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Diverticulitis associated pancreatitis: a report of 2 cases and review of the literature. 憩室炎相关性胰腺炎:附2例报告并文献复习。
IF 1.5 4区 医学
Acta gastro-enterologica Belgica Pub Date : 2023-04-01 DOI: 10.51821/86.2.11616
H Colin, D Ndjekembo Shango, B Pilet, F Waignein, P Yengue
{"title":"Diverticulitis associated pancreatitis: a report of 2 cases and review of the literature.","authors":"H Colin,&nbsp;D Ndjekembo Shango,&nbsp;B Pilet,&nbsp;F Waignein,&nbsp;P Yengue","doi":"10.51821/86.2.11616","DOIUrl":"https://doi.org/10.51821/86.2.11616","url":null,"abstract":"<p><p>Duodenal diverticula are the second most common type of digestive diverticula after those in the colon. They are present in approximately 27% of patients who undergo upper digestive endoscopy. Most of these diverticula, especially those located near the papilla, are asymptomatic. However, in rare cases, they can be associated with obstructive jaundice (Lemmel Syndrome), bacterial infection, pancreatitis, or bleeding. In this report, we present two cases of acute obstructive pancreatitis caused by duodenal diverticulitis. Both patients were managed conservatively, resulting in a positive outcome.</p>","PeriodicalId":7322,"journal":{"name":"Acta gastro-enterologica Belgica","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9813076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tofacitinib for celiac disease and microscopic colitis: killing two birds with one stone. 托法替尼治疗乳糜泻和显微镜下结肠炎：一举两得。
IF 1.5 4区 医学
Acta gastro-enterologica Belgica Pub Date : 2023-04-01 DOI: 10.51821/86.2.11639
M Lenfant, G De Hertogh, B Verstockt
{"title":"Tofacitinib for celiac disease and microscopic colitis: killing two birds with one stone.","authors":"M Lenfant,&nbsp;G De Hertogh,&nbsp;B Verstockt","doi":"10.51821/86.2.11639","DOIUrl":"10.51821/86.2.11639","url":null,"abstract":"<p><p>Microscopic colitis is a chronic inflammatory condition of the colon. Firstline treatment consists of budesonide, with the consideration of biological agents in refractory cases. Celiac disease is a chronic immune mediated and gluten-induced enteropathy, with treatment consisting of a gluten-free diet. There is an association between microscopic colitis and instead of xand celiac disease, especially in refractory cases they can coincide. In this manuscript, we report for the first time the efficacy of tofacitinib, a pan Janus kinase inhibitor, in the treatment of concomitant microscopic colitis and celiac disease, resulting in persistent clinical and histological remission.</p>","PeriodicalId":7322,"journal":{"name":"Acta gastro-enterologica Belgica","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10169778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Motorized spiral enteroscopy: effectiveness when used for new indications. 电动螺旋肠镜检查:用于新适应症的有效性。
IF 1.5 4区 医学
Acta gastro-enterologica Belgica Pub Date : 2023-04-01 DOI: 10.51821/86.2.11779
H Colin, A Donati, L Monino, T G Moreels
{"title":"Motorized spiral enteroscopy: effectiveness when used for new indications.","authors":"H Colin,&nbsp;A Donati,&nbsp;L Monino,&nbsp;T G Moreels","doi":"10.51821/86.2.11779","DOIUrl":"https://doi.org/10.51821/86.2.11779","url":null,"abstract":"<p><strong>Background and study aims: </strong>Motorized spiral enteroscopy is proven to be effective in antegrade and retrograde enteroscopy. Nevertheless, little is known about its use in less common indications. The aim of this study was to identify new indications for the motorized spiral enteroscope.</p><p><strong>Methods: </strong>Monocentric retrospective analysis of 115 patients who underwent enteroscopy using PSF-1 motorized spiral enteroscope between January 2020 and December 2022.</p><p><strong>Results: </strong>A total of 115 patients underwent PSF-1 enteroscopy. 44 (38%) were antegrade procedures and 24 (21%) were retrograde procedures in patients with normal gastrointestinal anatomy with conventional enteroscopy indications. The remaining 47 (41%) patients underwent PSF-1 procedures for secondary less conventional indications: n=25 (22%) enteroscopy-assisted ERCP, n=8 (7%) endoscopy of the excluded stomach after Roux-en-Y gastric bypass, n=7 (6%) retrograde enteroscopy after previous incomplete conventional colonoscopy and n=7 (6%) antegrade panenteroscopy of the entire small bowel. In this group of secondary indications, technical success rate was significantly lower (72.5%) as compared to technical success rates in the conventional groups (98-100%, p<0.001 Chi-square). Minor adverse events occurred in 17/115 patients (15%), all treated conservatively (AGREE I and II).</p><p><strong>Conclusion: </strong>This study demonstrates the capabilities of PSF-1 motorized spiral enteroscope for secondary indications. PSF-1 is useful to complete colonoscopy in case of long redundant colon, to reach the excluded stomach after Roux-en-Y gastric bypass, to perform unidirectional pan-enteroscopy and to perform ERCP in patients with surgically altered anatomy. However, technical success rates are lower as compared to conventional antegrade and retrograde enteroscopy procedures, with only minor adverse events.</p>","PeriodicalId":7322,"journal":{"name":"Acta gastro-enterologica Belgica","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10169781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sarcopenia in end-stage liver disease and after liver transplantation. 终末期肝病和肝移植后的肌肉减少症。
IF 1.5 4区 医学
Acta gastro-enterologica Belgica Pub Date : 2023-04-01 DOI: 10.51821/86.2.11412
S Leunis, M Vandecruys, A H Van Craenenbroeck, V Cornelissen, S Bogaerts, S De Smet, D Monbaliu
{"title":"Sarcopenia in end-stage liver disease and after liver transplantation.","authors":"S Leunis,&nbsp;M Vandecruys,&nbsp;A H Van Craenenbroeck,&nbsp;V Cornelissen,&nbsp;S Bogaerts,&nbsp;S De Smet,&nbsp;D Monbaliu","doi":"10.51821/86.2.11412","DOIUrl":"https://doi.org/10.51821/86.2.11412","url":null,"abstract":"<p><p>Sarcopenia occurs in 30-70% of patients with end-stage liver disease and is associated with inferior pre- and post-liver transplant outcomes such as prolonged intubation times, long intensive care and hospitalization times, heightened risk of post-transplant infection, reduced health-related quality of life, and increased rates of mortality. The pathogenesis of sarcopenia is multifactorial and involves biochemical disturbances such as hyperammonemia, low serum concentrations of branched-chain amino acids (BCAAs) and low serum levels of testosterone, as well as chronic inflammation, inadequate nutritional status, and physical inactivity. Prompt recognition and accurate assessment of sarcopenia are critical and require imaging, dynamometry, and physical performance testing for the assessment of its subcomponents: muscle mass, muscle strength, and muscle function, respectively. Liver transplantation mostly fails to reverse sarcopenia in sarcopenic patients. In fact, some patients develop de novo sarcopenia after undergoing liver transplantation. The recommended treatment of sarcopenia is multimodal and includes a combination of exercise therapy and complementary nutritional interventions. Additionally, new pharmacological agents (e.g. myostatin inhibitors, testosterone supplements, and ammonia-lowering therapy) are under investigation in preclinical studies. Here, we present a narrative review of the definition, assessment, and management of sarcopenia in patients with end-stage liver disease prior to and after liver transplantation.</p>","PeriodicalId":7322,"journal":{"name":"Acta gastro-enterologica Belgica","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10169773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hyperferritinemia and non-HFE hemochromatosis: differential diagnosis and workup. 高铁素血症和非hfe血色素沉着症:鉴别诊断和检查。
IF 1.5 4区 医学
Acta gastro-enterologica Belgica Pub Date : 2023-04-01 DOI: 10.51821/86.2.11249
E Lommaert, W Verlinden, I Duysburgh, T Holvoet, J Schouten
{"title":"Hyperferritinemia and non-HFE hemochromatosis: differential diagnosis and workup.","authors":"E Lommaert,&nbsp;W Verlinden,&nbsp;I Duysburgh,&nbsp;T Holvoet,&nbsp;J Schouten","doi":"10.51821/86.2.11249","DOIUrl":"https://doi.org/10.51821/86.2.11249","url":null,"abstract":"<p><p>Hyperferritinemia is a common reason for referral to a hepatogastroenterologist. The most frequent causes are not associated with iron overload (e.g. inflammatory diseases, alcohol abuse, metabolic syndrome, etc.). However, hyperferritinemia can also be caused by a genetic variant in one of the iron regulatory genes, called hereditary hemochromatosis, often but not always associated with iron overload. A variation in the human Hemostatic Iron Regulator protein (HFE) gene is the most common genotype, but many other variants have been described. In this paper we discuss two cases of rare hyperferritinemia associated disorders, ferroportin disease and hyperferritinemia-cataract syndrome. We also propose an algorithm for evaluating hyperferritinemia, facilitating a correct diagnosis and preventing potentially unnecessary examinations and therapeutic actions.</p>","PeriodicalId":7322,"journal":{"name":"Acta gastro-enterologica Belgica","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10169776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Liver health and the interplay between obesity, alcohol and bariatric surgery. 肝脏健康以及肥胖、酒精和减肥手术之间的相互作用。
IF 1.5 4区 医学
Acta gastro-enterologica Belgica Pub Date : 2023-04-01 DOI: 10.51821/86.2.11553
A Geerts, L Onghena, S Lefere
{"title":"Liver health and the interplay between obesity, alcohol and bariatric surgery.","authors":"A Geerts,&nbsp;L Onghena,&nbsp;S Lefere","doi":"10.51821/86.2.11553","DOIUrl":"https://doi.org/10.51821/86.2.11553","url":null,"abstract":"<p><p>The prevalence of obesity and metabolic consequences, including non-alcoholic fatty liver disease (NAFLD) has become a global health problem. Obesity has an important impact on chronic liver disease even beyond NAFLD, as it accelerates the progression of alcohol liver disease. Conversely, even moderate alcohol use can affect NAFLD disease severity. Weight loss is the gold standard treatment but adherence to lifestyle changes is very low in the clinical setting. Bariatric surgery can improve metabolic components and cause long-term weight loss. Therefore, bariatric surgery could serve as an attractive treatment option for NAFLD patients. A pitfall is the use of alcohol after bariatric surgery. This short review integrates data about the influence of obesity and alcohol on liver function and the role of bariatric surgery.</p>","PeriodicalId":7322,"journal":{"name":"Acta gastro-enterologica Belgica","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10169780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Respiratory involvement in Crohn's disease: a case report. 克罗恩病累及呼吸系统1例
IF 1.5 4区 医学
Acta gastro-enterologica Belgica Pub Date : 2023-04-01 DOI: 10.51821/86.2.7758
T Taelman, T Hendrickx, S Derijcke, W Van Moerkercke
{"title":"Respiratory involvement in Crohn's disease: a case report.","authors":"T Taelman,&nbsp;T Hendrickx,&nbsp;S Derijcke,&nbsp;W Van Moerkercke","doi":"10.51821/86.2.7758","DOIUrl":"https://doi.org/10.51821/86.2.7758","url":null,"abstract":"<p><p>Inflammatory bowel disease (IBD) predominantly affects the gastro-intestinal tract. There is however a large array of extra intestinal manifestations (EIM) associated with these diseases. A lesser known EIM is pulmonary involvement, which has been first described in 1973. Since the introduction of HRCT more attention is guided towards this specific involvement. Awareness of pulmonary involvement in IBD-patients may lead to better screening, guide appropriate therapy, and ultimately result in better patient care. When untreated, serious and persisting complications, such as stenosis or strictures of the large airways, as well as bronchiectasis or bronchiolitis obliterans might occur.</p>","PeriodicalId":7322,"journal":{"name":"Acta gastro-enterologica Belgica","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10188532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nutritional status in hepatic encephalopathy and transjugular intrahepatic portosystemic shunt - TIPS, and strategies to improve the outcomes. 肝性脑病和经颈静脉肝内门静脉分流术的营养状况及改善预后的策略。
IF 1.5 4区 医学
Acta gastro-enterologica Belgica Pub Date : 2023-04-01 DOI: 10.51821/86.2.11430
M Berenguer
{"title":"Nutritional status in hepatic encephalopathy and transjugular intrahepatic portosystemic shunt - TIPS, and strategies to improve the outcomes.","authors":"M Berenguer","doi":"10.51821/86.2.11430","DOIUrl":"https://doi.org/10.51821/86.2.11430","url":null,"abstract":"<p><p>Hepatic encephalopathy (HE) is one of the most severe complications following transjugular intrahepatic portosystemic shunt (TIPS). The identification and treatment of risk factors associated with the development of this complication may reduce the incidence and severity of post-TIPS HE. Several studies have demonstrated that the nutritional status plays a major role in the outcome of the cirrhotic population, particularly those who are decompensated. Although scarce, there are also studies highlighting an association between poor nutritional status, sarcopenia, fragile status, and post-TIPS HE. If these data are confirmed, nutritional support could become a means for decreasing this complication, thereby enhancing the use of TIPs in the treatment of refractory ascites or variceal bleeding. In this review, we will discuss the pathogenesis of HE, the data that supports an association with sarcopenia, nutritional status and frailty and the implications that these conditions have on the use of TIPS in clinical practice.</p>","PeriodicalId":7322,"journal":{"name":"Acta gastro-enterologica Belgica","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9813074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unexpected outcome of a sigmoid lesion believed to be malignant. 乙状结肠病变被认为是恶性的意外结果。
IF 1.5 4区 医学
Acta gastro-enterologica Belgica Pub Date : 2023-04-01 DOI: 10.51821/86.2.11927
K Ferdinande, L Harlet, J Decaestecker, D De Wulf
{"title":"Unexpected outcome of a sigmoid lesion believed to be malignant.","authors":"K Ferdinande,&nbsp;L Harlet,&nbsp;J Decaestecker,&nbsp;D De Wulf","doi":"10.51821/86.2.11927","DOIUrl":"https://doi.org/10.51821/86.2.11927","url":null,"abstract":"A 69-year-old male with a past medical history of an Olfactory nerve meningioma and left-sided Bell's palsy presented with 6 weeks of lower abdominal pain and weight loss of 4 kg in 6 months. His current medications included acetylsalicylic acid 80 mg once daily, Amlodipine 5 mg once daily and Allopurinol 300 mg once daily. Physical examination was benign without signs of acute abdomen. The abdomen was nondistended and soft but tender to palpation over the left lower quadrant. Laboratory studies showed no acute outliers. The patient was followed up by his pulmonologist because of thoracic lesions which required a PET-CT for further evaluation. This PET-CT revealed a focal zone of oedematous rectosigmoid colon with a strong suspicion of a semi-circular sigmoid neoplasia with continuation to the bladder (Figure 1a). A presumptive diagnosis of a primary colonic malignancy was made. Colonoscopy was performed and visualised a foreign linear object lodged in both walls of the diverticular sigmoid with surrounding inflammation, but otherwise normal mucosa (Figure 1b). No arguments could be made endoscopically to support the diagnosis of an underlying primary colonic malignancy.","PeriodicalId":7322,"journal":{"name":"Acta gastro-enterologica Belgica","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9867286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diet and non-alcoholic fatty liver disease, a short narrative review. 饮食与非酒精性脂肪肝的关系
IF 1.5 4区 医学
Acta gastro-enterologica Belgica Pub Date : 2023-04-01 DOI: 10.51821/86.2.11547
W J Kwanten
{"title":"Diet and non-alcoholic fatty liver disease, a short narrative review.","authors":"W J Kwanten","doi":"10.51821/86.2.11547","DOIUrl":"https://doi.org/10.51821/86.2.11547","url":null,"abstract":"<p><p>The growing importance of non-alcoholic fatty liver disease (NAFLD), the biggest non-communicable liver disease, inherently leads to an increased attention to lifestyle and diet that are closely intertwined with NAFLD. Elements of the Western diet such as saturated fats and carbohydrates and thus soft drinks, red meat and ultra-processed foods are linked to NAFLD. Contrarily, diets rich in nuts, fruits, vegetables and unsaturated fats as seen in the Mediterranean diet are linked to less prevalent and less severe NAFLD. In the absence of approved medical therapy for NAFLD, therapy mostly focusses on lifestyle and diet. This short review tries to provide a succinct overview of the current knowledge on the influence of certain diets or individual nutrients on NAFLD and discusses different dietary approaches. It ends with a short list of recommendations that can be used in daily practice.</p>","PeriodicalId":7322,"journal":{"name":"Acta gastro-enterologica Belgica","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9867288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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