Acta gastro-enterologica Belgica最新文献

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Child with protein losing enteropathy as presentation of collagenous duodenitis and eosinophilic gastroenteritis. 以胶原性十二指肠炎和嗜酸性胃肠炎为表现的失蛋白肠病患儿。
IF 1.5 4区 医学
Acta gastro-enterologica Belgica Pub Date : 2023-04-01 DOI: 10.51821/86.2.9374
K van Hoeve, M De Keukelaere, G De Hertogh, I Hoffman
{"title":"Child with protein losing enteropathy as presentation of collagenous duodenitis and eosinophilic gastroenteritis.","authors":"K van Hoeve,&nbsp;M De Keukelaere,&nbsp;G De Hertogh,&nbsp;I Hoffman","doi":"10.51821/86.2.9374","DOIUrl":"https://doi.org/10.51821/86.2.9374","url":null,"abstract":"<p><strong>Background: </strong>Collagenous duodenitis and gastritis are rare histopathological findings in children.</p><p><strong>Patients and methods: </strong>: We describe a four-year old girl, who presented with non-bloody diarrhea for two months and progressive edema with an albumin of 16g/dl.</p><p><strong>Results: </strong>The diagnosis of a protein losing enteropathy was made. Extensive investigations withheld only an infectious cause of the protein losing enteropathy (cytomegalovirus and adenovirus). However, the patients still required repetitive albumin infusions 3.5 months after onset of symptoms without spontaneous recovery. Therefore, a new endoscopic work-up was performed. Duodenal biopsies revealed collagen deposition, in association with a high number of eosinophils and mast cells throughout different parts of the gastrointestinal tract.</p><p><strong>Conclusions: </strong>The collagen deposition seems to be triggered by an eosinophilic gastrointestinal disorder. Treatment was started with amino acid-based formula, oral iron therapy, an antihistamine, and a proton pomp inhibitor that resulted in persistent normalization of serum albumin already after 1.5 weeks.</p>","PeriodicalId":7322,"journal":{"name":"Acta gastro-enterologica Belgica","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9839686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Endoscopic therapy for Bouveret syndrome, illustrated by a case report. 布韦莱特综合征的内镜治疗,附病例报告。
IF 1.5 4区 医学
Acta gastro-enterologica Belgica Pub Date : 2023-04-01 DOI: 10.51821/86.2.10503
E Hufkens, M Struyve, M Bronswijk, S van der Merwe
{"title":"Endoscopic therapy for Bouveret syndrome, illustrated by a case report.","authors":"E Hufkens,&nbsp;M Struyve,&nbsp;M Bronswijk,&nbsp;S van der Merwe","doi":"10.51821/86.2.10503","DOIUrl":"https://doi.org/10.51821/86.2.10503","url":null,"abstract":"<p><p>Bouveret syndrome is an exceptionally rare form of gallstone ileus secondary to a bilioenteric fistula, through which a voluminous gallstone can migrate into the pylorus or duodenum, thereby causing gastric outlet obstruction. In order to increase awareness, we reviewed the clinical features, diagnostic tools and management options for this uncommon entity. We specifically focus on endoscopic therapeutic options, illustrated by a case of a 73 year old woman with Bouveret syndrome, where endoscopic electrohydraulic lithotripsy was successful in relieving gastroduodenal obstruction.</p>","PeriodicalId":7322,"journal":{"name":"Acta gastro-enterologica Belgica","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9867285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Are elevated systemic bile acids involved in the pathophysiology of sarcopenia and liver injury following gastric bypass? 胆汁酸升高是否与胃旁路术后肌肉减少症和肝损伤的病理生理有关?
IF 1.5 4区 医学
Acta gastro-enterologica Belgica Pub Date : 2023-04-01 DOI: 10.51821/86.2.11517
S Bourseau, N Bozadjieva-Kramer, A Goffaux, P Baldin, F Etogo-Asse, P Trefois, N Lanthier
{"title":"Are elevated systemic bile acids involved in the pathophysiology of sarcopenia and liver injury following gastric bypass?","authors":"S Bourseau,&nbsp;N Bozadjieva-Kramer,&nbsp;A Goffaux,&nbsp;P Baldin,&nbsp;F Etogo-Asse,&nbsp;P Trefois,&nbsp;N Lanthier","doi":"10.51821/86.2.11517","DOIUrl":"https://doi.org/10.51821/86.2.11517","url":null,"abstract":"<p><p>Bariatric surgery is currently the most effective treatment for sustained weight loss in severe obesity. However, recent data describe the development of liver damage and in particular massive steatosis and cholangitis in some patients, for which certain pathophysiological mechanisms are suggested such as bacterial overgrowth, malabsorption or sarcopenia. We describe the case of a patient presenting with a new liver dysfunction 6 years after a gastric bypass. The work-up revealed sarcopenic obesity characterised by low muscle mass and low muscle function as well as elevated fasting bile acids, severe liver steatosis and cholangitis. The pathophysiology of this disease is complex and multifactorial but could include bile acid toxicity. Bile acids are increased in cases of liver steatosis, but also in cases of gastric bypass and malnutrition. In our opinion, they may contribute to the loss of muscle mass and the vicious circle observed in this situation. Treatment with enteral feeding, intravenous albumin supplementation and diuretics reversed the liver dysfunction and the patient was discharged from hospital.</p>","PeriodicalId":7322,"journal":{"name":"Acta gastro-enterologica Belgica","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9813077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nutritional optimization in liver transplant patients: from the pre-transplant setting to post-transplant outcome. 肝移植患者的营养优化:从移植前到移植后的结果。
IF 1.5 4区 医学
Acta gastro-enterologica Belgica Pub Date : 2023-04-01 DOI: 10.51821/86.2.11485
F M Trovato, F Artru
{"title":"Nutritional optimization in liver transplant patients: from the pre-transplant setting to post-transplant outcome.","authors":"F M Trovato,&nbsp;F Artru","doi":"10.51821/86.2.11485","DOIUrl":"https://doi.org/10.51821/86.2.11485","url":null,"abstract":"<p><strong>Background and study aims: </strong>malnutrition and its clinical phenotypes, sarcopenia, and frailty, are prevalent conditions that affect patients with cirrhosis awaiting liver transplantation. The link between malnutrition, sarcopenia, and frailty and a higher risk of complications or death (before and after liver transplantation) is well established. Accordingly, the optimization of nutritional status could optimize both access to liver transplantation and the outcome following the surgery. Whether optimization of nutritional status in patients awaiting LT is associated with improved outcomes after transplant is the focus of this review. This includes the use of specialized regimens such as immune-enhancing or branchedchain amino-acids-enhanced diets.</p><p><strong>Results and conclusion: </strong>we discuss here the results of the few available studies in the field and provide an expert opinion of the obstacles that have led, so far, to an absence of benefit of such specialized regimens as compared to standard nutritional support. In the next future, combining nutritional optimization with exercise and enhanced recovery after surgery (ERAS) protocols could help optimize outcomes following liver transplantation.</p>","PeriodicalId":7322,"journal":{"name":"Acta gastro-enterologica Belgica","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9813075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between barium exposure and non-alcoholic fatty liver disease in U.S. adults. 美国成年人钡暴露与非酒精性脂肪肝的关系
IF 1.5 4区 医学
Acta gastro-enterologica Belgica Pub Date : 2023-04-01 DOI: 10.51821/86.2.11336
G Maodong, S Xin, J Luo
{"title":"Association between barium exposure and non-alcoholic fatty liver disease in U.S. adults.","authors":"G Maodong,&nbsp;S Xin,&nbsp;J Luo","doi":"10.51821/86.2.11336","DOIUrl":"https://doi.org/10.51821/86.2.11336","url":null,"abstract":"<p><strong>Background and aims: </strong>There are very limited studies that have investigated the influence of environmental barium exposure on non-alcoholic fatty liver disease (NAFLD) in the general adult population. The purpose of the present paper was to examine any correlation between urinary barium levels (UBLs) and the risk of NAFLD.</p><p><strong>Patients and methods: </strong>A total of 4,556 participants aged ≥ 20 years were recruited from the National Health and Nutritional Survey. NAFLD was defined as the U.S. fatty liver index (USFLI) ≥ 30 in the absence of other chronic liver disease. Multivariate logistic regression was conducted to inspect the correlation between UBLs and the risk of NAFLD.</p><p><strong>Results: </strong>The outcome of adjusting covariates revealed a positive correlation between the natural log -transformed UBLs (Ln-UBLs) and the risk of NAFLD (OR: 1.24, 95%CI: 1.12-1.37, P<0.001). After dividing Ln-UBLs into quartiles, the participants in the highest quartile exhibited a 1.65-fold (95% CI: 1.26-2.15) increased likelihood of having NAFLD in contrast with the bottom quartile in the full model, and a distinct trend across the quartiles could be found (P for trend<0.001). Moreover, in the interaction analyses, it was further observed that the association between Ln-UBLs and NAFLD was modified by gender and was noticeably more pronounced in males (P for interaction =0.003).</p><p><strong>Conclusions: </strong>Our findings provided evidence of a positive correlation between UBLs and the prevalence of NAFLD. Furthermore, this association changed across gender and was more pronounced in males. Nevertheless, our finding requires further confirmation with prospective cohort studies in the future.</p>","PeriodicalId":7322,"journal":{"name":"Acta gastro-enterologica Belgica","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9867284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical nutrition, skeletal muscle and liver disease: linking the dots for good management. 临床营养,骨骼肌和肝脏疾病:链接点为良好的管理。
IF 1.5 4区 医学
Acta gastro-enterologica Belgica Pub Date : 2023-04-01 DOI: 10.51821/86.1.12052
N Lanthier, S Lefere, H De Schepper, C Reenaers
{"title":"Clinical nutrition, skeletal muscle and liver disease: linking the dots for good management.","authors":"N Lanthier,&nbsp;S Lefere,&nbsp;H De Schepper,&nbsp;C Reenaers","doi":"10.51821/86.1.12052","DOIUrl":"https://doi.org/10.51821/86.1.12052","url":null,"abstract":"This is not new. The famous phrase “Let your food be your medicine and your medicine be your food” is attributed to Hippocrates of Kos in ancient Greece (1). In the mid-twentieth century, based on their clinical experience, two surgeons, Charles Child and Jeremiah Turcotte, took into account the nutritional status (later replaced by the INR to obtain an objective numerical value) to calculate the well-known score assessing the mortality risk of the cirrhotic patient (2).","PeriodicalId":7322,"journal":{"name":"Acta gastro-enterologica Belgica","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10169775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Belgian guidelines for pathology reporting of neuroendocrine neoplasms of the pancreaticobiliary and gastrointestinal tract. 比利时胰胆管和胃肠道神经内分泌肿瘤病理报告指南。
IF 1.5 4区 医学
Acta gastro-enterologica Belgica Pub Date : 2023-04-01 DOI: 10.51821/86.2.11309
A Hoorens, I Borbath, T Vandamme, C Verslype, P Demetter, P J Cuyle, S Ribeiro, N Van Damme, K P Geboes
{"title":"Belgian guidelines for pathology reporting of neuroendocrine neoplasms of the pancreaticobiliary and gastrointestinal tract.","authors":"A Hoorens,&nbsp;I Borbath,&nbsp;T Vandamme,&nbsp;C Verslype,&nbsp;P Demetter,&nbsp;P J Cuyle,&nbsp;S Ribeiro,&nbsp;N Van Damme,&nbsp;K P Geboes","doi":"10.51821/86.2.11309","DOIUrl":"https://doi.org/10.51821/86.2.11309","url":null,"abstract":"<p><p>Since neuroendocrine neoplasms are rare tumors, registration of patient data in national and multinational registries is recommended. Indeed, this will facilitate multicenter studies on the epidemiology, efficacy and safety of diagnostic and therapeutic strategies for well-differentiated neuroendocrine tumors as well as for neuroendocrine carcinomas. In Belgium, data on patient and tumor characteristics of all newly diagnosed malignancies have been collected in the Belgian Cancer Registry since 2004 including anonymized full pathological reports. The Digestive Neuroendocrine Tumor (DNET) registry collects information on classification, staging, diagnostic tools and treatment in a prospective national online database. However, the terminology, classification and staging systems of neuroendocrine neoplasms have changed repeatedly over the past 20 years as a result of a better understanding of these rare tumors, by joining forces internationally. These frequent changes make it very difficult to exchange data or perform retrospective analyses. For optimal decision making, for a clear understanding and to allow reclassification according to the latest staging system, several items need to be described in the pathology report. This paper provides an overview of the essential items in reporting neuroendocrine neoplasms of the pancreaticobiliary and gastrointestinal tract.</p>","PeriodicalId":7322,"journal":{"name":"Acta gastro-enterologica Belgica","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10169774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Obscure digestive bleeding. 不明显的消化道出血。
IF 1.5 4区 医学
Acta gastro-enterologica Belgica Pub Date : 2023-04-01 DOI: 10.51821/86.2.11669
L Hurtado-Pardo, M Bruna Esteban, J C González López, F Mingol-Navarro, J Vaqué Urbaneja
{"title":"Obscure digestive bleeding.","authors":"L Hurtado-Pardo,&nbsp;M Bruna Esteban,&nbsp;J C González López,&nbsp;F Mingol-Navarro,&nbsp;J Vaqué Urbaneja","doi":"10.51821/86.2.11669","DOIUrl":"https://doi.org/10.51821/86.2.11669","url":null,"abstract":"<p><p>A 50-year-old woman presented to the emergency department with several episodes of melena in the last week. The patient was not hemodynamically compromised and was conservatively managed. Urgent upper gastrointestinal endoscopy and colonoscopy showed no source of bleeding. Abdominal CT demonstrated three mural nodular lesions up to 2cm in the mid jejunum with hypervascular characteristics in arterial phase without active bleeding in venous phase. Angiography (Figure 1A) revealed three tumours with neo-angiogenesis and no active bleeding. Each lesion was stained with methylene blue and followed by embolization with coils. Exploratory laparotomy (Figure 1B) showed the three nodules marked by angiography. Intestinal resection of the affected segment was performed. Histopathological study proved the diagnosis of suspicion (Figure 2).</p>","PeriodicalId":7322,"journal":{"name":"Acta gastro-enterologica Belgica","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10188531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immune checkpoint inhibitor refractory colitis leading to total colectomy in a melanoma patient. 免疫检查点抑制剂难治性结肠炎导致黑色素瘤患者全结肠切除术。
IF 1.5 4区 医学
Acta gastro-enterologica Belgica Pub Date : 2023-04-01 DOI: 10.51821/86.2.10400
N Baczewska, M Philippart, J Siplet, J-F Baurain, L Stainier, E Laterre, L Duck, J-C Coche
{"title":"Immune checkpoint inhibitor refractory colitis leading to total colectomy in a melanoma patient.","authors":"N Baczewska,&nbsp;M Philippart,&nbsp;J Siplet,&nbsp;J-F Baurain,&nbsp;L Stainier,&nbsp;E Laterre,&nbsp;L Duck,&nbsp;J-C Coche","doi":"10.51821/86.2.10400","DOIUrl":"https://doi.org/10.51821/86.2.10400","url":null,"abstract":"<p><p>Immunotherapy is becoming more and more relevant in the treatment of advanced melanoma. Proper management of its side effects can prevent severe complications. We describe the case of a 73-year-old patient with severe refractory colitis secondary to immunotherapy. The patient has been treated for 6 months with Nivolumab, an anti-PD-1, as adjuvant therapy for locally advanced melanoma. He was admitted to the hospital with a deteriorating general condition associated with severe diarrhea and rectal bleeding for 3 weeks. Despite three lines of treatment (high dose corticosteroids, infliximab, mycophenolate mofetil), the patient still presented clinical and endoscopic colitis, with additional infectious complications. The patient required surgical management for total colectomy. In this article we present one of the rare cases of autoimmune colitis that did not respond to various immunosuppressive treatments and required surgery.</p>","PeriodicalId":7322,"journal":{"name":"Acta gastro-enterologica Belgica","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9867283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Endoscopic ultrasound-guided biliary drainage for distal malignant biliary obstruction: a prospective 3-year multicenter Egyptian study. 超声内镜引导下胆道引流治疗远端恶性胆道梗阻:一项为期3年的埃及多中心前瞻性研究。
IF 1.5 4区 医学
Acta gastro-enterologica Belgica Pub Date : 2023-01-01 DOI: 10.51821/86.1.10828
K M Ragab, M Abdel-Hameed, M Gouda, H Katamish, A Madkour, H Atalla, H Hamed, G E Shiha, O Abdallah, R H Agwa, E Ghoneem
{"title":"Endoscopic ultrasound-guided biliary drainage for distal malignant biliary obstruction: a prospective 3-year multicenter Egyptian study.","authors":"K M Ragab,&nbsp;M Abdel-Hameed,&nbsp;M Gouda,&nbsp;H Katamish,&nbsp;A Madkour,&nbsp;H Atalla,&nbsp;H Hamed,&nbsp;G E Shiha,&nbsp;O Abdallah,&nbsp;R H Agwa,&nbsp;E Ghoneem","doi":"10.51821/86.1.10828","DOIUrl":"https://doi.org/10.51821/86.1.10828","url":null,"abstract":"<p><strong>Background/aim: </strong>Malignant biliary obstruction (MBO) is often diagnosed at late stages with mostly unresectable lesions. Recently, EUS-guided biliary drainage (EUS-BD) has gained wide acceptance and appears to be a feasible and safe backup option after ERCP failure in such patients. Herein, we aimed to represent a 3-year multi-center Egyptian experience in the application of this challenging procedure for distal MBO as a salvage technique after failed ERCP.</p><p><strong>Patients and methods: </strong>This was a prospective multi-center study of patients underwent EUS-BD for distal MBO in the duration between December 2018 and December 2021, after ERCP failure.</p><p><strong>Results: </strong>Ninety-one patients (59 males, median age: 61 years) were included in the study. EUS-guided extrahepatic approach including choledocho-duodenostomy (CDS) was done for 48 patients (52.8%), followed by choledecho-antrostomy (CAS) in 4 patients (4.4%). The intrahepatic approach included hepaticogastrostomy (HGS) for 35 patients (38.5%) and antegrade stenting (AG) stenting in 2 patients (2.2%), while Rendezvous (RV) approach was performed in 2 patients (2.2%). Technical and Clinical success were achieved in the majority of cases; 93.4% and 94.1% respectively. Adverse events occurred in 13.2% of patients which were mostly mild (8.2%) to moderate (2.4%). Only one patient died within 48h after the procedure with progression of preceding sepsis and organ failure.</p><p><strong>Conclusion: </strong>EUS-BD is a feasible option, even in developing countries, after a failed ERCP, and it is a relatively safe option in patients with MBO once experienced team and resources were present. Majority of cases in our study have achieved technical and clinical success with relatively low incidence of adverse events.</p>","PeriodicalId":7322,"journal":{"name":"Acta gastro-enterologica Belgica","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9355290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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