JCSM clinical reports最新文献

{"title":"Is a decrease of grip strength associated with community mobility restriction in dynapenic older women?","authors":"Margaux Blamoutier,&nbsp;Patrick Boissy,&nbsp;Simon Brière,&nbsp;Geneviève Faucher,&nbsp;Martine Lauzé,&nbsp;Christian Duval","doi":"10.17987/jcsm-cr.v3i1.42","DOIUrl":"10.17987/jcsm-cr.v3i1.42","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>Absolute grip strength (aGS) measures are not only used to detect dynapenia, but can also provide a robust indicator of functional impairments such as mobility limitations. Mobility limitations can impact community mobility. The main objective of this study was to investigate whether dynapenia status measured with aGS can be used as a predictor of the level of community mobility measured by Global Positioning System (GPS) and the Life-Space Assessment questionnaire (LSA) in healthy older adults. It has been shown that body weight related grip strength (GS/BW) is also a clinical predictor of functional limitation. The secondary objective of the study was to assess the relationship between the community mobility and the GS/BW.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method and results</h3>\u0000 \u0000 <p>The population studied (n=62) was composed of a dynapenic group of women (aged 66.4 ± 4.8) according to an aGS threshold of ≤ 19.9kg and an age-matched group of women (aged 66.1 ± 5.2) with no detectable dynapenia. Clinical and laboratory evaluations were conducted to measure functional capacity tests, body composition and respiratory capacity. Body weigth related to grip strength (GS/BW) was computed. During 12 days, each participant wore a GPS receiver unit with a data logging =−.67) compared system during waking hours. <i>Transit distance in vehicle per day</i>, <i>Transit distance on foot per day</i> and <i>Ellipse area</i> were extracted from the time series of GPS data (longitude, latitude) collected at 1 Hz. The <i>Life space</i> was assessed using a questionnaire. A Wilcoxon test was used to compare the 2 groups for the community mobility measures. Then, data of the 2 groups were pooled to assess the relationship between GS/BW and community mobility measures. A Spearman correlation was used. The dynapenic group had indeed lower aGS (z=−5.3, p≤.05, r=−.67) and GS/BW (z=−5.3, p≤.05, r=−.67)compared to the non-dynapenic group. Furthermore, we found a lower performance to the step test (z=−2.5, p=.011, r=−.32) and lower walking speed (z=−2.1, p=033, r=−.27) for the dynapenic group. However, no significant differences (Wilcoxon signed-ranks test) were found for community mobility measures with the GPS and the LSA between the two groups. There were significant positive relationships between the GS/BW and <i>one leg stand</i> test (<i>r</i>=.353, <i>p</i>=0.005), <i>step test</i> (<i>r</i>=.409, <i>p</i>=0.001) and <i>walking speed</i> (<i>r</i>=.428, <i>p</i>=0.001). No significant relationship (Spearman correlation test) was found for the GS/BW and community mobility measures with the GPS and the LSA.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 ","PeriodicalId":73543,"journal":{"name":"JCSM clinical reports","volume":"3 1","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.17987/jcsm-cr.v3i1.42","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45289546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"SARC-F questionnaire identifies physical limitations and predicts post discharge outcomes in elderly patients with cardiovascular disease","authors":"Shinya Tanaka,&nbsp;Kentaro Kamiya,&nbsp;Nobuaki Hamazaki,&nbsp;Ryota Matsuzawa,&nbsp;Kohei Nozaki,&nbsp;Yuta Ichinosawa,&nbsp;Manae Harada,&nbsp;Takeshi Nakamura,&nbsp;Emi Maekawa,&nbsp;Chiharu Noda,&nbsp;Minako Yamaoka-Tojo,&nbsp;Atsuhiko Matsunaga,&nbsp;Takashi Masuda,&nbsp;Junya Ako","doi":"10.17987/jcsm-cr.v3i1.56","DOIUrl":"10.17987/jcsm-cr.v3i1.56","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>A simple and inexpensive sarcopenia screening tool would be beneficial in clinical practice. This study was performed to determine whether SARC-F questionnaire can be used to identify physical limitations and poor prognosis in elderly cardiovascular disease (CVD) patients.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods and results</h3>\u0000 \u0000 <p>The study population consisted of 257 Japanese patients ≥65 years old admitted to our hospital for CVD. Prior to discharge from hospital, SARC-F, handgrip strength, usual gait speed, short physical performance battery score, and 6-minute walking distance were measured in all patients. The patients were divided into two groups according to SARC-F score: SARC-F &lt;4 and SARC-F ≥4. The study endpoint was the first occurrence of all-cause emergency readmission or all-cause mortality. The prevalence rate of SARC-F ≥4 was 26.8%, and increased with age and number of comorbidities. Even after adjusting for covariates, physical function was significantly poorer and the risks of physical function measurements below the critical cut-off values were higher in the SARC-F ≥4 group compared to the SARC-F &lt;4 group. Sixty (23.3%) patients were readmitted and 17 (6.6%) died over a median follow-up period of 11 months (interquartile range: 6–13 months). SARC-F score was a significant predictor of adverse events after discharge. Patients with SARC-F ≥4 showed higher event risk than those with SARC-F &lt;4 (adjusted hazard ratio: 1.78; 95% confidence interval: 1.03–3.07; P = 0.040).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>SARC-F questionnaire is useful to identify patients at high risk of physical limitations and to predict post-discharge outcomes in elderly CVD patients.</p>\u0000 </section>\u0000 </div>","PeriodicalId":73543,"journal":{"name":"JCSM clinical reports","volume":"3 1","pages":"1-11"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.17987/jcsm-cr.v3i1.56","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46759575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Side-effects related to adjuvant CAPOX treatment for colorectal cancer are associated with intermuscular fat area, not with total skeletal muscle or fat, a retrospective observational study","authors":"Rogier L. C. Plas,&nbsp;Klaske van Norren,&nbsp;Harm van Baar,&nbsp;Carla van Aller,&nbsp;Maarten de Bakker,&nbsp;Nadia Botros,&nbsp;Renger F. Witkamp,&nbsp;Annebeth Haringhuizen,&nbsp;Ellen Kampman,&nbsp;Renate Winkels","doi":"10.17987/jcsm-cr.v3i1.46","DOIUrl":"10.17987/jcsm-cr.v3i1.46","url":null,"abstract":"Chemotherapeutic treatment is regularly accompanied by side‐effects. Hydrophilic chemotherapeutics such as capecitabine and oxaliplatin (CAPOX), often used in colorectal cancer treatment, predominantly accumulate in non‐adipose tissues. Therefore the aim of this paper was to investigate whether body composition and fat infiltration in the muscle (muscle attenuation and intermuscular‐adipose‐tissue [IMAT] content) are associated with chemotherapy‐induced toxicities.","PeriodicalId":73543,"journal":{"name":"JCSM clinical reports","volume":"3 1","pages":"1-13"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.17987/jcsm-cr.v3i1.46","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42051300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sarcopenia is a Significant Predictor of Mortality After Abdominal Aortic Aneurysm Repair","authors":"Joshua K. Kays MD,&nbsp;Tiffany W. Liang MD,&nbsp;Teresa A. Zimmers PhD,&nbsp;Daniel P. Milgrom MD,&nbsp;Hamzah Abduljabar BS,&nbsp;Andrew Young BS,&nbsp;Bradford J. Kim MD MHS,&nbsp;Teresa M. Bell PhD,&nbsp;Andres Fajardo MD,&nbsp;Michael P. Murphy MD,&nbsp;Leonidas G. Koniaris MD MBA","doi":"10.17987/jcsm-cr.v3i1.53","DOIUrl":"10.17987/jcsm-cr.v3i1.53","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>Repair of abdominal aortic aneurysms (AAA) decreases the incidence of rupture and death. In cancer patients, sarcopenia has been associated with increased surgical complications and mortality. The impact of sarcopenia on survival after AAA repair has yet to be described.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods and Results</h3>\u0000 \u0000 <p>Patient demographic, laboratory, body composition measurements and survival data were obtained from patients undergoing AAA repair at the Indiana University medical campus over a 5-year period. Univariate and multivariate analyses were performed to identify factors associated with overall survival. Overall, 58.2% presented with sarcopenia. Sarcopenic patients were older (71.8±8.3 versus 66.8±8.1 years; p&lt;0.001), had lower body mass index (BMI) (26.3±5.2 versus 31.5±5.9 kg/m²; p&lt;0.001), higher rates of myosteatosis (84.4% versus 52.%; p&lt;0.001), greater AAA diameter (60.6±14.0 versus 57.8±11.7 mm; p=0.016), higher Charlson Comorbidity Index (CCI) (32.3% versus 25.1% ≥6; p=0.034), and increased rates of rupture (8.2% versus 3.8%; p=0.047). Sarcopenic and nonsarcopenic patients had no difference in 30-day morbidity (8.5% versus 8.5%; p=0.991) or mortality (3.7% versus 0.9%; p=0.07). Univariate analysis demonstrated age, sarcopenia, myosteatosis, CCI, and BMI to be associated with long-term survival. There was no correlation between BMI and sarcopenia. Both sarcopenia and myosteatosis resulted in decreased one-, three-, and five-year survivals compared to their counterparts. On multivariate analysis sarcopenia is independently associated with survival, conferring a 1.6-fold increase in death (p=0.04). The combination of sarcopenia plus myosteatosis doubled the risk of death compared to sarcopenia alone.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>This is the first study to demonstrate that over half of all patients undergoing AAA repair are sarcopenic, a condition associated with increased mortality. Sarcopenia with myosteatosis is associated with double the mortality of sarcopenia alone. CT scan, but not BMI, accurately identifies sarcopenia and myosteatosis. Defining the mechanisms through which sarcopenia contributes to late death after AAA repair is critical to developing novel interventions that may improve survival in this high risk population.</p>\u0000 </section>\u0000 </div>","PeriodicalId":73543,"journal":{"name":"JCSM clinical reports","volume":"3 1","pages":"1-12"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.17987/jcsm-cr.v3i1.53","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48815673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The experience of weight loss and its associated burden in patients with non‐small cell lung cancer: results of an online survey","authors":"Ana Maria Rodriguez, J. Braverman, Dimple Aggarwal, J. Friend, E. Duus","doi":"10.17987/jcsm-cr.v2i2.18","DOIUrl":"https://doi.org/10.17987/jcsm-cr.v2i2.18","url":null,"abstract":"The main objectives of this study were to characterize and compare the burden of non‐small cell lung cancer (NSCLC) patients reporting considerable unintentional weight loss (≥ 5% in the past 6 months or ≥ 2% for a BMI < 20 kg/m2) to those who did not.","PeriodicalId":73543,"journal":{"name":"JCSM clinical reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.17987/jcsm-cr.v2i2.18","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46904336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of sarcopenia in community‐dwelling older people of Mexico City using the EGWSOP (European Working Group on Sarcopenia in Older People) diagnostic criteria","authors":"M. C. Espinel-Bermúdez, E. Ramírez-García, C. García-Peña, A. Salvá, L. Ruiz‐Arregui, Ángel Cárdenas-Bahena, S. Sánchez-García","doi":"10.17987/jcsm-cr.v2i2.9","DOIUrl":"https://doi.org/10.17987/jcsm-cr.v2i2.9","url":null,"abstract":"The aim of this study is to determine the prevalence of sarcopenia in community‐dwelling older people living in Mexico City using the EGWSOP (European Working Group on Sarcopenia in Older People) diagnostic criteria that include muscle mass, muscle strength and physical performance.","PeriodicalId":73543,"journal":{"name":"JCSM clinical reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.17987/jcsm-cr.v2i2.9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44977551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"On the wide field of clinical cachexia, sarcopenia and muscle research","authors":"T. Trippel, N. Ebner, G. Loncar, S. Haehling","doi":"10.17987/jcsm-cr.v2i2.36","DOIUrl":"https://doi.org/10.17987/jcsm-cr.v2i2.36","url":null,"abstract":"The past months have brought an interesting array of international submissions ranging from prognostic implications of body mass index and tissue loss in cancer to chronic kidney disease to this journal. Manuscripts on imaging or biomarkers aspects, among others, draw a heterogeneous picture of clinical reports in the field. Yet, upon completion of JCSM Clinical Reports’ Issue 1, Volume 2 we are delighted to display the rapid progress this editorial project takes on the large topic of cachexia, sarcopenia and muscle research. Coherently, we follow our stringent editorial path and hope to consider and integrate a ‘broad field’ from a clinical point of view.","PeriodicalId":73543,"journal":{"name":"JCSM clinical reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42027154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mitochondrial respiratory chain deficiency in older men and its relationship with muscle mass and performance","authors":"K. Rygiel, R. Dodds, H. Patel, H. Syddall, L. Westbury, A. Granic, C. Cooper, Joshua Cliff, M. Rocha, D. Turnbull, A. Sayer","doi":"10.17987/jcsm-cr.v2i2.35","DOIUrl":"https://doi.org/10.17987/jcsm-cr.v2i2.35","url":null,"abstract":"Sarcopenia is the loss of muscle mass and physical performance with age, and recognition of its importance in clinical practice is growing. Age‐related decline in muscle mitochondrial function has been described although less is known about the role of mitochondrial dysfunction in sarcopenia. The aim of this study was to investigate whether respiratory chain deficiency is associated with muscle mass and physical performance among a sample of healthy older men participating in the Hertfordshire Sarcopenia Study.","PeriodicalId":73543,"journal":{"name":"JCSM clinical reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48717880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mediterranean Diet attenuates risk of frailty and sarcopenia: New insights and future directions","authors":"Rebecca McClure,&nbsp;Anthony Villani","doi":"10.17987/jcsm-cr.v2i2.45","DOIUrl":"10.17987/jcsm-cr.v2i2.45","url":null,"abstract":"<div>\u0000 \u0000 <p>Sarcopenia and physical frailty are associated with progressive disability and predictive of negative health outcomes. Dietary interventions are considered the cornerstone in the management of sarcopenic symptomology and physical frailty. However few studies have investigated preventative strategies. Moreover, most studies have focused on the efficacy of individual nutrients or supplements rather than dietary patterns. The Mediterranean Diet (MedDiet) is a dietary pattern that provides evidence for an association between diet quality, healthy ageing and disease prevention. The purpose of this paper was to examine, synthesise and develop a narrative review of the current literature, investigating the potential benefits associated with adherence to a MedDiet and attenuation of physical frailty and sarcopenic symptomology in older adults. We also explored the underlying mechanisms underpinning the potential benefits of the MedDiet on ameliorating physical frailty and sarcopenic symptomology. Synthesis of the reviewed literature is suggestive of a decreased risk of physical frailty and sarcopenic symptomology with greater adherence to a MedDiet. We identified the anti-inflammatory and high antioxidant components of the MedDiet as two potential biological mechanisms involved. Due to a lack of evidence from RCTs to support the proposed physiological mechanisms, we suggest investigating these observations in older adults with type 2 diabetes (T2DM) whom are vulnerable to physical frailty and disability. A number of biological mechanisms describing the pathway to disability in older adults with T2DM have been postulated with many of these mechanisms potentially mitigated with dietary interventions involving the MedDiet. Exploring these mechanisms with the use of well-designed, longer-term dietary intervention studies in older adults with an increased vulnerability to physical frailty and sarcopenia is warranted.</p>\u0000 </div>","PeriodicalId":73543,"journal":{"name":"JCSM clinical reports","volume":"2 2","pages":"1-17"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.17987/jcsm-cr.v2i2.45","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46713249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sarcopenia: Prevalence and Prognostic Implications in Elderly Patients with Cardiovascular Disease","authors":"Kentaro Kamiya,&nbsp;Nobuaki Hamazaki,&nbsp;Ryota Matsuzawa,&nbsp;Kohei Nozaki,&nbsp;Shinya Tanaka,&nbsp;Yuta Ichinosawa,&nbsp;Emi Maekawa,&nbsp;Chiharu Noda,&nbsp;Minako Yamaoka-Tojo,&nbsp;Atsuhiko Matsunaga,&nbsp;Takashi Masuda,&nbsp;Junya Ako","doi":"10.17987/jcsm-cr.v2i2.41","DOIUrl":"10.17987/jcsm-cr.v2i2.41","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>Sarcopenia has recently been given an ICD-10 code. However, there have been no systematic investigations regarding the prevalence or prognostic value of sarcopenia in cardiovascular disease (CVD) according to the international consensus definition. The present study was performed to investigate the prevalence and prognostic value of sarcopenia in elderly patients with CVD.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods and results</h3>\u0000 \u0000 <p>The study population consisted of 1603 admitted patients aged ≥ 65 years (74.4 ± 6.2 years, 1049 men) with CVD. Sarcopenia was defined according to the recommended diagnostic algorithm of the Asia Working Group for Sarcopenia. The endpoint for the study was all-cause mortality. The overall sarcopenia prevalence rate was 29.7% (19.6% in men and 48.7% in women). The prevalence rates of sarcopenia across major diagnostic categories were as follows: acute coronary syndrome, 17.8%; post-cardiac surgery, 31.8%; and heart failure, 35.2%. During the 2.3 ± 2.1-year follow-up period, 175 deaths occurred. Patients with sarcopenia showed higher risk of all-cause mortality compared with non-sarcopenic patients (adjusted hazard ratio: 1.44; 95% confidence interval: 1.01 – 2.05; <i>P</i> = 0.044).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Sarcopenia is highly prevalent among elderly patients with CVD and is associated with increased mortality risk.</p>\u0000 </section>\u0000 </div>","PeriodicalId":73543,"journal":{"name":"JCSM clinical reports","volume":"2 2","pages":"1-13"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.17987/jcsm-cr.v2i2.41","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41783279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}