IJID regions最新文献

{"title":"Epidemiology, microbiological, clinical characteristics, and outcome of Burkholderia cepacia complex infections in non-cystic fibrosis adult patients from Qatar","authors":"Tawheeda Ibrahim ,&nbsp;Tasneem A. Abdallah ,&nbsp;Ahmed Abdallah ,&nbsp;Rabia Qazi ,&nbsp;Abeir Alimam ,&nbsp;Hashim Mohammad ,&nbsp;Faiha Eltayeb ,&nbsp;Joanne Daghfal ,&nbsp;Maisa Ali ,&nbsp;Hamad Abdel Hadi","doi":"10.1016/j.ijregi.2024.03.010","DOIUrl":"10.1016/j.ijregi.2024.03.010","url":null,"abstract":"<div><h3>Objectives</h3><p><em>Burkholderia</em> species infections are associated with diverse and challenging clinical presentations because of distinct virulence and antimicrobial resistance factors. The study aims to evaluate the epidemiology, microbiological, and clinical outcomes of <em>Burkholderia cepacia</em> complex (Bcc) infections in non-cystic fibrosis (CF) patients from Qatar.</p></div><div><h3>Methods</h3><p>A retrospective study was conducted on adult patients across all hospitals at Hamad Medical Corporation between January 2012 and December 2018 to evaluate clinically relevant Bcc in non-CF adult patients.</p></div><div><h3>Results</h3><p>Over 7 years, 72 episodes of <em>Burkholderia</em> species infections were recorded, 64 were secondary to Bcc primarily affecting males (78.12%) with a mean age of 53 years, from the Middle and Southeastern region (92.2%) affected predominantly by diabetes mellitus (34.4%), chronic kidney (23.4%), coronary heart (20.3%), and hypertensive diseases (17.2%) while recent hospitalization and admission to critical care were evident in 45.3% and 93.8% of cases, respectively. Main infection sites were urinary (43.8%) and respiratory (29.7%) with associated bacteremia recorded in 26.6% of cases. Microbiological characteristics demonstrated high-level resistance profiles leading to delayed microbiological clearance in case of bacteremia (61%) and management with multiple therapeutic agents (range 4-6) resulting in disease resolution in 90.6% of cases with observed 30-day mortality of 7.8%.</p></div><div><h3>Conclusions</h3><p><em>B. cepacia</em> infections are infrequent, recorded mainly in middle-aged males with chronic comorbidities presenting as urinary, respiratory, and bacteremia associated with hospitalization, admission to critical care, and invasive procedures. High-level antimicrobial resistance is observed necessitating multiple therapeutic agents and suboptimal bacteriological clearance.</p></div>","PeriodicalId":73335,"journal":{"name":"IJID regions","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772707624000262/pdfft?md5=af8d63e3aae1dff75269664f4de535e1&pid=1-s2.0-S2772707624000262-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140400146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Increased threat of urban arboviral diseases from Aedes aegypti mosquitoes in Colombia","authors":"Rosa Margarita Gélvez Ramírez ,&nbsp;Chloé Bohers ,&nbsp;Laurence Mousson ,&nbsp;Yoann Madec ,&nbsp;Marie Vazeille ,&nbsp;Géraldine Piorkowski ,&nbsp;Sara Moutailler ,&nbsp;Francisco J Diaz ,&nbsp;Guillermo Rúa-Uribe ,&nbsp;Luis Angel Villar ,&nbsp;Xavier de Lamballerie ,&nbsp;Anna-Bella Failloux","doi":"10.1016/j.ijregi.2024.100360","DOIUrl":"10.1016/j.ijregi.2024.100360","url":null,"abstract":"<div><h3>Objectives</h3><p>Our study targets the potential of the local urban mosquito <em>Aedes aegypti</em> to experimentally transmit chikungunya virus (CHIKV), dengue virus (DENV), yellow fever virus (YFV), and Zika virus (ZIKV).</p></div><div><h3>Methods</h3><p>We collected eggs and adults of <em>Ae. aegypti</em> in Medellín, Colombia (from February to March 2020) for mosquito experimental infections with DENV, CHIKV, YFV and ZIKV and viral detection using the BioMark Dynamic arrays system.</p></div><div><h3>Results</h3><p>We show that <em>Ae. aegypti</em> from Medellín was more prone to become infected, to disseminate and transmit CHIKV and ZIKV than DENV and YFV.</p></div><div><h3>Conclusions</h3><p>Thus, in Colombia, chikungunya is the most serious threat to public health based on our vector competence data.</p></div>","PeriodicalId":73335,"journal":{"name":"IJID regions","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772707624000316/pdfft?md5=9cb30555a5846cd4305ecf79b0f998ae&pid=1-s2.0-S2772707624000316-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140277026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characterization of human respiratory syncytial virus in children with severe acute respiratory infection before and during the COVID-19 pandemic","authors":"Paul Simusika ,&nbsp;Michiko Okamoto ,&nbsp;Clyde Dapat ,&nbsp;Walter Muleya ,&nbsp;Moffat Malisheni ,&nbsp;Sikandar Azam ,&nbsp;Takeaki Imamura ,&nbsp;Mayuko Saito ,&nbsp;Innocent Mwape ,&nbsp;Evans Mpabalwani ,&nbsp;Mwaka Monze ,&nbsp;Hitoshi Oshitani","doi":"10.1016/j.ijregi.2024.03.009","DOIUrl":"10.1016/j.ijregi.2024.03.009","url":null,"abstract":"<div><h3>Objectives</h3><p>Annual outbreaks of human respiratory syncytial virus (HRSV) are caused by newly introduced and locally persistent strains. During the COVID-19 pandemic, global and local circulation of HRSV significantly decreased. This study was conducted to characterize HRSV in 2018-2022 and to analyze the impact of COVID-19 on the evolution of HRSV.</p></div><div><h3>Design/methods</h3><p>Combined oropharyngeal and nasopharyngeal swabs were collected from children hospitalized with severe acute respiratory infection at two hospitals in Zambia. The second hypervariable region of the attachment gene G was targeted for phylogenetic analysis.</p></div><div><h3>Results</h3><p>Of 3113 specimens, 504 (16.2%) were positive for HRSV, of which 131 (26.0%) and 66 (13.1%) were identified as HRSVA and HRSVB, respectively. In early 2021, an increase in HRSV was detected, caused by multiple distinct clades of HRSVA and HRSVB. Some were newly introduced, whereas others resulted from local persistence.</p></div><div><h3>Conclusions</h3><p>This study provides insights into the evolution of HRSV, driven by global and local circulation. The COVID-19 pandemic had a temporal impact on the evolution pattern of HRSV. Understanding the evolution of HRSV is vital for developing strategies for its control.</p></div>","PeriodicalId":73335,"journal":{"name":"IJID regions","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772707624000250/pdfft?md5=7618114dadc0be37f38097c358e8bf91&pid=1-s2.0-S2772707624000250-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140279042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiology of rare bacterial, parasitic, and fungal pathogens in India","authors":"Shweta Sharma ,&nbsp;Varun Krishnaswamy ,&nbsp;Rini Chaturvedi ,&nbsp;Amit Sharma","doi":"10.1016/j.ijregi.2024.100359","DOIUrl":"https://doi.org/10.1016/j.ijregi.2024.100359","url":null,"abstract":"<div><p>Rare human pathogens are infrequently observed clinically but can lead to undiagnosed infections, delays in treatment, severe complications, including death. Traditional diagnostic tools cannot routinely detect rare infections in public health settings. This study focuses on the incidence and outcomes of rare pathogenic microorganisms over 13 years (2010-2022) using PubMed database to obtain epidemiological data on rare bacterial, parasitic, and fungal infections in hospitals throughout India. A total of 974 articles were screened using case studies, datasets, comments, classical articles, letters, editorials, observational studies, and meta-analyses. Our analysis identified 28 rare bacteria, six parasites, and five fungal species infections in India. Fatal cases were associated with rare bacterial and fungal infections, including two from pan-drug–resistant bacteria (both from the <em>Myroides</em> genus). A total of 10 bacterial species displayed multi-drug resistance; one was extensively drug-resistant, and eight remained unclassified. Of the 83 patients with these rare infections, the mortality was ∼8.4% (seven of 83). Considering drug resistance and high mortality, prompt diagnosis of rare pathogens is crucial to controlling their spread. An increased awareness within the Indian health care system focusing on diagnostics, record keeping, and data sharing will be necessary to enhance surveillance.</p></div>","PeriodicalId":73335,"journal":{"name":"IJID regions","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772707624000304/pdfft?md5=a08e7da7073de6e1c726f7118c98e941&pid=1-s2.0-S2772707624000304-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140549734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiology, clinical presentation, and outcome of mpox: A study of 381 cases in Saudi Arabia","authors":"Abdullah M Assiri ,&nbsp;Haleema Alserehi ,&nbsp;Musallam Yunus Abuhasan ,&nbsp;Einas Adul Aziz Khalil ,&nbsp;Mohammed Hussain Al-Thunayan ,&nbsp;Mohammed Saaban Alshehri ,&nbsp;Amirah Abdulmohsen Alrossais ,&nbsp;Abdulrahman Saeed Abudahish ,&nbsp;Abdullah Jaber Alsahafi ,&nbsp;Jaffar A. Al-Tawfiq","doi":"10.1016/j.ijregi.2024.100358","DOIUrl":"10.1016/j.ijregi.2024.100358","url":null,"abstract":"<div><h3>Objectives</h3><p>There are limited data on the clinical and epidemiological aspects of mpox in Saudi Arabia. This study investigates the characteristics of Mpox cases from May to September 2023.</p></div><div><h3>Methods</h3><p>A total of 381 cases of Mpox were included in this study, diagnosed based on a combination of clinical symptoms and laboratory testing.</p></div><div><h3>Results</h3><p>The majority of mpox cases were males (91.1%), with a mean age of (±SD) of 32.4 (±8.3) years; 356 (93.4%) did not report travel, 277 (72.7%) denied engaging in extra-marital sex, and 379 (99.5%) were not linked to secondary cases. Fever was reported in 371 (97.4%), whereas headache was present in 314 (82.4%). Cough (1.3%) and conjunctivitis (0.5%) were rare. The most commonly affected areas in terms of lesions were the palms and soles (297 cases, 78%), followed by the genitals (206 cases, 54%), face (198 cases, 52%), and mouth (160 cases, 42%). Of the 1325 identified contacts, 1134 (85.5%) were hospital contacts, and 191 (14.5%) were community contacts, and 393 (29.6%) were high-risk contact. Of the high-risk contacts, 284 (72.3%) accepted post-exposure vaccination. The genotyped samples were all subclade IIb (formerly the West Africa clade).</p></div><div><h3>Conclusions</h3><p>This study provides valuable insights into mpox characteristics in Saudi Arabia. The genome of monkeypox virus belonged to subclade IIb of the West Africa clade. Further analysis of the global tree sublineage is needed.</p></div>","PeriodicalId":73335,"journal":{"name":"IJID regions","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772707624000298/pdfft?md5=084918588ed4347cfd44002faf412a31&pid=1-s2.0-S2772707624000298-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140272899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring factors associated with Trichuris trichiura infection in school children in a high-transmission setting in Kenya","authors":"Stella Kepha ,&nbsp;Humphrey D. Mazigo ,&nbsp;Maurice R. Odiere ,&nbsp;Carlos Mcharo ,&nbsp;Th'uva Safari ,&nbsp;Paul M. Gichuki ,&nbsp;Wykcliff Omondi ,&nbsp;Florence Wakesho ,&nbsp;Alejandro Krolewiecki ,&nbsp;Rachel L. Pullan ,&nbsp;Charles S. Mwandawiro ,&nbsp;William E. Oswald ,&nbsp;Katherine E. Halliday","doi":"10.1016/j.ijregi.2024.03.007","DOIUrl":"10.1016/j.ijregi.2024.03.007","url":null,"abstract":"<div><h3>Objectives</h3><p>Kenya has implemented a national school-based deworming program, which has led to substantial decline in the prevalence of soil-transmitted helminths (STHs), although some pockets of infections remain. To effectively design an STH control program that leads to significant reductions of <em>Trichuris trichiura,</em> there is a need to understand the drivers of persistent infection despite ongoing treatment programs.</p></div><div><h3>Methods</h3><p>This study was conducted between July and September 2019 at the south coast of Kenya, using a two-stage sampling design. First, a school-based cross-sectional survey was conducted in 2265 randomly selected school children from selected schools in areas known to be endemic for <em>T. trichiura</em>. After this, we conducted a nested case-control study wherein all children positive for <em>T. trichiura</em> (142) were matched to 148 negative controls based on age and village. A household survey was then conducted with all household members of cases and controls. In addition, a subsample of 116 children found to be infected with <em>T. trichiura</em> were followed up to assess the efficacy of albendazole at day 21 post-treatment. The predictors of presence of <em>T. trichiura</em> were investigated through multilevel logistic regression, considering clustering of infection.</p></div><div><h3>Results</h3><p>Overall, 34.4% of the children were infected with at least one STH species; <em>T. trichiura</em> was the most common (28.3%), 89.1% of those with <em>T. trichiura</em> had light-intensity infections. The prevalence of <em>T. trichiura</em> was significantly higher in male children and was positively associated with younger age and number of people infected with <em>T. trichiura</em> in a household. The parasitological cure rate and egg reduction rate of <em>T. trichiura</em> were 35% and 51%, respectively. Other STHs identified were hookworm (9.6%) and <em>Ascaris lumbricoides</em> (5.7%).</p></div><div><h3>Conclusions</h3><p><em>T. trichiura</em> remains a significant public health challenge in the study area with albendazole treatment efficacy against the parasite, remaining lower than the World Health Organization–recommended thresholds. Because of the observed focal transmission of <em>T. trichiura</em> in the current area, control efforts tailored to local conditions and targeting lower implementation units should be used to achieve optimal results on transmission.</p></div>","PeriodicalId":73335,"journal":{"name":"IJID regions","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772707624000237/pdfft?md5=4268a0843390c5763bc69992bba59ef9&pid=1-s2.0-S2772707624000237-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140275294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genomic surveillance of SARS-CoV-2 in North Africa: 4 years of GISAID data sharing","authors":"Zaineb Hamzaoui ,&nbsp;Sana Ferjani ,&nbsp;Ines Medini ,&nbsp;Latifa Charaa ,&nbsp;Ichrak Landolsi ,&nbsp;Roua Ben Ali ,&nbsp;Wissal Khaled ,&nbsp;Sarra Chammam ,&nbsp;Salma Abid ,&nbsp;Lamia Kanzari ,&nbsp;Asma Ferjani ,&nbsp;Ahmed Fakhfakh ,&nbsp;Dhouha Kebaier ,&nbsp;Zoubeir Bouslah ,&nbsp;Mouna Ben Sassi ,&nbsp;Sameh Trabelsi ,&nbsp;Ilhem Boutiba-Ben Boubaker","doi":"10.1016/j.ijregi.2024.100356","DOIUrl":"10.1016/j.ijregi.2024.100356","url":null,"abstract":"<div><h3>Objectives</h3><p>This study aimed to construct geographically, temporally, and epidemiologically representative data sets for SARS-CoV-2 in North Africa, focusing on Variants of Concern (VOCs), Variants of Interest (VOIs), and Variants Under Monitoring (VUMs).</p></div><div><h3>Methods</h3><p>SARS-CoV-2 genomic sequences and metadata from the EpiCoV database via the Global Initiative on Sharing All Influenza Data platform were analyzed. Data analysis included cases, deaths, demographics, patient status, sequencing technologies, and variant analysis.</p></div><div><h3>Results</h3><p>A comprehensive analysis of 10,783 viral genomic sequences from six North African countries revealed notable insights. SARS-CoV-2 sampling methods lack standardization, with a majority of countries lacking clear strategies. Over 59% of analyzed genomes lack essential clinical and demographic metadata, including patient age, sex, underlying health conditions, and clinical outcomes, which are essential for comprehensive genomic analysis and epidemiological studies, as submitted to the Global Initiative on Sharing All Influenza Data. Morocco reported the highest number of confirmed COVID-19 cases (1,272,490), whereas Tunisia leads in reported deaths (29,341), emphasizing regional variations in the pandemic's impact. The GRA clade emerged as predominant in North African countries. The lineage analysis showcased a diversity of 190 lineages in Egypt, 26 in Libya, 121 in Tunisia, 90 in Algeria, 146 in Morocco, and 10 in Mauritania. The temporal dynamics of SARS-CoV-2 variants revealed distinct waves driven by different variants.</p></div><div><h3>Conclusions</h3><p>This study contributes valuable insights into the genomic landscape of SARS-CoV-2 in North Africa, highlighting the importance of genomic surveillance in understanding viral dynamics and informing public health strategies.</p></div>","PeriodicalId":73335,"journal":{"name":"IJID regions","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772707624000274/pdfft?md5=6d271fb9bd94efc4bb2ae5ad98bebe13&pid=1-s2.0-S2772707624000274-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140270150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of pneumococcal conjugate vaccine 13 introduction on severe lower respiratory tract infections associated with respiratory syncytial virus or influenza virus in hospitalized children in Ulaanbaatar, Mongolia","authors":"Lien Anh Ha Do ,&nbsp;Naranzul Tsedenbal ,&nbsp;Chimidregzen Khishigmunkh ,&nbsp;Bazarkhuu Tserendulam ,&nbsp;Lkhagvadorj Altanbumba ,&nbsp;Dashtseren Luvsantseren ,&nbsp;Munkhchuluun Ulziibayar ,&nbsp;Bujinlkham Suuri ,&nbsp;Dorj Narangerel ,&nbsp;Bilegtsaikhan Tsolmon ,&nbsp;Sodbayar Demberelsuren ,&nbsp;Cattram Nguyen ,&nbsp;Tuya Mungun ,&nbsp;Claire von Mollendorf ,&nbsp;Darmaa Badarch ,&nbsp;Kim Mulholland","doi":"10.1016/j.ijregi.2024.100357","DOIUrl":"10.1016/j.ijregi.2024.100357","url":null,"abstract":"<div><h3>Objectives</h3><p>Limited data indicate a beneficial effect of pneumococcal conjugate vaccines (PCVs) on respiratory syncytial virus (RSV) and influenza infections in young children. We evaluated the impact of 13-valent PCV (PCV13) introduction on the incidence of severe lower respiratory tract infections (LRTIs) associated with RSV or influenza in hospitalized children.</p></div><div><h3>Methods</h3><p>Our study was restricted to children aged &lt;2 years with arterial oxygen saturation &lt;93% and children with radiologically confirmed pneumonia nested in a pneumonia surveillance project in four districts of Ulaanbaatar city, Mongolia. We tested nasopharyngeal swabs collected on admission for RSV and influenza using quantitative reverse transcription-polymerase chain reaction. The impact of PCV13 on the incidence of LRTI outcomes associated with RSV or with influenza for the period April 2015-March 2020 was estimated. Incidence rate ratios comparing pre- and post-vaccine periods were estimated for each outcome for each district using negative binomial models and for all districts combined with a mixed-effects negative binomial model. Adjusted models accounted for seasonality. Sensitivity analyses were conducted to assess the robustness of our findings.</p></div><div><h3>Results</h3><p>Among 5577 tested cases, the adjusted incidence rate ratios showed a trend toward a reduction in RSV-associated outcomes: all LRTIs (0.77, 95% confidence interval [CI] 0.44-1.36), severe LRTIs (0.88, 95% CI 0.48-1.62), very severe LRTIs (0.76, 95% CI 0.42-1.38), and radiologically confirmed pneumonia (0.66, 95% CI 0.32-1.38) but inconsistent trends in outcomes associated with influenza.</p></div><div><h3>Conclusions</h3><p>No significant reductions were observed in any outcomes associated with RSV and influenza after PCV introduction.</p></div>","PeriodicalId":73335,"journal":{"name":"IJID regions","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772707624000286/pdfft?md5=f145956ba1a3fba96253377c1aefc50a&pid=1-s2.0-S2772707624000286-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140282546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of comorbidity on the quality of life of people who recovered from COVID-19 in Bangladesh","authors":"Md. Abdullah Saeed Khan ,&nbsp;Koustuv Dalal ,&nbsp;Mehedi Hasan ,&nbsp;Miah Md. Akiful Haque ,&nbsp;Nusrat-E-Mozid ,&nbsp;Mosharop Hossian ,&nbsp;Tajrin Rahman ,&nbsp;Ramisha Maliha ,&nbsp;Archi Mutsuddi ,&nbsp;Md. Utba Rashid ,&nbsp;Mohammad Ali Hossain ,&nbsp;Mohammad Hayatun Nabi ,&nbsp;Mohammad Delwer Hossain Hawlader","doi":"10.1016/j.ijregi.2024.03.006","DOIUrl":"10.1016/j.ijregi.2024.03.006","url":null,"abstract":"<div><h3>Objectives</h3><p>COVID-19 affects the quality of life (QoL) in a reverse way after recovery, which might be multiplied by the comorbid non-communicable diseases. This study explored the relationship between comorbidities and the QoL of people who recovered from COVID-19 in Bangladesh.</p></div><div><h3>Methods</h3><p>The cross-sectional study was conducted among 3244 participants between June 2020 and November 2020 using a pre-tested questionnaire through over-the-phone interviews. The WHOQOL-BREF was used to explore the QoL among the study participants. A multivariable linear regression model was conducted to identify the effects of the number of comorbidities on QoL scores of all four domains.</p></div><div><h3>Results</h3><p>Of 3244 patients who recovered from COVID-19, over one-third (39.4%) had one or more chronic diseases, such as hypertension, diabetes mellitus, ischemic heart disease, bronchial asthma/chronic obstructive pulmonary disease, chronic kidney disease, and cancer. Around 46.85% of the participants aged above 40 years presented with one to two chronic diseases, and 16.33% had three or more chronic diseases. Among all comorbidities, the participants with cancer and chronic kidney disease were found to have relatively lower scores in all four domains than other comorbidities. The lowest QoL scores were observed in the psychological domain. Those with three or more simultaneous chronic comorbidities had the lowest QoL score in all four domains: physical, psychological, social relationship, and environmental.</p></div><div><h3>Conclusions</h3><p>Persons who recovered from COVID-19 with comorbidities undergo a lower QoL. Therefore, special attention is required to these vulnerable groups to ensure their smooth recuperation.</p></div>","PeriodicalId":73335,"journal":{"name":"IJID regions","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772707624000225/pdfft?md5=8964a32c8e9011d157704ed4a8ffbb40&pid=1-s2.0-S2772707624000225-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140276470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigating the epidemiology and outbreaks of scabies in Japanese households, residential care facilities, and hospitals using claims data: the Longevity Improvement & Fair Evidence (LIFE) study","authors":"Yukihiro Yamaguchi,&nbsp;Fumiko Murata,&nbsp;Megumi Maeda,&nbsp;Haruhisa Fukuda","doi":"10.1016/j.ijregi.2024.03.008","DOIUrl":"10.1016/j.ijregi.2024.03.008","url":null,"abstract":"<div><h3>Objectives</h3><p>This study aimed to characterize the epidemiology of scabies and its outbreaks in Japanese households, residential care facilities (RCFs), and hospitals using claims data.</p></div><div><h3>Methods</h3><p>This descriptive epidemiological study was conducted using claims data from eight municipalities in Japan. Scabies cases were identified using a combination of recorded diagnoses and administered medications. The study period was from April 2015 to March 2019. Outbreaks were defined as ≥2 cases of scabies occurring within a calendar month at a single household, RCF, or hospital.</p></div><div><h3>Results</h3><p>We identified 857 scabies cases for analysis. The annual prevalence of scabies ranged from 40 to 67 per 100,000 beneficiaries. The annual attack rate of scabies was found to be highest in RCFs (21 per 1000 RCFs), followed by hospitals (11 per 1000 hospitals) and households (0.25 per 1000 households). The annual outbreak attack rate was also highest in RCFs (4.0 per 1000 RCFs), followed by hospitals (1.6 per 1000 hospitals) and household (0.027 per household). The patterns of outbreaks varied widely among the RCFs.</p></div><div><h3>Conclusions</h3><p>The study showcases the potential of claims data for detecting infectious disease outbreaks, which could provide valuable insight for the future management and prevention of scabies. Infection control of scabies in RCFs is crucial in aging societies.</p></div>","PeriodicalId":73335,"journal":{"name":"IJID regions","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772707624000249/pdfft?md5=b09fbcf771ab97c57a810fad5bdc27db&pid=1-s2.0-S2772707624000249-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140279659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}