JACC. Asia最新文献

{"title":"Cancer Therapy-Related Cardiac Dysfunction in Patients Using Immune Checkpoint Inhibitors: A Multicenter Study.","authors":"Chieh-Yu Chang, Chun-Chi Chen, Wen-Kuan Huang, Ming-Jer Hsieh, Ming-Lung Tsai, Cheng-Hung Lee, Tien-Hsing Chen, Shao-Wei Chen, Kuo-Chun Hung, Wen-Cheng Chang, Pao-Hsien Chu, I-Chang Hsieh, Ming-Shien Wen, Yu-Ching Wang, Dong-Yi Chen","doi":"10.1016/j.jacasi.2025.04.009","DOIUrl":"https://doi.org/10.1016/j.jacasi.2025.04.009","url":null,"abstract":"","PeriodicalId":73529,"journal":{"name":"JACC. Asia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144327983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Noncoronary Sinus Pivot Implantation for Transcatheter Aortic Valve Replacement With Self-Expanding Valve for Aortic Regurgitation.","authors":"Lifan Yang, Zilong Weng, Shasha Chen, Yuan Zhang, Daxin Zhou, Wenzhi Pan, Junbo Ge","doi":"10.1016/j.jacasi.2025.04.004","DOIUrl":"https://doi.org/10.1016/j.jacasi.2025.04.004","url":null,"abstract":"<p><strong>Background: </strong>Our initial study suggested that patients undergoing transcatheter aortic valve replacement (TAVR) with a self-expanding valve for pure native aortic regurgitation (PNAR) had a lower rate of major adverse cardiac events (MACE) when the noncoronary sinus pivot implantation (NCPI) was achieved.</p><p><strong>Objectives: </strong>This study enrolled patients with PNAR who underwent TAVR with self-expanding valves between January 2019 and April 2024, compared the NCPI strategy with the conventional approach, and analyzed factors associated with successful NCPI.</p><p><strong>Methods: </strong>We divided 87 patients into an early (conventional) group of patients treated before February 2023 and a late (NCPI strategy) group of patients treated after February 2023. Then the patients were also categorized by successful NCPI and non-NCPI group.</p><p><strong>Results: </strong>The late group had significantly higher device success rates than the early group (92.9% vs 73.3%; P = 0.016) and lower rates of MACE (19.5% vs 51.1%; P = 0.002) and valve-in-valve implantation (4.8% vs 24.4%; P = 0.01). Importantly, NCPI was achieved in 90.5% of patients in the late group compared with only 17.8% in the early group (P < 0.001). The NCPI group had a higher device success rate (93.5% vs 70.7%; P = 0.005) and lower MACE rate (17.4%vs 56.1%; P < 0.001) than the non-NCPI group. NCPI (OR: 6.71; P = 0.032) and aortic angulation (OR: 1.07; P = 0.035) were independent predictors of device success.</p><p><strong>Conclusions: </strong>NCPI strategy could be a general method used in TAVR with a self-expanding valve for patients with PNAR, which had a higher device success rate and lower rate of complications than the conventional method.</p>","PeriodicalId":73529,"journal":{"name":"JACC. Asia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144327984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Invasive Versus Echocardiographic Aortic Valve Gradients Pre and Post Balloon-Expandable TAV-in-TAV for Failed TAVR Prosthesis","authors":"Luai Madanat MD ,&nbsp;Ivan D. Hanson MD ,&nbsp;Ahmad Jabri MD ,&nbsp;Brian Renard MD ,&nbsp;Amr E. Abbas MD","doi":"10.1016/j.jacasi.2025.02.016","DOIUrl":"10.1016/j.jacasi.2025.02.016","url":null,"abstract":"","PeriodicalId":73529,"journal":{"name":"JACC. Asia","volume":"5 6","pages":"Pages 814-816"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143993345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Full Issue PDF","authors":"","doi":"10.1016/S2772-3747(25)00251-0","DOIUrl":"10.1016/S2772-3747(25)00251-0","url":null,"abstract":"","PeriodicalId":73529,"journal":{"name":"JACC. Asia","volume":"5 6","pages":"Pages I-CXXIII"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144203386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Body Mass Index in Patients With Cardiogenic Shock Requiring Microaxial Flow Pump","authors":"Yuki Katagiri MD, PhD ,&nbsp;Yutaro Kasai MD ,&nbsp;Mamoru Miyazaki MD ,&nbsp;Ken Kuroda MD ,&nbsp;Yuichiro Hosoi MD ,&nbsp;Kohei Ishikawa MD ,&nbsp;Hiroki Bota MD ,&nbsp;Yuki Ikeda MD, PhD ,&nbsp;Yohei Sotomi MD, PhD ,&nbsp;Kenichi Matsutani MD, PhD ,&nbsp;Kazumasa Yamasaki MD ,&nbsp;Tomoyuki Tani MD ,&nbsp;Takashi Ueda MD, PhD ,&nbsp;Seiji Yamazaki MD ,&nbsp;Shigeru Saito MD ,&nbsp;J-PVAD Investigators","doi":"10.1016/j.jacasi.2025.03.003","DOIUrl":"10.1016/j.jacasi.2025.03.003","url":null,"abstract":"<div><h3>Background</h3><div>The impact of obesity on mortality in patients with cardiogenic shock (CS) requiring microaxial flow pumps (mAFP) remains undetermined.</div></div><div><h3>Objectives</h3><div>This study investigated the effect of body mass index (BMI) on mortality in CS patients treated with mAFP.</div></div><div><h3>Methods</h3><div>Data from 3,636 consecutive CS patients treated with Impella mAFP in the J-PVAD (Japanese Registry for Percutaneous Ventricular Assist Device) nationwide prospective registry in Japan between February 2020 and December 2022 were analyzed. Patients were stratified into 5 BMI categories: underweight (&lt;18.5 kg/m²), normal weight (18.5-22.9 kg/m²), overweight (23.0-24.9 kg/m²), obesity (25.0-29.9 kg/m²), and severe obesity (≥30.0 kg/m²). Multivariate Cox regression analysis assessed the relationship between BMI and 30-day mortality.</div></div><div><h3>Results</h3><div>Crude 30-day mortality increased incrementally with higher BMI categories. Adjusted HRs for 30-day mortality (normal weight as reference) were 0.71 (95% CI [CI]: 0.56-0.90; <em>P =</em> 0.005) for underweight, 1.03 (95% CI: 0.88-1.21; <em>P =</em> 0.681) for overweight, 1.37 (95% CI: 1.19-1.57; <em>P &lt;</em> 0.001) for obesity, and 2.00 (95% CI: 1.66-2.41; <em>P &lt;</em> 0.001) for severe obesity. Patients in the underweight and severe obesity groups experienced a higher incidence of bleeding after percutaneous coronary intervention under mAFP, whereas hemolysis increased with higher BMI categories. Bleeding and hemolysis were associated with mortality only in patients who were underweight.</div></div><div><h3>Conclusions</h3><div>Higher BMI was associated with increased mortality in CS patients treated with mAFP. Although patients who were underweight demonstrated overall favorable survival outcomes, bleeding and hemolysis contributed to mortality in this group. Further research is needed to explore whether a BMI-based approach can improve clinical outcomes. (Japanese registry for Percutaneous Ventricular Assist Device; <span><span>UMIN000033603</span><svg><path></path></svg></span>)</div></div>","PeriodicalId":73529,"journal":{"name":"JACC. Asia","volume":"5 6","pages":"Pages 771-783"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143712403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Drug-Coated Balloons-Based Intervention for Coronary Artery Disease","authors":"Ae-Young Her MD, PhD ,&nbsp;Wan Azman Wan Ahmad MD, PhD ,&nbsp;Liew Houng Bang MD ,&nbsp;Ong Tiong Kiam MD ,&nbsp;Amin Ariff Nuruddin MD ,&nbsp;I-Chang Hsieh MD ,&nbsp;Ho Hee Hwa MD ,&nbsp;Shaiful Azmi Yahaya MD ,&nbsp;Qiang Tang MD ,&nbsp;Jung-Cheng Hsu MD ,&nbsp;ChunGuang Qiu MD ,&nbsp;Jie Qian MD ,&nbsp;Rosli Mohd Ali MD ,&nbsp;Eun-Seok Shin MD, PhD","doi":"10.1016/j.jacasi.2025.02.017","DOIUrl":"10.1016/j.jacasi.2025.02.017","url":null,"abstract":"<div><div>Drug-coated balloons (DCBs) provide a stent-free alternative, reducing risks like stent thrombosis and in-stent restenosis and the need for prolonged dual antiplatelet therapy. Recent studies show that DCBs can be effective and safe across various coronary artery diseases (CADs) when lesions are adequately prepared. Specifically, all coronary lesions are treated using the provisional approach, where active lesion preparation is followed by DCB or drug-eluting stent treatment, depending on the results. This approach means DCB is considered the default device before initiating intervention, with efforts focused on obtaining adequate lesion preparation. Depending on the result, DCB or drug-eluting stent is selected, which is termed DCB-based percutaneous coronary intervention. Therefore, this second report of the Asia-Pacific Consensus Group provides practical guidelines (DCB-based percutaneous coronary intervention) based on the latest evidence for DCB treatment in CAD and aims to expand its application across various CADs, facilitating its effective use in real-world clinical practice.</div></div>","PeriodicalId":73529,"journal":{"name":"JACC. Asia","volume":"5 6","pages":"Pages 701-717"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143999743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the BMI-Outcome Relationship in Cardiogenic Shock","authors":"Kentaro Ejiri MD, PhD ,&nbsp;Shun Kohsaka MD, PhD","doi":"10.1016/j.jacasi.2025.04.006","DOIUrl":"10.1016/j.jacasi.2025.04.006","url":null,"abstract":"","PeriodicalId":73529,"journal":{"name":"JACC. Asia","volume":"5 6","pages":"Pages 784-785"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144203384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation of High Ischemic and Bleeding Risk Criteria of European Guidelines in Peripheral Arterial Disease","authors":"Kayo Yamamoto MD ,&nbsp;Yuichi Saito MD ,&nbsp;Yuji Ohno MD ,&nbsp;Norikiyo Oka MD ,&nbsp;Masayuki Takahara MD ,&nbsp;Sakuramaru Suzuki MD ,&nbsp;Raita Uchiyama MD ,&nbsp;Masahiro Suzuki MD ,&nbsp;Tadahiro Matsumoto MD ,&nbsp;Yo Iwata MD ,&nbsp;Yoshio Kobayashi MD","doi":"10.1016/j.jacasi.2025.01.018","DOIUrl":"10.1016/j.jacasi.2025.01.018","url":null,"abstract":"<div><h3>Background</h3><div>The 2024 European Society of Cardiology (ESC) guidelines for peripheral arterial disease (PAD) propose the dedicated high ischemic risk (HIR) and high bleeding risk (HBR) criteria.</div></div><div><h3>Objectives</h3><div>The purpose of this study was to validate the ESC-HIR and HBR criteria using real-world data.</div></div><div><h3>Methods</h3><div>From January 2019 to December 2022, this multicenter retrospective registry included 824 patients undergoing endovascular treatment for aortoiliac and femoropopliteal PAD. The ESC-HIR criteria include previous amputation, critical limb-threatening ischemia, previous revascularization, high-risk comorbidities (heart failure, diabetes, polyvascular disease), and estimated glomerular filtration rate &lt;60 mL/min/1.73 m², while the ESC-HBR criteria include dialysis or renal impairment (estimated glomerular filtration rate &lt;15 mL/min/1.73 m²), acute coronary syndrome &lt;30 days, history of stroke or transient ischemic attack, and active or clinically significant bleeding. Although patients were initially divided into 4 groups according to the presence or absence of HIR and HBR, patients with HBR and no HIR were excluded caused by the small sample size (n = 2). Major adverse cardiovascular and limb events and bleedings were evaluated.</div></div><div><h3>Results</h3><div>Of the 822 patients, 62 (7.5%), 467 (56.8%), and 293 (35.6%) were grouped in the HIR (−)/HBR (−), HIR (+)/HBR (−), and HIR (+)/HBR (+). During the median follow-up period of 726 days, major adverse cardiovascular and limb events occurred in 0%, 9.5%, and 16.4% among the 3 groups <em>(P =</em> 0.005). The incidence of major bleeding events was 4.8%, 2.4%, and 6.8%, respectively <em>(P =</em> 0.009).</div></div><div><h3>Conclusions</h3><div>The ESC-HIR and HBR criteria successfully stratified ischemic and bleeding risks in patients with PAD undergoing endovascular treatment.</div></div>","PeriodicalId":73529,"journal":{"name":"JACC. Asia","volume":"5 6","pages":"Pages 744-754"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144044818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nonadherence to Medication","authors":"Jeehoon Kang MD, PhD ,&nbsp;Jin-Eun Song MD","doi":"10.1016/j.jacasi.2025.05.001","DOIUrl":"10.1016/j.jacasi.2025.05.001","url":null,"abstract":"","PeriodicalId":73529,"journal":{"name":"JACC. Asia","volume":"5 6","pages":"Pages 769-770"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144203499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing the Tools for Assessing Frailty","authors":"Terence J. Quinn MD, MBChB (Hons), Bsc (Hons)","doi":"10.1016/j.jacasi.2025.03.006","DOIUrl":"10.1016/j.jacasi.2025.03.006","url":null,"abstract":"","PeriodicalId":73529,"journal":{"name":"JACC. Asia","volume":"5 6","pages":"Pages 811-813"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144061247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}