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Impact of Fish Intake Frequency on Cardiovascular Disease-Specific Survival in Hemodialysis Patients. 鱼类摄入频率对血液透析患者心血管疾病生存期的影响
JMA journal Pub Date : 2024-01-15 Epub Date: 2023-12-11 DOI: 10.31662/jmaj.2023-0135
Tadasuke Ando, Tomochika Murakami, Sakura Fujiyama, Shin-Ya Sejiyama, Kan Murakami, Daisuke Miki, Yoshitsugu Fujita, Naomichi Yamaguchi, Ryoichi Shirakami, Satoki Abe, Masahiro Todaka, Shuntaro Suzuki, Hiroyuki Fujinami, Mayuka Shinohara, Shinro Hata, Toru Inoue, Tadamasa Shibuya, Toshitaka Shin, Hiromitsu Mimata
{"title":"Impact of Fish Intake Frequency on Cardiovascular Disease-Specific Survival in Hemodialysis Patients.","authors":"Tadasuke Ando, Tomochika Murakami, Sakura Fujiyama, Shin-Ya Sejiyama, Kan Murakami, Daisuke Miki, Yoshitsugu Fujita, Naomichi Yamaguchi, Ryoichi Shirakami, Satoki Abe, Masahiro Todaka, Shuntaro Suzuki, Hiroyuki Fujinami, Mayuka Shinohara, Shinro Hata, Toru Inoue, Tadamasa Shibuya, Toshitaka Shin, Hiromitsu Mimata","doi":"10.31662/jmaj.2023-0135","DOIUrl":"10.31662/jmaj.2023-0135","url":null,"abstract":"<p><strong>Introduction: </strong>Cardiovascular disease (CVD) is the leading cause of death in hemodialysis patients (HPs). As a food source, fish contains both CVD-preventive and CVD-promoting fatty acids; however, there is no consensus on fish consumption as a preventive measure for CVD in HPs. This single-center longitudinal cohort study aims to assess the impact of fish intake frequency (FIF) per week on CVD in Japanese HPs.</p><p><strong>Methods: </strong>Upon the initiation of the study, 148 HPs were evaluated to determine the FIF, and blood samples were analyzed. These patients were then monitored for 6 years.The relationships between each FIF and blood sampling data, CVD-specific survival (CSS), and new CVD-free survival (nCFS) were statistically calculated using Kaplan-Meier survival curves.</p><p><strong>Results: </strong>During the observation period, 65 deaths were reported, 16 of which were attributed to CVD. Further, 53 patients developed new CVD onset, and no association was found between the FIF and blood sampling data. Based on the Kaplan-Meier survival curves, there was a significant difference in the CSS probability rates at 72 months between patients with an FIF of ≥4 (0.719, 95% confidence interval (CI): 0.530-0.842) and those with an FIF of ≤3 (0.930, 95% CI: 0.851-0.968) (p < 0.01). However, the nCFS probability at 72 months did not significantly differ between patients with an FIF of ≥4 and those with an FIF of ≤3. Multivariate Cox proportional hazards regression showed that an FIF of ≥4 (hazard ratio: 3.64, 95% CI: 1.22-10.9, p = 0.02) was an independent predictor of CSS, but not of nCFS.</p><p><strong>Conclusions: </strong>It was suggested that a higher FIF in HPs might be one of the risks for developing CVD with increased mortality.</p>","PeriodicalId":73550,"journal":{"name":"JMA journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10834181/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139682085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of the COVID-19 Pandemic on Health Check-ups in 2021 and 2022: A Nationwide Follow-up Survey of Healthcare Facilities in Japan Society of Ningen Dock. COVID-19 大流行对 2021 年和 2022 年健康检查的影响:日本宁根码头协会对全国医疗机构的跟踪调查。
JMA journal Pub Date : 2024-01-15 Epub Date: 2023-12-27 DOI: 10.31662/jmaj.2023-0126
Satoko Yamaguchi, Tomofumi Atarashi, Akira Okada, Shigeru Nasu, Toshimasa Yamauchi, Yasuji Arase, Takao Aizawa, Masaomi Nangaku, Takashi Kadowaki
{"title":"Impact of the COVID-19 Pandemic on Health Check-ups in 2021 and 2022: A Nationwide Follow-up Survey of Healthcare Facilities in Japan Society of Ningen Dock.","authors":"Satoko Yamaguchi, Tomofumi Atarashi, Akira Okada, Shigeru Nasu, Toshimasa Yamauchi, Yasuji Arase, Takao Aizawa, Masaomi Nangaku, Takashi Kadowaki","doi":"10.31662/jmaj.2023-0126","DOIUrl":"10.31662/jmaj.2023-0126","url":null,"abstract":"<p><strong>Introduction: </strong>Preventive programs, including screenings for cancer and diabetes, were disrupted globally due to the coronavirus disease 2019 (COVID-19) pandemic in 2020. We previously conducted a nationwide survey to investigate the initial impact of the pandemic on health check-ups; however, the impact in the second and third years of the pandemic has not yet been elucidated. Here, we conducted a follow-up survey targeting healthcare facilities to evaluate the impact of the pandemic until the end of 2022.</p><p><strong>Methods: </strong>A questionnaire survey was conducted between December 15, 2022, and February 10, 2023, targeting member facilities of Japan Society of Ningen Dock. The survey consisted of two parts. Part I comprised a web-based questionnaire, in which the facilities were asked about their commitment to COVID-19-related care, precautions against COVID-19, and whether the pandemic had a negative financial impact on the management of health check-ups. In Part II, the facilities were asked about the number of examinees who underwent health check-ups between 2019 and 2022, the proportion of those who needed and adhered to follow-up visits, and the number of cancer cases found between 2019 and 2021.</p><p><strong>Results: </strong>Of the 1,343 eligible facilities, 885 participated (response rate: 65.9%). The observation that the number of people undergoing mandatory check-ups increased while those undergoing nonmandatory check-ups (e.g., cancer screenings by local governments) decreased in 2021, compared with that of 2019, persisted into 2022. Approximately 60% of the facilities reported a negative financial impact on the management of health check-ups, even in 2022.</p><p><strong>Conclusions: </strong>In 2022, the pandemic's detrimental effects on health check-ups persisted.</p>","PeriodicalId":73550,"journal":{"name":"JMA journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10834170/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139682087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Current Strategies for Perinatal Mental Health Care in Japan. 日本围产期心理保健的现行策略。
JMA journal Pub Date : 2024-01-15 DOI: 10.31662/jmaj.2023-0093
Shunji Suzuki
{"title":"Current Strategies for Perinatal Mental Health Care in Japan.","authors":"Shunji Suzuki","doi":"10.31662/jmaj.2023-0093","DOIUrl":"10.31662/jmaj.2023-0093","url":null,"abstract":"<p><p>Perinatal mental health care is required to maintain the emotional well-being of pregnant women, as well as their children, partners, and families. The mental and physical support for the pregnant and/or postpartum women with serious mental health problems should be provided with multidisciplinary collaboration in the perinatal area. The adverse outcomes related to impaired perinatal mental health are suicide and child abuse, which are the top reasons why mental health care in pregnant and/or postpartum women is important. Mental health care during the perinatal period should be provided proactively with interventions from medical practitioners. In addition, to promote the provision of information on health management for future pregnancies, \"preconception care\" through consultation, supported with medical examinations, is also important.</p>","PeriodicalId":73550,"journal":{"name":"JMA journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10834275/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139682078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluating the Effectiveness of Educational Interventions in Family Planning for Men in Developing Countries: A Systematic Review. 评估发展中国家男性计划生育教育干预措施的效果:系统回顾。
JMA journal Pub Date : 2024-01-15 Epub Date: 2023-11-16 DOI: 10.31662/jmaj.2023-0018
Haruko Tazoe, Riho Tomozawa, Mai Sato, Sumire Anzai, Rikuya Hosokawa
{"title":"Evaluating the Effectiveness of Educational Interventions in Family Planning for Men in Developing Countries: A Systematic Review.","authors":"Haruko Tazoe, Riho Tomozawa, Mai Sato, Sumire Anzai, Rikuya Hosokawa","doi":"10.31662/jmaj.2023-0018","DOIUrl":"10.31662/jmaj.2023-0018","url":null,"abstract":"<p><strong>Introduction: </strong>Unintended pregnancy is associated with national socioeconomic development and gender inequality. In addition to contraception, educational interventions that promote family planning and address gender dynamics are considered important in preventing unintended pregnancy. While the importance of encouraging men's participation in family planning has been advocated, most studies have focused on the application of interventions to women or populations in high-income countries only. Therefore, we conducted a systematic review to evaluate the effects of educational interventions on men in low- and middle-income countries in terms of knowledge, attitudes, practices, and gender dynamics.</p><p><strong>Methods: </strong>Three electronic databases (CINAHL, Ovid MEDLINE, and Web of Science) were searched for studies published from January 1980 to October 2022. Keywords such as \"men/husband,\" \"family planning,\" \"contraception,\" and \"education\" were combined to identify studies. Two independent reviewers conducted screening and data extraction, and the risk of bias was assessed using the Risk of Bias 2 tool. The quality of evidence was evaluated according to the GRADE Handbook.</p><p><strong>Results: </strong>The database search identified 16,086 articles, of which 4 cluster randomized controlled trials (RCTs) and 1 RCT were ultimately included. Each of them was conducted in four different countries: Malawi, Guatemala, Tanzania, and India. Changes in knowledge, attitude, family planning, and gender dynamics were the outcomes used to assess the effectiveness of interventions. The five selected articles exhibited an effect on ≥1 indicator for each outcome. However, the quality of evidence was determined to be low or very low owing to the risk of bias, heterogeneity, and imprecision.</p><p><strong>Conclusions: </strong>Determining the effectiveness of educational interventions in family planning for men in low- and middle-income countries requires additional high-quality intervention studies. As family planning is influenced by various background factors, it is important to develop appropriate interventions for each context and define relevant indicators that can be compared across contexts.</p>","PeriodicalId":73550,"journal":{"name":"JMA journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10834174/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139682081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Literature Review of Studies Using the National Database of the Health Insurance Claims of Japan (NDB): Limitations and Strategies in Using the NDB for Research. 使用日本健康保险索赔国家数据库(NDB)进行研究的文献综述:使用 NDB 进行研究的局限性和策略》。
JMA journal Pub Date : 2024-01-15 Epub Date: 2023-12-27 DOI: 10.31662/jmaj.2023-0078
Maiko Suto, Arisa Iba, Takehiro Sugiyama, Tomoko Kodama, Misa Takegami, Reina Taguchi, Mariko Niino, Ryuji Koizumi, Kimikazu Kashiwagi, Kenjiro Imai, Noriko Ihana-Sugiyama, Yuichi Ichinose, Kenji Takehara, Hiroyasu Iso
{"title":"Literature Review of Studies Using the National Database of the Health Insurance Claims of Japan (NDB): Limitations and Strategies in Using the NDB for Research.","authors":"Maiko Suto, Arisa Iba, Takehiro Sugiyama, Tomoko Kodama, Misa Takegami, Reina Taguchi, Mariko Niino, Ryuji Koizumi, Kimikazu Kashiwagi, Kenjiro Imai, Noriko Ihana-Sugiyama, Yuichi Ichinose, Kenji Takehara, Hiroyasu Iso","doi":"10.31662/jmaj.2023-0078","DOIUrl":"10.31662/jmaj.2023-0078","url":null,"abstract":"<p><p>The use of the National Database of Health Insurance Claims and Specific Health Checkups of Japan (NDB) for research has increased over time. Researchers need to understand the characteristics of the data to generate quality-assured evidence from the NDB. In this review, we mapped and characterized the limitations and related strategies using the NDB for research based on the descriptions of published NDB studies. To find studies that used Japanese healthcare claims data, we searched MEDLINE, EMBASE, and Ichushi-Web up to June 2023. Additionally, we hand-searched the NDB data publication list from the Ministry of Health, Labour and Welfare (2017-2023). We abstracted data based on the NDB data type, research themes, age of the study sample or population, targeted disease, and the limitations and strategies in the NDB studies. Ultimately, 267 studies were included. Overall, the most common research theme was describing and estimating the prescriptions and treatment patterns (125 studies, 46.8%). There was a variation in the frequency of themes according to the type of NDB data. We identified the following categories of limitations: (1) lack of information on confounders/covariates, outcomes, and other clinical content, (2) limitations regarding patients not included in the NDB, (3) misclassification of data, (4) lack of unique identifiers and register of beneficiaries, and (5) others. Although the included studies noted several limitations of using the NDB for research, they also provided some strategies to address them. Organizing the limitations of NDB in research and the related strategies across research fields can help support high-quality NDB studies.</p>","PeriodicalId":73550,"journal":{"name":"JMA journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10834238/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139682089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Estimating Health Expectancy in Japanese Communities Using Mortality Rate and Disability Prevalence. 利用死亡率和残疾率估算日本社区的健康预期。
JMA journal Pub Date : 2024-01-15 Epub Date: 2023-12-27 DOI: 10.31662/jmaj.2023-0058
Rikuya Hosokawa, Toshiyuki Ojima, Tomoya Myojin, Jun Aida, Katsunori Kondo, Naoki Kondo
{"title":"Estimating Health Expectancy in Japanese Communities Using Mortality Rate and Disability Prevalence.","authors":"Rikuya Hosokawa, Toshiyuki Ojima, Tomoya Myojin, Jun Aida, Katsunori Kondo, Naoki Kondo","doi":"10.31662/jmaj.2023-0058","DOIUrl":"10.31662/jmaj.2023-0058","url":null,"abstract":"<p><strong>Introduction: </strong>Although mortality and disability are known to be associated with health expectancy (LE), few studies have assessed the extent to which a reduction in their prevalence can extend a person's LE. Moreover, differences in this relationship based on gender have not been established. Thus, in this study, we constructed a regression model using the rate of mortality and prevalence of disability to predict LE in older adults (≥65 years) and assess the relationships between LE, mortality rate, and disability prevalence based on gender.</p><p><strong>Methods: </strong>Data were collected from Japan's population registry and long-term insurance records (N = 344). Multiple linear regression was used to analyze the relationship between LE, mortality rate, and disability prevalence, stratified by gender.</p><p><strong>Results: </strong>Age-adjusted mortality rate and disability prevalence significantly predicted LE and were significantly correlated with the measured LE index for both genders. For every 1% annual decrease in age-adjusted mortality, LE increased by 1.54 years for men and 2.15 years for women. Similarly, a 1% annual decrease in age-adjusted disability prevalence increased LE by 0.22 years for men and 0.32 years for women. The regression model coefficients indicated that the strength of the association between LE, mortality rate, and disability prevalence differed between genders. Our model accurately predicted LE (men: adjusted R<sup>2</sup> = 0.968, women: adjusted R<sup>2</sup> = 0.994).</p><p><strong>Conclusions: </strong>Health promotion policies that are geared toward increasing health expectancy can be evaluated using mortality rate and disability prevalence as prognostic indicators. The strength of the association between LE, mortality, and disability differed between genders, suggesting the need for gender-specific policy planning to increase LE for both genders.</p>","PeriodicalId":73550,"journal":{"name":"JMA journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10834173/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139682080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Carnitine Deficiency in Intensive Care Unit Patients Undergoing Continuous Renal Replacement Therapy: A Single-center Retrospective Study. 接受持续肾脏替代疗法的重症监护病房患者肉碱缺乏症:一项单中心回顾性研究
JMA journal Pub Date : 2024-01-15 Epub Date: 2023-11-16 DOI: 10.31662/jmaj.2023-0112
Marina Oi, Takaaki Maruhashi, Yasushi Asari
{"title":"Carnitine Deficiency in Intensive Care Unit Patients Undergoing Continuous Renal Replacement Therapy: A Single-center Retrospective Study.","authors":"Marina Oi, Takaaki Maruhashi, Yasushi Asari","doi":"10.31662/jmaj.2023-0112","DOIUrl":"10.31662/jmaj.2023-0112","url":null,"abstract":"<p><strong>Introduction: </strong>Carnitine deficiency is common in patients undergoing intermittent hemodialysis and may also occur during continuous renal replacement therapy (CRRT). We evaluated intensive care unit (ICU) patients undergoing CRRT for carnitine deficiency and its associated risk factors.</p><p><strong>Methods: </strong>This was a single-center, retrospective, observational study performed between June 2019 and March 2020. The primary outcome was the incidence of carnitine deficiency in ICU patients undergoing CRRT.</p><p><strong>Results: </strong>Eighty-eight patients underwent 103 blood carnitine concentration measurements. The median age was 68 years (interquartile range: 55-80), Acute Physiology and Chronic Health Evaluation II score was 28 (24-33), Sequential Organ Failure score was 8.5 (5-11), Nutrition Risk in Critically Ill score was 6 (5-7), and blood carnitine concentration was 66.1 μmol/L (51.8-83.3). In total, 34 of 88 patients (38.6%) were found to have carnitine deficiency; however, there was no significant difference in the proportions of patients with carnitine deficiency characterized by disease. CRRT was performed in 44 (50%) patients, and the median blood total carnitine concentration measured after 24 h of CRRT without changing the settings was 65.5 μmol/L (48.6-83.3). The purification volume of CRRT and blood carnitine concentration were negatively correlated (R = -0.63; P = 0.02).</p><p><strong>Conclusions: </strong>Carnitine deficiency is seen in patients receiving CRRT and may increase in incidence as the purification volume increases, requiring regular monitoring.</p>","PeriodicalId":73550,"journal":{"name":"JMA journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10834172/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139682075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immunoglobulin G4-related Parotitis. 免疫球蛋白 G4 相关性腮腺炎。
JMA journal Pub Date : 2024-01-15 Epub Date: 2023-11-16 DOI: 10.31662/jmaj.2023-0138
Moe Watanabe, Shunichiro Hanai, Ryosuke Ito, Daiki Nakagomi
{"title":"Immunoglobulin G4-related Parotitis.","authors":"Moe Watanabe, Shunichiro Hanai, Ryosuke Ito, Daiki Nakagomi","doi":"10.31662/jmaj.2023-0138","DOIUrl":"10.31662/jmaj.2023-0138","url":null,"abstract":"","PeriodicalId":73550,"journal":{"name":"JMA journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10834152/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139682084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In Vivo Vortex Imaging of Bladder. 膀胱体内涡流成像。
JMA journal Pub Date : 2024-01-15 Epub Date: 2023-11-16 DOI: 10.31662/jmaj.2023-0134
Hideki Mizuno, Seiji Matsumoto, Tokunori Yamamoto
{"title":"In Vivo Vortex Imaging of Bladder.","authors":"Hideki Mizuno, Seiji Matsumoto, Tokunori Yamamoto","doi":"10.31662/jmaj.2023-0134","DOIUrl":"10.31662/jmaj.2023-0134","url":null,"abstract":"","PeriodicalId":73550,"journal":{"name":"JMA journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10834176/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139682318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Case of Two-stage Surgery Using Intracranial Pressure Monitoring for Hemorrhagic Infarction during Direct Oral Anticoagulant Medication. 一例在直接口服抗凝药物期间使用颅内压监测进行出血性脑梗死两阶段手术的病例。
JMA journal Pub Date : 2023-10-16 Epub Date: 2023-09-20 DOI: 10.31662/jmaj.2023-0087
Tatsuya Tanaka, Xuan Liu, Nobuaki Momozaki, Eiichiro Honda, Eiichi Suehiro, Akira Matsuno
{"title":"A Case of Two-stage Surgery Using Intracranial Pressure Monitoring for Hemorrhagic Infarction during Direct Oral Anticoagulant Medication.","authors":"Tatsuya Tanaka, Xuan Liu, Nobuaki Momozaki, Eiichiro Honda, Eiichi Suehiro, Akira Matsuno","doi":"10.31662/jmaj.2023-0087","DOIUrl":"10.31662/jmaj.2023-0087","url":null,"abstract":"<p><p>Direct oral anticoagulants (DOACs) are considered to cause a few hemorrhagic complications, including hemorrhagic infarction; these are administered in the acute phase of cerebral infarction for secondary prevention of cerebral embolism. Hemorrhagic infarction with cerebral herniation requires urgent decompressive craniectomy and can become fatal. Perioperative management is challenging because patients are often on antithrombotic therapy. In this study, we report on a case of a 61-year-old man with left-sided hemiparesis and impaired consciousness; he suffered from a hemorrhagic infarction with cerebral herniation during oral DOAC treatment after endovascular recanalization for the middle cerebral artery occlusion. As the patient was on apixaban for <3 h, performing decompressive craniectomy was considered difficult to stop hemostasis. We then opted to perform a small craniotomy to remove the hematoma, control the intracranial pressure (ICP), and administer fresh frozen plasma. We waited for the effect of apixaban to diminish before performing decompressive craniectomy. Gradually, his level of consciousness was noted to improve. Hemorrhagic cerebral infarction while on DOAC medications can be safely treated with small craniotomy and ICP monitoring followed by decompressive craniectomy. Thus, this case highlights the value of staged surgery under ICP monitoring in the absence of an immediate administration of DOAC antagonists.</p>","PeriodicalId":73550,"journal":{"name":"JMA journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10627977/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71523696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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