Sylvie Bernaerts, Tom Van Daele, Christian Korthé Carlsen, Søren Lange Nielsen, Jolanda Schaap, Yvette Roke
{"title":"User involvement in digital mental health: approaches, potential and the need for guidelines.","authors":"Sylvie Bernaerts, Tom Van Daele, Christian Korthé Carlsen, Søren Lange Nielsen, Jolanda Schaap, Yvette Roke","doi":"10.3389/fdgth.2024.1440660","DOIUrl":"10.3389/fdgth.2024.1440660","url":null,"abstract":"","PeriodicalId":73078,"journal":{"name":"Frontiers in digital health","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11374771/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142141914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Telemedicine in the post-COVID era: balancing accessibility, equity, and sustainability in primary healthcare.","authors":"Waseem Jerjes, Daniel Harding","doi":"10.3389/fdgth.2024.1432871","DOIUrl":"10.3389/fdgth.2024.1432871","url":null,"abstract":"","PeriodicalId":73078,"journal":{"name":"Frontiers in digital health","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11371753/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142134660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jennifer Apolinário-Hagen, Giulia Paganin, Silvia Simbula
{"title":"Editorial: Current status of and future directions for assessing technology acceptance for digital (mental) health interventions.","authors":"Jennifer Apolinário-Hagen, Giulia Paganin, Silvia Simbula","doi":"10.3389/fdgth.2024.1467297","DOIUrl":"https://doi.org/10.3389/fdgth.2024.1467297","url":null,"abstract":"","PeriodicalId":73078,"journal":{"name":"Frontiers in digital health","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11368865/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142127558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andreas Trojan, Emanuele Laurenzi, Stephan Jüngling, Sven Roth, Michael Kiessling, Ziad Atassi, Yannick Kadvany, Meinrad Mannhart, Christian Jackisch, Gerd Kullak-Ublick, Hans Friedrich Witschel
{"title":"Towards an early warning system for monitoring of cancer patients using hybrid interactive machine learning.","authors":"Andreas Trojan, Emanuele Laurenzi, Stephan Jüngling, Sven Roth, Michael Kiessling, Ziad Atassi, Yannick Kadvany, Meinrad Mannhart, Christian Jackisch, Gerd Kullak-Ublick, Hans Friedrich Witschel","doi":"10.3389/fdgth.2024.1443987","DOIUrl":"https://doi.org/10.3389/fdgth.2024.1443987","url":null,"abstract":"<p><strong>Background: </strong>The use of smartphone apps in cancer patients undergoing systemic treatment can promote the early detection of symptoms and therapy side effects and may be supported by machine learning (ML) for timely adaptation of therapies and reduction of adverse events and unplanned admissions.</p><p><strong>Objective: </strong>We aimed to create an Early Warning System (EWS) to predict situations where supportive interventions become necessary to prevent unplanned visits. For this, dynamically collected standardized electronic patient reported outcome (ePRO) data were analyzed in context with the patient's individual journey. Information on well-being, vital parameters, medication, and free text were also considered for establishing a hybrid ML model. The goal was to integrate both the strengths of ML in sifting through large amounts of data and the long-standing experience of human experts. Given the limitations of highly imbalanced datasets (where only very few adverse events are present) and the limitations of humans in overseeing all possible cause of such events, we hypothesize that it should be possible to combine both in order to partially overcome these limitations.</p><p><strong>Methods: </strong>The prediction of unplanned visits was achieved by employing a white-box ML algorithm (i.e., rule learner), which learned rules from patient data (i.e., ePROs, vital parameters, free text) that were captured via a medical device smartphone app. Those rules indicated situations where patients experienced unplanned visits and, hence, were captured as alert triggers in the EWS. Each rule was evaluated based on a cost matrix, where false negatives (FNs) have higher costs than false positives (FPs, i.e., false alarms). Rules were then ranked according to the costs and priority was given to the least expensive ones. Finally, the rules with higher priority were reviewed by two oncological experts for plausibility check and for extending them with additional conditions. This hybrid approach comprised the application of a sensitive ML algorithm producing several potentially unreliable, but fully human-interpretable and -modifiable rules, which could then be adjusted by human experts.</p><p><strong>Results: </strong>From a cohort of 214 patients and more than 16'000 available data entries, the machine-learned rule set achieved a recall of 19% on the entire dataset and a precision of 5%. We compared this performance to a set of conditions that a human expert had defined to predict adverse events. This \"human baseline\" did not discover any of the adverse events recorded in our dataset, i.e., it came with a recall and precision of 0%. Despite more plentiful results were expected by our machine learning approach, the involved medical experts a) had understood and were able to make sense of the rules and b) felt capable to suggest modification to the rules, some of which could potentially increase their precision. Suggested modifications o","PeriodicalId":73078,"journal":{"name":"Frontiers in digital health","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11349615/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142115633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Continuous remote monitoring of neurophysiologic Immersion accurately predicts mood.","authors":"Sean H Merritt, Paul J Zak","doi":"10.3389/fdgth.2024.1397557","DOIUrl":"10.3389/fdgth.2024.1397557","url":null,"abstract":"<p><p>Mental health professionals have relied primarily on clinical evaluations to identify <i>in vivo</i> pathology. As a result, mental health is largely reactive rather than proactive. In an effort to proactively assess mood, we collected continuous neurophysiologic data for ambulatory individuals 8-10 h a day at 1 Hz for 3 weeks (<i>N</i> = 24). Data were obtained using a commercial neuroscience platform (Immersion Neuroscience) that quantifies the neural value of social-emotional experiences. These data were related to self-reported mood and energy to assess their predictive accuracy. Statistical analyses quantified neurophysiologic troughs by the length and depth of social-emotional events with low values and neurophysiologic peaks as the complement. Participants in the study had an average of 2.25 (SD = 3.70, Min = 0, Max = 25) neurophysiologic troughs per day and 3.28 (SD = 3.97, Min = 0, Max = 25) peaks. The number of troughs and peaks predicted daily mood with 90% accuracy using least squares regressions and machine learning models. The analysis also showed that women were more prone to low mood compared to men. Our approach demonstrates that a simple count variable derived from a commercially-available platform is a viable way to assess low mood and low energy in populations vulnerable to mood disorders. In addition, peak Immersion events, which are mood-enhancing, may be an effective measure of thriving in adults.</p>","PeriodicalId":73078,"journal":{"name":"Frontiers in digital health","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11327156/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142001486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alberto Neri, Mara Coduri, Veronica Penza, Andrea Santangelo, Alessandra Oliveri, Enrico Turco, Mattia Pizzirani, Elisa Trinceri, Domenico Soriero, Federico Boero, Serena Ricci, Leonardo S Mattos
{"title":"A novel affordable user interface for robotic surgery training: design, development and usability study.","authors":"Alberto Neri, Mara Coduri, Veronica Penza, Andrea Santangelo, Alessandra Oliveri, Enrico Turco, Mattia Pizzirani, Elisa Trinceri, Domenico Soriero, Federico Boero, Serena Ricci, Leonardo S Mattos","doi":"10.3389/fdgth.2024.1428534","DOIUrl":"10.3389/fdgth.2024.1428534","url":null,"abstract":"<p><strong>Introduction: </strong>The use of robotic systems in the surgical domain has become groundbreaking for patients and surgeons in the last decades. While the annual number of robotic surgical procedures continues to increase rapidly, it is essential to provide the surgeon with innovative training courses along with the standard specialization path. To this end, simulators play a fundamental role. Currently, the high cost of the leading VR simulators limits their accessibility to educational institutions. The challenge lies in balancing high-fidelity simulation with cost-effectiveness; however, few cost-effective options exist for robotic surgery training.</p><p><strong>Methods: </strong>This paper proposes the design, development and user-centered usability study of an affordable user interface to control a surgical robot simulator. It consists of a cart equipped with two haptic interfaces, a VR visor and two pedals. The simulations were created using Unity, which offers versatility for expanding the simulator to more complex scenes. An intuitive teleoperation control of the simulated robotic instruments is achieved through a high-level control strategy.</p><p><strong>Results and discussion: </strong>Its affordability and resemblance to real surgeon consoles make it ideal for implementing robotic surgery training programs in medical schools, enhancing accessibility to a broader audience. This is demonstrated by the results of an usability study involving expert surgeons who use surgical robots regularly, expert surgeons without robotic surgery experience, and a control group. The results of the study, which was based on a traditional Peg-board exercise and Camera Control task, demonstrate the simulator's high usability and intuitive control across diverse user groups, including those with limited experience. This offers evidence that this affordable system is a promising solution for expanding robotic surgery training.</p>","PeriodicalId":73078,"journal":{"name":"Frontiers in digital health","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11319275/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141977400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joshua Bell, Laura M Gottlieb, Courtney R Lyles, Oanh Kieu Nguyen, Sara L Ackerman, Emilia H De Marchis
{"title":"Provision of digital devices and internet connectivity to improve synchronous telemedicine access in the U.S.: a systematic scoping review.","authors":"Joshua Bell, Laura M Gottlieb, Courtney R Lyles, Oanh Kieu Nguyen, Sara L Ackerman, Emilia H De Marchis","doi":"10.3389/fdgth.2024.1408170","DOIUrl":"10.3389/fdgth.2024.1408170","url":null,"abstract":"<p><strong>Introduction: </strong>The COVID-19 pandemic led to a dramatic increase in telemedicine use for direct patient care. Inequities in device/internet access can limit the extent to which patients can engage with telemedicine care and exacerbate health disparities. In this review, we examined existing literature on interventions designed to improve patient telemedicine access by providing digital devices including tablets, smartphones, and computers and/or internet connectivity.</p><p><strong>Methods: </strong>In this systematic scoping review, we searched four databases for peer-reviewed studies published 1/1/2000-10/19/2021 that described healthcare interventions that provided patients with devices and/or internet connectivity and reported outcomes related to telemedicine access and/or usage. Data extraction elements included: study population, setting, intervention design, details on device/connectivity provision, and outcomes evaluated.</p><p><strong>Results: </strong>Twelve articles reflecting seven unique interventions met inclusion criteria. Ten articles examined telemedicine utilization (83%) and reported improved patient show rates/utilization. Seven articles examined patient satisfaction with the interventions (58%) and reported positive experiences. Fewer articles examined health outcomes (17%; 2/12) though these also demonstrated positive results. Across included studies, study quality was low. There were no controlled trials, and the most rigorously designed studies (<i>n</i> = 4) involved pre/post-intervention assessments.</p><p><strong>Discussion: </strong>Findings from this review indicate that providing material technology supports to patients can facilitate telemedicine access, is acceptable to patients and clinicians, and can contribute to improved health outcomes. The low number and quality of existing studies limits the strength of this evidence. Future research should explore interventions that can increase equitable access to telemedicine services.</p><p><strong>Systematic review registration: </strong>https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=183442, identifier, PROSPERO: CRD42020183442.</p>","PeriodicalId":73078,"journal":{"name":"Frontiers in digital health","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11317370/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141972402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maren Helene Rinke Storetvedt, Smiti Kahlon, Karin Berg, Ingeborg Alvheim Sundfjord, T. Nordgreen
{"title":"Development of a digital mental health intervention for youth with ADHD: exploring youth perspectives on wants, needs, and barriers","authors":"Maren Helene Rinke Storetvedt, Smiti Kahlon, Karin Berg, Ingeborg Alvheim Sundfjord, T. Nordgreen","doi":"10.3389/fdgth.2024.1386892","DOIUrl":"https://doi.org/10.3389/fdgth.2024.1386892","url":null,"abstract":"Attention deficit hyperactivity disorder (ADHD) is a mental health disorder affecting five to eight percent of children and youth worldwide. Inattention, impulsivity, and hyperactivity are core symptoms, which often leads to comorbid disorders and impairments. Increased prevalence of ADHD among youth requires development of accessible and scalable interventions. Digital interventions for ADHD show promising results for adults, yet insight into youths perspectives and needs from digital ADHD interventions is lacking. This study is set in a person-based approach and explore what youths want and need from a therapist-guided digital intervention for ADHD.Exploratory individual interviews were conducted with youths aged 13–16 years diagnosed with ADHD (N = 16). Participants with an ADHD diagnosis were recruited primarily via social media. The interview guide was based on research, treatment guidelines, and clinical expertise. The study applied reflexive thematic analysis, within a Big Q framework. Codes and themes were generated in Nvivo.Four main themes and sub-themes were generated: (1) Tailoring the intervention to youths with ADHD (Push the right buttons; Stumbling blocks), (2) Managing ADHD (Planning and Focus; Regulation and Balance; Social interactions), (3) Me and my ADHD (Insight and Understanding; Accept and Normalization), and (4) Balance between support and independence.The findings suggest that youths with ADHD prefer stimulating and interactive treatment and are aversive to overwhelming, passive content. The intervention and therapist should encourage empowerment by supporting the youths autonomy in managing their ADHD. Future research is needed to investigate feasibility for person-based approaches to digital mental health treatments. Furthermore, parent perspectives on digital treatment for youths with ADHD should be investigated.","PeriodicalId":73078,"journal":{"name":"Frontiers in digital health","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141659167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessing fall risk in osteoporosis patients: a comparative study of age-matched fallers and nonfallers.","authors":"Seong Hyun Moon, Krupa B Doshi, Thurmon Lockhart","doi":"10.3389/fdgth.2024.1387193","DOIUrl":"https://doi.org/10.3389/fdgth.2024.1387193","url":null,"abstract":"<p><p>This study aimed to investigate sway parameters and physical activity level of the age/gender-matched older adults with osteoporosis faller and nonfaller patients. By examining these factors, our objective was to understand how these faller and nonfaller groups with osteoporosis differed particularly in terms of balance capabilities and their impact on physical activity levels. We recruited 24 patients with osteoporosis: 12 who reported a fall within a year before recruitment (fallers) and 12 without falls (nonfallers). Given the close association between biochemical markers of musculoskeletal health such as serum calcium, parathyroid hormone (PTH), Vitamin D, and renal function, we compared these markers in both groups. As a result, elderly individuals with osteoporosis and with a history of falls within the preceding year indicated significantly higher sway velocity (<i>P</i> = 0.012*), sway area (<i>P</i> < 0.001*), and sway path length (<i>P</i> = 0.012*). Furthermore, fallers had significantly lower calcium (<i>P</i> = 0.02*) and Parathyroid hormone (PTH) (<i>P</i> = 0.02*), as well as higher Alkaline Phosphatase (ALP) (<i>P</i> = 0.02*) as compared to nonfallers despite similar vitamin D and creatinine levels. In conclusion, diminished biochemical factors in the osteoporosis faller group could possibly cause postural instability resulting in lower physical activity levels in the osteoporosis fall group and increasing the risk of falls.</p>","PeriodicalId":73078,"journal":{"name":"Frontiers in digital health","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11266042/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141763950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gemma Hughes, L. E. F. Johannessen, Erik Børve Rasmussen
{"title":"Editorial: Virtual presence: loneliness, technology and the production of human (dis)connectedness","authors":"Gemma Hughes, L. E. F. Johannessen, Erik Børve Rasmussen","doi":"10.3389/fdgth.2024.1445568","DOIUrl":"https://doi.org/10.3389/fdgth.2024.1445568","url":null,"abstract":"","PeriodicalId":73078,"journal":{"name":"Frontiers in digital health","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141663162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}