JEM reportsPub Date : 2025-06-01Epub Date: 2025-04-16DOI: 10.1016/j.jemrpt.2025.100169
Gabriel Gazetta , Yaoyu Fu , Kaori Tanaka , Brian M. Clemency , Anirban Dutta , Matthew Hackett , Jack Norfleet , Rahul , Suvranu De , Steven Schwaitzberg , Lora Cavuoto
{"title":"A pilot study on physiological indicators of expertise in pre-hospital emergency medical services (EMS) providers during endotracheal intubation","authors":"Gabriel Gazetta , Yaoyu Fu , Kaori Tanaka , Brian M. Clemency , Anirban Dutta , Matthew Hackett , Jack Norfleet , Rahul , Suvranu De , Steven Schwaitzberg , Lora Cavuoto","doi":"10.1016/j.jemrpt.2025.100169","DOIUrl":"10.1016/j.jemrpt.2025.100169","url":null,"abstract":"<div><h3>Background</h3><div>Prehospital intubation is a high risk, low frequency skill. Manikin intubations, the most common means of evaluating providers’ competency, may be insufficient to predict procedural success.</div></div><div><h3>Objective</h3><div>The objective of this pilot study was to explore whether physiological measures, including gaze behavior, pupil response, and cortical activation, differed between groups of pre-hospital emergency medical services (EMS) providers during simulated endotracheal intubation.</div></div><div><h3>Methods</h3><div>Fifteen certified paramedics (expert clinicians) and fifteen Advanced Emergency Medical Technicians (intermediate clinicians) participated in this pilot study. Each participant performed three intubations on a standard airway manikin. During the intubations, pupillometry and gaze data were collected using eye tracking glasses and brain activation using functional near infrared spectroscopy (fNIRS). Groups were compared based on the eye tracking and neuroimaging metrics.</div></div><div><h3>Results</h3><div>Twenty-seven out of 30 participants successfully intubated the manikin across all repetitions, and expert clinicians finished the task on average 11.6s faster than intermediate clinicians. Experts spent less task time in gaze fixation (39.8 % vs. 55.2 %, <em>p</em> = 0.03). Peaks in pupil diameter during the task most often occurred during the sub-task of inserting the tube in the trachea (76% of the time). Neuroimaging results revealed significant group-level differences in the left supramarginal gyrus.</div></div><div><h3>Conclusion</h3><div>This study explored physiological responses during simulated intubation by pre-hospital emergency medicine providers. While some group-level differences were observed in gaze behavior and brain activation, these findings were not sufficient to differentiate expertise. Further research is needed to better understand how physiological responses may reflect task demands in clinical settings.</div></div>","PeriodicalId":73546,"journal":{"name":"JEM reports","volume":"4 2","pages":"Article 100169"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143847997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JEM reportsPub Date : 2025-06-01Epub Date: 2025-04-21DOI: 10.1016/j.jemrpt.2025.100170
Keenan S. Fine , Caroline C. Bay , Gina Krause , Robert E. George , Camille J. LaLiberte , Daniel Y. Cho , C. Corlin Jewell , Hani I. Kuttab
{"title":"Adult facial Fractures: A review and guide for emergency medicine clinicians","authors":"Keenan S. Fine , Caroline C. Bay , Gina Krause , Robert E. George , Camille J. LaLiberte , Daniel Y. Cho , C. Corlin Jewell , Hani I. Kuttab","doi":"10.1016/j.jemrpt.2025.100170","DOIUrl":"10.1016/j.jemrpt.2025.100170","url":null,"abstract":"<div><h3>Background</h3><div>Facial fractures are common injuries in emergency departments across the United States. These can present various challenges for emergency medicine (EM) physicians and other healthcare providers. Managing these injuries can be complex which may be exacerbated by varying availability of specialist support, particularly in rural or community settings.</div></div><div><h3>Objective of review</h3><div>This review aims to provide a comprehensive, evidence-based approach to the management of facial fractures for emergency medicine (EM) clinicians. This review highlights key principles in trauma evaluation, imaging, and indications for surgical consultation to improve decision-making and patient care.</div></div><div><h3>Discussion</h3><div>Facial fracture management begins with systematic trauma evaluation, prioritizing stability, hemorrhage control, and airway patency. Maxillofacial CT without contrast is the preferred imaging modality for most facial fractures with some requiring further imaging. Emergency physicians should recognize high risk features requiring surgical consultation, including displacement, malocclusion, and neurovascular compromise. Orbital and midface fractures may require ophthalmologic consultation if the patient presents with entrapment, globe rupture, or orbital compartment syndrome. In many cases, stable, non-displaced fractures may be managed outpatient with clear return precautions and outpatient surgical follow-up.</div></div><div><h3>Conclusion</h3><div>This review is designed to be accessible and instructive for EM trainees and clinicians. These multidisciplinary guidelines provided can equip EM providers with the knowledge to safely and effectively triage facial fractures.</div></div>","PeriodicalId":73546,"journal":{"name":"JEM reports","volume":"4 2","pages":"Article 100170"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143869205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JEM reportsPub Date : 2025-06-01Epub Date: 2025-02-28DOI: 10.1016/j.jemrpt.2025.100159
Ivana-Re Baldie, Beau Abar, Brenda Hernandez-Romero, Nancy Wood, Adrienne Morgan, David Adler
{"title":"Associations between enroller demographics and participant enrollment into an emergency department-based cancer prevention trial","authors":"Ivana-Re Baldie, Beau Abar, Brenda Hernandez-Romero, Nancy Wood, Adrienne Morgan, David Adler","doi":"10.1016/j.jemrpt.2025.100159","DOIUrl":"10.1016/j.jemrpt.2025.100159","url":null,"abstract":"<div><h3>Background</h3><div>Inadequate diversity among clinical trial participants threatens external validity. Potential explanations for disparities in participation include staff bias, lack of access to studies, and racial discordance between staff and patients.</div></div><div><h3>Objectives</h3><div>We examined associations between patient and enroller demographics and enrollment into a randomized controlled trial (RCT) on cancer screening among Emergency Department (ED) patients. Enrollment through the ED ensures access to trials across a diverse patient population, and the dataset analyzed is of sufficient magnitude and diversity (both in enrollers and patients) to provide novel evaluation.</div></div><div><h3>Methods</h3><div>Research enrollers identified potentially eligible ED patients for enrollment using the electronic health record, approached patients and described the RCT, and attempted to enroll them into the study.</div></div><div><h3>Results</h3><div>A total of 4419 patient-enroller encounters were documented. Enrollment rates were similar across enroller gender (47 % when enroller was a woman; 48 % when enroller was a man), though there was mild variability across enroller race (50 % when enroller was White; 45 % when enroller was Asian; 44 % when enroller was Black). Concordance between patient and enroller race was not tied to enrollment.</div></div><div><h3>Conclusions</h3><div>Conducting research in diverse settings like the ED can mitigate access barriers, as can enroller cultural competency training.</div></div>","PeriodicalId":73546,"journal":{"name":"JEM reports","volume":"4 2","pages":"Article 100159"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143551553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JEM reportsPub Date : 2025-06-01Epub Date: 2025-03-14DOI: 10.1016/j.jemrpt.2025.100161
Alexandra Over, Tyler Nghiem, Pamela Santivanez, Amin Mohamadi, Josh Greenstein, Barry Hahn, William Caputo
{"title":"Ultrasound-guided interscalene block for the reduction of luxatio erecta in a high-risk patient: A case report","authors":"Alexandra Over, Tyler Nghiem, Pamela Santivanez, Amin Mohamadi, Josh Greenstein, Barry Hahn, William Caputo","doi":"10.1016/j.jemrpt.2025.100161","DOIUrl":"10.1016/j.jemrpt.2025.100161","url":null,"abstract":"<div><h3>Background</h3><div>Inferior glenohumeral dislocation (IGD), or luxatio erecta humeri, is a rare shoulder dislocation, accounting for 0.5 % of all cases. It often results from hyperabduction of the arm, causing the humeral head to dislocate inferiorly. IGD is associated with neurovascular complications, particularly in elderly patients with comorbidities. Traditional management involves procedural sedation, which may be risky in high-risk patients. Ultrasound-guided interscalene nerve blocks offer a safer alternative by providing localized pain control without sedation.</div></div><div><h3>Case report</h3><div>We report the case of an 85-year-old male with multiple comorbidities who presented with IGD after a fall. Given the patient's risks, an ultrasound-guided interscalene block was used for reduction. Reduction was achieved using the traction-countertraction method, confirmed by post-reduction radiographs. The patient experienced no immediate complications, and at follow-up, showed no signs of re-dislocation or neurological deficits.<strong>Why should an emergency physician be aware of this?</strong> Ultrasound-guided interscalene nerve blocks provide a safe and effective alternative to procedural sedation for IGD reduction, especially in high-risk patients. This approach minimizes opioid use, improves outcomes, and reduces emergency department resource utilization. Future guidelines should consider incorporating this technique for similar cases, with further studies needed to evaluate long-term outcomes.</div></div>","PeriodicalId":73546,"journal":{"name":"JEM reports","volume":"4 2","pages":"Article 100161"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143643457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JEM reportsPub Date : 2025-06-01Epub Date: 2025-03-20DOI: 10.1016/j.jemrpt.2025.100163
Christine E. Maloney, William B. Prince
{"title":"When itching signals more: A case of chronic pruritus leading to cancer diagnosis","authors":"Christine E. Maloney, William B. Prince","doi":"10.1016/j.jemrpt.2025.100163","DOIUrl":"10.1016/j.jemrpt.2025.100163","url":null,"abstract":"<div><h3>Background</h3><div>Pruritus is a common complaint seen by emergency medicine physicians and carries a broad differential encompassing dermatologic, systemic, neurologic, and psychogenic etiologies.</div></div><div><h3>Case report</h3><div>A 16-year-old girl presented to the emergency department with two months of pruritus and rash. Prior diagnoses for her symptoms included atopic dermatitis, medication-induced tactile hallucinations, and scabies. Physical examination in the emergency department was notable for a firm supraclavicular lymph node and laboratory studies were notable for systemic inflammation. Biopsy revealed a new diagnosis of classical Hodgkin lymphoma.</div></div><div><h3>Why should an emergency physician be aware of this?</h3><div>Recognition of refractory chronic pruritus by frontline providers as a presenting symptom of Hodgkin lymphoma can prevent diagnostic delay.</div></div>","PeriodicalId":73546,"journal":{"name":"JEM reports","volume":"4 2","pages":"Article 100163"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143683255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JEM reportsPub Date : 2025-06-01Epub Date: 2025-04-11DOI: 10.1016/j.jemrpt.2025.100167
Jonathan Mohnkern , Laura Williams , Christopher Fullagar
{"title":"Wide-complex tachycardia with an unusual response to electrical cardioversion in an adolescent with Chiari 1 malformation: A case report","authors":"Jonathan Mohnkern , Laura Williams , Christopher Fullagar","doi":"10.1016/j.jemrpt.2025.100167","DOIUrl":"10.1016/j.jemrpt.2025.100167","url":null,"abstract":"<div><h3>Background</h3><div>Pediatric patients with sustained tachyarrhythmias present unique challenges to prehospital clinicians due to differences in physiology, pathology, compensatory mechanisms, and treatment algorithms. Additionally, pediatric patients require careful thought into the psychosocial impacts that one's demeanor, treatment, and explanations will have on them.</div></div><div><h3>Case report</h3><div>This case illustrates an adolescent male with a history of Chiari 1 malformation who presented to EMS with sustained monomorphic ventricular tachycardia (VT). An unusual rhythm response was experienced during electrical cardioversion, where this intervention resulted in an immediate doubling of his heart rate.</div></div><div><h3>Why should an emergency physician be aware of this?</h3><div>We discuss approaches to pediatric dysrhythmias, differential diagnosis considerations, appropriate management of wide-complex tachycardia, and methods to reduce the psychological burden on patients and families in a first-encounter clinical situation.</div></div>","PeriodicalId":73546,"journal":{"name":"JEM reports","volume":"4 2","pages":"Article 100167"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143837826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JEM reportsPub Date : 2025-06-01Epub Date: 2025-04-02DOI: 10.1016/j.jemrpt.2025.100166
Evan Lawyer , Jessica Krizo , Kailee Pollock , Carline Mangira , Erin L. Simon
{"title":"QTc prolongation and dysrhythmia risk in emergency department patients administered ondansetron","authors":"Evan Lawyer , Jessica Krizo , Kailee Pollock , Carline Mangira , Erin L. Simon","doi":"10.1016/j.jemrpt.2025.100166","DOIUrl":"10.1016/j.jemrpt.2025.100166","url":null,"abstract":"<div><h3>Background</h3><div>Ondansetron, an anti-emetic with the potential to cause QT-prolongation and dysrhythmia, is commonly used in the emergency department. It is unclear how often ondansetron is given to patients with prolonged QT intervals and if these patients are more likely to have dysrhythmias.</div></div><div><h3>Objectives</h3><div>We determined the frequency of the use of ondansetron in patients with a corrected QT (QTc) interval ≥500 ms and the rate of dysrhythmias in this population.</div></div><div><h3>Methods</h3><div>This study was a retrospective review of adult patients who presented to one of 17 EDs within a large integrated healthcare system between May 1, 2021, and April 30, 2023. Patients were included if they had an electrocardiogram (ECG) and received ondansetron. Patients were categorized by QTc length. Categorical variables were described using frequencies and percentages and p-values obtained from Pearson Chi square or Fisher's exact tests where appropriate.</div></div><div><h3>Results</h3><div>A total of 42,530 patients were included. Of these, 56 developed dysrhythmias. Patients administered ondansetron with a measured QTc ≥500 (n = 2302), compared to patients with a measured QTc <500 (n = 40,228), were not at increased risk for developing a dysrhythmia (p = 1.000). A total of 11 patients with a QTc >475 (n = 6572), developed a dysrhythmia and there was an increased incidence of supraventricular tachycardia (p = 0.002) and cardiac arrest (p = 0.002).</div></div><div><h3>Conclusion</h3><div>This study shows that most patients (95 %) who had an ECG and were administered ondansetron have a QTc <500. The incidence of dysrhythmia in patients with a QTc >500 was 0.09 % and in those with a QTc >475 was 0.17 %.</div></div>","PeriodicalId":73546,"journal":{"name":"JEM reports","volume":"4 2","pages":"Article 100166"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143820313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JEM reportsPub Date : 2025-06-01Epub Date: 2025-04-15DOI: 10.1016/j.jemrpt.2025.100168
Eytan Mendelow, Andrew Weinberger, Crista Cerrone
{"title":"Thyrotoxicosis misdiagnosed as anaphylaxis following NSAID use in an adolescent","authors":"Eytan Mendelow, Andrew Weinberger, Crista Cerrone","doi":"10.1016/j.jemrpt.2025.100168","DOIUrl":"10.1016/j.jemrpt.2025.100168","url":null,"abstract":"<div><h3>Background</h3><div>Emergency physicians often encounter patients presenting with symptoms suggestive of common conditions, such as anaphylaxis. However, when clinical findings deviate from the expected course, maintaining a broad differential is critical.</div></div><div><h3>Case report</h3><div>A 17-year-old female presented to the emergency department with flushing, and tachycardia following ibuprofen ingestion.The patient had administered intramuscular epinephrine at home prior to arrival. In the emergency department, she was treated with antihistamines for a presumed anaphylactic reaction. While what was perceived as her facial swelling and hives improved, she remained persistently tachycardic and hypertensive. Further evaluation revealed suppressed TSH and elevated free T4 levels, leading to a diagnosis of thyrotoxicosis. Endocrinology consultation confirmed the findings. The patient was treated with atenolol for symptomatic relief and methimazole to address the underlying thyroid dysfunction.</div><div>Why Should an Emergency Physician Be Aware of This?: This case underscores the importance of re-evaluating initial impressions when a patient's response to treatment is incomplete or atypical. Persistent tachycardia and hypertension after apparent anaphylaxis should prompt consideration of alternative diagnoses, including thyrotoxicosis. Emergency physicians must remain vigilant for less common presentations of thyroid dysfunction, especially when triggered by medications or other stressors, to ensure timely diagnosis and management.</div></div>","PeriodicalId":73546,"journal":{"name":"JEM reports","volume":"4 2","pages":"Article 100168"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143869204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JEM reportsPub Date : 2025-06-01Epub Date: 2025-02-20DOI: 10.1016/j.jemrpt.2025.100154
Yassine Batou , Amine El Farhaoui , Kamal Benalia , Hamza Margoum , Adnane Lachkar , Najib abdeljaouad , Hicham Yacoubi
{"title":"Isolated obturator hip dislocation: A case report and literature review","authors":"Yassine Batou , Amine El Farhaoui , Kamal Benalia , Hamza Margoum , Adnane Lachkar , Najib abdeljaouad , Hicham Yacoubi","doi":"10.1016/j.jemrpt.2025.100154","DOIUrl":"10.1016/j.jemrpt.2025.100154","url":null,"abstract":"<div><h3>Background</h3><div>Obturator dislocation of the hip is an uncommon condition, rarely isolated because it is often associated with a fracture of the acetabulum or the femoral head. It is easy to diagnose because of the abnormal limb positioning it causes, and radiography confirms the diagnosis. The increased risk of complications, particularly avascular necrosis of the femoral head, makes it an emergency for reduction, but the time frame for reduction remains open to debate.</div></div><div><h3>Case Report</h3><div>We report the case of an isolated post-traumatic anteroinferior (obturator) dislocation of the hip in a young man and its clinical, radiological and follow up aspects.</div></div><div><h3>Why should an emergency physician be aware of this</h3><div>Understanding the clinical, radiological, and therapeutic aspects of an obturator hip dislocation is crucial for an emergency physician, as this condition, although rare, can be serious. It typically results from a violent trauma that may conceal life-threatening injuries and can lead to long-term disabling; complications.</div></div>","PeriodicalId":73546,"journal":{"name":"JEM reports","volume":"4 2","pages":"Article 100154"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143480349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Severe pentobarbital poisoning treated after two sessions of intermittent hemodialysis: A case report","authors":"Sohma Miyamoto , Shutaro Isokawa , Norio Otani , Masatoshi Miyamoto , Yoshito Kamijo","doi":"10.1016/j.jemrpt.2025.100174","DOIUrl":"10.1016/j.jemrpt.2025.100174","url":null,"abstract":"<div><h3>Background</h3><div>Pentobarbital is a short-acting barbiturate that can cause life-threatening central nervous system, respiratory, and cardiovascular depression if massively overdosed.</div></div><div><h3>Case report</h3><div>This case report describes a 38-year-old female who entered a deep coma after ingesting 2.45 g of pentobarbital. She had severe respiratory depression and hypotension refractory to fluid administration. The patient was intubated, placed under mechanical ventilation, and given continuous intravenous administration of norepinephrine. She then underwent 2 sessions of intermittent hemodialysis (IHD) lasting 4 h each, after which her clinical condition rapidly improved. The serum pentobarbital concentration determined using liquid chromatography-tandem mass spectrometry (LD/MS/MS) decreased rapidly from 60.61 to 23.75 μg/ml after the first session and from 26.16 to 9.34 μg/ml after the second session. The half-lives of pentobarbital were estimated to be 3.8 and 4.1 h during the first and second sessions, respectively, 157.5 h between the two sessions, and 20.4 h after the second session. The case highlights the potential benefit of IHD in managing pentobarbital toxicity, where enhanced drug clearance may shorten intubation and intensive care unit stay.</div></div><div><h3>Why should an emergency physician should be aware of this?</h3><div>In severe pentobarbital poisoning, hemodialysis may be effective to enhance drug clearance.</div></div>","PeriodicalId":73546,"journal":{"name":"JEM reports","volume":"4 2","pages":"Article 100174"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143941192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}