (Columbia Agar 5% Sheepblood, Becton Dickinson), chocolate agar (Choco Agar, Becton Dickinson), Sabouraud agar (Sabouraud Glucose Agar, Becton Dickinson) and thioglycolate broth (Fluid Thioglycollate Medium, Becton Dickinson). All media were incubated at 37 C, except Sabouraud agar, which was incubated at 30 C. A corneal biopsy for study of viruses was also taken, being negative for adenovirus, herpes simplex (1 and 2) and enterovirus (by polymerase chain reaction). Gram staining of the fluid identified scarce Gramnegative rods. On the first day of incubation the growth of abundant colonies of a non-haemolytic and catalaseand oxidase-positive microorganism was reported in pure culture. No other microorganisms were isolated on the primary plates. A mass spectrometry method (Biotyper, Bruker) was employed to identify the strain as Moraxella nonliquefaciens (log score 2.08). The culture in Sabouraud agar was negative after 21 days of incubation.","PeriodicalId":73559,"journal":{"name":"JMM case reports","volume":"5 6","pages":"e005150"},"PeriodicalIF":0.0,"publicationDate":"2018-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1099/jmmcr.0.005150","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36414722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Sepsis secondary to complicated skin and soft tissue infection caused by Ignatzschineria indica. First case report in Latin America. 印度伊格纳兹氏杆菌致复杂皮肤及软组织感染继发脓毒症。拉丁美洲报告首例病例。
JMM case reports Pub Date : 2018-04-17 eCollection Date: 2018-06-01 DOI: 10.1099/jmmcr.0.005151
Lucía Cipolla, Laura Derdoy, Daniela Archuby, Adriana Tarzia, Francisco Govedic, Mónica Prieto
{"title":"Sepsis secondary to complicated skin and soft tissue infection caused by <i>Ignatzschineria indica</i>. First case report in Latin America.","authors":"Lucía Cipolla,&nbsp;Laura Derdoy,&nbsp;Daniela Archuby,&nbsp;Adriana Tarzia,&nbsp;Francisco Govedic,&nbsp;Mónica Prieto","doi":"10.1099/jmmcr.0.005151","DOIUrl":"https://doi.org/10.1099/jmmcr.0.005151","url":null,"abstract":"<p><strong>Introduction: </strong><i>Ignatzschineria</i> is a recently recognized genus associated with larvae infestation Members of this genus are pathogens infrequently implicated in human disease. During the last decade, fewer than 10 cases of infection with <i>Ignatzchineria</i> species have been reported around the world. Bacteria of the genera <i>Ignatzchineria</i> and <i>Wohlfahrtiimonas</i> have been isolated from larvae of the parasitic fly <i>Wohlfahrtia magnifica</i>, which is found in Europe, Asia and North Africa, and is associated with myiasis in several animal species, but rarely in humans.</p><p><strong>Case presentation: </strong>We report the first case of sepsis associated with complicated skin and soft tissue infection caused by <i>I. indica</i> in Latin America.</p><p><strong>Conclusion: </strong>The clinical and molecular findings in our report add information to the accumulating data on emerging pathogens of this type, their geographic distribution, the correlation between the emergence of infectious diseases and social and economic inequalities, as well as the effects of global climate changes on potentially unusual distribution of vectors. We consider that fly larvae should be regarded as a potential source of specific arthropod-borne bacterial systemic infections.</p>","PeriodicalId":73559,"journal":{"name":"JMM case reports","volume":"5 6","pages":"e005151"},"PeriodicalIF":0.0,"publicationDate":"2018-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096929/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36414723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
Septic cutaneous emboli revealing a severe case of Klebsiella pneumoniae liver abscess syndrome. 脓毒性皮肤栓塞显示肺炎克雷伯菌肝脓肿综合征的严重病例。
JMM case reports Pub Date : 2018-04-12 eCollection Date: 2018-05-01 DOI: 10.1099/jmmcr.0.005148
Florentina Paraschiv, Gabriel Adrian Popescu, Alina Maria Borcan
{"title":"Septic cutaneous emboli revealing a severe case of <i>Klebsiella pneumoniae</i> liver abscess syndrome.","authors":"Florentina Paraschiv,&nbsp;Gabriel Adrian Popescu,&nbsp;Alina Maria Borcan","doi":"10.1099/jmmcr.0.005148","DOIUrl":"https://doi.org/10.1099/jmmcr.0.005148","url":null,"abstract":"<p><strong>Introduction: </strong><i>Klebsiella pneumoniae</i> liver abscess syndrome (KLAS) is characterized by bacteraemia, liver abscesses and metastatic infection caused by a hypervirulent strain of <i>Klebsiella pneumoniae</i>, usually belonging to the capsular serotype K1 or K2. Initially, KLAS was described in Eastern Asia; recently isolated cases have been reported from different parts of the world.</p><p><strong>Case presentation: </strong>We describe the case of a woman with KLAS including meningeal, ocular and cutaneous metastatic infection and organ dysfunctions (coagulation abnormalities, thrombocytopenia and increased creatinine level). The identification of a hypermucoviscous strain of <i>Klebsiella pneumoniae</i> was possible by culture from one of the cutaneous emboli and subsequently confirmed by blood cultures. The patient fully recovered after abscess drainage and prolonged antibiotic treatment.</p><p><strong>Conclusion: </strong>We have pointed out about the importance of sampling each septic focus in order to identify the aetiology of a disseminate infection.</p>","PeriodicalId":73559,"journal":{"name":"JMM case reports","volume":"5 5","pages":"e005148"},"PeriodicalIF":0.0,"publicationDate":"2018-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994707/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36217766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Total nephrectomy following Corynebacterium coyleae urinary tract infection. 肛叶棒状杆菌尿路感染后全肾切除术。
JMM case reports Pub Date : 2018-04-06 eCollection Date: 2018-09-01 DOI: 10.1099/jmmcr.0.005149
Claudia M Barberis, Eduardo Montalvo, Soledad Imas, Germán Traglia, Marisa N Almuzara, Carlos Hernán Rodriguez, Angela Famiglietti, Octavio Mazzocchi, Carlos Vay
{"title":"Total nephrectomy following <i>Corynebacterium coyleae</i> urinary tract infection.","authors":"Claudia M Barberis,&nbsp;Eduardo Montalvo,&nbsp;Soledad Imas,&nbsp;Germán Traglia,&nbsp;Marisa N Almuzara,&nbsp;Carlos Hernán Rodriguez,&nbsp;Angela Famiglietti,&nbsp;Octavio Mazzocchi,&nbsp;Carlos Vay","doi":"10.1099/jmmcr.0.005149","DOIUrl":"https://doi.org/10.1099/jmmcr.0.005149","url":null,"abstract":"<p><strong>Introduction: </strong><i>Corynebacterium coyleae</i> is a Gram-stain-positive non-lipophilic coryneform rod first described in blood samples and pleural fluid. There is scarce information about the clinical relevance of <i>C. coyleae</i> and none on complicated urinary tract infections has been described so far.</p><p><strong>Case presentation: </strong>A 36-year-old woman with a history of chronic kidney failure, under thrice-weekly haemodialysis since 2014 due to polycystic kidney disease, presented with hypogastric pain, lower left quadrant pain and nausea. Since 1997, the patient had developed several episodes of urinary tract infection. On admission, the patient presented tenderness in the lower abdomen and fist positive lumbar percussion. Urine culture showed significant bacterial growth (>10<sup>5</sup> c.f.u. ml<sup>-1</sup>). Slightly glistening colonies of 1 mm in diameter were observed after a 24 h incubation. Gram staining showed coryneform Gram-stain-positive rods. The patient was diagnosed as having a complicated urinary tract infection. A bilateral nephrectomy was performed on the fourth day of hospitalization. Two samples of kidney tissue were sent for culture. Direct examination of the material revealed the presence of abundant inflammatory reaction and Gram-positive diphtheroid rods. The organism was identified using MALDI-TOF and conventional biochemical tests; in both isolates further identification was performed by PCR amplification and sequence analysis of the <i>rpoB</i> gene as <i>Corynebacterium coyleae</i>.</p><p><strong>Conclusions: </strong><i>C. coyleae</i> is an infrequent species among the genus <i>Corynebacterium</i> that should be considered as an emerging pathogen that can be involved in nosocomial infections and complicated urinary tract infections.</p>","PeriodicalId":73559,"journal":{"name":"JMM case reports","volume":"5 9","pages":"e005149"},"PeriodicalIF":0.0,"publicationDate":"2018-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230760/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36722113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Campylobacter fetus prosthetic valve endocarditis presenting as a stroke. 弯曲杆菌胎儿假瓣膜心内膜炎表现为中风。
JMM case reports Pub Date : 2018-04-06 eCollection Date: 2018-05-01 DOI: 10.1099/jmmcr.0.005147
Christina Petridou, Lenka Strakova, Ruan Simpson
{"title":"<i>Campylobacter fetus</i> prosthetic valve endocarditis presenting as a stroke.","authors":"Christina Petridou,&nbsp;Lenka Strakova,&nbsp;Ruan Simpson","doi":"10.1099/jmmcr.0.005147","DOIUrl":"https://doi.org/10.1099/jmmcr.0.005147","url":null,"abstract":"<p><strong>Introduction: </strong><i>Campylobacter</i> is a common pathogen of the gastrointestinal tract, but invasive disease is rare. <i>Campylobacter fetus</i> can play a role in osteomyelitis, meningitis and joint infection and has a prediliction for the vascular endothelium, causing mycotic aneurysms, thrombophlebitis and endocarditis. Here we present a case of prosthetic valve endocarditis caused by <i>C. fetus</i> and a review of the literature.</p><p><strong>Case presentation: </strong>An 85-year-old woman with a tissue aortic valve replacement and atrial fibrillation was admitted to hospital with tonic-clonic seizures, right-sided hemiparesis, facial droop and hemianopia. Multiple cerebral emboli were seen on magnetic resonance imaging of the brain. Blood cultures grew <i>C. fetus</i> and an echocardiogram showed thickening and restricted movement of the aortic valve, a significant difference from an echocardiogram done 2 months before when the same organism was again isolated in blood cultures. She improved after treatment with 6 weeks of amoxicillin and 2 weeks of synergistic gentamicin for prosthetic valve endocarditis.</p><p><strong>Conclusion: </strong>There have only been five previously reported cases of <i>C. fetus</i> prosthetic valve endocarditis and this is the only patient who presented as a stroke. The majority of surviving patients required replacement of the affected valve with only one other patient surviving in the absence of surgery. No guidelines exist on the optimum treatment of <i>C. fetus</i> endocarditis and this case reports adds to the growing literature on the appropriate management for this rare and potentially devastating disease.</p>","PeriodicalId":73559,"journal":{"name":"JMM case reports","volume":"5 5","pages":"e005147"},"PeriodicalIF":0.0,"publicationDate":"2018-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994706/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36217765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
First case report of human infection with Mycobacterium stomatepiae. 首例人感染口腔分枝杆菌病例报告。
JMM case reports Pub Date : 2018-03-22 eCollection Date: 2018-05-01 DOI: 10.1099/jmmcr.0.005146
Jared Weston, Sushil Pandey, Evan Matthews, Evan Bursle
{"title":"First case report of human infection with <i>Mycobacterium stomatepiae</i>.","authors":"Jared Weston,&nbsp;Sushil Pandey,&nbsp;Evan Matthews,&nbsp;Evan Bursle","doi":"10.1099/jmmcr.0.005146","DOIUrl":"https://doi.org/10.1099/jmmcr.0.005146","url":null,"abstract":"<p><strong>Introduction: </strong>We describe the first detailed case report of human infection with <i>Mycobacterium stomatepiae</i>. Infection with non-tuberculous mycobacteria (NTM) related to <i>M. stomatepiae</i> is well described, despite the lack of previous confirmed reports of <i>M. stomatepiae-</i>related human disease. Localised cervical lymphadenitis is the most common NTM disease in children, with species closely related to <i>M. stomatepiae,</i> such as <i>Mycobacterium triplex</i> and <i>Mycobacterium florentinum</i>, having been shown to be rare causative agents.</p><p><strong>Case presentation: </strong>A 19-month-old girl presented with persistent unilateral neck lumps which developed following a facial laceration. Both lumps were fluctuant with overlying erythema and no fistulae present. Incision and drainage with curettage was performed. The operative sample of purulent fluid revealed pleomorphic bacilli on Ziehl-Neelsen staining. The isolate cultured was referred for further genotypic identification via 16S rRNA gene sequencing, identifying the organism as <i>M. stomatepiae</i>.</p><p><strong>Conclusion: </strong>We describe the first detailed case report of human infection with <i>M. stomatepiae.</i> This organism can now be added to the growing list of NTM that are opportunistic human pathogens, though it is likely to remain a very rare causative agent of this clinical syndrome. Early diagnosis relies on clinical suspicion by the treating doctor, flagging potential cases to the microbiology laboratory and hence allowing correct specimen set-up. Laboratory diagnosis requires incubation of cultures at lower temperatures, and definitive identification is best performed by sequencing methods, including 16S rRNA gene sequencing. The description of novel species of NTM causing human disease is likely to increase with further advancements in diagnostic methods.</p>","PeriodicalId":73559,"journal":{"name":"JMM case reports","volume":"5 5","pages":"e005146"},"PeriodicalIF":0.0,"publicationDate":"2018-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994709/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36217764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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