JACC. Asia最新文献

{"title":"Prognostic Value of Functional Incomplete Revascularization in Patients Undergoing Valve Surgery With Coronary Artery Disease","authors":"Fang Zhang BSc ,&nbsp;Wei Gao MD, PhD ,&nbsp;Wenshuo Wang MD, PhD ,&nbsp;Runda Wu MD, PhD ,&nbsp;Yan Xia MD, PhD ,&nbsp;Jingpu Wang MD, PhD ,&nbsp;Qiyu Zhang MD, PhD ,&nbsp;Jinying Zhou MD, PhD ,&nbsp;Rende Xu MD, PhD ,&nbsp;Zhangwei Chen MD, PhD ,&nbsp;Yongxin Sun MD, PhD ,&nbsp;Shengxian Tu BSc ,&nbsp;Chunsheng Wang MD, PhD ,&nbsp;Chenguang Li MD, PhD ,&nbsp;Junbo Ge MD, PhD","doi":"10.1016/j.jacasi.2025.07.007","DOIUrl":"10.1016/j.jacasi.2025.07.007","url":null,"abstract":"<div><h3>Background</h3><div>Coronary angiography remains standard for assessing lesions in valve surgery patients with concomitant coronary artery disease.</div></div><div><h3>Objectives</h3><div>This study assessed the prognostic value of functional evaluation using quantitative flow ratio in these patients.</div></div><div><h3>Methods</h3><div>Consecutive patients undergoing valve surgery (January 2016-December 2021) with ≥1 vessel stenosis (50%-90%) were included. Patients were categorized into complete revascularization (CR) or incomplete revascularization (ICR) groups by functional and traditional anatomical criteria. The primary endpoint was major adverse cardiovascular events ([MACE]; all-cause death, myocardial infarction, unplanned revascularization, stroke).</div></div><div><h3>Results</h3><div>A total of 750 patients were enrolled in the study, and 244 (32.5%) underwent combined bypass surgery. In the entire cohort, 547 patients (72.9%) met anatomical CR criteria, and 560 patients (74.7%) met functional CR criteria. After median follow-up of 3.0 years (Q1-Q3: 2.0-5.0 years). MACE were significantly increased in the functional ICR group than that in the functional CR group (20.5% [95% CI: 15.4%-26.8%] vs 10.9% [95% CI: 8.6%-13.7%]; HR: 1.98; 95% CI: 1.26-3.11; <em>P</em>&lt;0.001). Meanwhile, no significant differences in MACE rates between the anatomical ICR group and the CR group (16.3% [95% CI: 11.8%-21.9%] vs 12.2% [95% CI: 9.8%-15.3%]; HR: 1.35; 95% CI: 0.87-2.10; <em>P</em> = 0.153). In multivariable regression analysis, functional ICR was an independent predictor for MACE (adjusted HR: 1.63; 95% CI: 1.01-2.64; <em>P</em> = 0.038) compared with functional CR.</div></div><div><h3>Conclusions</h3><div>Functional ICR in patients undergoing valve surgery with coronary artery disease is associated with increased MACE. These findings support using functional assessment to guide revascularization decisions.</div></div>","PeriodicalId":73529,"journal":{"name":"JACC. Asia","volume":"5 10","pages":"Pages 1273-1284"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144981333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characteristics of Effective Antitachycardia Pacing for Ventricular Tachycardia","authors":"Satoshi Yanagisawa MD, PhD ,&nbsp;Yasuya Inden MD, PhD ,&nbsp;Yuki Sato ,&nbsp;Ryo Watanabe MD ,&nbsp;Hiroyuki Miyazawa MD ,&nbsp;Kiichi Miyamae MD ,&nbsp;Tomoya Iwawaki MD ,&nbsp;Takayuki Goto MD ,&nbsp;Shun Kondo MD ,&nbsp;Masaya Tachi MD ,&nbsp;Masafumi Shimojo MD ,&nbsp;Yukiomi Tsuji MD, PhD ,&nbsp;Takahiro Okumura MD, PhD ,&nbsp;Toyoaki Murohara MD, PhD","doi":"10.1016/j.jacasi.2025.07.005","DOIUrl":"10.1016/j.jacasi.2025.07.005","url":null,"abstract":"<div><h3>Background</h3><div>Antitachycardia pacing (ATP) has a potential benefit for shock reduction of implantable cardioverter-defibrillator (ICD) recipients; however, its clinical utility and characteristics are unknown.</div></div><div><h3>Objectives</h3><div>This study aims to extract characteristics leading to a high ventricular tachycardia (VT) termination rate of ATP.</div></div><div><h3>Methods</h3><div>Patients who had a history of ≥1 ATP treatment episode from ICD or cardiac resynchronization therapy–defibrillator (CRTD) devices were included. All ATP treatments wherein intracardiac electrograms could be traced were reviewed. Two endpoints of VT termination were defined: type-I break (termination with 0-1 beat) and clinical endpoint of termination (≤5 beats). We assessed the characteristics associated with a high success rate of ATP using the logistic regression generalized estimating equation method.</div></div><div><h3>Results</h3><div>Of 756 recipients using high-power devices, 1,468 treatment episodes in 119 patients were analyzed. The VT rate of &lt;188 beats/min (vs ≥188 beats/min), CRTD (vs ICD), and true septum right ventricular lead position were significantly associated with high success rate of type-I break termination (generalized estimating equation success rate: 78.7% vs 64.7%, <em>P</em> = 0.011; 80.1% vs 66.5%, <em>P</em> = 0.021; and 79.8% vs 60.5%, <em>P</em> = 0.023, respectively). True septum lead position and slow VT were also independently associated with successful termination with clinical endpoint. The termination rate was highest in the right ventricular true septum position across all positions at both endpoints. The pacing QRS interval was significantly shorter in the septum group than in the nonseptum group (166.2 ± 21.9 ms vs 198.7 ± 26.5 ms; <em>P</em> &lt; 0.001).</div></div><div><h3>Conclusions</h3><div>True septum lead position, in addition to slow VT and CRTD, may be key to high ATP termination success.</div></div>","PeriodicalId":73529,"journal":{"name":"JACC. Asia","volume":"5 10","pages":"Pages 1329-1343"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144981344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exercise Capacity for the Window of Atrial Fibrillation Prevention","authors":"Yoshihiro Miyamoto MD, PhD","doi":"10.1016/j.jacasi.2025.07.018","DOIUrl":"10.1016/j.jacasi.2025.07.018","url":null,"abstract":"","PeriodicalId":73529,"journal":{"name":"JACC. Asia","volume":"5 10","pages":"Pages 1357-1358"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145007005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Paychecks and Pillow Talk","authors":"Sheryl L. Chow PharmD","doi":"10.1016/j.jacasi.2025.08.010","DOIUrl":"10.1016/j.jacasi.2025.08.010","url":null,"abstract":"","PeriodicalId":73529,"journal":{"name":"JACC. Asia","volume":"5 10","pages":"Pages 1386-1388"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145236104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coronary Artery Disease in Patients With Valvular Heart Disease","authors":"Fuk Kei Fong MBBS,&nbsp;Kent Chak-yu So MBChB","doi":"10.1016/j.jacasi.2025.08.001","DOIUrl":"10.1016/j.jacasi.2025.08.001","url":null,"abstract":"","PeriodicalId":73529,"journal":{"name":"JACC. Asia","volume":"5 10","pages":"Pages 1285-1287"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145236166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing South Asian Representation in Cardiovascular Trials","authors":"S. Raquel Ramos PhD ,&nbsp;Nishita Pondugula MD, MS ,&nbsp;Mohamed Boutjdir PhD","doi":"10.1016/j.jacasi.2025.08.011","DOIUrl":"10.1016/j.jacasi.2025.08.011","url":null,"abstract":"","PeriodicalId":73529,"journal":{"name":"JACC. Asia","volume":"5 10","pages":"Pages 1257-1259"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145236171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Forecasting Atherosclerotic Cardiovascular Disease in South Asia Until 2040","authors":"Antoinette Cotton ,&nbsp;Pedro RVO Salerno MD ,&nbsp;Zhuo Chen PhD ,&nbsp;Salim Virani MD ,&nbsp;Naveed Sattar MD ,&nbsp;Sanjay Rajagopalan MD ,&nbsp;Salil V. Deo MD","doi":"10.1016/j.jacasi.2025.06.014","DOIUrl":"10.1016/j.jacasi.2025.06.014","url":null,"abstract":"<div><h3>Background</h3><div>Atherosclerotic cardiovascular disease (ASCVD) disproportionately impacts low-middle income countries, such as those in South Asia and understanding future ASCVD rates can inform public policy.</div></div><div><h3>Objectives</h3><div>This study aimed to project the burden of ASCVD in South Asia till 2040.</div></div><div><h3>Methods</h3><div>Yearly ischemic heart disease (IHD), stroke, and peripheral artery disease (PAD) counts for South Asia (Afghanistan, Bangladesh, Bhutan, India, the Maldives, Nepal, Pakistan, and Sri Lanka) and mid-year population were obtained from Global Burden of Disease (1990-2021) in 5-year age brackets (40-79 years) and estimated mid-year national population (2022-2040) was collected. Age-adjusted prevalence (aaPR) and mortality rate (per 100,000) were projected with Bayesian age-period-cohort models in South Asia (overall, males, and females); trends were reported as the estimated annual percent change (EAPC).</div></div><div><h3>Results</h3><div>Between 2021 and 2040, the IHD aaPR in South Asia was projected to increase (2021: 9434.6 [95% CI: 9,432.1-9,437.1], 2040: 9,846.6 [95% CI: 8,800.0-10,893.3], EAPC: 0.23% [95% CI: 0.08%-0.37%]) because of increased rates among females (EAPC: 1.16%; 95% CI: 1%-1.32%). The overall IHD age-adjusted mortality rate will reduce (2021: 254.7 [95% CI: 254.3-255.1), 2040: 224.0 [95% CI: 166.5-281.6), EAPC: −0.67% [95% CI: −1.61% to 0.27%]) but may increase in females (EAPC: 1.16%; 95% CI: 1%-1.32%). Stoke aaPR in South Asia is projected to increase slightly (2021: 1,065.5 [95% CI: 1,064.7-1,066.4], 2040: 1,074.6 [95% CI: 953.7-1,195.5]). The PAD aaPR is projected to increase (2021: 1809.5 [95% CI: 1,808.5-1,810.6], 2040: 1,879.5 [95% CI: 1,684.9-2,074.0], EAPC: 0.26% [95% CI: 0.04%-0.47%]) because of increased rates in females (EAPC: 0.29%; 95% CI: −0.01% to 0.59%).</div></div><div><h3>Conclusions</h3><div>IHD and PAD prevalence rates are projected to increase in South Asia with a disproportionate increase among females.</div></div>","PeriodicalId":73529,"journal":{"name":"JACC. Asia","volume":"5 10","pages":"Pages 1359-1368"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144981247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-Term Outcomes of Digital Cardiac Rehabilitation","authors":"Dilip Kumar MD, DM ,&nbsp;Prakash Kumar Hazra MD, DM, DNB ,&nbsp;Chetan H. Gharat MD","doi":"10.1016/j.jacasi.2025.08.007","DOIUrl":"10.1016/j.jacasi.2025.08.007","url":null,"abstract":"<div><div>Cardiac rehabilitation (CR) is a medically supervised program for patients with cardiovascular disease that aims to improve physical activity, health outcomes, psychological well-being, and quality of life. Traditional center-based CR faces challenges such as limited accessibility, high travel costs, and scheduling conflicts. Digital tools like mobile applications, videoconferencing, and artificial intelligence-based interventions offer potential solutions. This review investigates the long-term effectiveness of digital CR, considering the digital tools used, their design, and their impact over time. It also examines factors influencing the effectiveness of digital CR, including digital literacy, data security, patient adherence, lack of internet connectivity or smartphone access, and unfamiliarity with technology. Although digital interventions can be effective alternatives to center-based CR, addressing these challenges is essential for sustainable care. Overall, the study highlights the positive impact of digital CR on health outcomes and quality of life for patients with cardiovascular disease.</div></div>","PeriodicalId":73529,"journal":{"name":"JACC. Asia","volume":"5 10","pages":"Pages 1225-1238"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145236164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Obesity-Related Asian Patients With Heart Failure With Preserved Ejection Fraction","authors":"Kazuki Kagami MD, PhD ,&nbsp;Naoki Yuasa MD ,&nbsp;Tomonari Harada MD, PhD ,&nbsp;Toru Kondo MD, PhD ,&nbsp;Tsukasa Murakami MD, PhD ,&nbsp;Satoshi Yoshino MD, PhD ,&nbsp;Eijiro Yamada MD, PhD ,&nbsp;Naoki Wada MD, PhD ,&nbsp;Hideki Ishii MD, PhD ,&nbsp;Masaru Obokata MD, PhD","doi":"10.1016/j.jacasi.2025.07.017","DOIUrl":"10.1016/j.jacasi.2025.07.017","url":null,"abstract":"","PeriodicalId":73529,"journal":{"name":"JACC. Asia","volume":"5 10","pages":"Pages 1389-1391"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145236315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Full Issue PDF","authors":"","doi":"10.1016/S2772-3747(25)00479-X","DOIUrl":"10.1016/S2772-3747(25)00479-X","url":null,"abstract":"","PeriodicalId":73529,"journal":{"name":"JACC. Asia","volume":"5 10","pages":"Pages I-CLXXVII"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145236316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}