JCSM rapid communications最新文献

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Muscle mass change using linear measurement analysis after nephrectomy for pT3 and pT4 renal cell carcinoma is associated with mortality pT3和pT4肾细胞癌切除术后肌肉质量变化与死亡率相关
JCSM rapid communications Pub Date : 2022-06-15 DOI: 10.1002/rco2.66
A. Medline, Eric Midenberg, Dattatraya Patil, Sean T. Evans, N. Vettikattu, F. Kamal, K. Ogan, S. Psutka, M. Bilen, V. Master
{"title":"Muscle mass change using linear measurement analysis after nephrectomy for pT3 and pT4 renal cell carcinoma is associated with mortality","authors":"A. Medline, Eric Midenberg, Dattatraya Patil, Sean T. Evans, N. Vettikattu, F. Kamal, K. Ogan, S. Psutka, M. Bilen, V. Master","doi":"10.1002/rco2.66","DOIUrl":"https://doi.org/10.1002/rco2.66","url":null,"abstract":"Preoperative skeletal muscle deficiency is an established risk factor for poor survival outcomes in patients with renal cell carcinoma (RCC). However, given the dynamic nature of skeletal muscle associated with malignancy, there is a need to evaluate the prognostic benefit of muscle area change from the preoperative to postoperative period. We hypothesize that an improvement in muscle area following nephrectomy, measured by linear segmentation of L3 psoas and paraspinal musculature, is associated with improvement in overall survival (OS) and cancer specific survival (CSS) for patients with pT3 and pT4 RCC.","PeriodicalId":73544,"journal":{"name":"JCSM rapid communications","volume":"5 1","pages":"205 - 211"},"PeriodicalIF":0.0,"publicationDate":"2022-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48762448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Human primary skeletal muscle‐derived myoblasts and fibroblasts reveal different senescent phenotypes 人类原发性骨骼肌来源的成肌细胞和成纤维细胞显示出不同的衰老表型
JCSM rapid communications Pub Date : 2022-06-14 DOI: 10.1002/rco2.67
Thomas G. Francis, O. Jaka, G. Ellison‐Hughes, N. Lazarus, S. Harridge
{"title":"Human primary skeletal muscle‐derived myoblasts and fibroblasts reveal different senescent phenotypes","authors":"Thomas G. Francis, O. Jaka, G. Ellison‐Hughes, N. Lazarus, S. Harridge","doi":"10.1002/rco2.67","DOIUrl":"https://doi.org/10.1002/rco2.67","url":null,"abstract":"The age‐related loss of muscle mass and quality, sarcopenia, has many contributing factors, one of which may be cellular senescence, but this is not well defined in human skeletal muscle.","PeriodicalId":73544,"journal":{"name":"JCSM rapid communications","volume":"5 1","pages":"226 - 238"},"PeriodicalIF":0.0,"publicationDate":"2022-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44143484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Computed tomography measured tissue density of pectoral muscle and liver predicts outcomes in heart transplant recipients 计算机断层扫描测量胸肌和肝脏的组织密度预测心脏移植受者的预后
JCSM rapid communications Pub Date : 2022-05-26 DOI: 10.1002/rco2.62
A. Kuchnia, J. Lortie, Katie J Osterbauer, T. Hess, N. Stabo, Nanae Tsuchiya, N. Wheeler, N. Binkley, C. François, M. Schiebler, J. Hermsen, R. Dhingra
{"title":"Computed tomography measured tissue density of pectoral muscle and liver predicts outcomes in heart transplant recipients","authors":"A. Kuchnia, J. Lortie, Katie J Osterbauer, T. Hess, N. Stabo, Nanae Tsuchiya, N. Wheeler, N. Binkley, C. François, M. Schiebler, J. Hermsen, R. Dhingra","doi":"10.1002/rco2.62","DOIUrl":"https://doi.org/10.1002/rco2.62","url":null,"abstract":"Computed tomography (CT)‐derived measures of tissue quality can add to frailty assessment and improve selection of candidates for heart transplant. We investigated the prognostic value of CT measures of tissue density for predicting hospital length of stay (LOS) and mortality post‐transplant.","PeriodicalId":73544,"journal":{"name":"JCSM rapid communications","volume":"5 1","pages":"171 - 181"},"PeriodicalIF":0.0,"publicationDate":"2022-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42461952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Psoas muscle measurement as a marker of sarcopenia predicts risk of Grade 4 or 5 baseline chronic kidney disease and its progression 作为少肌症标志的Psoas肌肉测量可预测4或5级基线慢性肾脏疾病及其进展的风险
JCSM rapid communications Pub Date : 2022-05-23 DOI: 10.1002/rco2.63
Davine Yang, Sameena Iqbal, K. Rafatzand, C. Scheede-Bergdahl
{"title":"Psoas muscle measurement as a marker of sarcopenia predicts risk of Grade 4 or 5 baseline chronic kidney disease and its progression","authors":"Davine Yang, Sameena Iqbal, K. Rafatzand, C. Scheede-Bergdahl","doi":"10.1002/rco2.63","DOIUrl":"https://doi.org/10.1002/rco2.63","url":null,"abstract":"Psoas muscle area (PMA) has recently been found to be an appropriate surrogate for whole‐body skeletal muscle mass and a measure of sarcopenia. Sarcopenia, which includes a decreased muscle mass and correlated with physical disability, morbidity, and mortality, is prevalent in and has deleterious consequences for patients with chronic kidney disease (CKD). The current study investigates the association of PMA, as a marker of sarcopenia, with baseline kidney function and CKD progression.","PeriodicalId":73544,"journal":{"name":"JCSM rapid communications","volume":"5 1","pages":"182 - 193"},"PeriodicalIF":0.0,"publicationDate":"2022-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49600761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The impact of cachexia on dietary intakes, symptoms, and quality of life in advanced cancer 恶病质对晚期癌症患者膳食摄入量、症状和生活质量的影响
JCSM rapid communications Pub Date : 2022-05-09 DOI: 10.1002/rco2.61
K. Amano, V. Baracos, T. Morita, T. Miura, N. Mori, Ryohei Tatara, Takaomi Kessoku, A. Tokoro, Keita Tagami, Hiroyuki Otani, M. Mori, T. Taniyama, N. Nakajima, Erika Nakanishi, J. Kako, Daisuke Kiuchi, H. Ishiki, H. Matsuoka, E. Satomi, M. Miyashita
{"title":"The impact of cachexia on dietary intakes, symptoms, and quality of life in advanced cancer","authors":"K. Amano, V. Baracos, T. Morita, T. Miura, N. Mori, Ryohei Tatara, Takaomi Kessoku, A. Tokoro, Keita Tagami, Hiroyuki Otani, M. Mori, T. Taniyama, N. Nakajima, Erika Nakanishi, J. Kako, Daisuke Kiuchi, H. Ishiki, H. Matsuoka, E. Satomi, M. Miyashita","doi":"10.1002/rco2.61","DOIUrl":"https://doi.org/10.1002/rco2.61","url":null,"abstract":"The relationships between cachexia stages and the Functional Assessment of Anorexia/Cachexia Therapy Anorexia Cachexia Subscale (FAACT ACS) 12‐item, 5‐item anorexia symptoms, and 4‐item anorexia concerns have not been investigated in Asian patients with advanced cancer.","PeriodicalId":73544,"journal":{"name":"JCSM rapid communications","volume":"5 1","pages":"162 - 170"},"PeriodicalIF":0.0,"publicationDate":"2022-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48780092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Resistance exercise training increases skeletal muscle mitochondrial respiration in chronic obstructive pulmonary disease 阻力运动训练增加慢性阻塞性肺疾病骨骼肌线粒体呼吸
JCSM rapid communications Pub Date : 2022-03-14 DOI: 10.1002/rco2.58
L. Oberholzer, Knut Sindre Mølmen, D. Hammarström, G. S. Falch, Anne‐Kristine Meinild Lundby, B. Rønnestad, S. Ellefsen, Carsten Lundby
{"title":"Resistance exercise training increases skeletal muscle mitochondrial respiration in chronic obstructive pulmonary disease","authors":"L. Oberholzer, Knut Sindre Mølmen, D. Hammarström, G. S. Falch, Anne‐Kristine Meinild Lundby, B. Rønnestad, S. Ellefsen, Carsten Lundby","doi":"10.1002/rco2.58","DOIUrl":"https://doi.org/10.1002/rco2.58","url":null,"abstract":"Chronic obstructive pulmonary disease (COPD) is associated with skeletal muscle mitochondrial dysfunction. Resistance exercise training (RT) is a training modality with a relatively small pulmonary demand that has been suggested to increase skeletal muscle oxidative enzyme activity in COPD. Whether a shift into a more oxidative profile following RT also translates into increased mitochondrial respiratory capacity in COPD is yet to be established.","PeriodicalId":73544,"journal":{"name":"JCSM rapid communications","volume":"5 1","pages":"194 - 204"},"PeriodicalIF":0.0,"publicationDate":"2022-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44331897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Microbiota–muscle/immune interactions in rhesus macaque under simulated microgravity revealed by integrated multi‐omics analysis 综合多组学分析揭示模拟微重力条件下恒河猴的微生物群-肌肉/免疫相互作用
JCSM rapid communications Pub Date : 2022-03-11 DOI: 10.1002/rco2.60
Peng Zhang, Libin Shao, Jie Zhang, Lu Wang, Xiangsheng Pang, Wuchen Tao, Guangyi Fan, Ling Peng, Guanghan Kan, Wenjiong Li, Xinming Liang, Xin Liu, Xiaoping Chen
{"title":"Microbiota–muscle/immune interactions in rhesus macaque under simulated microgravity revealed by integrated multi‐omics analysis","authors":"Peng Zhang, Libin Shao, Jie Zhang, Lu Wang, Xiangsheng Pang, Wuchen Tao, Guangyi Fan, Ling Peng, Guanghan Kan, Wenjiong Li, Xinming Liang, Xin Liu, Xiaoping Chen","doi":"10.1002/rco2.60","DOIUrl":"https://doi.org/10.1002/rco2.60","url":null,"abstract":"Long‐term exposure to microgravity during spaceflight has adverse effects on human health including muscle atrophy, impaired immune function, and alterations in gut microbiome profile. Gut microorganisms influence a wide range of host biological processes, but their interactions with skeletal muscle and the immune system under microgravity have yet to be elucidated.","PeriodicalId":73544,"journal":{"name":"JCSM rapid communications","volume":"5 1","pages":"212 - 225"},"PeriodicalIF":0.0,"publicationDate":"2022-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46595937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Overexpression of thioredoxin‐2 attenuates age‐related muscle loss by suppressing mitochondrial oxidative stress and apoptosis 硫氧还蛋白-2的过表达通过抑制线粒体氧化应激和细胞凋亡来减轻年龄相关的肌肉损失
JCSM rapid communications Pub Date : 2022-01-14 DOI: 10.1002/rco2.57
Huibin Tang, Michael Kim, Myung Lee, Kellie Baumann, F. Olguin, Hao He, Yoyo Wang, B. Jiang, Shuhuan Fang, Jinguo Zhu, Kun Wang, Hui Xia, Yang Gao, Harrison B. Konsker, Emmanuel Fatodu, Marco Quarta, Justin Blonigan, T. Rando, J. Shrager
{"title":"Overexpression of thioredoxin‐2 attenuates age‐related muscle loss by suppressing mitochondrial oxidative stress and apoptosis","authors":"Huibin Tang, Michael Kim, Myung Lee, Kellie Baumann, F. Olguin, Hao He, Yoyo Wang, B. Jiang, Shuhuan Fang, Jinguo Zhu, Kun Wang, Hui Xia, Yang Gao, Harrison B. Konsker, Emmanuel Fatodu, Marco Quarta, Justin Blonigan, T. Rando, J. Shrager","doi":"10.1002/rco2.57","DOIUrl":"https://doi.org/10.1002/rco2.57","url":null,"abstract":"Skeletal muscle mass is regulated by intracellular anabolic and catabolic activities. Increased catabolic activity can shift the balance towards net protein breakdown and muscle atrophy. Mitochondrial oxidative stress activates catabolism and is linked to muscle loss. Reducing mitochondrial oxidative stress is thus a plausible approach to prevent muscle atrophy. We tested this concept in age‐dependent muscle atrophy by genetically overexpressing the mitochondrial antioxidant thioredoxin‐2 (TXN2).","PeriodicalId":73544,"journal":{"name":"JCSM rapid communications","volume":"5 1","pages":"130 - 145"},"PeriodicalIF":0.0,"publicationDate":"2022-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43062471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Effects of low‐dose metformin on pre‐frailty among middle‐aged and elderly pre‐diabetic people 低剂量二甲双胍对中老年糖尿病前期人群虚弱前期的影响
JCSM rapid communications Pub Date : 2022-01-04 DOI: 10.1002/rco2.55
Chun‐Feng Huang, M. Shiao, Tso-Yen Mao
{"title":"Effects of low‐dose metformin on pre‐frailty among middle‐aged and elderly pre‐diabetic people","authors":"Chun‐Feng Huang, M. Shiao, Tso-Yen Mao","doi":"10.1002/rco2.55","DOIUrl":"https://doi.org/10.1002/rco2.55","url":null,"abstract":"Pre‐frailty has been identified as a clinically silent mechanism pre‐disposing people to frailty. The goal of this study is to investigate the impact of low‐dose metformin on pre‐diabetic pre‐frail patients (>50 years) on skeletal muscle mass, speed of gait, handgrip power, and health‐related quality of life (HR‐QoL).","PeriodicalId":73544,"journal":{"name":"JCSM rapid communications","volume":"5 1","pages":"33 - 39"},"PeriodicalIF":0.0,"publicationDate":"2022-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46375631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Lenalidomide in cancer cachexia: a randomized trial of an anticancer drug applied for anti‐cachexia 来那度胺治疗癌症恶病质:一项抗恶病质抗癌药物的随机试验
JCSM rapid communications Pub Date : 2022-01-01 DOI: 10.1002/rco2.54
D. Blum, C. Hertler, R. Oberholzer, S. Wolf-Linder, M. Joerger, C. Driessen, F. Strasser
{"title":"Lenalidomide in cancer cachexia: a randomized trial of an anticancer drug applied for anti‐cachexia","authors":"D. Blum, C. Hertler, R. Oberholzer, S. Wolf-Linder, M. Joerger, C. Driessen, F. Strasser","doi":"10.1002/rco2.54","DOIUrl":"https://doi.org/10.1002/rco2.54","url":null,"abstract":"Cancer cachexia (CC) impacts quality of life, physical function, anticancer treatment response, and survival. Inflammation is a prominent pathomechanism of CC. This small‐scale study sets out to investigate the immunomodulatory drug lenalidomide in inflammatory CC in a randomized, double‐blind, placebo‐controlled trial.","PeriodicalId":73544,"journal":{"name":"JCSM rapid communications","volume":"5 1","pages":"68 - 76"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45699965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
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