Vamala Guillavogui, D. Sylla, F. Sakadi, S. Diawara, Nestor Onikoyamou, Abdel-madjid Zakaria Zakaria, Kézély Béavogui, A. Cissé
{"title":"Stroke in Sub-saharan Africa: Observations from Donka National Hospital","authors":"Vamala Guillavogui, D. Sylla, F. Sakadi, S. Diawara, Nestor Onikoyamou, Abdel-madjid Zakaria Zakaria, Kézély Béavogui, A. Cissé","doi":"10.11648/j.ijbecs.20210704.12","DOIUrl":"https://doi.org/10.11648/j.ijbecs.20210704.12","url":null,"abstract":"","PeriodicalId":73426,"journal":{"name":"International journal of biomedical engineering and clinical science","volume":"47 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78013235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Problem of Early Surgical Revisions After Abdominal Surgery, Study About 83 Cases Recorded in Bangui, Central African Republic","authors":"Doui Doumgba Antoine, P. Germain, Damassara Kokonga Innocent, Ngboko Mirotiga Pétula Anicette","doi":"10.11648/j.ijbecs.20210704.13","DOIUrl":"https://doi.org/10.11648/j.ijbecs.20210704.13","url":null,"abstract":"","PeriodicalId":73426,"journal":{"name":"International journal of biomedical engineering and clinical science","volume":"105 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80910473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anne M. P. Michalek, Jonna Bobzien, Victor A Lugo, Chung-Hao Chen, A. Bruhn, M. Giannakos, Anne M. P. Michalek
{"title":"Using Eye Tracking to Explore Visual Attention in Adolescents With Autism Spectrum Disorder","authors":"Anne M. P. Michalek, Jonna Bobzien, Victor A Lugo, Chung-Hao Chen, A. Bruhn, M. Giannakos, Anne M. P. Michalek","doi":"10.4018/IJBCE.2021010101","DOIUrl":"https://doi.org/10.4018/IJBCE.2021010101","url":null,"abstract":"Video social stories are used to facilitate understanding of social situations for adolescents with autism spectrum disorder (ASD). This study explored the use of eye tracking technology to understand how adolescents with and without ASD visually attend to video social story content and whether visual attention is related to content comprehension. Six adolescents, with and without ASD, viewed a video social story of visiting a dental office. Eye gaze metrics, including fixation duration and count, and visit duration were collected to measure visual attention, and a knowledge assessment was administered for comprehension. Results indicated adolescents with ASD fixated and maintained visual attention at rates lower than peers without ASD. Adolescents with ASD scored higher (M=77.78) than peers without ASD (M=72.22) on the assessment indicating no relationship between eye gaze metrics and knowledge accuracy. Impact and implications of visual image type on frequency and duration of visual attention generated by participants is discussed.","PeriodicalId":73426,"journal":{"name":"International journal of biomedical engineering and clinical science","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75403659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Abroudi, Amir Ganji Fard, G. Dadashizadeh, Omid Gholami, D. Mahdian
{"title":"Antiproliferative Effects of Ferula assa-foetida’s Extract on PC12 and MCF7 Cancer Cells","authors":"M. Abroudi, Amir Ganji Fard, G. Dadashizadeh, Omid Gholami, D. Mahdian","doi":"10.11648/J.IJBECS.20200603.12","DOIUrl":"https://doi.org/10.11648/J.IJBECS.20200603.12","url":null,"abstract":"Background: Ferula assa-foetida is a herbaceous plant of the Umbelliferae family having a broad spectrum of biological activities such as antiseptic, antibacterial, anti-inflammation, and, anti-tumor activity against a wide range of cancers. Among these features, antitumor activity has become more important in recent years and it still demands more investigations to address the underlying mechanisms. Purpose: This current study was conducted to evaluate the anti-proliferative effect of Ferula assa-foetida on PC12 and MCF7 cells as well as examining its mechanisms. Materials and Methods: Cells were cultured in DMEM medium with 10% fetal bovine serum, 100 units/ml penicillin, and 100 µg/ml streptomycin. Cells incubated with different concentrations of the ethanolic extract of Ferula assa-foetida. Notably, cytotoxicity and apoptosis assay were measured by MTT and PI staining, respectively. Results: The MTT results showed that the ethanolic extract of Ferula assa-foetida in concentrations of 10, 7, 5, and 2.5 μM on both PC12 and MCF7 cells had a significant effect in cell viability and apoptosis induction in comparison to control group. Conclusion: In this study, it was determined that Ferula assa-fetida through the induction of apoptosis prevented the growth of PC12 and MCF7 cells and made a reduction in cell viability with different concentrations in a time- and dose-dependent manner. However, more studies are needed to reveal the mechanisms of Ferula assa-foetida’s extract in apoptosis induction.","PeriodicalId":73426,"journal":{"name":"International journal of biomedical engineering and clinical science","volume":"71 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79989534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Forecasting the Number of Coronavirus (COVID-19) Cases in Ethiopia Using Exponential Smoothing Times Series Model","authors":"T. Abebe","doi":"10.1101/2020.06.29.20142489","DOIUrl":"https://doi.org/10.1101/2020.06.29.20142489","url":null,"abstract":"The main objective of this study is to forecast COVID-19 case in Ethiopiausing the best-fitted model. The time series data of COVID-19 case in Ethiopia from March 14, 2020 to June 05, 2020 were used.To this end, exponential growth, single exponential smoothing method, and doubleexponential smoothing methodwere used. To evaluate the forecasting performance of the model, root mean sum of square error was used. The study showed that double exponential smoothing methods was appropriate in forecasting the future number ofCOVID-19 cases in Ethiopia as dictated by lowest value of root mean sum of square error. The forecasting model shows that the number of coronavirus cases in Ethiopia grows exponentially. The finding of the results would help the concerned stakeholders to make the right decisions based on the information given on forecasts.","PeriodicalId":73426,"journal":{"name":"International journal of biomedical engineering and clinical science","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87268455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Disease Patterns and Drugs Load of the ICU Patients in a Tertiary Level Teaching Hospital","authors":"K. C. Shaha, A. Sharmin, R. Karim, B. Jyoti","doi":"10.11648/J.IJBECS.20190504.14","DOIUrl":"https://doi.org/10.11648/J.IJBECS.20190504.14","url":null,"abstract":"Objective: The objective of the present study was to investigate the disease pattern and drugs load of the ICU patients at a tertiary level teaching hospital in Mymensingh. Methods and Materials: It was a descriptive type of observational study conducted in the intensive care unit of Mymensingh Medical College Hospital, Mymensingh during the period of June 2016 to December 2016. Purposive sampling was adopted for collecting data. All the admitted ICU patients were included in this study. The study was approved by the institutional ethical committee. Results: Most of the patients in the ICU belonged to the elder age group >60 years and male patients were predominant than the female ones. Average duration of stay in ICU was 4.35 days. Admissions with respiratory system disorders were more common in ICU and in the present study it revealed that 31.68% of the reported cases belonged to respiratory problems. Average number of drugs per prescription was 6.46. Average number of anti-microbial drugs per prescription was 1.38. Conclusion: Respiratory system related admissions were common in ICU. The average number of drugs per prescription was less than the other studies. Prescription protocols need to be addressed to guide appropriate use of drugs in the ICU setting.","PeriodicalId":73426,"journal":{"name":"International journal of biomedical engineering and clinical science","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90203208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Review on Rational Use of Antmicrobials in Veterinary Practice","authors":"Selamawit Fentahun Ali","doi":"10.11648/J.IJBECS.20190504.13","DOIUrl":"https://doi.org/10.11648/J.IJBECS.20190504.13","url":null,"abstract":"Veterinary drugs are used as therapeutic, prophylactic and growth promotion. The review was conducted with the aim of assessing the rational use of veterinary antimicrobials. Veterinary drugs are used in livestock sector either rationally or irrationally. Rational use of veterinary drugs means sick animals receive medications appropriate to their clinical needs, in doses that meet their own individual requirements, for an adequate period, and at the lowest cost. Whereas irrational drug use are characterized by over prescription, omission, the use of inappropriate dosage, incorrect duration, misuse of drug, take unnecessary risk, over use /frequent use of drugs and not stick with withdrawal period of a drug. The review indicates veterinary drugs used irrationally due to lack of knowledgeable of healthcare providers, lack of treatment guidelines, essential drug lists and national formularies, lack of diagnostic support services such as laboratory services, self-medication and purchasing of antibiotics directly from pharmacies, street vendors or markets and inadequate supply of veterinary drugs. Irrational use of drugs leads to antimicrobial resistance which is the current global health threat to animals and human being. Hence, veterinary drugs, especially, antimicrobial agents should be prudently used, improve availability of key essential drugs on stock through good drug supply management to reduce misuse of drugs and therapeutic failure, keep the withdrawal period to safeguard the public as well the livestock from drug residual effects and development of antimicrobial resistance are recommended.","PeriodicalId":73426,"journal":{"name":"International journal of biomedical engineering and clinical science","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74666627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association of Knowledge and Attitude of Tuberculosis Among Patients in Ethiopia","authors":"Yenew Alemu Mihret","doi":"10.11648/J.IJBECS.20190504.12","DOIUrl":"https://doi.org/10.11648/J.IJBECS.20190504.12","url":null,"abstract":"Background: Tuberculosis is a disease of poverty, mainly affecting young adults in their most productive years. The aim of this study was to identify the association of knowledge and attitude of Tuberculosis in Ethiopia and to study the relationship between TB and independent variables. The source of data is obtained from 2011 EDHS. During the analysis stage, SPSS version 23, Stata version 14 and Microsoft-Excel are used as tools of analysis. Out of 14,104 households, only 4.2% households did not heard about TB. In general education level, current marital status, region and wealth index are significant factor to association of knowledge and attitude of tuberculosis among patients in Ethiopia.","PeriodicalId":73426,"journal":{"name":"International journal of biomedical engineering and clinical science","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84126896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Iteku, Ornella Mbayi, G. Bongo, P. K. Mutwale, J. M. Wambale, E. Lengbiye, C. L. Inkoto, Samy Ngunde Te Ngunde, K. Ngbolua
{"title":"Phytochemical Analysis and Assessment of Antibacterial and Antioxidant Activities of Phytolacca dodecandra L. Herit Leaf Extracts (Phytolaccaceae)","authors":"J. Iteku, Ornella Mbayi, G. Bongo, P. K. Mutwale, J. M. Wambale, E. Lengbiye, C. L. Inkoto, Samy Ngunde Te Ngunde, K. Ngbolua","doi":"10.11648/J.IJBECS.20190503.11","DOIUrl":"https://doi.org/10.11648/J.IJBECS.20190503.11","url":null,"abstract":"From times immemorial, medicinal plants have been used to relieve and cure human diseases. Currently, the control of bacterial infections is becoming complex due to the concern of antibiotic resistance, which has been a significant global health problem. The aim of this work was to determine the phytochemical composition as well as to assess the bioactivities of Phytolacca dodecandra leaf extracts. The leaves of P. dodecandra were collected in January 2017 at Yakoma city, Nord-Ubangi, DRC. Three bacterial strains namely Staphylococcus aureus ATCC 25923, Escherichia coli ATCC 8739 and Pseudomonas aeroginosa ATCC 9027 were used for the assessment of the antibacterial activity. The qualitative and quantitative phytochemical screening were used for compound identification. The antioxidant activity was assessed using ABTS and DPPH scavenging tests while the antibacterial activity was performed using the diffusion method. The findings show that leaves of this plant are rich in flavonoids, anthocyanins, terpenoids and irrioids. The inhibitory concentration 50 (IC50) values obtained in the ATBS test are lower than those of the DPPH test. The antibacterial activity of this plant was low against the three strains used. These in vitro findings show that medicinal plants have very important biological properties that have many applications in various fields such as medicine, pharmacy and agriculture.","PeriodicalId":73426,"journal":{"name":"International journal of biomedical engineering and clinical science","volume":"72 7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78051277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bacterial Contamination of Hospital Equipments in Two Tertiary Health Facilities in Central Nigeria and Their Corresponding Susceptibility to Antimicrobial Agents","authors":"Adamu Muktar Owuna, Owuna Jibril Egwu, Y. Hajara, Azamu Ibaku Gowon","doi":"10.11648/J.IJBECS.20190502.13","DOIUrl":"https://doi.org/10.11648/J.IJBECS.20190502.13","url":null,"abstract":"Hospital is a major avenue for the spread of infectious diseases known as nosocomial infections. This study investigated the bacteria that colonize hospital equipments at the Federal Medical Centre and Nasarawa State University Clinic Keffi. Swab samples of different hospital equipments were collected and examined using standard microbiological techniques. Cultural features indicates the presence of the following bacteria; Escherichia coli, Klebsiella spp., Pseudomonas spp., Staphylococcus aureus and Enterobacter spp. The mean bacterial load from NSUK clinic equipments (×104cfu/ml) were 0.32, 0.18, 0.19 and 0.1 for total viable, total coliform, total fecal coliform and staphylococcus aureus count respectively, while the mean bacterial load in FMC (×104cfu/ml) was 1.254, 0.347 and 0.283 for total viable count, coliform count and faecal coliform count accordingly. Frequency of occurrence of the bacteria isolates in FMC is in the order: Escherichia coli (50.0%)>Enterobacter spp. (30.0%)>Klebsiella spp. and Pseudomonas spp. (20.0%)>Staphylococcus aureus (0.0%); while that of NSUK clinic is in the order: Escherichia coli (50.0%)>Pseudomonas spp. (30.0%)>Staphylococcus aureus (10.0%), while Klebsiella spp. and Enterobacter spp. were not isolated at NSUK clinic. The antibiotic susceptibility pattern of the bacteria showed Pseudomonas spp. to be completely susceptible to Augmentin, Gentamicin, Chloramphenicol and Ciprofloxacin (100.0% each), while E. coli showed some degree of susceptibility to Streptomycin (44.4%), Ciprofloxacin and Perfloxacin (33.3%), Gentamicin and Sparfloxacin (22.2%), Augmentin, Ofloxacin, Septrin and Chloramphenicol (11.1%), but completely resistant to Amoxicillin. Klebsiella spp. and Enterobacter spp. were resistant to all the antibiotics tested, except for Streptomycin which they displayed high susceptibility of 100.0% and 66.7% for Klebsiella spp. and Enterobacter spp. respectively. Staphylococcus aureus was found to be resistant completely against all the antibiotics tested. Hence, it is pertinent to embrace hand hygiene so as to minimize the risk of acquiring nosocomial infections due to contaminated hospital equipments.","PeriodicalId":73426,"journal":{"name":"International journal of biomedical engineering and clinical science","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84631561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}