JCIS open最新文献_第6页

Evaluating pesticide ecotoxicity using a stimuli-response model in liposomes 用脂质体刺激反应模型评价农药生态毒性

JCIS open Pub Date : 2023-07-01 DOI: 10.1016/j.jciso.2023.100082

Seiichi Morita , Chinatsu Sakai , Marika Sakamoto , Makoto Nishimoto

{"title":"Evaluating pesticide ecotoxicity using a stimuli-response model in liposomes","authors":"Seiichi Morita , Chinatsu Sakai , Marika Sakamoto , Makoto Nishimoto","doi":"10.1016/j.jciso.2023.100082","DOIUrl":"10.1016/j.jciso.2023.100082","url":null,"abstract":"<div><p>Pesticides are widely used around the home and in agriculture to control unwanted populations; however, they may also be toxic to non-targeted organisms. Because traditional methods of assessing pesticide toxicity are expensive, lengthy, and ethically questionable, we evaluated pesticide toxicities using stimuli-responses in liposomes. Pesticide ecotoxicity was evaluated using 1,2-dipalmitoyl-<em>sn</em>-glycero-3-phosphocholine (DPPC) and 1,2-dioleoyl-<em>sn</em>-glycero-3-phosphocholine (DOPC) liposomes. Changes in membrane permeability were measured using calcein leakage assays as stimuli-responses in the presence of six pesticides (Chlorpyrifos-methyl, fluometuron, imidacloprid, pirimicarb, pyrethrin, and quizalofop-ethyl), for which the calcein release rate was analyzed using a first-order kinetics equation. The calcein release rate constants of the DPPC liposomes were used to classify the pesticides into lower and higher toxicity groups. In each group, the initial calcein release rate from the DPPC/DOPC liposomes mixed with 33 mol% DOPC correlated well with previously reported pesticide toxicities. The DOPC liposomes underwent lateral phase separation in a different manner between the two toxicity groups. Pesticides with lower toxicities were partitioned in the DPPC-enriched phase, disrupting the gel phase order through their hydrophobicity, whereas pesticides with higher toxicity were partitioned in the DOPC-enriched phase and stabilizing the liquid disordered phase owing to their hydrophobicity and molecular shape. The toxicity of each pesticide was well represented by an equation that combined the calcein release rate constant of the DPPC liposomes and the initial calcein release rate of the 33 mol% DOPC mixed liposomes. The findings indicate that stimuli-response assays using liposomes can be used to complement traditional ecotoxicity assessments.</p></div>","PeriodicalId":73541,"journal":{"name":"JCIS open","volume":"10 ","pages":"Article 100082"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46868063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Biophysical investigation of vape additives with complex lung surfactant model systems and physiological surfactant extracts 复合肺表面活性剂模型体系和生理表面活性剂提取物对电子烟添加剂的生物物理研究

JCIS open Pub Date : 2023-07-01 DOI: 10.1016/j.jciso.2023.100085

Nicolas van Bavel , Patrick Lai , Matthias Amrein , Elmar J. Prenner

{"title":"Biophysical investigation of vape additives with complex lung surfactant model systems and physiological surfactant extracts","authors":"Nicolas van Bavel , Patrick Lai , Matthias Amrein , Elmar J. Prenner","doi":"10.1016/j.jciso.2023.100085","DOIUrl":"10.1016/j.jciso.2023.100085","url":null,"abstract":"<div><h3>Hypothesis</h3><p>Selected vape additives, vitamin E acetate and CBD, are suspected agents in pathology of vape related lung illnesses. The lipophilic nature of these molecules allow them to partition into lung surfactant and disrupt proper function. Such dysfunction can lead to respiratory distress and hypoxemia, two common symptoms of this new class of lung injury.</p></div><div><h3>Experiments</h3><p>Lung surfactant models were formed by depositing lipids at the air-water interface on a Langmuir-Blodgett trough. Surface pressure-area isotherms were conducted for lipid-additive systems to determine changes in lipid packing, film elasticity, and film stability, while Brewster angle microscopy was used to visualize lateral film organization.</p></div><div><h3>Findings</h3><p>Vape additives were found to interfere with proper lipid packing, inducing fluidization throughout the lipid films. Additionally, this hindered the formation of lipid condensed domains. Such structures are necessary for surfactant protein anchoring in order to facilitate the formation of multilayers. In complex model systems, this vital processes was significantly impaired, namely by vitamin e acetate. These data suggest a vape additive induced dysfunction of lipid films which may be involved in the pathology of vape-related lung injury.</p></div>","PeriodicalId":73541,"journal":{"name":"JCIS open","volume":"10 ","pages":"Article 100085"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47220385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis of MnOx from pectin-driven sol-gel route for catalytic oxidation of toluene 果胶驱动溶胶-凝胶法合成甲苯催化氧化MnOx的研究

JCIS open Pub Date : 2023-04-01 DOI: 10.1016/j.jciso.2023.100076

Jinggang Zhao , Peifen Wang , Jing Wang , Xiaoxun Ma , Lei Shi , Guangwen Xu , Abuliti Abudula , Guoqing Guan

{"title":"Synthesis of MnOx from pectin-driven sol-gel route for catalytic oxidation of toluene","authors":"Jinggang Zhao , Peifen Wang , Jing Wang , Xiaoxun Ma , Lei Shi , Guangwen Xu , Abuliti Abudula , Guoqing Guan","doi":"10.1016/j.jciso.2023.100076","DOIUrl":"https://doi.org/10.1016/j.jciso.2023.100076","url":null,"abstract":"<div><p>A novel green pectin-driven sol-gel with an auto-combustion route was successfully applied for the synthesis of manganese oxide catalysts, which exhibited superior catalytic performance for low-temperature combustion of toluene compared to those cases using manganese oxide catalysts synthesized by traditional citric acid and glycine-driven sol-gel routes. The characterization results showed that the MnO<sub><em>x</em></sub>-P catalyst synthesized by the present method exhibited a unique hierarchical mesoporous structure with lower crystallinity and smaller grain size, leading to abundant active species and defect structures. Comparing with the catalysts synthesized by those traditional sol-gel methods, the MnO<sub><em>x</em></sub>-P catalyst had excellent low-temperature reducible performance and better oxygen mobility, which is considered to be resulted from the specific interaction of chelation and calcination processes. In addition, the MnO<sub><em>x</em></sub>-P catalyst exhibited satisfactory long-term stability and water tolerance during catalytic toluene combustion process.</p></div>","PeriodicalId":73541,"journal":{"name":"JCIS open","volume":"9 ","pages":"Article 100076"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49698700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Protein corona formation on epigallocatechin gallate-Au nanoparticles suppressed tumor accumulation 表没食子儿茶素没食子酸-金纳米粒子的蛋白冠形成抑制肿瘤积聚

JCIS open Pub Date : 2023-04-01 DOI: 10.1016/j.jciso.2023.100074

Chihiro Wakayama , Sachiko Inubushi , Tomonari Kunihisa , Sachiko Mizumoto , Motoi Baba , Hirokazu Tanino , Ik Sung Cho , Tooru Ooya

引用次数: 0

Hybrid heterostructured Langmuir-Blodgett films based on graphene and triruthenium clusters as electrode for energy storage devices 基于石墨烯和三钌团簇的混合异质结构Langmuir-Blodgett薄膜作为储能器件的电极

JCIS open Pub Date : 2023-04-01 DOI: 10.1016/j.jciso.2023.100080

Alejandro E. Pérez Mendoza , Ariane Schmidt , Elizangela Cavazzini Cesca , Eduard Westphal , José P.M. Serbena , Elisa S. Orth , Aldo J.G. Zarbin , Herbert Winnischofer

{"title":"Hybrid heterostructured Langmuir-Blodgett films based on graphene and triruthenium clusters as electrode for energy storage devices","authors":"Alejandro E. Pérez Mendoza , Ariane Schmidt , Elizangela Cavazzini Cesca , Eduard Westphal , José P.M. Serbena , Elisa S. Orth , Aldo J.G. Zarbin , Herbert Winnischofer","doi":"10.1016/j.jciso.2023.100080","DOIUrl":"https://doi.org/10.1016/j.jciso.2023.100080","url":null,"abstract":"<div><p>The design of electrodes with highly exposed electroactive sites and improved charge transport that overcomes the current limitations of pseudocapacitors may result in electrodes with high capacity at high rates. These energy storage electrodes are interesting and may have applications as micro-supercapacitors for wearable and implantable devices. Herein, hybrid heterostructured thin film electrodes based on triruthenium clusters and graphene were constructed using the Langmuir-Blodgett (LB) technique. The hybrid thin film performance as supercapacitor electrode was demonstrated in a three-electrode set-up and in asymmetric supercapacitors using graphene as negative electrode and B-PVA-KCl as electrolyte. The hybrid heterostructured LB films exhibited high efficiency as active material and excellent performance at high rates. It led to a better device performance as compared with devices using just triruthenium cluster LB films, achieving a capacitance of 0.710 mF cm<sup>−2</sup> for an 8-monolayer hybrid heterostructured thin film, which is comparable to other graphene metal oxide hybrid electrodes. This performance was attributed to improved charge transport due to the organized heterostructured LB structure and contributions of both faradaic fast redox reaction from ruthenium(II/III) centers and high double-layer capacitance of the graphene sheets.</p></div>","PeriodicalId":73541,"journal":{"name":"JCIS open","volume":"9 ","pages":"Article 100080"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49698683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bead milled drug nanocrystal suspensions fine enough to pass through 0.22 μm sterilization filters 珠磨药物纳米晶体悬浮液，细到足以通过0.22 μm杀菌过滤器

JCIS open Pub Date : 2023-04-01 DOI: 10.1016/j.jciso.2023.100075

Carl-Johan Carling, Anna Pekkari

{"title":"Bead milled drug nanocrystal suspensions fine enough to pass through 0.22 μm sterilization filters","authors":"Carl-Johan Carling, Anna Pekkari","doi":"10.1016/j.jciso.2023.100075","DOIUrl":"10.1016/j.jciso.2023.100075","url":null,"abstract":"<div><p>Nanocrystal suspensions have been introduced to overcome the low bioavailability of poorly water-soluble drug compounds by increasing the dissolution rates. For both injection- and inhalation-based administrations it is important that the suspensions are sterile to eliminate any adverse events from potential microbial infections, but it has proven very challenging to sterilize nanocrystal suspensions without aggregation or degradation. Here we describe bead milling methodology to generate ultrafine nanocrystal suspensions of several poorly water-soluble drug compounds that can be passed through 0.22 μm sterilization filters. The most important factors for successful milling to ultrafine nanocrystal suspensions are the stabilizer excipients combined with fine milling-beads. The sodium dodecyl sulphate (SDS) or docusate sodium/aerosol OT (AOT) combined with Polyvinylpyrrolidone K30 (PVP) stabilizer systems and 1,2-Dipalmitoryl-sn-Glycero-3-Phosphoethanolamine conjugated methoxy Polyethylene Glycol (DPPE) and 1,2-Distearoyl-sn-Glycero-3-Phosphoethanolamine conjugated methoxy Polyethylene Glycol (DSPE) surfactants were among the best stabilizer excipients studied.</p></div>","PeriodicalId":73541,"journal":{"name":"JCIS open","volume":"9 ","pages":"Article 100075"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43932408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Emerging advancements in xerogel polymeric bionanoarchitectures and applications 静电凝胶聚合物生物纳米结构及其应用的新进展

JCIS open Pub Date : 2023-04-01 DOI: 10.1016/j.jciso.2022.100073

Christopher Igwe Idumah

{"title":"Emerging advancements in xerogel polymeric bionanoarchitectures and applications","authors":"Christopher Igwe Idumah","doi":"10.1016/j.jciso.2022.100073","DOIUrl":"10.1016/j.jciso.2022.100073","url":null,"abstract":"<div><p>Xerogels (X-G) are biopolymeric and zero chemical materials, applied in regenerative medicine and tissue engineering because of inherently elevated biocompatibility, nil-immunogenicity, as well as zero-cytotoxicity. X-G are porous, functional and advanced materials composed of dried, cross-linked and ambient polymeric structures possessing very elevated porosity, broad surface area, as we as inexpensive fabrication pathway capable of being garnered from varying organic and inorganic initiators for multifunctional applications. Due to their inherently desirous properties, X-G are appropriate for numerous medical as well as biomedical uses. Relative to their elevated drug delivery capacity, X-G ability of maintaining sustainable drug releasing present them highly suitable for drug conveying applications. Biopolymeric materials exhibit capability of interacting, cross-linking, and/or trapping severally inclined active entities, like antibiotics or naturally occurring antimicrobial substrates, which are critically essential for wound dressing as well as other mending applications. Hence, X-G are capable of being utilized in antibodies trapping, enzymes, as well as cells for biosensor and monitoring gadgets. Therefore, this paper presents recently emerging trends in X-G polymeric bionanoarchitectures encompassing biopolymeric X-G introduction, strategies of construction, as well as their properties. Herein, biological attributes sustaining their suitability for versatile biomedical uses especially biosensing, tissue scaffolding, drug conveying, wound mending and dressing are comprehensively elucidated.</p></div>","PeriodicalId":73541,"journal":{"name":"JCIS open","volume":"9 ","pages":"Article 100073"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48641890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 14

Characteristic length and curvature of the AOT/brine/squalane “sponge” L3 phases AOT/盐水/角鲨烷“海绵”L3相的特征长度和曲率

JCIS open Pub Date : 2023-04-01 DOI: 10.1016/j.jciso.2023.100077

Giuseppe Tartaro, Luigi Gentile, Gerardo Palazzo

{"title":"Characteristic length and curvature of the AOT/brine/squalane “sponge” L3 phases","authors":"Giuseppe Tartaro, Luigi Gentile, Gerardo Palazzo","doi":"10.1016/j.jciso.2023.100077","DOIUrl":"10.1016/j.jciso.2023.100077","url":null,"abstract":"<div><p>The effect of salinity (NaCl concentration) was determined at 25 °C for systems composed of sodium bis(2-ethylhexyl) sulfosuccinate (AOT) and equal volumes of squalane and brine. At all the NaCl concentrations the samples are triphasic with an upper phase made of pure squalane while brine is present in two other phases. At NaCl concentration (in brine) below 1.6 %w/v there is the coexistence of lamellar and sponge (L<sub>3</sub>) phases. Loading with NaCl above 1.6 %w/v one observes the coexistence of L<sub>3</sub> and pure brine. The amount of AOT dissolved in the AOT bilayer has been quantified by thermogravimetric analysis. At salinity above 2 %w/v of NaCl in brine, the AOT sponge phase shrinks expelling brine and the squalane whose presence in the bilayer becomes negligible. The L<sub>3</sub> phases have been further characterized by SAXS and diffusion-NMR. The measured self-diffusion coefficients of water and AOT are essentially coincident with those measured at the same salinity in the absence of squalane. The SAXS curves of sponge phases have been fitted to a single equation accounting for the contributions of the bilayer structure and of the large-scale interactions allowing the determination of the average interpore separation D∗ and the bilayer correlation length ξ. The correlation length has been interpreted as reflecting static randomness of connected bilayer instead of the dynamic thermal undulations. Considering the correlation length as the displacement along the bilayer surface subtending a critical angular change (θ∗) below which the surface appears as flat, permits to define the curvature (H) as |H| <span><math><mrow><mo>=</mo><mfrac><msup><mi>θ</mi><mo>∗</mo></msup><mi>ξ</mi></mfrac></mrow></math></span>. The correlation length scales linearly with the square of the bilayer volume fraction as proposed by a previous theoretical model assuming the sponge phases are thermodynamically constrained to a curvature that equals the spontaneous curvature.</p></div>","PeriodicalId":73541,"journal":{"name":"JCIS open","volume":"9 ","pages":"Article 100077"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44976440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Low doses of pharmaceutical formulations loaded with UFMG-V4N2 immunogen induce the production of IgG anti-cocaine antibodies and provide evidence of cerebral protection in the preclinical model 低剂量加载UFMG-V4N2免疫原的药物制剂可诱导抗可卡因抗体IgG的产生，并在临床前模型中提供脑保护证据

JCIS open Pub Date : 2023-04-01 DOI: 10.1016/j.jciso.2023.100078

Bruna Rodrigues Dias Assis , Paulo Sérgio de Almeida Augusto , Raissa Lima Gonçalves Pereira , Sordaini Maria Caligiorni , Brian Sabato , Larissa Pires do Espírito Santo , Karine Dias dos Reis , Leonardo da Silva Neto , Simone Odília Antunes Fernandes , Valbert Nascimento Cardoso , Maila Castro Lourenço das Neves , Ângelo de Fátima , Frederico Duarte Garcia , Gisele Assis Castro Goulart

{"title":"Low doses of pharmaceutical formulations loaded with UFMG-V4N2 immunogen induce the production of IgG anti-cocaine antibodies and provide evidence of cerebral protection in the preclinical model","authors":"Bruna Rodrigues Dias Assis , Paulo Sérgio de Almeida Augusto , Raissa Lima Gonçalves Pereira , Sordaini Maria Caligiorni , Brian Sabato , Larissa Pires do Espírito Santo , Karine Dias dos Reis , Leonardo da Silva Neto , Simone Odília Antunes Fernandes , Valbert Nascimento Cardoso , Maila Castro Lourenço das Neves , Ângelo de Fátima , Frederico Duarte Garcia , Gisele Assis Castro Goulart","doi":"10.1016/j.jciso.2023.100078","DOIUrl":"10.1016/j.jciso.2023.100078","url":null,"abstract":"<div><p>Anti-cocaine vaccines are a promising therapeutic strategy for treating cocaine use disorders. Here we hypothesize that nanoemulsions (NE) or suspensions (SS) loaded with the calix [4]arene-based immunogen UFMG-V4N2 can induce the production of anti-cocaine antibodies and decrease the passage of radiolabeled cocaine analog [<sup>99m</sup>Tc]Trodat-1 through of the brain barrier. UFMG-V4N2 was characterized (solubility, morphology, DSC, XRD) and loaded into NEs and SSs using excipients approved for human use. Immunogenic efficacy was assessed by quantifying the titers and determining the specificity of anti-cocaine IgG antibodies, and by assessing the inhibition of [<sup>99m</sup>Tc]Trodat-1 trafficking across the mice brain-barrier. UFMG-V4N2 is an amorphous, thermally stable molecule with very low hydrophilicity. The immunogenicity of NE or SS was similar, but aluminum phosphate and the lower dose of UFMG-V4N2 induced higher anti-cocaine IgG antibody titers, minimizing [<sup>99m</sup>Tc]Trodat-1 uptake in the brain. Therefore, the UFMG-V4N2 may represent an alternative for the treatment of cocaine use disorder.</p></div>","PeriodicalId":73541,"journal":{"name":"JCIS open","volume":"9 ","pages":"Article 100078"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47332051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Low viscosity liquid bridges: Stretching of liquid bridges immersed in a higher viscosity liquid 低粘度液桥:浸在高粘度液体中的液桥拉伸

JCIS open Pub Date : 2023-04-01 DOI: 10.1016/j.jciso.2023.100079

Ramon Lopez , Jovina Vaswani , Dylan T. Butler , Joseph McCarthy , Sachin S. Velankar

{"title":"Low viscosity liquid bridges: Stretching of liquid bridges immersed in a higher viscosity liquid","authors":"Ramon Lopez , Jovina Vaswani , Dylan T. Butler , Joseph McCarthy , Sachin S. Velankar","doi":"10.1016/j.jciso.2023.100079","DOIUrl":"10.1016/j.jciso.2023.100079","url":null,"abstract":"<div><p>We examine the dynamics of a liquid bridge between a sphere and a flat plate being separated from each other. Unlike previous research, this paper focuses on the case where the viscosity of the bridge is lower than that of the external fluid within which the particle, the plate, and the liquid bridge are immersed. For the general case of a viscosity mismatch between the bridge fluid and the external fluid, we develop a lubrication theory-based model for the viscous force during separation. The model predicts that a low viscosity bridge reduces the force as compared to both - separation without a liquid bridge, or separation with a bridge of matched viscosity. The magnitude of force reduction is expected to be more severe at small sphere-plate separations and at large bridge volumes. Experiments confirm all these predictions qualitatively, but unexpectedly the magnitude of the reduction is even larger than predicted. Experiments also find that the bridge length at rupture for specified velocity exceeds that for quasistatic rupture by an amount that increases with the squareroot of the velocity. Although we only examine bridges between a plate and a spherical particle, all results are expected to apply for bridges between a pair of particles as well.</p></div>","PeriodicalId":73541,"journal":{"name":"JCIS open","volume":"9 ","pages":"Article 100079"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45965116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0